Disease, metabolism and reproduction in the toxic response to drugs and other chemicals: proceedings of the European Society of Toxicology meeting held in Rome, March 28 - 30, 1983
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | German |
| Veröffentlicht: |
Berlin [u.a.]
Springer
1984
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| Schriftenreihe: | [Archives of toxicology / Supplement]
7 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XIII, 535 S. Ill., graph. Darst. |
| ISBN: | 3540124527 0387124527 |
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| adam_text | DISEASE, METABOLISM AND REPRODUCTION IN THE TOXIC RESPONSE TO DRUGS AND
OTHER CHEMICALS PROCEEDINGS OF THE EUROPEAN SOCIETY OF TOXICOLOGY
MEETING HELD IN ROME, MARCH 28 - 30, 1983 EDITED BY P. L. CHAMBERS, P.
PREZIOSI AND C. M. CHAMBERS *O WITH 117 FIGURES GFFL UNIVERSITATS-
SPRINGER-VERLAG BERLIN HEIDELBERG NEW YORK TOKYO 1984 CONTENTS PLENARY
LECTURE: DRUG-INDUCED CARDIONECROSIS T. GODFRAIND 1 YOUNG SCIENTISTS
AWARD LECTURE 1983: INVESTIGATIONS INTO THE MECHANISM OF
COUMARIN-INDUCED HEPATOTOXICITY IN THE RAT B. G. LAKE. WITH 5 FIGURES 16
ALTERATION OF DRUG TOXICITY IN DISEASE STATES INFLUENCE OF DISEASE ON
DRUG TOXICITY P. TURNER 33 DRUG TOXICITY AND HORMONAL DYSFUNCTION M.
ELCHELBAUM 39 ALTERATIONS OF DRUG TOXICITY IN NEUROPSYCHIATRIC DISEASE
STATES E. PERUCCA AND A. RICHENS : . 48 ALTERATIONS OF DRUG TOXICITY IN
CARDIOVASCULAR DISEASE F. LEDDA 58 THE DISEASED LUNG AND DRUGS PH. CAMUS
AND L. JEANNIN 66 LEAD IN CEREBROSPINAL FLUID IN CEREBROVASCULAR
DISEASE: ITS POSSIBLE DIAGNOSTIC, PROGNOSTIC AND TOXIC SIGNIFICANCE K.
G. KJELLIN 88 A COMPARATIVE STUDY OF ACUTE TOXICITY OF DRUGS USED DURING
ANTICANCER THERAPY IN HEALTHY AND TUMOR-BEARING MICE P. SCORZA
BARCELLONA, A. CAMPANA, V. ROSSI, C. CORRADINO AND B. SILVESTRINI ... 90
ANTITUMOUR DRUG TOXICITY IN PITUITARY OR ADRENAL-ABLATED RATS M. VACCA,
P. L. NAVARRA AND P. PREZIOSI. WITH 2 FIGURES 94 VI CONTENTS TOLERANCE
TO PITUITARY-ADRENAL AXIS ACTIVATION BY ANTICANCER DRUGS IN NORMAL AND
TUMOUR-BEARING RATS M. VACCA AND P. PREZIOSI. WITH 2 FIGURES 98 TOXINS
IN HEPATIC ENCEPHALOPATHY: THE ROLE OF THE SYNERGISTIC EFFECT OF
AMMONIA, MERCAPTANS AND SHORT CHAIN FATTY ACIDS M. BARALDI, G. PINELLI,
P. RICCI AND M. L. ZENEROLI 103 TOXIC EFFECTS ON THE MALE REPRODUCTIVE
SYSTEM EFFECTS OF DRUGS AND CHEMICALS ON SPERMATOGENESIS F. NEUMANN.
WITH 4 FIGURES 109 ASSESSMENT OF CHEMICALS AFFECTING THE MALE
REPRODUCTIVE SYSTEM R. L. DIXON. WITH 2 FIGURES 118 TOXIC AND MUTAGENIC
INFLUENCES ON SPERMATOGENESIS M. PARVINEN, J. LAHDETIE AND L.-M.
PARVINEN. WITH 6 FIGURES 128 GONADAL DAMAGE IN HODGKIN S DISEASE FROM
CANCER CHEMOTHERAPEUTIC REGIMENS G. BONADONNA, A. SANTORO, S. VIVIANI,
C. LOMBARDI AND G. RAGNI 140 APPROACHES TO THE SUPPRESSION OF TESTICULAR
FUNCTION FOR MALE FERTILITY CONTROL E. NIESCHLAG AND TH. SCHURMEYER 146
MORPHOLOGICAL CHANGES PRODUCED IN RAT TESTIS BY ANTICANCER DRUGS C.
