New frontiers in the study of gene functions:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
New York u.a.
Plenum Pr.
1987
|
| Schriftenreihe: | New horizons in therapeutics
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XVI, 202 S. |
| ISBN: | 0306425025 |
Internformat
MARC
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| 650 | 4 | |a Expressivité génétique | |
| 650 | 4 | |a Génie génétique | |
| 650 | 4 | |a Génétique microbienne | |
| 650 | 4 | |a Régulation génétique | |
| 650 | 4 | |a Gene expression | |
| 650 | 4 | |a Genetic Engineering | |
| 650 | 4 | |a Genetic engineering | |
| 650 | 4 | |a Genetic regulation | |
| 650 | 4 | |a Microbial genetics | |
| 650 | 4 | |a Molecular Biology | |
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Datensatz im Suchindex
| _version_ | 1804115114541973504 |
|---|---|
| adam_text | New Frontiers
in the Study of
Gene Functions
Edited by
GEORGE POSTE and
STANLEY T CROOKE
Smith Kline amp; French Laboratories
Philadelphia, Pennsylvania
PLENUM PRESS • NEW YORK AND LONDON
Contents
Chapter 1
The Role of Cis- and Trans-Acting Functions in Simian Virus 40
Gene Regulation
George Khoury, Kamel Khalili, Janet Duvall,
and John Brady
1 Introduction 1
2 Early Viral Transcriptional Program 3
3 Late Viral Transcriptional Program 10
4 Discussion 14
References 17
Chapter 2
Regulation of the Heat-Shock Response in Escherichia coli
Carol Gross, Deborah Cowing, James Erickson,
Alan Grossman, David Straus, William Walter,
and Yan-Ning Zhou
1 Introduction 21
2 Transcription of the Heat-Shock Genes 23
3 Regulation of rpoH and a32 24
4 Function of the Heat-Shock Proteins 27
5 Summary 30
References 30
Chapter 3 :
Negative Control of DNA Replication Revealed in Composite
Simian Virus 40-Bovine Papillomavirus Plasmids
James M Roberts and Harold Weintraub
xii Contents
1 Overview 33
2 Introduction 34
3 Results 36
3 1 Construction of Composite Simian Virus 40-Bovine
Papillomavirus Replicons 36
3 2 Construction of Permanent Cell Lines Containing
Simian Virus 40-Bovine Papillomavirus Composite
Plasmids 37
4 Discussion 41
4 1 Negative Control of DNA Replication 41
4 2 Mechanisms of Replication Control 43
4 3 Gene Amplification 45
4 4 Relation to the Inactive Mating-Type Cassettes
in Yeast 46
References 47
Chapter 4
DNA Supercoiling as a Regulator of Bacterial Gene Expression
Martin Gettert and Rolf Menzel
1 Introduction • 51
2 Results and Discussion 54
References 58
Chapter 5
Retrotransposition in Yeast
Gerald R Fink
1 Introduction 61
2 Experiments 61
3 Speculation 66
References 70
r
Chapter 6
Comparative Genetic Analysis of Homeobox Genes in Mouse
and Man
Frank H Ruddle, Charles P Hart, Mark Rabin,
Anne Ferguson-Smith, and Dimitrina Pravtcheva
Contents xiii
1 Introduction 73
2 Murine Homeobox Genes 74
3 Human Homeobox Genes 75
4 Comparative Genetic Relationships between Species 75
5 Comparative Genetic Relationships within Species 80
6 Possible Functional Relationships between Homeobox Loci
and Linked Genes 81
6 1 Mouse Hox-1, Chromosome 6 81
6 2 Mouse Hox-2, Chromosome 11 81
6 3 Mouse Hox-3, Chromosome 15 82
6 4 Human Hox-1, Chromosome 7 82
6 5 Human Hox-2, Chromosome 17 82
7 Discussion 83
References 84
Chapter 7
Eukaryotic Transcriptional Specificity Conferred by DNA-
Binding Proteins
James T Kadonaga, Michael R Briggs, and Robert Tjian
1 Introduction 87
2 Results and Discussion 89
2 1 Cis and Trans Regulatory Components of the Simian
Virus 40 Promoter 89
2 2 Role of Spl in Other Viral and Cellular Promoters 92
23A Consensus Spl Recognition Sequence 95
3 Concluding Remarks 95
