Cell kinetic modelling and the chemotherapy of cancer:
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Berlin u.a.
Springer
1988
|
| Schriftenreihe: | Lecture notes in biomathematics
75 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | VIII, 157 S. graph. Darst. |
| ISBN: | 3540501533 0387501533 |
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Datensatz im Suchindex
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| adam_text |
LECTURE NOTES IN BIOMATHEMATICS MANAGING EDITOR: S. LEVIN 75 HELMUT
KNOLLE CELL KINETIC MODELLING AND THE CHEMOTHERAPY OF CANCER
SPRINGER-VERLAG BERLIN HEIDELBERG NEW YORK LONDON PARIS TOKYO CONTENTS
PAGE PREFACE IH CHAPTER I . MATHEMATICAL MODELS OF CELL POPULATIONS 1.
PROLIFERATION AND DIFFERENTIATION OF CELLS 1 2. THE CELL CYCLE 6 3. THE
SIMPLE MODEL OF TUMOR GROWTH 8 4. THE EXTENDED MODEL OF TUMOR GROWTH 14
5. CELL AGE DISTRIBUTION AND PHASE INDICES 17 6. THE GENERAL MODEL WITH
DISTRIBUTED CYCLE TIME 25 7. THE KENDAL1-TAKAHASHI MODEL 37 CHAPTER II .
DETERMINATION OF CELL KINETIC PARAMETERS INTRODUCTION: CELL KINETIC
EXPERIMENTS 46 1. PULSE LABELLING 48 2. CONTINUOUS LABELLING 54 3.
METAPHASE ARREST 59 4. CONTINUOUS LABELLING WITH METAPHASE ARREST 63 5.
FRACTIONS OF LABELLED MITOSES (FLM) 65 6. DOUBLE LABELLING 71 7. DOUBLE
LABELLING AND FLM 78 8. WHICH EXPERIMENTS ARE TO BE CHOSEN? 80 VIII
CHAPTER III . CELL KINETICS AND CANCER THERAPY INTRODUCTION 84 1. THE
SURVIVING FRACTION AFTER A SINGLE DOSE 88 2. PHASE-SPECIFIC CELL KILL 93
3. BLOCK OF THE CELL CYCLE 98 4. RECRUITMENT OF RESTING CELLS 109 5. A
COMPLEX MATHEMATICAL MODEL AND COMPUTER PROGRAMS 113 6. IMPLICATIONS FOR
DRUG TESTING 122 7. POTENTIAL IMPLICATIONS FOR THERAPY 124 APPENDIX 1.
LIMIT THEOREMS FOR MATRIX MODELS, 132 2. A MODEL WITH PERIODIC
PARAMETERS 140 3. PHARMACOKINETICS AND THE DOSE-EFFECT RELATION 144 LIST
OF SYMBOLS 149 REFERENCES 151 SUBJECT INDEX 156 |
| any_adam_object | 1 |
| author | Knolle, Helmut |
| author_facet | Knolle, Helmut |
| author_role | aut |
| author_sort | Knolle, Helmut |
| author_variant | h k hk |
| building | Verbundindex |
| bvnumber | BV000849954 |
| callnumber-first | R - Medicine |
| callnumber-label | RC271 |
| callnumber-raw | RC271.C5 |
| callnumber-search | RC271.C5 |
| callnumber-sort | RC 3271 C5 |
| callnumber-subject | RC - Internal Medicine |
| classification_rvk | SI 840 |
| classification_tum | BIO 200f BIO 105f MED 970f |
| ctrlnum | (OCoLC)18351709 (DE-599)BVBBV000849954 |
| dewey-full | 616.99/4061 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 616 - Diseases |
| dewey-raw | 616.99/4061 |
| dewey-search | 616.99/4061 |
| dewey-sort | 3616.99 44061 |
| dewey-tens | 610 - Medicine and health |
| discipline | Biologie Mathematik Medizin |
| format | Book |
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| spelling | Knolle, Helmut Verfasser aut Cell kinetic modelling and the chemotherapy of cancer Berlin u.a. Springer 1988 VIII, 157 S. graph. Darst. txt rdacontent n rdamedia nc rdacarrier Lecture notes in biomathematics 75 Cancer - Chimiothérapie - Modèles mathématiques Cellules cancéreuses - Croissance - Modèles mathématiques Cytocinèse - Modèles mathématiques Mathematisches Modell Cancer cells Growth Mathematical models Cancer Chemotherapy Mathematical models Cell Cycle Cytokinesis Mathematical models Models, Biological Neoplasms drug therapy Cytostatikum (DE-588)4068347-3 gnd rswk-swf Wachstum (DE-588)4064115-6 gnd rswk-swf Krebszelle (DE-588)4128704-6 