Detoxication and drug metabolism: conjugation and related systems
Gespeichert in:
Format: | Buch |
---|---|
Sprache: | English |
Veröffentlicht: |
New York u.a.
Acad. Pr.
1981
|
Schriftenreihe: | Methods in enzymology
77 |
Schlagworte: | |
Online-Zugang: | Inhaltsverzeichnis |
Beschreibung: | XXII, 476 S. Ill., graph. Darst. |
ISBN: | 0121819779 |
Internformat
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245 | 1 | 0 | |a Detoxication and drug metabolism |b conjugation and related systems |c ed. by William B. Jakoby |
264 | 1 | |a New York u.a. |b Acad. Pr. |c 1981 | |
300 | |a XXII, 476 S. |b Ill., graph. Darst. | ||
336 | |b txt |2 rdacontent | ||
337 | |b n |2 rdamedia | ||
338 | |b nc |2 rdacarrier | ||
490 | 1 | |a Methods in enzymology |v 77 | |
650 | 7 | |a Drug Metabolism |2 cabt | |
650 | 4 | |a Enzymes | |
650 | 4 | |a Médicaments - Détoxication | |
650 | 4 | |a Médicaments - Métabolisme | |
650 | 4 | |a Drugs |x Metabolic detoxification | |
650 | 4 | |a Drugs |x Metabolism | |
650 | 4 | |a Enzymes | |
650 | 4 | |a Enzymes |x isolation & purification | |
650 | 4 | |a Metabolic Detoxication, Drug | |
650 | 4 | |a Metabolic conjugation | |
650 | 4 | |a Pharmaceutical Preparations |x metabolism | |
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adam_text | IMAGE 1
TABLE OF CONTENTS
CONTRIBUTORS TO V O L U ME 77 IX
PREFACE XIII
VOLUMES IN SERIES XV
SECTION I. ANIMAL ORGAN AND CELL PREPARATIONS
A. GENERAL METHODS
1. EXHALATION OF ISOTOPIC CO 2 JOHANNES BIRCHER AND
RUDOLF PREISIG 3
2. HYDROCARBON EXHALATION ALBRECHT WENDEL AND
ERICH E. DUMELIN 10
3. MEASUREMENT OF HYDROGEN PEROXIDE FORMATION IN SITU HELMUT SIES 15
4. COLLECTION OF METABOLITES IN BILE AND URINE FROM GERARD J. MULDER,
EGBERT
THE RAT SCHOLTENS, AND
DIRK K. F. MEIJER 21
5. COLLECTION OF FECES FOR STUDIES OF XENOBIOTIC ME- TABOLISM AND
DISPOSITION HAZEL B. MATHEWS 31
6. GERMFREE RATS MARTHA A. MCLAFFERTY
AND PETER GOLDMAN 34
7. COVALENT BINDING OF ELECTROPHILIC METABOLITES TO LANCE R. POHL AND
MACROMOLECULES RICHARD V. BRANCHFLOWER 43
8. CHEMICAL DEPLETION OF GLUTATHIONE IN VIVO JOHN L. PLUMMER, BRIAN R.
SMITH, HELMUT SIES, AND JOHN R. BEND 50
9. DEPLETION OF GLUTATHIONE BY INHIBITION OF BIO- SYNTHESIS OWEN W.
GRIFFITH 59
10. WHOLE-BODY AUTORADIOGRAPHY SVEN ULLBERG AND
BENGT LARSSON 64
B. ORGAN PERFUSION
11. ISOLATED PERFUSED RAT LIVER TECHNIQUE DIRK K. F. MEIJER, KATJA
KEULEMANS, AND GERARD J. MULDER 81
V
IMAGE 2
VI TABLE OF CONTENTS
12. ISOLATED PERFUSED RAT KIDNEY JOHN F. N E W T O N, JR. AND
JERRY B. HOOK 94
13. LUNG PERFUSION TECHNIQUES FOR XENOBIOTIC ME- BRIAN R. S M I TH AND
TABOLISM AND TOXICITY STUDIES J O HN R. B E ND 105
14. VASCULAR AUTOPERFUSION OF RAT SMALL INTESTINE HERBERT G. W I N D M U
E L L ER IN SITU AND ALBERT E. SPAETH 120
C. CELLS
15. PREPARATION OF MAMMALIAN HEPATOCYTES JEFFREY R. FRY 130
16. PREPARATION AND CHARACTERISTICS OF ISOLATED KID- KARI ORMSTAD, S T
EN NEY CELLS ORRENIUS, AND
DEAN P. JONES 137
17. ISOLATION OF PULMONARY CELLS AND USE IN STUDIES THEODORA R. DEVEREUX
OF XENOBIOTIC METABOLISM
18. SEPARATION AND USE OF ENTEROCYTES
19. MAMMALIAN NERVE CELL CULTURE
SECTION II. ENZYME PREPARATIONS
20. 4-NITROPHENOL UDPGLUCURONYLTRANSFERASE BRIAN BURCHELL AND (RAT
LIVER) P H I L IP WEATHERILL 169
21. ESTRONE AND 4-NITROPHENOL UDPGLUCURONYLTRANS- ROBERT H. TUKEY AND
FERASES (RABBIT LIVER) THOMAS R. TEPHLY 177
22. BILIRUBIN UDPGLUCURONYLTRANSFERASE BRIAN BURCHELL 188
23. DISMUTATION OF BILIRUBIN MONOGLUCURONIDE J. R OY C H O W D H U RY
AND
IRWIN M. ARIAS 192
24. ARYL SULFOTRANSFERASES R O N A LD D. SEKURA,
MICHAEL W. D U F F E L, AND WILLIAM B. JAKOBY 197
25. HYDROXYSTEROID SULFOTRANSFERASE E L L EN SUE L Y O N, CAROL J.
MARCUS, J U N - L AN W A N G,
AND WILLIAM B. JAKOBY 206
26. BILE SALT SULFOTRANSFERASE L EE J. C H EN 213
AND JAMES R.
L A W R E N CE M.
