Verfügbarkeit: Animals and alternatives in toxicity testing

Animals and alternatives in toxicity testing: [proceedings of a meeting held at the Royal Society of London on 1 - 3 Nov. 1982 to discuss the report of the FRAME Toxicity Committee]

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Bibliographische Detailangaben
Format:	Buch
Sprache:	English
Veröffentlicht:	London [u.a.] Acad. Press 1983
Schlagworte:	Animal Testing Alternatives Toxicity conferences Tierversuch Toxizitätstest Alternative Konferenzschrift > 1982 > London
Online-Zugang:	Inhaltsverzeichnis
Beschreibung:	VI, 550 S.
ISBN:	0120774801

Internformat

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Datensatz im Suchindex

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adam_text	O ANIMALS AND ALTERNATIVES IN TOXICITY TESTING EDITORS MICHAEL BALLS ROSEMARYJ. RIDDELL ALASTAIR N. WORDEN 1983 E; »CI. . FS- ACADEMIC PRESS A SUBSIDIARY OF HARCOURT BRACE JOVANOVICH, PUBLISHERS LONDON NEW YORK PARIS SAN DIEGO SAN FRANCISCO SAO PAULO SYDNEY TOKYO TORONTO CONTENTS CONTRIBUTORS I PREFACE V ACUTE TOXICITY ACUTE TOXICITY TESTING V.K.H. BROWN 1 SHORT-TERM TESTING IN DRUG DEVELOPMENT J.S.L. FOWLER 16 ALTERNATIVES IN ACUTE TOXICITY TESTING M.C. TATTERSALL 23 GENERAL DISCUSSION ROY GOULDING (RAPPORTEUR) 26 PHARMACOKINETICS APPLICATION OF PHARMACOKINETICS J.W. BRIDGES, L.F. CHASSEAUD, G.M. COHEN & C.H. WALKER 31 IMMUNOLOGY IN SAFETY EVALUATION KLARA MILLER 67 PHARMACOKINETICS AND PESTICIDES G.T. BROOKS 71 GENERAL DISCUSSION C.H. WALKER (RAPPORTEUR) 75 LONG-TERM TOXICITY LONG-TERM TOXICITY RALPH HEYWOOD 79 IS THERE AN ALTERNATIVE? S.R. WALKER 93 REPEAT-DOSE LONG-TERM TOXICITY STUDIES J.P. GRIFFIN 98 GENERAL DISCUSSION A.N. WORDEN (RAPPORTEUR) 104 CARCINOGENICITY CARCINOGENICITY I.F.H. PURCHASE 109 CARCINOGENICITY TESTING F.J.C. ROE 127 NEW APPROACHES J.W. WEISBURGER 131 GENERAL DISCUSSION PETER KNOX (RAPPORTEUR) 135 MATHEMATICAL MODELLING MATHEMATICAL MODELLING M.S. TUTE 137 STRUCTURE-TOXICITY STUDIES DAVID BAWDEN 151 MATHEMATICAL MODELS IN PHARMACOTOXICITY E.R. CARSON 154 QUANTITATIVE USE OF STRUCTURAL DESIGNS J.C. DEARDEN 160 GENERAL DISCUSSION DAVID MACHIN (RAPPORTEUR) 165 DESIGN OF EXPERIMENTS STATISTICAL CONTRIBUTIONS TO EXPERIMENTAL DESIGN G.F. HEALEY 167 STATISTICS AND THE OBJECTIVES OF FRAME D.O. CHANTER 188 DESIGN AND ANALYSIS OF CARCINOGENICITY STUDIES P.N. LEE 191 GENERAL DISCUSSION DAVID MACHIN (RAPPORTEUR) 194 REPRODUCTIVE TOXICITY REPRODUCTIVE TOXICITY C.L. BERRY 197 IN VITRO REPRODUCTIVE TOXICITY STUDIES KEITH SNELL 207 PROBLEMS IN CURRENT REPRODUCTIVE TOXICITY TESTING N.A. BROWN 214 ALTERNATIVE METHODS A.K. PALMER 218 HAZARDS TO DEVELOPMENT RUTH CLAYTON 221 GENERAL DISCUSSION A.N. WORDEN (RAPPORTEUR) 226 NEUROTOXICITY NEUROTOXICITY A.J. DEWAR 229 NEUROTOXICITY TESTING: SOME OBSERVATIONS H.W. READING 284 THE INTEGRATIVE APPROACH ROBERT HESS, G. KRINKE & J. SCHAEPPI 288 HUMAN ACCIDENTS NIGEL LEGG 294 GENERAL DISCUSSION A.N. WORDEN (RAPPORTEUR) 296 INHALATION TOXICITY INHALATION TOXICITY D.G. CLARK 299 INHALATION TOXICOLOGY R.C. BROWN & ALAN POOLE 300 RECOMMENDATIONS D.G. CLARK & R.C. BROWN 309 GENERAL DISCUSSION A.N. WORDEN (RAPPORTEUR) 311 DERMAL TOXICITY TESTING FOR CUTANEOUS TOXICITY RONALD MARKS 313 SKIN PHOTOTOXICITY IN MAN A.R. YOUNG 327 DERMAL TOXICITY J.M. FACEINI & J.P. GUILLOT 329 GENERAL DISCUSSION N.J. VAN ABBE (RAPPORTEUR) 335 OCULAR TOXICITY EYE IRRITANCY TESTING D.W. SWANSTON 337 IN VITRO STUDIES ON OCULAR IRRITANCY M.C. SCAIFE 367 AN ISOLATED RABBIT EYE TECHNIQUE MICHAEL YORK 369 DOSAGE-VOLUME, SAMPLE SIZE AND PREDICTABILITY S.J. WILLIAMS 371 GENERAL DISCUSSION N.J. VAN ABBE (RAPPORTEUR) 378 ADDENDUM ON DERMAL AND OCULAR TOXICITY N.J. VAN ABBE 379 GENOTOXICITY SHORT-TERM TESTS FOR GENOTOXICITY B.J. DEAN & PETER HODGES 381 CYTOGENETIC MONITORING OF HUMAN POPULATIONS D.J. KIRKLAND 409 SOME COMMENTS ON GENOTOXICITY TESTING ERIC LONGSTAFF 414 IN VITRO ASSAYS J.M. PARRY 419 GENERAL DISCUSSION PETER HODGES (RAPPORTEUR) 426 HUMAN STUDIES EVALUATION OF TOXICITY IN MAN N.W. SHEPHARD 