Animals and alternatives in toxicity testing: [proceedings of a meeting held at the Royal Society of London on 1 - 3 Nov. 1982 to discuss the report of the FRAME Toxicity Committee]
Saved in:
| Format: | Book |
|---|---|
| Language: | English |
| Published: |
London [u.a.]
Acad. Press
1983
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| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Physical Description: | VI, 550 S. |
| ISBN: | 0120774801 |
Staff View
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Record in the Search Index
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| adam_text | O ANIMALS AND ALTERNATIVES IN TOXICITY TESTING EDITORS MICHAEL BALLS
ROSEMARYJ. RIDDELL ALASTAIR N. WORDEN 1983 E; »CI. . FS- ACADEMIC
PRESS A SUBSIDIARY OF HARCOURT BRACE JOVANOVICH, PUBLISHERS LONDON NEW
YORK PARIS SAN DIEGO SAN FRANCISCO SAO PAULO SYDNEY TOKYO TORONTO
CONTENTS CONTRIBUTORS I PREFACE V ACUTE TOXICITY ACUTE TOXICITY TESTING
V.K.H. BROWN 1 SHORT-TERM TESTING IN DRUG DEVELOPMENT J.S.L. FOWLER 16
ALTERNATIVES IN ACUTE TOXICITY TESTING M.C. TATTERSALL 23 GENERAL
DISCUSSION ROY GOULDING (RAPPORTEUR) 26 PHARMACOKINETICS APPLICATION OF
PHARMACOKINETICS J.W. BRIDGES, L.F. CHASSEAUD, G.M. COHEN & C.H. WALKER
31 IMMUNOLOGY IN SAFETY EVALUATION KLARA MILLER 67 PHARMACOKINETICS AND
PESTICIDES G.T. BROOKS 71 GENERAL DISCUSSION C.H. WALKER (RAPPORTEUR) 75
LONG-TERM TOXICITY LONG-TERM TOXICITY RALPH HEYWOOD 79 IS THERE AN
ALTERNATIVE? S.R. WALKER 93 REPEAT-DOSE LONG-TERM TOXICITY STUDIES J.P.
GRIFFIN 98 GENERAL DISCUSSION A.N. WORDEN (RAPPORTEUR) 104
CARCINOGENICITY CARCINOGENICITY I.F.H. PURCHASE 109 CARCINOGENICITY
TESTING F.J.C. ROE 127 NEW APPROACHES J.W. WEISBURGER 131 GENERAL
DISCUSSION PETER KNOX (RAPPORTEUR) 135 MATHEMATICAL MODELLING
MATHEMATICAL MODELLING M.S. TUTE 137 STRUCTURE-TOXICITY STUDIES DAVID
BAWDEN 151 MATHEMATICAL MODELS IN PHARMACOTOXICITY E.R. CARSON 154
QUANTITATIVE USE OF STRUCTURAL DESIGNS J.C. DEARDEN 160 GENERAL
DISCUSSION DAVID MACHIN (RAPPORTEUR) 165 DESIGN OF EXPERIMENTS
STATISTICAL CONTRIBUTIONS TO EXPERIMENTAL DESIGN G.F. HEALEY 167
STATISTICS AND THE OBJECTIVES OF FRAME D.O. CHANTER 188 DESIGN AND
ANALYSIS OF CARCINOGENICITY STUDIES P.N. LEE 191 GENERAL DISCUSSION
DAVID MACHIN (RAPPORTEUR) 194 REPRODUCTIVE TOXICITY REPRODUCTIVE
TOXICITY C.L. BERRY 197 IN VITRO REPRODUCTIVE TOXICITY STUDIES KEITH
SNELL 207 PROBLEMS IN CURRENT REPRODUCTIVE TOXICITY TESTING N.A. BROWN
214 ALTERNATIVE METHODS A.K. PALMER 218 HAZARDS TO DEVELOPMENT RUTH
CLAYTON 221 GENERAL DISCUSSION A.N. WORDEN (RAPPORTEUR) 226
NEUROTOXICITY NEUROTOXICITY A.J. DEWAR 229 NEUROTOXICITY TESTING: SOME
OBSERVATIONS H.W. READING 284 THE INTEGRATIVE APPROACH ROBERT HESS, G.
KRINKE & J. SCHAEPPI 288 HUMAN ACCIDENTS NIGEL LEGG 294 GENERAL
DISCUSSION A.N. WORDEN (RAPPORTEUR) 296 INHALATION TOXICITY INHALATION
TOXICITY D.G. CLARK 299 INHALATION TOXICOLOGY R.C. BROWN & ALAN POOLE
300 RECOMMENDATIONS D.G. CLARK & R.C. BROWN 309 GENERAL DISCUSSION A.N.
WORDEN (RAPPORTEUR) 311 DERMAL TOXICITY TESTING FOR CUTANEOUS TOXICITY
RONALD MARKS 313 SKIN PHOTOTOXICITY IN MAN A.R. YOUNG 327 DERMAL
TOXICITY J.M. FACEINI & J.P. GUILLOT 329 GENERAL DISCUSSION N.J. VAN
ABBE (RAPPORTEUR) 335 OCULAR TOXICITY EYE IRRITANCY TESTING D.W.
SWANSTON 337 IN VITRO STUDIES ON OCULAR IRRITANCY M.C. SCAIFE 367 AN
ISOLATED RABBIT EYE TECHNIQUE MICHAEL YORK 369 DOSAGE-VOLUME, SAMPLE
SIZE AND PREDICTABILITY S.J. WILLIAMS 371 GENERAL DISCUSSION N.J. VAN
ABBE (RAPPORTEUR) 378 ADDENDUM ON DERMAL AND OCULAR TOXICITY N.J. VAN
ABBE 379 GENOTOXICITY SHORT-TERM TESTS FOR GENOTOXICITY B.J. DEAN &
PETER HODGES 381 CYTOGENETIC MONITORING OF HUMAN POPULATIONS D.J.