References 97
Chapter 8
Chromatin Structure Near an Expressed Gene
Gary Felsenfeld, Beverly M Emerson, P David Jackson,
Catherine D Lewis, Joanne E Hesse, Michael R Lieber,
and Joanne M Nickol
1 Introduction 99
2 Results « 101
3 Discussion 106
References 108
xvi Contents
/
2 5 Infection by AIDS Is Not Restricted to T Lymphocytes 169
2 6 T4 Serves as a Receptor for AIDS Virus 171
2 7 Receptor-Mediated Endocytosis: A Possible Mechanism
of Viral Entry 171
References 173
Chapter 14
Identifying the Determinants of Protein Function and Stability
Robert T Sauer, Hillary C M Nelson, Michael H Hecht,
and Andrew Pakula
1 Introduction 177
2 Repressor and Cro Background 178
2 1 Protein Structures 178
2 2 Complexes with Operator DNA 178
3 Isolation of Phenotypically Defective Mutants 179
4 Structural Distribution of Mutant Sites 183
5 Why Are Mutant Proteins Nonfunctional? 184
5 1 Contribution of Proteolysis to Mutant Phenotypes 185
5 2 Mutations That Affect Protein Stability 186
5 3 DNA-Binding Mutations 188
6 Phenotypic Reversion 189
6 1 Same-Site Revertants 190
6 2 Second-Site Revertants 191
6 3 Suppression Occurs by Enhancement of Activity 192
7 Summary 195
References 196
Index 199
|
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| series2 | New horizons in therapeutics |
| spelling | New frontiers in the study of gene functions ed. by George Poste ... New York u.a. Plenum Pr. 1987 XVI, 202 S. txt rdacontent n rdamedia nc rdacarrier New horizons in therapeutics Expressivité génétique Génie génétique Génétique microbienne Régulation génétique Gene expression Genetic Engineering Genetic engineering Genetic regulation Microbial genetics Molecular Biology Genregulation (DE-588)4122166-7 gnd rswk-swf Genexpression (DE-588)4020136-3 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Genexpression (DE-588)4020136-3 s DE-604 Genregulation (DE-588)4122166-7 s Poste, George Sonstige oth HEBIS Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=000415787&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | New frontiers in the study of gene functions Expressivité génétique Génie génétique Génétique microbienne Régulation génétique Gene expression Genetic Engineering Genetic engineering Genetic regulation Microbial genetics Molecular Biology Genregulation (DE-588)4122166-7 gnd Genexpression (DE-588)4020136-3 gnd |
| subject_GND | (DE-588)4122166-7 (DE-588)4020136-3 (DE-588)4143413-4 |
| title | New frontiers in the study of gene functions |
| title_auth | New frontiers in the study of gene functions |
| title_exact_search | New frontiers in the study of gene functions |
| title_full | New frontiers in the study of gene functions ed. by George Poste ... |
| title_fullStr | New frontiers in the study of gene functions ed. by George Poste ... |
| title_full_unstemmed | New frontiers in the study of gene functions ed. by George Poste ... |
| title_short | New frontiers in the study of gene functions |
| title_sort | new frontiers in the study of gene functions |
| topic | Expressivité génétique Génie génétique Génétique microbienne Régulation génétique Gene expression Genetic Engineering Genetic engineering Genetic regulation Microbial genetics Molecular Biology Genregulation (DE-588)4122166-7 gnd Genexpression (DE-588)4020136-3 gnd |
| topic_facet | Expressivité génétique Génie génétique Génétique microbienne Régulation génétique Gene expression Genetic Engineering Genetic engineering Genetic regulation Microbial genetics Molecular Biology Genregulation Genexpression Aufsatzsammlung |
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