429 DRUG AND CHEMICAL TOXICITY IN HUMANS P.N. BENNETT 435 LESSONS LEARNED W.H.W. INMAN 439 GENERAL DISCUSSION PAUL TURNER (RAPPORTEUR) 442 REGULATIONS REGULATORY ASPECTS DENNIS V.W. PARKE 445 THE NEED FOR FLEXIBILITY ANDREW COCKBURN 457 CONSULTATION WITH THE REGULATORY AUTHORITIES A.N. WORDEN 459 IMPROVING LEGISLATION R.S. VINE 462 GENERAL DISCUSSION D.M. CONNING (RAPPORTEUR) 467 DEVELOPMENT OF ALTERNATIVES THE FRAME RESEARCH PROGRAMME MICHAEL BALLS 471 THE JOHNS HOPKINS CENTER A.M. GOLDBERG 476 DISCUSSIONS ROUND TABLE DISCUSSION K.J. OBRINK (CHAIRMAN) 481 SUMMING-UP LEON GOLBERG 493 APPENDIX REPORT OF THE FRAME TOXICITY COMMITTEE 501 SUBJECT INDEX 541
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spelling	Animals and alternatives in toxicity testing [proceedings of a meeting held at the Royal Society of London on 1 - 3 Nov. 1982 to discuss the report of the FRAME Toxicity Committee] ed. Michael Balls ... London [u.a.] Acad. Press 1983 VI, 550 S. txt rdacontent n rdamedia nc rdacarrier Animal Testing Alternatives cabt Toxicity cabt conferences cabt Tierversuch (DE-588)4060137-7 gnd rswk-swf Toxizitätstest (DE-588)4060540-1 gnd rswk-swf Alternative (DE-588)4138905-0 gnd rswk-swf (DE-588)1071861417 Konferenzschrift 1982 London gnd-content Toxizitätstest (DE-588)4060540-1 s Tierversuch (DE-588)4060137-7 s Alternative (DE-588)4138905-0 s DE-604 Balls, Michael Sonstige oth Fund for the Replacement of Animals in Medical Experiments Toxicity Committee Sonstige (DE-588)1705209-9 oth GBV Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=000239866&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis
spellingShingle	Animals and alternatives in toxicity testing [proceedings of a meeting held at the Royal Society of London on 1 - 3 Nov. 1982 to discuss the report of the FRAME Toxicity Committee] Animal Testing Alternatives cabt Toxicity cabt conferences cabt Tierversuch (DE-588)4060137-7 gnd Toxizitätstest (DE-588)4060540-1 gnd Alternative (DE-588)4138905-0 gnd
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title	Animals and alternatives in toxicity testing [proceedings of a meeting held at the Royal Society of London on 1 - 3 Nov. 1982 to discuss the report of the FRAME Toxicity Committee]
title_auth	Animals and alternatives in toxicity testing [proceedings of a meeting held at the Royal Society of London on 1 - 3 Nov. 1982 to discuss the report of the FRAME Toxicity Committee]
title_exact_search	Animals and alternatives in toxicity testing [proceedings of a meeting held at the Royal Society of London on 1 - 3 Nov. 1982 to discuss the report of the FRAME Toxicity Committee]
title_full	Animals and alternatives in toxicity testing [proceedings of a meeting held at the Royal Society of London on 1 - 3 Nov. 1982 to discuss the report of the FRAME Toxicity Committee] ed. Michael Balls ...
title_fullStr	Animals and alternatives in toxicity testing [proceedings of a meeting held at the Royal Society of London on 1 - 3 Nov. 1982 to discuss the report of the FRAME Toxicity Committee] ed. Michael Balls ...
title_full_unstemmed	Animals and alternatives in toxicity testing [proceedings of a meeting held at the Royal Society of London on 1 - 3 Nov. 1982 to discuss the report of the FRAME Toxicity Committee] ed. Michael Balls ...
title_short	Animals and alternatives in toxicity testing
title_sort	animals and alternatives in toxicity testing proceedings of a meeting held at the royal society of london on 1 3 nov 1982 to discuss the report of the frame toxicity committee
title_sub	[proceedings of a meeting held at the Royal Society of London on 1 - 3 Nov. 1982 to discuss the report of the FRAME Toxicity Committee]
topic	Animal Testing Alternatives cabt Toxicity cabt conferences cabt Tierversuch (DE-588)4060137-7 gnd Toxizitätstest (DE-588)4060540-1 gnd Alternative (DE-588)4138905-0 gnd
topic_facet	Animal Testing Alternatives Toxicity conferences Tierversuch Toxizitätstest Alternative Konferenzschrift 1982 London
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