Gerontokinetics: pharmacokinetics of drugs in the elderly
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Caldwell, NJ
Telford Pr.
1988
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | X, 114 S. |
| ISBN: | 0936923156 |
Internformat
MARC
| LEADER | 00000nam a2200000 c 4500 | ||
|---|---|---|---|
| 001 | BV001770704 | ||
| 003 | DE-604 | ||
| 005 | 19960729 | ||
| 007 | t | ||
| 008 | 890725s1988 |||| 00||| eng d | ||
| 020 | |a 0936923156 |9 0-936923-15-6 | ||
| 035 | |a (OCoLC)18292234 | ||
| 035 | |a (DE-599)BVBBV001770704 | ||
| 040 | |a DE-604 |b ger |e rakddb | ||
| 041 | 0 | |a eng | |
| 049 | |a DE-12 |a DE-188 | ||
| 050 | 0 | |a RM301.5 | |
| 082 | 0 | |a 615/.7/0880565 |2 19 | |
| 100 | 1 | |a Ritschel, Wolfgang A. |d 1933-2010 |e Verfasser |0 (DE-588)122481178 |4 aut | |
| 245 | 1 | 0 | |a Gerontokinetics |b pharmacokinetics of drugs in the elderly |
| 264 | 1 | |a Caldwell, NJ |b Telford Pr. |c 1988 | |
| 300 | |a X, 114 S. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 650 | 4 | |a Médicaments - Métabolisme - Âge, Facteurs de l' | |
| 650 | 4 | |a Personnes âgées - Physiologie | |
| 650 | 4 | |a Pharmacocinétique - Facteurs liés à l'âge | |
| 650 | 4 | |a Pharmacologie gériatrique - Recherche - Méthodologie | |
| 650 | 2 | |a Préparations pharmaceutiques - Métabolisme - Sujet âgé | |
| 650 | 2 | |a Préparations pharmaceutiques - Pharmacocinétique - Sujet âgé | |
| 650 | 4 | |a Aged | |
| 650 | 4 | |a Drugs |x Metabolism |x Age factors | |
| 650 | 4 | |a Drugs |x metabolism |x in old age | |
| 650 | 4 | |a Drugs |x pharmacokinetics |x in old age | |
| 650 | 4 | |a Geriatric pharmacology |x Research |x Methodology | |
| 650 | 4 | |a Older people |x Physiology | |
| 650 | 4 | |a Pharmaceutical Preparations | |
| 650 | 4 | |a Pharmacokinetics |x Age factors | |
| 650 | 0 | 7 | |a Alter |0 (DE-588)4001446-0 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Pharmakokinetik |0 (DE-588)4115557-9 |2 gnd |9 rswk-swf |
| 689 | 0 | 0 | |a Alter |0 (DE-588)4001446-0 |D s |
| 689 | 0 | 1 | |a Pharmakokinetik |0 (DE-588)4115557-9 |D s |
| 689 | 0 | |5 DE-604 | |
| 856 | 4 | 2 | |m GBV Datenaustausch |q application/pdf |u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=001194066&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |3 Inhaltsverzeichnis |
| 999 | |a oai:aleph.bib-bvb.de:BVB01-001194066 | ||
Datensatz im Suchindex
| _version_ | 1804116264124153856 |
|---|---|
| adam_text | GERONTOKINETICS PHARMACOKINETICS OF DRUGS IN THE ELDERLY WOLFGANG A.
RITSCHEL UNIVERSITY OF CINCINNATI CINCINNATI, OHIO THE TELFORD PRESS
CALDWELL, NEW JERSEY CONTENTS PAGE PREFACE IX CHAPTER 1 PHYSIOLOGY OF
THE AGED 1 SUMMARY 1 1. INTRODUCTION 1 2. THEORIES ABOUT THE AGING
PROCESS 1 3. PHYSIOLOGICAL CHANGES DUE TO AGING 2 3.1. THE
CARDIAVASCULAR SYSTEM 4 3.2. THE NERVOUS SYSTEM 7 3.3. THE RESPIRATORY
SYSTEM 7 3.4. THE GASTROINTESTINAL SYSTEM 8 3.5. THE RENAL SYSTEM 10
3.6. OTHER ASPECTS 13 3.6.1. BODY WEIGHT AND BODY COMPOSITION 13 3.6.2.
BLOOD FLOW RATES 13 3.6.3. BINDING TO BIOLOGICAL MATERIAL 15 3.6.4.
BLOOD CHEMISTRY 15 3.6.5. RECEPTOR SENSITIVITY AND DISEASE 15 3.6.6.
SUMMARY 16 REFERENCES 16 CHAPTER 2 PHARMACOKINETICS IN THE ELDERLY 23
SUMMARY 23 1. INTRODUCTION 23 2. LIBERATION 24 3. ABSORPTION 25 4.
