Immunology, immunopathology, and immunity:
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
New York [u.a.]
Elsevier
1987
|
| Ausgabe: | 4. ed. |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | Literaturangaben |
| Beschreibung: | XVII, 852 S. Ill., graph. Darst. |
| ISBN: | 0444011374 |
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Datensatz im Suchindex
| _version_ | 1804115616846577664 |
|---|---|
| adam_text | IMAGE 1
CONTENTS
PREFACE XV PREFACE TO FIRST EDITION XVII
PART 1: IMMUNOLOGY 1
1. INTRODUCTION TO IMMUNOLOGY 3 IMMUNITY 3 INFLAMMATORY RESPONSE 7
EVOLUTION OF IMMUNITY (PHYLOGENY) 9 IMMUNOPATHOLOGY, THE DOUBLE-EDGED
SWORD 13 HISTORY OF IMMUNOLOGY AND IMMUNOPATHOLOGY 14 SUMMARY 14 GENERAL
REFERENCES 16
2. THE IMMUNE SYSTEM I: CELLS AND VESSELS 19 CELLS OF THE IMMUNE SYSTEM
19 CELLULAR INTERACTIONS IN IMMUNE RESPONSES 31 LYMPHATIC VESSELS 32
LYMPHOID ORGANS 32 SUMMARY 34
REFERENCES 35
3. THE IMMUNE SYSTEM II: ORGANS 37 CENTRAL LYMPHOID ORGANS 37 PERIPHERAL
LYMPHOID ORGANS 41 GASTROINTESTINAL AND BRONCHUS ASSOCIATED LYMPHOID
TISSUE 45 COMPARISON OF STRUCTURES OF LYMPHOID ORGANS 47 LYMPHOCYTE
CIRCULATION 48 THE EFFECT OF ANTIGENS ON LYMPHOID ORGANS 48 SUMMARY 54
REFERENCES 54 VII
IMAGE 2
CONTENTS
4. THE IMMUNE SYSTEM III: DEVELOPMENT OF LYMPHOID
ORGANS (ONTOGENY) 57 T CELL DIFFERENTIATION 57 NATURAL KILLER AND KILLER
CELLS 63 B CELL DIFFERENTIATION 64 SUMMARY 66
REFERENCES 66
5. ANTIGENICITY AND IMMUNOGENICITY 69 ANTIGENS AND IMMUNOGENS 69
IMMUNIZATION 75 ANTIGENIC SPECIFICITY 80 SUMMARY 82
REFERENCES 83
6. ANTIBODIES, IMMUNOGLOBULINS, AND RECEPTORS 85 GAMMA GLOBULIN 85
MYELOMA PROTEINS 86 IMMUNOGLOBULINS 86 ANTIBODIES 91 IMMUNOGLOBULIN
ANTIGENIC SPECIFICITIES 97 SYNTHESIS AND ASSEMBLY OF IMMUNOGLOBULINS 102
IMMUNOGLOBULIN GENE REARRANGEMENTS 102 CELL SURFACE IMMUNOGLOBULIN 105
DIFFERENTIATION OF B CELLS AND EXPRESSION OF IMMUNOGLOBULIN 106 T CELL
RECEPTOR EXPRESSION 108 ORIGIN OF IMMUNOGLOBULIN GENE DIVERSITY 109
SUMMARY 111 REFERENCES 112
7. ANTIGEN-ANTIBODY REACTIONS 117 POLYFUNCTIONAL ANTIBODY
(CROSS-REACTIONS) 117 PRIMARY ANTIGEN - ANTIBODY REACTION 119 SECONDARY
ANTIGEN-ANTIBODY REACTIONS 122 ANTIGEN-ANTIBODY REACTIONS IN VIVO 142
SENSITIVITY OF ANTIGEN - ANTIBODY REACTIONS 144 SUMMARY 144
REFERENCES 145
8. CELL-MEDIATED IMMUNITY IN VITRO 149 SENSITIZATION OF T CELLS 149
PRIMARY CELLULAR REACTION WITH ANTIGEN 150 SECONDARY EFFECTS OF ANTIGEN
ACTIVATION OF LYMPHOCYTES 153 SENSITIZATION OF KILLER CELLS IN VITRO 160
ANTIBODY-DEPENDENT CELL-MEDIATED CYTOTOXICITY 161 SUMMARY 163
REFERENCES 163
IMAGE 3
CONTENTS IX
9. THE MAJOR HISTOCOMPATIBILITY COMPLEX AND THE IMMUNOGLOBULIN GENE
SUPERFAMILY 169 SELF- NONSELF RECOGNITION 169 GENETICS OF TISSUE
TRANSPLANTATION 170 GENETIC CONTROL OF THE IMMUNE RESPONSE 171