HODEL, R. A. ETTLIN AND A. ZSCHAUER 147 ASPECTS OF TESTICULAR TOXICITY
INDUCED BY ANTICANCER DRUGS R. A. ETTLIN, R. BECHTER, I. P. LEE AND C.
HODEL. WITH 1 FIGURE 151 CHANGES IN GERMINAL TISSUE AND LEYDIG CELLS
CORRELATED WITH ETHANOL CONSUMPTION IN MALES WITH AND WITHOUT LIVER
DISEASE P. J. KARHUNEN, A. PENTTILA, K. LIESTO, A. MANNIKKO, M.
VALIMAKI, M. MOTTONEN AND R. YLIKAHRI. WITH 2 FIGURES 155 TESTICULAR
EFFECTS OF SOME XANTHINE DERIVATIVES IN THE RAT M. DAHLBACK AND A.
RYRFELDT. WITH 2 FIGURES 159 EFFECTS OF DAILY HIGH DOSES OF PARACETAMOL
GIVEN ORALLY DURING SPERMATOGENESIS IN RAT TESTES A. JACQUESON, H.
SEMONT, M. THEVENIN, J.-M. WARNET, R. PROST AND J. R. CLAUDE 164 THE
EFFECTS ON THE RAT TESTIS OF SINGLE INHALATION EXPOSURES TO ETHYLENE
GLYCOL MONOALKYL ETHERS, IN PARTICULAR ETHYLENE GLYCOL MONOMETHYL ETHER
D. M. SAMUELS, J. E. DOE AND D. J. TINSTON. WITH 2 FIGURES 167 EFFECTS
OF AN INDENOPYRIDINE DERIVATIVE, COMPOUND 20-438, ON SPERMATOGONIAL STEM
CELLS OF THE RAT K. E. SUTER. WITH 1 FIGURE 171 CONTENTS VII MONITORING
CHEMICALLY INDUCED DNA DAMAGE IN THE GERM CELLS OF MALE MICE R. R.
RACINE AND B. P. SCHMID 174 ACCUMULATION OF TOXIC METALS IN MALE
REPRODUCTION ORGANS B. R. G. DANIELSSON, L. DENCKER, A. LINDGREN AND H.
TJALVE. WITH 3 FIGURES . . . . 177 METABOLISM AND TOXICITY ACTIVE
METABOLITES IN TOXICOLOGY: THE ROLE OF CYTOCHROME P-448 AND FLAVOPROTEIN
OXIDASES D. V. PARKE AND C. IOANNIDES 183 THE ROLE OF PHARMACOKINETICS
IN THE DESIGN AND INTERPRETATION OF TOXICOLOGICAL STUDIES J. W. DANIEL
193 STRUCTURAL CHARACTERISTICS OF COMPOUNDS THAT CAN BE ACTIVATED TO
CHEMICALLY REACTIVE METABOLITES: USE FOR A PREDICTION OF A CARCINOGENIC
POTENTIAL W. K. LUTZ. WITH 6 FIGURES 194 COVALENT BINDING TO PROTEINS AS
A MECHANISM OF CHEMICAL TOXICITY C. PANTAROTTO AND C. BLONDA. WITH 5
FIGURES 208 SPECIES DIFFERENCES IN OXIDATIVE DRUG METABOLISM: SOME BASIC
CONSIDERATIONS S. G. AL-DABBAGH AND R. L. SMITH. WITH 1 FIGURE 219 HUMAN
PHARMACOKINETICS AND SAFETY OF BORIC ACID J. S. SCHOU, J. A. JANSEN AND
B. AGGERBECK. WITH 1 FIGURE 232 THE INFLUENCE OF PARACETAMOL ON THE
HEPATIC BIOSYNTHESIS OF LECITHIN J. LOHMANN, U. LESSING, H. SCHRIEWER,
M. CLEMENS AND U. GERLACH. WITH 3 FIGURES 1. . 236 DECREASED BLOOD
LEVELS OF ETHANOL AND ACETALDEHYDE BY S-ADENOSYL-L-METHIONINE IN HUMANS
C. DI PADOVA, R. TRITAPEPE, P. ROVAGNATI, M. POZZOLI AND G.
STRAMENTINOLI. WITH 2 FIGURES 240 METABOLIC ACTIVATION OF
2-AMINOFLUORENE IN THE SALMONELLA MUTAGENICITY ASSAY BY DIFFERENT S-9
PREPARATIONS G. CANTELLI FORTI, M. E. FRACASSO, P. HRELIA, R. LEONE, M.