gnd rswk-swf Wirkung (DE-588)4190021-2 gnd rswk-swf Mathematisches Modell (DE-588)4114528-8 gnd rswk-swf Krebs Medizin (DE-588)4073781-0 gnd rswk-swf Proliferation (DE-588)4047461-6 gnd rswk-swf Statistisches Modell (DE-588)4121722-6 gnd rswk-swf Chemotherapie (DE-588)4127083-6 gnd rswk-swf Proliferation (DE-588)4047461-6 s Mathematisches Modell (DE-588)4114528-8 s DE-604 Cytostatikum (DE-588)4068347-3 s Wirkung (DE-588)4190021-2 s Krebs Medizin (DE-588)4073781-0 s Chemotherapie (DE-588)4127083-6 s Statistisches Modell (DE-588)4121722-6 s Krebszelle (DE-588)4128704-6 s Wachstum (DE-588)4064115-6 s Lecture notes in biomathematics 75 (DE-604)BV005875746 75 GBV Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=000533508&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Knolle, Helmut Cell kinetic modelling and the chemotherapy of cancer Lecture notes in biomathematics Cancer - Chimiothérapie - Modèles mathématiques Cellules cancéreuses - Croissance - Modèles mathématiques Cytocinèse - Modèles mathématiques Mathematisches Modell Cancer cells Growth Mathematical models Cancer Chemotherapy Mathematical models Cell Cycle Cytokinesis Mathematical models Models, Biological Neoplasms drug therapy Cytostatikum (DE-588)4068347-3 gnd Wachstum (DE-588)4064115-6 gnd Krebszelle (DE-588)4128704-6 gnd Wirkung (DE-588)4190021-2 gnd Mathematisches Modell (DE-588)4114528-8 gnd Krebs Medizin (DE-588)4073781-0 gnd Proliferation (DE-588)4047461-6 gnd Statistisches Modell (DE-588)4121722-6 gnd Chemotherapie (DE-588)4127083-6 gnd |
| subject_GND | (DE-588)4068347-3 (DE-588)4064115-6 (DE-588)4128704-6 (DE-588)4190021-2 (DE-588)4114528-8 (DE-588)4073781-0 (DE-588)4047461-6 (DE-588)4121722-6 (DE-588)4127083-6 |
| title | Cell kinetic modelling and the chemotherapy of cancer |
| title_auth | Cell kinetic modelling and the chemotherapy of cancer |
| title_exact_search | Cell kinetic modelling and the chemotherapy of cancer |
| title_full | Cell kinetic modelling and the chemotherapy of cancer |
| title_fullStr | Cell kinetic modelling and the chemotherapy of cancer |
| title_full_unstemmed | Cell kinetic modelling and the chemotherapy of cancer |
| title_short | Cell kinetic modelling and the chemotherapy of cancer |
| title_sort | cell kinetic modelling and the chemotherapy of cancer |
| topic | Cancer - Chimiothérapie - Modèles mathématiques Cellules cancéreuses - Croissance - Modèles mathématiques Cytocinèse - Modèles mathématiques Mathematisches Modell Cancer cells Growth Mathematical models Cancer Chemotherapy Mathematical models Cell Cycle Cytokinesis Mathematical models Models, Biological Neoplasms drug therapy Cytostatikum (DE-588)4068347-3 gnd Wachstum (DE-588)4064115-6 gnd Krebszelle (DE-588)4128704-6 gnd Wirkung (DE-588)4190021-2 gnd Mathematisches Modell (DE-588)4114528-8 gnd Krebs Medizin (DE-588)4073781-0 gnd Proliferation (DE-588)4047461-6 gnd Statistisches Modell (DE-588)4121722-6 gnd Chemotherapie (DE-588)4127083-6 gnd |
| topic_facet | Cancer - Chimiothérapie - Modèles mathématiques Cellules cancéreuses - Croissance - Modèles mathématiques Cytocinèse - Modèles mathématiques Mathematisches Modell Cancer cells Growth Mathematical models Cancer Chemotherapy Mathematical models Cell Cycle Cytokinesis Mathematical models Models, Biological Neoplasms drug therapy Cytostatikum Wachstum Krebszelle Wirkung Krebs Medizin Proliferation Statistisches Modell Chemotherapie |
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