MACROPHAGE RESTRICTION 173 STRUCTURE OF THE MAJOR HISTOCOMPATIBILITY
GENE COMPLEX 175 MHC PRODUCTS AND THE CELL SURFACE 178 THE MHC AND
TISSUE TRANSPLANTATION 183 HUMAN MHC AND DISEASE ASSOCIATIONS 190
SUMMARY 191
REFERENCES 191
10. THE IMMUNE RESPONSE 199 CELLULAR INTERACTIONS IN THE INDUCTION OF
ANTIBODY FORMATION 199 CELLULAR INTERACTIONS IN THE INDUCTION OF IMMUNE
T CELLS 205 LYMPHOID CELLLNTERACTIONS IN VIVO 215 IMMUNE MEMORY 217
CONTROL OF ANTIBODY PRODUCTION 218 THEORIES OF ANTIGEN RECOGNITION 221
SUMMARY 224
REFERENCES 225
1 1. IMMUNE TOLERANCE AND AUTOIMMUNITY 235 NATURAL TOLERANCE 235
ACQUIRED TOLERANCE 236 MECHANISMS OF TOLERANCE 240 SPLIT TOLERANCE AND
IMMUNE DEVIATION 247 IMMUNE PARALYSIS 247 DESENSITIZATION 248 TOLERANCE
AND IMMUNITY 248 AUTOIMMUNITY 249 SUMMARY 254
REFERENCES 255
12. INFLAMMATION 261 THE PROCESS OF INFLAMMATION 261 THE CELLS OF ACUTE
INFLAMMATION 267 INTERRELATIONSHIPS OF INFLAMMATORY CELLS AND SYSTEMS IN
ACUTE
INFLAMMATION 283 THE CELLS OF CHRONIC INFLAMMATION 285 THE
RETICULOENDOTHELIAL SYSTEM 293 REVIEW OF INFLAMMATORY MEDIATORS 298
MANIFESTATIONS OF INFLAMMATION IN TISSUES 299 SUMMARY 301 REFERENCES 302
IMAGE 4
CONTENTS
1 3. IMMUNE-MEDIATED INFLAMMATION 307 IMMUNE EFFECTOR MECHANISMS 307
SUMMARY 317 REFERENCES 317
PART 2: IMMUNOPATHOLOGY 319
WHY A DOUBLE-EDGED SWORD ? 320 CLASSIFICATION BY ORIGIN AND RESPONSE
AND SOURCE OF ANTIGEN 321
1 4. INACTIVATION OR ACTIVATION OF BIOLOGICALLY ACTIVE MOLECULES 323
MECHANISMS OF ANTIBODY-MEDIATED INACTIVATION 323 EXAMPLES OF
ANTIBODY-MEDIATED INACTIVATION 325 LIGANDS, RECEPTORS, AND IDIOTYPES 339
NEUTRALIZING ANTIBODIES: CAUSE AND EFFECT 342 SUMMARY 343
REFERENCES 343
1 5. CYTOTOXIC OR CYTOLYTIC REACTIONS 349 IMMUNOHEMATOLOGIC DISEASES 349
OTHER CYTOTOXIC REACTIONS 364 DEMONSTRATION OF CYTOTOXIC ANTIBODIES 365
SUMMARY 366 REFERENCES 367
1 6. IMMUNE COMPLEX REACTIONS 373 ARTHUS REACTION 374 SERUM SICKNESS 376
IMMUNE COMPLEXES IN INFECTIOUS DISEASES 378
GLOMERULONEPHRITIS 379 OTHER IMMUNE COMPLEX DISEASES 389 SKIN DISEASES
MEDIATED BY IMMUNE COMPLEX MECHANISMS 394 AMYLOIDOSIS 401 EVALUATION OF
CIRCULATING IMMUNE COMPLEXES 403 SUMMARY 404 REFERENCES 404
1 7. CONNECTIVE TISSUE (COLLAGEN-VASCULAR, RHEUMATOID) DISEASES 413
POLYARTERITIS NODOSA 415 SYSTEMIC LUPUS ERYTHEMATOSUS 416
DERMATOMYOSITIS 423 PROGRESSIVE SYSTEMIC SCLEROSIS (SCLERODERMA) 424
THROMBOTIC THROMBOCYTOPENIA PURPURA 425
RHEUMATIC FEVER 425 RHEUMATOID ARTHRITIS 427 MIXED CONNECTIVE TISSUE
DISEASE 431
IMAGE 5
CONTENTS
SUMMARY 431 REFERENCES 432
1 8. ATOPIC OR ANAPHYLACTIC REACTIONS (ALLERGY) 439 REAGINIC ANTIBODY
441 ANAPHYLAXIS 445 ATOPIC ALLERGY 448
IMMUNOTHERAPEUTIC MODIFICATION OF ATOPIC ALLERGY 455 PHARMACOLOGICAL
CONTROL OF ATOPIC REACTIONS 459 ANAPHYLACTOID REACTIONS 463 TREATMENT OF