S. VENTURINI AND M. C. GUERRA. WITH 3 FIGURES 243 REDUCTION OF COVALENT
BINDING OF AFLATOXIN B! TO RABBIT LIVER DNA AFTER IMMUNIZATION AGAINST
THIS CARCINOGEN M. CAVIEZEL, A. P. AESCHBACH, W. K. LUTZ AND C.
SCHLATTER 249 INACTIVATION OF 2-AMINO-3-METHYL-IMIDAZO (4,5-F) QUINOLINE
BY HORSE RADISH AND INTESTINAL PEROXIDASE P. DOLARA, G. CADERNI AND M.
LODOVICI. WITH 2 FIGURES 253 VIII CONTENTS THE INFLUENCE OF TWO
HISTAMINE H 2 -RECEPTOR ANTAGONISTS, CIMETIDINE AND RANITIDINE, ON THE
PLASMA LEVELS AND CLINICAL EFFECT OF NIFEDIPINE AND METOPROLOL W. KIRCH,
K. RAMSCH, H. D. JANISCH AND E. E. OHNHAUS. WITH 2 FIGURES 256
AUTORADIOGRAPHY OF 2,4 ,5-TRICHLOROBIPHENYL MERCAPTURIC ACID INDICATES
THE FORMATION OF METHYL SULPHONE METABOLITES WITH SELECTIVE AFFINITY FOR
THE BRONCHIAL MUCOSA I. BRANDT, J. BAKKE, A. BERGMAN AND P. O. DARNERUD
260 METHADONE AFFECTS THE HISTOCHEMICAL PATTERN OF
XENOBIOTIC-METABOLIZING ENZYMES IN THE LIVER OF PREGNANT RATS P. CHIECO,
P. HRELIA, S. CANDELETTI, S. FERRI AND G. CANTELLI FORTI. WITH 1 FIGURE
261 THE EFFECTS OF ACETYLCYSTEINE ON LIVER GLUTATHIONE DEPLETION AND
HEPATIC NECROSIS INDUCED BY ACETAMINOPHEN IN MICE M. LOSA, L. BONANOMI
AND A. LONGO 266 INCREASED MICROSOMAL METABOLISM OF N-HEXANE IN RAT
KIDNEY AND LIVER AFTER INHALATION OF ISOPROPANOL K. ZAHLSEN, K. AARSTAD
AND O. G. NILSEN 268 DOSE-DEPENDENT PHARMACOKINETICS OF CLOFIBRIC ACID
IN THE NON-HUMAN PRIMATE L. M. WALMSLEY. WITH 2 FIGURES 272 DIFFERENT
PATHWAYS OF CHLOROFORM METABOLISM E. TESTAI AND L. VRRROZZI. WITH 2
FIGURES 278 IN VITRO INHIBITION OF LYSOSOMAL PHOSPHOLIPASES BY
AMINOGLYCOSIDE ANTIBIOTICS: A COMPARATIVE STUDY M. B. CARLIER, G.
LAURENT AND P. TULKENS. WITH 2 FIGURES 282 ERYTHROCYTE-DEPENDENT
METABOLIC ACTIVATION OF STYRENE AND INDUCTION OF SISTER CHROMATID
EXCHANGE IN CULTURED HUMAN LYMPHOCYTES H. NORPPA, H. VAINIO, M. SORSA
AND G. BELVEDERE. WITH 2 FIGURES 286 INTERACTION OF ACRYLONITRILE WITH
THE LIVER MIXED FUNCTION OXIDASES D. COVA, E. CHIESARA AND R. RIZZI.
WITH 1 FIGURE 291 INDUCTION OF MICROSOMAL ENZYMES AFTER INHALATION OF
METHANOL K. AARSTAD, K. ZAHLSEN AND O. G. NILSEN 295 ERYTHROMYCIN
ESTOLATE IMPAIRS THE MITOCHONDRIAL AND MICROSOMAL CALCIUM HOMEOSTASIS:
CORRELATION WITH HEPATOTOXICITY P. RICHELMI, C. BALDI, L. MANZO, F.
