Sequence analysis in molecular biology: treasure trove or trivial pursuit
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
San Diego u.a.
Acad. Pr.
1987
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | Literaturverz. S. 165 - 184 |
| Beschreibung: | XII, 188 S. graph. Darst. |
| ISBN: | 0127251308 |
Internformat
MARC
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Datensatz im Suchindex
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| adam_text | IMAGE 1
SEQUENCE ANALYSIS
IN MOLECULAR BIOLOGY TREASURE TROVE OR TRIVIAL PURSUIT
GUNNAR VON FLEIJNE RESEARCH GROUP FOR THEORETICAL BIOPHYSICS DEPARTMENT
OF THEORETICAL PHYSICS ROYAL INSTITUTE OF TECHNOLOGY
STOCKHOLM, SWEDEN
ACADEMIC PRESS, INC HARCOURT BRACE JOVANOVLCH, PUBLISHERS SAN DIEGO NEW
YORK BERKELEY BOSTON LONDON SYDNEY TOKYO TORONTO
IMAGE 2
CONTENTS
PREFACE XI
CHAPTER 1
CHAPTER 2
CHAPTER 3
INTRODUCTION: THE ABNORMALIN STORY
THE COLLECTOR S DREAM: FROM DAYHOFF TO DATA BANKS
SEQUENCING ON THE COMPUTER: PROGRAMS THAT MAKE LAB WORK EASIER, FASTER,
AND MORE FUN (?)
I. DESIGNING OLIGONUCLEOTIDE PROBES II. CONSTRUCTING RESTRICTION MAPS
III. SEQUENCING DNA IV. FINDING RESTRICTION SITES
V. TRANSLATING DNA INTO PROTEIN VI. SIMULATING CLONING EXPERIMENTS
1
5
11 U 13 14 16 16 18
CHAPTER 4 NUCLEOTIDE SEQUENCES: WHAT YOU CANODO WITH YOUR SEQUENCE ONCE
YOU HAVE IT
I. PROTEIN - DNA INTERACTIONS AND REGULATION OF GENE EXPRESSION II.
PROMOTER SEQUENCES
VII
19
20 23
IMAGE 3
VM
III. TERMINATOR SEQUENCES IV. SPLICE SITES V. INITIATION OF PROTEIN
SYNTHESIS: RIBOSOME-BINDING SITES VI. FINDING CODING REGIONS VII. RNA
FOLDING AND STRUCTURE VIII. DNA GEOMETRY
CONTENTS
32 39
44 49 58
72
CHAPTER 5 PROTEIN SEQUENCES: WHAT YOU CAN DO WITH YOUR SEQUENCE ONCE YOU
HAVE IT 81
I.
II. III.
RV.
V.
VI. VII.
RULES OF PROTEIN STRUCTURE SECONDARY STRUCTURE PREDICTION SUPERSECONDAIY
STRUCTURE PREDICTION PREDICTING THE STRUCTURAL AND FUNCTIONAL
CLASS OF A PROTEIN THE POLAR-APOLAR NATURE OF SOLUBLE AND MEMBRANE-BOUND
PROTEINS SORTING SIGNALS IN PROTEINS COVALENT MODIFICATIONS OF PROTEINS
81 83 93
95
97 112 118
CHAPTER 6 SEQUENCE SIMILARITIES,
HOMOLOGIES, AND ALIGNMENTS 123
I. DOT-MATRIX ANALYSIS 123
II. GLOBAL ALIGNMENTS 125
III. LOCAL ALIGNMENTS 128
IV. MULTIPLE ALIGNMENTS 131
V. MEASURES OF AMINO ACID SIMILARITY 134
VI. ESTIMATING THE STATISTICAL SIGNIFICANCE OF AN ALIGNMENT 137
CHAPTER 7 MACHINE MOLECULAR BIOLOGY:
RUNNING EXPERIMENTS ON THE COMPUTER
I. PATTERNS THAT WERE NOT II. COMPUTER-GUIDED INTUITION
141
141 145
CHAPTER 8 SEQUENCES: WHERE THEORETICAL AND EXPERIMENTAL MOLECULAR
BIOLOGY MEET 151
IMAGE 4
CONTENTS IX
APPENDIX 1 MOLECULAR BIOLOGY DATABASES 153
APPENDIX 2 SOME COMMERCIALLY AVAILABLE SOFTWARE PACKAGES FOR MOLECULAR
BIOLOGY 161
BIBLIOGRAPHY 165
INDEX 185
|
| any_adam_object | 1 |
| author | Heijne, Gunnar von |
| author_facet | Heijne, Gunnar von |
| author_role | aut |
| author_sort | Heijne, Gunnar von |
| author_variant | g v h gv gvh |
| building | Verbundindex |
| bvnumber | BV001343008 |
| classification_rvk | WC 4150 WC 4460 |
| classification_tum | CHE 820f CHE 860f BIO 220f CHE 810f |
| ctrlnum | (OCoLC)185475020 (DE-599)BVBBV001343008 |
| dewey-full | 574.87328 574.87 |
| dewey-hundreds | 500 - Natural sciences and mathematics |
| dewey-ones | 574 - [Unassigned] |
| dewey-raw | 574.873 28 574.87 |
| dewey-search | 574.873 28 574.87 |
| dewey-sort | 3574.873 228 |
| dewey-tens | 570 - Biology |
| discipline | Biologie Chemie |