ATOPIC ALLERGY 463
PROTECTIVE ROLE OF IGE 463 SUMMARY 465 REFERENCES 465
1 9. DELAYED HYPERSENSITIVITY REACTIONS (CELL-MEDIATED IMMUNITY) 471
DELAYED SKIN REACTIONS 473 GRAFT REJECTION 478 GRAFT VERSUS HOST
REACTIONS 487 VIRAL INFECTIONS 492 SUMMARY 499
REFERENCES 500
2 0. AUTOALLERGIC DISEASES 511 ENCEPHALOMYELITIS AND MULTIPLE SCLEROSIS
512 PERIPHERAL NEURITIS 515 PHACOANAPHYLACTIC ENDOPHTHALMITIS 515
UVEITIS 516 COGAN S SYNDROME 516
ORCHIDS 516 THYROIDITIS 517 SIALADENITIS (SJOGREN S SYNDROME; SICCA
COMPLEX) 519 ADRENALITIS AND MULTIPLE ENDOCRINE DEFICIENCY 520
ULCERATIVE COLITIS 520 LIVER DISEASE 520 PERIODONTAL DISEASE 521
ADJUVANT DISEASE 522 SUMMARY 522 REFERENCES 522
2 1. GRANULOMATOUS REACTIONS 529 THE NATURE OF GRANULOMAS 529
GRANULOMATOUS DISEASES 531 INFECTIOUS DISEASES 532 GRANULOMATOUS
RESPONSE TO KNOWN ANTIGENS 536 DISEASES OF UNKNOWN ETIOLOGY 538 IMMUNE
DEFICIENCY DISEASES: GRANULOMATOUS DISEASE OF
CHILDREN 540
IMAGE 6
X LL CONTENTS
SUMMARY 540 REFERENCES 541
2 2. INTERPLAY OF INFLAMMATORY AND IMMUNOPATHOLOGICAL MECHANISMS IN
DISEASE 545 NONIMMUNE INFLAMMATION 545 IMMUNE INFLAMMATION 545 MIXED
IMMUNOPATHOLOGIC MECHANISMS 546 INTERACTIONS OF IMMUNE AND NONIMMUNE
MECHANISMS 548
REFERENCES 549
2 3. DRUG ALLERGY 551 ALLERGIC MECHANISMS IN DRUG REACTIONS 551
SENSITIZATION TO DRUGS 553 PENICILLIN ALLERGY: THE EPITOME 556 ALLERGIC
REACTIONS TO CANCER CHEMOTHERAPEUTIC AGENTS 559
UNSUSPECTED DRUG REACTIONS TO CONTAMINANTS 560 DRUG-INDUCED LUPUS
ERYTHEMATOSUS 560 SUMMARY 561
REFERENCES 561
PART 3: IMMUNITY 563
2 4. IMMUNE RESISTANCE TO INFECTION 565 REACTIONS TO INFECTIOUS AGENTS
565 SPECIFIC PROTECTIVE IMMUNITY TO INFECTION 566 SUMMARY OF ROLE OF
IMMUNE MECHANISMS IN PROTECTION AGAINST
INFECTIONS 571 IMMUNE EFFECTOR MECHANISMS IN SPECIFIC INFECTIONS 571
EVASION OF IMMUNE DEFENSES 586 SUMMARY 587 REFERENCES 590
2 5. IMMUNIZATION 597 PASSIVE IMMUNITY 597 ACTIVE IMMUNITY 598
EVALUATION OF IMMUNIZATION 611
LIABILITY FOR VACCINE MANUFACTURE 612 IMMUNITY AS A RELATIVE CONDITION
612 SUMMARY 612 REFERENCES 613
2 6. IMMUNE DEFICIENCY DISEASES 617 DEVELOPMENT OF IMMUNE MATURITY 617
PRIMARY IMMUNE DEFICIENCIES 619 SECONDARY IMMUNE DEFICIENCIES 632
EVALUATION OF IMMUNE DEFICIENCY 639 THERAPY 642
IMAGE 7
CONTENTS
SUMMARY 647 REFERENCES 647
2 7. IMMUNE MODULATION 655 STIMULATION OF IMMUNE RESPONSES 657
SUPPRESSION OF IMMUNE RESPONSES 664 SUMMARY 681
REFERENCES 681
2 8. LYMPHOPROLIFERATIVE DISEASES 687 LYMPHOID TISSUE STRUCTURE AND
LYMPHOPROLIFERATIVE DISEASE 688 NONMALIGNANT LYMPHOPROLIFERATION 690
HUMAN LYMPHOMAS 693 ANIMAL MODELS OF LYMPHOID TUMORS 711
ETIOLOGY OF LYMPHOPROLIFERATIVE DISEASES 714 INFECTION AND
LYMPHOPROLIFERATIVE DISEASES 715 SUMMARY 716 REFERENCES 716
2 9. TUMOR IMMUNITY 725 HOST-TUMOR RELATIONSHIPS 725 TUMOR IMMUNITY IN