BERTE, A. P. MARTINO, F. MIRABELLI AND G. BELLOMO. WITH 2 FIGURES 298
RELATIONSHIPS BETWEEN THE PHARMACOKINETICS OF CARBON TETRACHLORIDE
CONVERSION TO CARBON DIOXIDE AND CHLOROFORM AND LIVER INJURY E. S.
REYNOLDS, R. J. TREINEN, H. H. FARRISH AND M. T. MOSLEN 303 DISTRIBUTION
AND METABOLISM OF 2-R-BUTYL-4-METHOXYPHENOL IN THE EVERTED RAT GUT
PREPARATION L. DELLA CORTE, M. G. GIOVANNINI AND G. P. SGARAGLI. WITH 1
FIGURE 307 CONTENTS IX PHENYTOIN METABOLITES IN HUMAN PLACENTAL TISSUE
M. HENNEBERG AND E. SEROWKA 311 THE PLACENTAL TRANSFER AND DETECTION OF
14 C-CARMOISINE METABOLITES BY HPLC COMBINED WITH A RADIOACTIVITY
MONITOR (RAM) E. TRAGNI, M. MARINOVICH AND C. L. GALLI 312 TOXICITY OF
NON-STEROIDAL ANTIRHEUMATIC DRUGS: MOLECULAR MECHANISMS AND CLINICAL
ASSESSMENT A BIOCHEMICAL BASIS FOR THE GASTROINTESTINAL TOXICITY OF
NON-STEROID ANTIRHEUMATOID DRUGS B. J. R. WHITTLE AND J. R. VANE. WITH 1
FIGURE 315 MOLECULAR MECHANISMS OF THE GASTRIC TOXICITY OF ANTIRHEUMATIC
DRUGS U. AEHRINGHAUS, H. WEILER, B. A. PESKAR AND B. M. PESKAR. WITH 1
FIGURE 323 MECHANISMS OF THE NEPHROTOXICITY OF NON-STEROIDAL
ANTI-INFLAMMATORY DRUGS M. J. DUNN, L. SCHARSCHMIDT AND E. ZAMBRASKI 328
CLINICAL ASSESSMENT OF THE RENAL TOXICITY OF ANTIRHEUMATIC DRUGS G. A.
CINOTTI. WITH 2 FIGURES 338 CENTRAL AND PERIPHERAL HAEMODYNAMIC EFFECTS
OF NON-STEROIDAL ANTI-INFLAMMATORY DRUGS IN MAN A. WENNMALM, I.
CARLSSON, A. EDLUND, S. ERIKSSON, L. KAIJSER AND J. NOWAK. WITH 4
FIGURES 350 INDOMETHACIN INDUCED INTESTINAL TOXICITY IS BLOCKED BY
SODIUM SALICYLATE AT 24 AND 48 HOURS POST TREATMENT E. EZER. WITH 1
FIGURE 360 THE PRECLINICAL TOXICITY OF DAZOXIBEN: A SPECIFIC INHIBITOR
OF THROMBOXANE A 2 SYNTHETASE E. IRISARRI, M. J. KESSEDJIAN, C. CHARUEL,
J. M. FACCINI, P. GREAVES, A. M. MONRO, J. NACHBAUR AND Y.
RABEMAMPIANINA 363 SPECIES DIFFERENCES IN THE ACUTE TOXICITY OF
NON-STEROIDAL ANTI-INFLAMMATORY COM- POUNDS C. PERICIN. WITH 2 FIGURES
365 HEAVY METAL TOXICITY RENAL HANDLING OF CADMIUM: A STUDY BY TUBULAR
MICROINJECTIONS E. BOSCO, N. PORTA AND J. DIEZI. WITH 2 FIGURES 371
CADMIUM ALTERS ARTERIAL BAROREFLEX CONTROL OF HEART RATE IN THE
CONSCIOUS RAT D. GERMANO, M. POCHIERO, G. ROMEO, A. NUNZIATA, G. COSTA
AND A. P. CAPUTI. WITH 2 FIGURES 374 X CONTENTS INHIBITION OF AORTIC
VESSEL ADENOSINE DIPHOSPHATE DEGRADATION BY CADMIUM AND MERCURY G.
TOGNA, N. DOLCI AND L. CAPRINO. WITH 2 FIGURES 378 EMBRYOTOXIC ACTION
INDUCED BY MERCURY ACETATE IN THE RAT A. CERRATI, P. A. FRANCO, G.