DISTRIBUTION 29 4.1. BODY COMPOSITION . 29 4.2. REGIONAL BLOOD FLOW 32
4.3. BINDING TO BIOLOGIC MATERIAL 33 5. METABOLISM 35 6. ELIMINATION 37
7. CLINICAL CONSEQUENCES 39 7.1. EXAMPLE 1: DIAZEPAM 40 7.2. EXAMPLE 2:
CIMETIDINE 40 VN VIII CONTENTS 7.3. EXAMPLE 3: PENTAZOCINE 41 7.4.
GENERAL REMARKS AND GUIDELINES FOR PHARMACOKINETICS IN THE AGED 42 7.5.
RECEPTOR SENSITIVITY 45 REFERENCES 45 CHAPTER 3 PHARMACOKINETIC
PARAMETERS OF DRUGS STUDIED IN THE AGED AND THEIR CLINICAL APPLICATION
49 1. INTRODUCTION 49 2. HOW TO ESTIMATE THE DOSING RATE IN THE ELDERLY?
50 3. HOW LONG WILL IT TAKE FOR AN ELDERLY SUBJECT TO COMPLETELY
ELIMINATE A DRUG FROM THE BODY? 51 4. HOW LONG DOES IT TAKE TO REACH
THERAPEUTIC STEADY STATE CONCENTRATION IN THE ELDERLY? 52 5. DO YOU
EXPECT A PROLONGATION OF THE ELIMINATION HALF-LIFE OF ANY DRUG IN THE
ELDERLY? 52 6. WILL RENAL FAILURE CAUSE ADDITIONAL PROLONGATION OF THE
ELIMINATION HALF-LIFE? 53 REFERENCES (FOR TABLE 1) 100 REFERENCES (FOR
TABLE 2) 114
|
| any_adam_object | 1 |
| author | Ritschel, Wolfgang A. 1933-2010 |
| author_GND | (DE-588)122481178 |
| author_facet | Ritschel, Wolfgang A. 1933-2010 |
| author_role | aut |
| author_sort | Ritschel, Wolfgang A. 1933-2010 |
| author_variant | w a r wa war |
| building | Verbundindex |
| bvnumber | BV001770704 |
| callnumber-first | R - Medicine |
| callnumber-label | RM301 |
| callnumber-raw | RM301.5 |
| callnumber-search | RM301.5 |
| callnumber-sort | RM 3301.5 |
| callnumber-subject | RM - Therapeutics and Pharmacology |
| ctrlnum | (OCoLC)18292234 (DE-599)BVBBV001770704 |
| dewey-full | 615/.7/0880565 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 615 - Pharmacology and therapeutics |
| dewey-raw | 615/.7/0880565 |
| dewey-search | 615/.7/0880565 |
| dewey-sort | 3615 17 6880565 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| format | Book |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>02050nam a2200517 c 4500</leader><controlfield tag="001">BV001770704</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">19960729 </controlfield><controlfield tag="007">t</controlfield><controlfield tag="008">890725s1988 |||| 00||| eng d</controlfield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">0936923156</subfield><subfield code="9">0-936923-15-6</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)18292234</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV001770704</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">rakddb</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-12</subfield><subfield code="a">DE-188</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">RM301.5</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">615/.7/0880565</subfield><subfield code="2">19</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Ritschel, Wolfgang A.</subfield><subfield code="d">1933-2010</subfield><subfield code="e">Verfasser</subfield><subfield code="0">(DE-588)122481178</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Gerontokinetics</subfield><subfield code="b">pharmacokinetics of drugs in the elderly</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Caldwell, NJ</subfield><subfield code="b">Telford Pr.</subfield><subfield code="c">1988</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">X, 114 S.</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">n</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">nc</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Médicaments - Métabolisme - Âge, Facteurs de l'</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Personnes âgées - Physiologie</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Pharmacocinétique - Facteurs liés à l'âge</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Pharmacologie gériatrique - Recherche - Méthodologie</subfield></datafield><datafield tag="650" ind1=" " ind2="2"><subfield code="a">Préparations pharmaceutiques - Métabolisme - Sujet âgé</subfield></datafield><datafield tag="650" ind1=" " ind2="2"><subfield code="a">Préparations pharmaceutiques - Pharmacocinétique - Sujet âgé</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Aged</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Drugs</subfield><subfield code="x">Metabolism</subfield><subfield code="x">Age factors</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Drugs</subfield><subfield code="x">metabolism</subfield><subfield code="x">in old age</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Drugs</subfield><subfield code="x">pharmacokinetics</subfield><subfield code="x">in old age</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Geriatric pharmacology</subfield><subfield code="x">Research</subfield><subfield code="x">Methodology</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Older people</subfield><subfield code="x">Physiology</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Pharmaceutical Preparations</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Pharmacokinetics</subfield><subfield code="x">Age factors</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Alter</subfield><subfield