Basis and mechanisms of regulation of cytochrome P-450:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Berlin
Akad.-Verl.
1989
|
| Schriftenreihe: | Frontiers in biotransformation
1 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | VII, 252 S. |
| ISBN: | 3055004574 |
Internformat
MARC
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Datensatz im Suchindex
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| adam_text | FRONTIERS IN BIOTRANSFORMATION VOLUMEL BASIS AND MECHANISMS OF
REGULATION OF CYTOCHROME P-450 EDITED BY KLAUS RUCKPAUL AND HORST REIN
ACADEMY OF SCIENCES GDR TAYLOR & FRANCIS LONDON, NEW YORK AND
PHILADELPHIA 1989 CONTENTS INTRODUCTION K. RUCKPAUL AND H. REIN IV
CHAPTER 1 REGULATION MECHANISMS OF THE ACTIVITY OF THE HEPATIC
ENDOPLASMIC CYTOCHROME P-450 K. RUCKPAUL, H. REIN, AND J. BLANCK 1
CHAPTER 2 CATALYTICALLY ACTIVE METALLOPORPHYRIN MODELS FOR CYTOCHROME
P-450 D. MANSUY AND P. BATTIONI 66 CHAPTER 3 STRUCTURAL MULTIPLICITY AND
FUNCTIONAL VERSATILITY OF CYTOCHROME P-450 F. P. GUENGERICH . . . 101
CHAPTER 4 MULTIPLE ACTIVITIES OF CYTOCHROME P-450 A. I. ARCHAKOV AND A.
A. ZHUKOV 151 CHAPTER 5 THE HORMONAL AND MOLECULAR BASIS OF SEXUALLY
DIFFERENTIATED HEPATIC DRUG AND STEROID METABOLISM IN THE RAT E. T.
MORGAN AND J.-A. GUSTAFSSON 17 6 CHAPTER 6 EVOLUTION, STRUCTURE, AND
GENE REGULATION OF CYTOCHROME P-450 . . . . 195 0. GOTOH AND Y.
FUJII-KURIYAMA LIST OF AUTHORS 244 SUBJECT INDEX 246 III CHAPTER 1
REGULATION MECHANISMS OF THE ACTIVITY OF THE HEPATIC ENDOPLASMIC
CYTOCHROME P-450 K. RTTCKPAUL, H. REIN, AND J. BLANOK 1. INTRODUCTION 3
2. REGULATION AT THE MOLECULAR LEVEL 6 2.1. THE IMPORTANCE OF THE AXIAL
HEME IRON LIGANDS FOR THE HEMOPROTEIN FUNCTION 7 2.2. THE RELATION
BETWEEN SPECTRAL CHANGES AND SPIN STATE 9 2.3. THE SPIN EQUILIBRIUM OF
CYTOCHROME P-450 11 2.4. THE SIGNIFICANCE OF THE SPIN EQUILIBRIUM IN
MOLECULAR REGULATION . . 16 2.4.1. THE REDOX POTENTIAL OF CYTOCHROME
P-450 16 2.4.2. THE RELATION BETWEEN REDOX POTENTIAL AND SPIN STATE 18
2.4.3. THE SPIN/REDOX COUPLE AS REGULATOR OF THE REDUCTION REACTION . .
. 20 2.5. THE CONTROL FUNCTION OF THE SUBSTRATE 22 2.5.1. ACTIVE SITE
CHARACTERISTICS 22 2.5.2. STRUCTURE/ACTIVITY RELATIONSHIPS 24 2.6. THE
REGULATION OF- ALTERNATE PATHWAYS OF OXYGEN ACTIVATION . . . 26 3.
REGULATION AT THE MEMBRANE LEVEL 29 3.1. LIPID COMPOSITION AND PROTEIN
CONSTITUENTS OF THE ENDOPLASMIC RETI- CULUM 29 3.2. MEMBRANE FLUIDITY
AND MOBILITY OF MEMBRANE COMPONENTS . . . . 30 3.3. STRUCTURAL
PECULIARITIES OF PROTEIN/LIPID INTERACTIONS 32 3.4. FUNCTIONAL ASPECTS
OF THE COMPONENT INTERACTIONS IN THE MEMBRANE 34 3.4.1. CHARACTERISTICS
OF THE CYTOCHROME P-450 REDUCTION 35 3.4.2. REGULATION OF THE ELECTRON
TRANSFER BY REDUCTASE/CYTOCHROME P-450 INTERACTION 37 3.4.3.