GARRONE, C. PUNTRELLO, I. RAGGI AND F. VIOLA 382 CARDIOVASCULAR
HOMEOSTASIS IN RATS CHRONICALLY EXPOSED TO MERCURIC CHLORIDE M.
CARMIGNANI AND P. BOSCOLO 383 THE EFFECTS OF A DOSE OF MERCURIC
CHLORIDE, BELOW THE ACUTE TOXIC DOSE, ON HAEMOSTASIS IN RATS H.-P.
KLOCKING 389 IN VITRO CYTOTOXICITY OF NICKEL CHLORIDE ON A HUMAN
PULMONARY EPITHELIAL CELL LINE (A 549) A. DUBREUIL, G. BOULEY, S. DURET,
J.-C. MESTRE AND C. BOUDENE. WITH 2 FIGURES . 391 CHANGES IN ENDOGENOUS
MONOAMINE LEVELS OF RAT BRAIN INDUCED BY TETRAETHYL LEAD H. KOMULAINEN,
R. PIETARINEN AND J. TUOMISTO 394 LEVELS OF MONOAMINES IN DIFFERENT
REGIONS OF THE RAT BRAIN IN HEAVY METAL INTOXICATION V. ANANIA, M. S.
DESOLE, G. ESPOSITO, F. SANNA RANDACCIO AND E. MIELE 398 XENOBIOTIC
TOXICOLOGY EXPERIMENTAL EVIDENCE ON THE PULMONARY CARCINOGENICITY OF
ARSENIC TRIOXIDE G. PERSHAGEN, G..NORDBERG AND N.-E. BJORKLUND 403
MOLECULAR INTERACTION OF ACRYLONITRILE AT TARGET SITES OF
CARCINOGENICITY IN RATS A. E. AHMED AND M. Y. H. FAROOQUI 405 MUTAGENIC
ACTIVITY OF NITRILOACETIC ACID A. NUNZIATA, M. MONACO, N. LOPRIENO, G.
BONCRISTIANI, P. VENIER AND A. MONTALDI 407 NEUROTOXICITY IN RATS DOSED
WITH PEPPERMINT OIL AND PULEGONE P. OLSEN AND I. THORUP 408
NEUROTOXICOLOGJCAL PROFILE OF CARBON DISULPHIDE AFTER INTRAVENTRICULAR
ADMINISTRATION IN RATS D. ROTIROTI, F. NACCARI, S. GRATTERI, R. ANFOSSO
AND G. NISTICD 410 IMMEDIATE EFFECTS OF M-XYLENE ON THE HUMAN CENTRAL
NERVOUS SYSTEM K. SAVOLAINEN, J. KEKONI, V. RIIHIMAKI AND A. LAINE. WITH
2 FIGURES 412 POTENTIATION OF HEXANE AND ORGANOPHOSPHATE NEUROTOXICITIES
E. VILANOVA, J. L. VICEDO, M. D. ZAFRA AND M. C. PELLRI N 418 CONTENTS
XI BEHAVIOURAL AND ELECTROCORTICAL SPECTRUM POWER CHANGES AFTER
INTRAVENTRICULAR INJECTION OF PATULIN IN RATS G. B. DE SARRO, A. DONATO,
G. BAGETTA, A. PUJIA AND G. NISTIC6. WITH 3 FIGURES . 420 THE EFFECTS OF
RADIOLOGICAL CONTRAST MEDIA ON THE REPRODUCTION SYSTEM OF THE RAT P.
TIRONE AND E. BOLDRINI 425 SHORT-TERM STUDIES WITH THE CRYPTATING AGENT
HEXAOXA-DIAZA-BICYCLO-HEXACOSANE IN RATS M. BAUMANN, E. SCHAFFER AND H.
GREIM. WITH 2 FIGURES 427 EVALUATION OF THE TOXICOLOGICAL RISK IN
ANIMALS FOLLOWING THE INGESTION OF CHEESE OBTAINED FROM MILK WITH ADDED
FORMALDEHYDE M. MARINOVICH, P. CAMPAGNER, P. RESTANI, E. TRAGNI AND C.
L. GALLI 430 THE INFLUENCE OF SOIL PARTICLE ADSORPTION ON
2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN BIOLOGICAL UPTAKE IN THE RABBIT A.
BONACCORSI, A. DI DOMENICO, R. FANELLI, F. MERLI, R. MOTTA, R. VANZATI
AND G. A. ZAPPONI 431 THE SUBCHRONIC TOXICITY OF
3,5-DINITRO-4-CHLORO-A,A,A-TRIFLUOROTOLUENE IN THE RAT A. MACRI, A. R.