HUMANS 726 TUMOR ANTIGENS 729 MECHANISMS OF TUMOR CELL DESTRUCTION BY
THE IMMUNE SYSTEM 737
IMMUNE SURVEILLANCE 741 FAILURE OF IMMUNE SURVEILLANCE 742
IMMUNODIAGNOSIS OF CANCER 748 IMMUNOPROPHYLAXIS OF CANCER 763
IMMUNOTHERAPY OF CANCER 764 SUMMARY 770
REFERENCES 771
APPENDIX A: CLINICAL IMMUNOLOGY 781
APPENDIX B: CLUSTER DESIGNATIONS 787
GLOSSARY 789
INDEX 839
|
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| discipline | Biologie Medizin |
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| spelling | Sell, Stewart 1935- Verfasser (DE-588)1145532799 aut Immunology, immunopathology, and immunity Stewart Sell 4. ed. New York [u.a.] Elsevier 1987 XVII, 852 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Literaturangaben Immunology Immunité Immunologie Immunopathologie Immune System Diseases Immunity Immunopathology Immunität Medizin (DE-588)4120476-1 gnd rswk-swf Immunpathologie (DE-588)4014133-0 gnd rswk-swf Immunologie (DE-588)4026637-0 gnd rswk-swf (DE-588)4123623-3 Lehrbuch gnd-content Immunologie (DE-588)4026637-0 s DE-604 Immunität Medizin (DE-588)4120476-1 s 1\p DE-604 Immunpathologie (DE-588)4014133-0 s 2\p DE-604 SWB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=000736082&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 2\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Sell, Stewart 1935- Immunology, immunopathology, and immunity Immunology Immunité Immunologie Immunopathologie Immune System Diseases Immunity Immunopathology Immunität Medizin (DE-588)4120476-1 gnd Immunpathologie (DE-588)4014133-0 gnd Immunologie (DE-588)4026637-0 gnd |
| subject_GND | (DE-588)4120476-1 (DE-588)4014133-0 (DE-588)4026637-0 (DE-588)4123623-3 |
| title | Immunology, immunopathology, and immunity |
| title_auth | Immunology, immunopathology, and immunity |
| title_exact_search | Immunology, immunopathology, and immunity |
| title_full | Immunology, immunopathology, and immunity Stewart Sell |
| title_fullStr | Immunology, immunopathology, and immunity Stewart Sell |
| title_full_unstemmed | Immunology, immunopathology, and immunity Stewart Sell |
| title_short | Immunology, immunopathology, and immunity |
| title_sort | immunology immunopathology and immunity |
| topic | Immunology Immunité Immunologie Immunopathologie Immune System Diseases Immunity Immunopathology Immunität Medizin (DE-588)4120476-1 gnd Immunpathologie (DE-588)4014133-0 gnd Immunologie (DE-588)4026637-0 gnd |
| topic_facet | Immunology Immunité Immunologie Immunopathologie Immune System Diseases Immunity Immunopathology Immunität Medizin Immunpathologie Lehrbuch |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=000736082&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT sellstewart immunologyimmunopathologyandimmunity |