W. DLMPFEL
FOUTS
PLNKUS
147
154
162
IMAGE 3
TABLE OF CONTENTS VIL
27. GLUTATHIONE 5-TRANSFERASES (RAT AND HUMAN) WILLIAM H. HABIG AND
WILLIAM B. JAKOBY 218
28. GLUTATHIONE TRANSFERASE (HUMAN PLACENTA) BENGT MANNERVIK AND
CLAES GUTHENBERG 231
29. PURIFICATION OF GLUTATHIONE 5-TRANSFERASES PETER C. SIMONS AND
BY GLUTATHIONE-AFFINITY CHROMATOGRAPHY DAVID L. VANDER JAGT 235
30. Y-GLUTAMYL TRANSPEPTIDASE ALTON MEISTER,
SURESH S. TAETE, AND OWEN W. GRIFFITH 237
31. CYSTEINE CONJUGATE /3-LYASE MITSURU TATEISHI AND
HIROTOSHI SHIMIZU 253
32. THIOL 5-METHYLTRANSFERASE RICHARD A. WEISIGER AND
WILLIAM B. JAKOBY 257
33. ARYLAMINE /V-METHYLTRANSFERASE ELLEN SUE LYON AND
WILLIAM B. JAKOBY 263
34. CATECHOL O-METHYLTRANSFERASE RONALD T. BORCHARDT 267
35. N-ACETYLTRANSFERASE AND ARYLHYDROXAMIC ACID WENDELL W. WEBER AND
ACYLTRANSFERASE CHARLES M. KING 272
36. THIOLTRANSFERASE BENGT MANNERVIK,
KENT AXELSSON, AND
KERSTIN LARSON 281
37. THIOSULFATE: CYANIDE SULFURTRANSFERASE
(RHODANESE) JOHN WESTLEY 285
38. 3-MERCAPTOPYRUVATE SULFURTRANSFERASE REBECCA JARABAK 291
39. GLYOXALASE I (RAT LIVER) BENGT MANNERVIK, ANNE-
CHARLOTTE ARONSSON,
EWA MARMSTAL, AND
GUDRUN TIBBELIN 297
40. BENZOYL-COA : AMINO ACID AND PHENYLACETYL- COA : AMINO ACID
TV-ACYLTRANSFERASES LESLIE T. WEBSTER, JR. 301
41. BILE ACID-COA : AMINO ACID IV-ACYLTRANSFERASE PAUL G. KILLENBERG 308
42. FORMALDEHYDE DEHYDROGENASE LASSE UOTILA AND
MARTTI KOIVUSALO 314
43. S-FORMYLGLUTATHIONE HYDROLASE LASSE UOTILA AND
MARTTI KOIVUSALO 320
IMAGE 4
VLLL TABLE OF CONTENTS
44. GLUTATHIONE PEROXIDASE ALBRECHT WENDEL 325
45. CARBOXYLESTERASES-AMIDASES EBERHARD HEYMANN AND
ROLF MENTLEIN 333
46. MICROSOMAL EPOXIDE HYDROLASE THOMAS M. GUENTHNER,
PHILIP BENTLEY, AND FRANZ OESCH 344
SECTION III. ASSAY SYSTEMS
47. DESIGN OF SOLVENT EXTRACTION METHODS MILTON T. BUSH 353
48. ASSAY OF GLUTATHIONE, GLUTATHIONE DISULFIDE, AND GLUTATHIONE MIXED
DISULFIDES IN BIOLOGICAL THEODORUS P. M. AKERBOOM SAMPLES AND HELMUT
SIES 373
49. ASSAYS FOR UDPGLUCURONYLTRANSFERASE ACTIVITIES G. J. DUTTON, J. E.
A. LEAKEY, AND M. R. POLLARD 383
50. ANALYSIS OF BILIRUBIN CONJUGATES KAREL P. M. HEIRWEGH AND
NORBERT BLANCKAERT 391
51. ASSAYS FOR DIFFERENTIATION OF GLUTATHIONE WILLIAM H. HABIG AND
5-TRANSFERASES WILLIAM B. JAKOBY 398
52. HYDROLYSIS OF AROMATIC AMIDES AS ASSAY FOR EBERHARD HEYMANN,
CARBOXYLESTERASES-AMIDASES ROLF MENTLEIN, AND
HELLA RIX 405
SECTION IV. SYNTHESIS
53. ADENOSINE 3 -PHOSPHATE 5 -PHOSPHOSULFATE RONALD D. SEKURA 413
54. MONO- AND DI-/3-GLUCURONOSIDES OF BILIRUBIN FRANS COMPERNOLLE 416
55. MIXED (UNSYMMETRIC) DISULFIDES: COENZYME A- BENGT MANNERVIK AND
GLUTATHIONE DISULFIDE AS AN EXAMPLE KERSTIN LARSON 420
56. THIOESTERS OF GLUTATHIONE LASSE UOTILA 424
57. COENZYME A THIOESTERS OF BENZOIC, HYDROXY- LESLIE T. WEBSTER, JR.
AND
BENZOIC, PHENYLACETIC, AND BILE ACIDS PAUL G. KILLENBERG 430
AUTHOR INDEX 437
SUBJECT INDEX 457
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institution | BVB |
isbn | 0121819779 |
language | English |
oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-000593699 |
oclc_num | 7777101 |
open_access_boolean | |