KIRKLAND 409 SOME COMMENTS ON GENOTOXICITY TESTING ERIC LONGSTAFF 414 IN
VITRO ASSAYS J.M. PARRY 419 GENERAL DISCUSSION PETER HODGES (RAPPORTEUR)
426 HUMAN STUDIES EVALUATION OF TOXICITY IN MAN N.W. SHEPHARD 429 DRUG
AND CHEMICAL TOXICITY IN HUMANS P.N. BENNETT 435 LESSONS LEARNED W.H.W.
INMAN 439 GENERAL DISCUSSION PAUL TURNER (RAPPORTEUR) 442 REGULATIONS
REGULATORY ASPECTS DENNIS V.W. PARKE 445 THE NEED FOR FLEXIBILITY ANDREW
COCKBURN 457 CONSULTATION WITH THE REGULATORY AUTHORITIES A.N. WORDEN
459 IMPROVING LEGISLATION R.S. VINE 462 GENERAL DISCUSSION D.M. CONNING
(RAPPORTEUR) 467 DEVELOPMENT OF ALTERNATIVES THE FRAME RESEARCH
PROGRAMME MICHAEL BALLS 471 THE JOHNS HOPKINS CENTER A.M. GOLDBERG 476
DISCUSSIONS ROUND TABLE DISCUSSION K.J. OBRINK (CHAIRMAN) 481 SUMMING-UP
LEON GOLBERG 493 APPENDIX REPORT OF THE FRAME TOXICITY COMMITTEE 501
SUBJECT INDEX 541
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| genre_facet | Konferenzschrift 1982 London |
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| indexdate | 2024-07-09T15:13:13Z |
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| isbn | 0120774801 |
| language | English |
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| physical | VI, 550 S. |
| publishDate | 1983 |
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| spelling | Animals and alternatives in toxicity testing [proceedings of a meeting held at the Royal Society of London on 1 - 3 Nov. 1982 to discuss the report of the FRAME Toxicity Committee] ed. Michael Balls ... London [u.a.] Acad. Press 1983 VI, 550 S. txt rdacontent n rdamedia nc rdacarrier Animal Testing Alternatives cabt Toxicity cabt conferences cabt Tierversuch (DE-588)4060137-7 gnd rswk-swf Toxizitätstest (DE-588)4060540-1 gnd rswk-swf Alternative (DE-588)4138905-0 gnd rswk-swf (DE-588)1071861417 Konferenzschrift 1982 London gnd-content Toxizitätstest (DE-588)4060540-1 s Tierversuch (DE-588)4060137-7 s Alternative (DE-588)4138905-0 s DE-604 Balls, Michael Sonstige oth Fund for the Replacement of Animals in Medical Experiments Toxicity Committee Sonstige (DE-588)1705209-9 oth GBV Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=000239866&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Animals and alternatives in toxicity testing [proceedings of a meeting held at the Royal Society of London on 1 - 3 Nov. 1982 to discuss the report of the FRAME Toxicity Committee] Animal Testing Alternatives cabt Toxicity cabt conferences cabt Tierversuch (DE-588)4060137-7 gnd Toxizitätstest (DE-588)4060540-1 gnd Alternative (DE-588)4138905-0 gnd |
| subject_GND | (DE-588)4060137-7 (DE-588)4060540-1 (DE-588)4138905-0 (DE-588)1071861417 |
| title | Animals and alternatives in toxicity testing [proceedings of a meeting held at the Royal Society of London on 1 - 3 Nov. 1982 to discuss the report of the FRAME Toxicity Committee] |
| title_auth | Animals and alternatives in toxicity testing [proceedings of a meeting held at the Royal Society of London on 1 - 3 Nov. 1982 to discuss the report of the FRAME Toxicity Committee] |
| title_exact_search | Animals and alternatives in toxicity testing [proceedings of a meeting held at the Royal Society of London on 1 - 3 Nov. 1982 to discuss the report of the FRAME Toxicity Committee] |
| title_full | Animals and alternatives in toxicity testing [proceedings of a meeting held at the Royal Society of London on 1 - 3 Nov. 1982 to discuss the report of the FRAME Toxicity Committee] ed. Michael Balls ... |
| title_fullStr | Animals and alternatives in toxicity testing [proceedings of a meeting held at the Royal Society of London on 1 - 3 Nov. 1982 to discuss the report of the FRAME Toxicity Committee] ed. Michael Balls ... |
| title_full_unstemmed | Animals and alternatives in toxicity testing [proceedings of a meeting held at the Royal Society of London on 1 - 3 Nov. 1982 to discuss the report of the FRAME Toxicity Committee] ed. Michael Balls ... |
| title_short | Animals and alternatives in toxicity testing |
| title_sort | animals and alternatives in toxicity testing proceedings of a meeting held at the royal society of london on 1 3 nov 1982 to discuss the report of the frame toxicity committee |
| title_sub | [proceedings of a meeting held at the Royal Society of London on 1 - 3 Nov. 1982 to discuss the report of the FRAME Toxicity Committee] |
| topic | Animal Testing Alternatives cabt Toxicity cabt conferences cabt Tierversuch (DE-588)4060137-7 gnd Toxizitätstest (DE-588)4060540-1 gnd Alternative (DE-588)4138905-0 gnd |
| topic_facet | Animal Testing Alternatives Toxicity conferences Tierversuch Toxizitätstest Alternative Konferenzschrift 1982 London |
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