| format | Book |
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| illustrated | Illustrated |
| indexdate | 2024-07-09T15:27:35Z |
| institution | BVB |
| isbn | 0127251308 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-000812395 |
| oclc_num | 185475020 |
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| owner_facet | DE-12 DE-355 DE-BY-UBR DE-20 DE-91G DE-BY-TUM DE-83 DE-11 DE-188 |
| physical | XII, 188 S. graph. Darst. |
| publishDate | 1987 |
| publishDateSearch | 1987 |
| publishDateSort | 1987 |
| publisher | Acad. Pr. |
| record_format | marc |
| spelling | Heijne, Gunnar von Verfasser aut Sequence analysis in molecular biology treasure trove or trivial pursuit Gunnar von Heijne San Diego u.a. Acad. Pr. 1987 XII, 188 S. graph. Darst. txt rdacontent n rdamedia nc rdacarrier Literaturverz. S. 165 - 184 Molecular biology prvt Molekylärbiologi Molekylärbiologi prvt Datenverarbeitung Amino acid sequence Data processing Nucleotide sequence Data processing Sequenzanalyse Chemie (DE-588)4132277-0 gnd rswk-swf Nucleotide (DE-588)4135085-6 gnd rswk-swf Molekularbiologie (DE-588)4039983-7 gnd rswk-swf Datenverarbeitung (DE-588)4011152-0 gnd rswk-swf Aminosäuren (DE-588)4142205-3 gnd rswk-swf Sequenzanalyse Chemie (DE-588)4132277-0 s Datenverarbeitung (DE-588)4011152-0 s DE-604 Molekularbiologie (DE-588)4039983-7 s Aminosäuren (DE-588)4142205-3 s Nucleotide (DE-588)4135085-6 s HEBIS Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=000812395&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Heijne, Gunnar von Sequence analysis in molecular biology treasure trove or trivial pursuit Molecular biology prvt Molekylärbiologi Molekylärbiologi prvt Datenverarbeitung Amino acid sequence Data processing Nucleotide sequence Data processing Sequenzanalyse Chemie (DE-588)4132277-0 gnd Nucleotide (DE-588)4135085-6 gnd Molekularbiologie (DE-588)4039983-7 gnd Datenverarbeitung (DE-588)4011152-0 gnd Aminosäuren (DE-588)4142205-3 gnd |
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| title | Sequence analysis in molecular biology treasure trove or trivial pursuit |
| title_auth | Sequence analysis in molecular biology treasure trove or trivial pursuit |
| title_exact_search | Sequence analysis in molecular biology treasure trove or trivial pursuit |
| title_full | Sequence analysis in molecular biology treasure trove or trivial pursuit Gunnar von Heijne |
| title_fullStr | Sequence analysis in molecular biology treasure trove or trivial pursuit Gunnar von Heijne |
| title_full_unstemmed | Sequence analysis in molecular biology treasure trove or trivial pursuit Gunnar von Heijne |
| title_short | Sequence analysis in molecular biology |
| title_sort | sequence analysis in molecular biology treasure trove or trivial pursuit |
| title_sub | treasure trove or trivial pursuit |
| topic | Molecular biology prvt Molekylärbiologi Molekylärbiologi prvt Datenverarbeitung Amino acid sequence Data processing Nucleotide sequence Data processing Sequenzanalyse Chemie (DE-588)4132277-0 gnd Nucleotide (DE-588)4135085-6 gnd Molekularbiologie (DE-588)4039983-7 gnd Datenverarbeitung (DE-588)4011152-0 gnd Aminosäuren (DE-588)4142205-3 gnd |
| topic_facet | Molecular biology Molekylärbiologi Datenverarbeitung Amino acid sequence Data processing Nucleotide sequence Data processing Sequenzanalyse Chemie Nucleotide Molekularbiologie Aminosäuren |
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