PHOSPHOLIPID CONTROL OF ELECTRON TRANSFER 38 3.4.4. ELECTRON TRANSFER
AND SUBSTRATE CONVERSION 41 3.5. CYTOCHROME B 5 DEPENDENT REGULATION 43
3.6. ISOZYME INTERACTIONS AND PROTEIN COMPARTMENTATION 47 4. REGULATION
AT THE CELLULAR LEVEL 47 4.1. HISTORICAL BACKGROUND OF INDUCTION 49 4.2.
CLASSIFICATION OF INDUCERS AND MECHANISMS OF INDUCTION 49 4.3. RELATIONS
BETWEEN INDUCTION AND CHEMICAL CARCINOGENESIS . . . . 51 4.4.
POLYMORPHISM OF INDUCTION 52 5. CONCLUDING REMARKS AND OUTLOOK 53 6.
REFERENCES 55
|
| any_adam_object | 1 |
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| building | Verbundindex |
| bvnumber | BV001873942 |
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| dewey-full | 574.19'258 |
| dewey-hundreds | 500 - Natural sciences and mathematics |
| dewey-ones | 574 - [Unassigned] |
| dewey-raw | 574.19'258 |
| dewey-search | 574.19'258 |
| dewey-sort | 3574.19 3258 |
| dewey-tens | 570 - Biology |
| discipline | Chemie / Pharmazie Biologie |
| format | Book |
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| illustrated | Not Illustrated |
| indexdate | 2024-07-09T15:36:51Z |
| institution | BVB |
| isbn | 3055004574 |
| language | English |
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| physical | VII, 252 S. |
| publishDate | 1989 |
| publishDateSearch | 1989 |
| publishDateSort | 1989 |
| publisher | Akad.-Verl. |
| record_format | marc |
| series | Frontiers in biotransformation |
| series2 | Frontiers in biotransformation |
| spelling | Basis and mechanisms of regulation of cytochrome P-450 ed. by Klaus Ruckpaul ... Berlin Akad.-Verl. 1989 VII, 252 S. txt rdacontent n rdamedia nc rdacarrier Frontiers in biotransformation 1 Cytochrom P-450 (DE-588)4148705-9 gnd rswk-swf Enzymatische Regulation (DE-588)4136839-3 gnd rswk-swf Regulation (DE-588)4049075-0 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Cytochrom P-450 (DE-588)4148705-9 s Regulation (DE-588)4049075-0 s DE-604 Enzymatische Regulation (DE-588)4136839-3 s Ruckpaul, Klaus 1930- Sonstige (DE-588)105277584 oth Frontiers in biotransformation 1 (DE-604)BV001873941 1 GBV Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=001236810&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Basis and mechanisms of regulation of cytochrome P-450 Frontiers in biotransformation Cytochrom P-450 (DE-588)4148705-9 gnd Enzymatische Regulation (DE-588)4136839-3 gnd Regulation (DE-588)4049075-0 gnd |
| subject_GND | (DE-588)4148705-9 (DE-588)4136839-3 (DE-588)4049075-0 (DE-588)4143413-4 |
| title | Basis and mechanisms of regulation of cytochrome P-450 |
| title_auth | Basis and mechanisms of regulation of cytochrome P-450 |
| title_exact_search | Basis and mechanisms of regulation of cytochrome P-450 |
| title_full | Basis and mechanisms of regulation of cytochrome P-450 ed. by Klaus Ruckpaul ... |
| title_fullStr | Basis and mechanisms of regulation of cytochrome P-450 ed. by Klaus Ruckpaul ... |
| title_full_unstemmed | Basis and mechanisms of regulation of cytochrome P-450 ed. by Klaus Ruckpaul ... |
| title_short | Basis and mechanisms of regulation of cytochrome P-450 |
| title_sort | basis and mechanisms of regulation of cytochrome p 450 |
| topic | Cytochrom P-450 (DE-588)4148705-9 gnd Enzymatische Regulation (DE-588)4136839-3 gnd Regulation (DE-588)4049075-0 gnd |
| topic_facet | Cytochrom P-450 Enzymatische Regulation Regulation Aufsatzsammlung |
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