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physical | XXII, 476 S. Ill., graph. Darst. |
publishDate | 1981 |
publishDateSearch | 1981 |
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publisher | Acad. Pr. |
record_format | marc |
series | Methods in enzymology |
series2 | Methods in enzymology |
spelling | Detoxication and drug metabolism conjugation and related systems ed. by William B. Jakoby New York u.a. Acad. Pr. 1981 XXII, 476 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Methods in enzymology 77 Drug Metabolism cabt Enzymes Médicaments - Détoxication Médicaments - Métabolisme Drugs Metabolic detoxification Drugs Metabolism Enzymes isolation & purification Metabolic Detoxication, Drug Metabolic conjugation Pharmaceutical Preparations metabolism Stoffwechsel (DE-588)4057699-1 gnd rswk-swf Arzneimittel (DE-588)4003115-9 gnd rswk-swf Arzneimittel (DE-588)4003115-9 s Stoffwechsel (DE-588)4057699-1 s DE-604 Jakoby, William B. Sonstige oth Methods in enzymology 77 (DE-604)BV000000938 77 SWB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=000593699&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
spellingShingle | Detoxication and drug metabolism conjugation and related systems Methods in enzymology Drug Metabolism cabt Enzymes Médicaments - Détoxication Médicaments - Métabolisme Drugs Metabolic detoxification Drugs Metabolism Enzymes isolation & purification Metabolic Detoxication, Drug Metabolic conjugation Pharmaceutical Preparations metabolism Stoffwechsel (DE-588)4057699-1 gnd Arzneimittel (DE-588)4003115-9 gnd |
subject_GND | (DE-588)4057699-1 (DE-588)4003115-9 |
title | Detoxication and drug metabolism conjugation and related systems |
title_auth | Detoxication and drug metabolism conjugation and related systems |
title_exact_search | Detoxication and drug metabolism conjugation and related systems |
title_full | Detoxication and drug metabolism conjugation and related systems ed. by William B. Jakoby |
title_fullStr | Detoxication and drug metabolism conjugation and related systems ed. by William B. Jakoby |
title_full_unstemmed | Detoxication and drug metabolism conjugation and related systems ed. by William B. Jakoby |
title_short | Detoxication and drug metabolism |
title_sort | detoxication and drug metabolism conjugation and related systems |
title_sub | conjugation and related systems |
topic | Drug Metabolism cabt Enzymes Médicaments - Détoxication Médicaments - Métabolisme Drugs Metabolic detoxification Drugs Metabolism Enzymes isolation & purification Metabolic Detoxication, Drug Metabolic conjugation Pharmaceutical Preparations metabolism Stoffwechsel (DE-588)4057699-1 gnd Arzneimittel (DE-588)4003115-9 gnd |
topic_facet | Drug Metabolism Enzymes Médicaments - Détoxication Médicaments - Métabolisme Drugs Metabolic detoxification Drugs Metabolism Enzymes isolation & purification Metabolic Detoxication, Drug Metabolic conjugation Pharmaceutical Preparations metabolism Stoffwechsel Arzneimittel |
url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=000593699&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
volume_link | (DE-604)BV000000938 |
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