code="0">(DE-588)4001446-0</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Pharmakokinetik</subfield><subfield code="0">(DE-588)4115557-9</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="689" ind1="0" ind2="0"><subfield code="a">Alter</subfield><subfield code="0">(DE-588)4001446-0</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="1"><subfield code="a">Pharmakokinetik</subfield><subfield code="0">(DE-588)4115557-9</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2=" "><subfield code="5">DE-604</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="m">GBV Datenaustausch</subfield><subfield code="q">application/pdf</subfield><subfield code="u">http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=001194066&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA</subfield><subfield code="3">Inhaltsverzeichnis</subfield></datafield><datafield tag="999" ind1=" " ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-001194066</subfield></datafield></record></collection> |
| id | DE-604.BV001770704 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-09T15:35:44Z |
| institution | BVB |
| isbn | 0936923156 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-001194066 |
| oclc_num | 18292234 |
| open_access_boolean | |
| owner | DE-12 DE-188 |
| owner_facet | DE-12 DE-188 |
| physical | X, 114 S. |
| publishDate | 1988 |
| publishDateSearch | 1988 |
| publishDateSort | 1988 |
| publisher | Telford Pr. |
| record_format | marc |
| spelling | Ritschel, Wolfgang A. 1933-2010 Verfasser (DE-588)122481178 aut Gerontokinetics pharmacokinetics of drugs in the elderly Caldwell, NJ Telford Pr. 1988 X, 114 S. txt rdacontent n rdamedia nc rdacarrier Médicaments - Métabolisme - Âge, Facteurs de l' Personnes âgées - Physiologie Pharmacocinétique - Facteurs liés à l'âge Pharmacologie gériatrique - Recherche - Méthodologie Préparations pharmaceutiques - Métabolisme - Sujet âgé Préparations pharmaceutiques - Pharmacocinétique - Sujet âgé Aged Drugs Metabolism Age factors Drugs metabolism in old age Drugs pharmacokinetics in old age Geriatric pharmacology Research Methodology Older people Physiology Pharmaceutical Preparations Pharmacokinetics Age factors Alter (DE-588)4001446-0 gnd rswk-swf Pharmakokinetik (DE-588)4115557-9 gnd rswk-swf Alter (DE-588)4001446-0 s Pharmakokinetik (DE-588)4115557-9 s DE-604 GBV Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=001194066&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Ritschel, Wolfgang A. 1933-2010 Gerontokinetics pharmacokinetics of drugs in the elderly Médicaments - Métabolisme - Âge, Facteurs de l' Personnes âgées - Physiologie Pharmacocinétique - Facteurs liés à l'âge Pharmacologie gériatrique - Recherche - Méthodologie Préparations pharmaceutiques - Métabolisme - Sujet âgé Préparations pharmaceutiques - Pharmacocinétique - Sujet âgé Aged Drugs Metabolism Age factors Drugs metabolism in old age Drugs pharmacokinetics in old age Geriatric pharmacology Research Methodology Older people Physiology Pharmaceutical Preparations Pharmacokinetics Age factors Alter (DE-588)4001446-0 gnd Pharmakokinetik (DE-588)4115557-9 gnd |
| subject_GND | (DE-588)4001446-0 (DE-588)4115557-9 |
| title | Gerontokinetics pharmacokinetics of drugs in the elderly |
| title_auth | Gerontokinetics pharmacokinetics of drugs in the elderly |
| title_exact_search | Gerontokinetics pharmacokinetics of drugs in the elderly |
| title_full | Gerontokinetics pharmacokinetics of drugs in the elderly |
| title_fullStr | Gerontokinetics pharmacokinetics of drugs in the elderly |
| title_full_unstemmed | Gerontokinetics pharmacokinetics of drugs in the elderly |
| title_short | Gerontokinetics |
| title_sort | gerontokinetics pharmacokinetics of drugs in the elderly |
| title_sub | pharmacokinetics of drugs in the elderly |
| topic | Médicaments - Métabolisme - Âge, Facteurs de l' Personnes âgées - Physiologie Pharmacocinétique - Facteurs liés à l'âge Pharmacologie gériatrique - Recherche - Méthodologie Préparations pharmaceutiques - Métabolisme - Sujet âgé Préparations pharmaceutiques - Pharmacocinétique - Sujet âgé Aged Drugs Metabolism Age factors Drugs metabolism in old age Drugs pharmacokinetics in old age Geriatric pharmacology Research Methodology Older people Physiology Pharmaceutical Preparations Pharmacokinetics Age factors Alter (DE-588)4001446-0 gnd Pharmakokinetik (DE-588)4115557-9 gnd |
| topic_facet | Médicaments - Métabolisme - Âge, Facteurs de l' Personnes âgées - Physiologie Pharmacocinétique - Facteurs liés à l'âge Pharmacologie gériatrique - Recherche - Méthodologie Préparations pharmaceutiques - Métabolisme - Sujet âgé Préparations pharmaceutiques - Pharmacocinétique - Sujet âgé Aged Drugs Metabolism Age factors Drugs metabolism in old age Drugs pharmacokinetics in old age Geriatric pharmacology Research Methodology Older people Physiology Pharmaceutical Preparations Pharmacokinetics Age factors Alter Pharmakokinetik |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=001194066&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT ritschelwolfganga gerontokineticspharmacokineticsofdrugsintheelderly |