BUCCHI, C. GUASTADISEGNI, F. GRAMENZI, C. RICCIARDI AND G. SALVATORE.
WITH 1 FIGURE 435 TRIHALOMETHANE IN DRINKING WATERS: A STATISTICAL STUDY
C. CREMISINI, S. DE FULVIO, L. GIANNICO, A. PICCIONI AND G. A. ZAPPONI.
WITH 2 FIGURES 437 INHALATION TOXICOLOGY: CORRELATION BETWEEN THE
CONCENTRATION OF THE TEST COMPOUND AND THE EXPOSURE TIME USING CARBON
TETRACHLORIDE T. W. MCSHEEHY, A. NUNZIATA, P. MERCATELLI, A. ARGENTINO
AND R. O. SALERNO . 440 CIRCULATING CONCENTRATIONS OF TESTOSTERONE,
LUTEINIZING HORMONE AND FOLLICLE STIMULATING HORMONE IN MALE RATS AFTER
INHALATION OF METHANOL A. M. CAMERON, O. G. NILSEN, E. HAUG AND K. B.
EIK-NES . 441 THE EFFECT OF SODIUM SELENITE ON RESPIRATORY FUNCTION IN
MITOCHONDRIA ISOLATED FROM GUINEA PIG HEART G. IGNESTI, G. ANTONINI, F.
BENNARDINI, R. MATUCCI, G. DINI AND F. FRANCONI .... 444 INTESTINAL
ABSORPTION AND EXCRETION OF THALLIUM ( 201 TL) IN THE RAT E. SABBIONI,
A. DI NUCCI, J. EDEL, C. GREGOTTI, E. MARAFANTE AND L. MANZO. WITH 2
FIGURES 446 EVALUATION OF POLLUTION LEVELS BY ANALYSIS OF THE PESTICIDE
RESIDUES IN ALGERIAN SHEEP B. ALAMIR, A. VENANT AND L. RICHOU BAC 451
MISCELLANEOUS TOXIC EFFECTS A 2 GUANIDYL DERIVATIVE OF GENTAMICIN
(S86451) WITH REDUCED NEPHROTOXICITY: STUDIES AT LOW AND MEDIUM DOSE
LEVELS IN THE RAT P. MALDAGUE, G. LAURENT, M. B. CARLIER AND P. TULKENS.
WITH 1 FIGURE 455 XII CONTENTS TUBULAR REGENERATION IN RAT KIDNEY CORTEX
DURING TREATMENT WITH GENTAMICIN AT A LOW DOSE G. LAURENT, G. TOUBEAU,
P. MALDAGUE, M. B. CARLIER, J. A. HEUSON-STIENNON AND P. TULKENS. WITH 2
FIGURES : 459 AMINOGLYCOSIDE ANTIBIOTICS: A STUDY OF THEIR NEUROTOXIC
EFFECTS AT PERIPHERAL NERVE FIBRES D. MITOLO-CHIEPPA AND M. R. CARRATU.
WITH 1 FIGURE 464 THE USE OF PHYSOSTIGMINE IN HEROIN OVERDOSE J.
RUPREHT, B. DWORACEK, M. VALKENBURG AND H. OOSTHOEK 467 4-AMINOPYRIDINE:
AN ANTICURARE AND REAWAKENING DRUG E. MALIZIA, P. NICOLAI, R. ROMANO AND
G. PINTO 468 THE INFLUENCE OF DOSE SCHEDULES AND ADMINISTRATION ROUTES
ON THE TOXICITY OF POTENTIAL ANTIVIRAL DRUGS R. AMLACHER AND H.
HOFFMANN. WITH 1 FIGURE 469 INTRAMUSCULAR INJECTIONS AND MUSCLE DAMAGE:
EFFECTS OF CONCENTRATION, VOLUME, INJECTION SPEED AND VEHICLE O.
SVENDSEN AND L. BLOM 472 EVIDENCE OF AN INTERACTION BETWEEN OPIOIDS AND
HISTAMINERGIC SYSTEMS ON CANNABIS SATIVA-INDUCED CATALEPSY R.
ARRIGO-REINA, C. COSENTINO, M. REINA AND S. FERRI 476 FEVER REACTION OF
RABBITS AFTER REPEATED INTRAVENOUS INJECTIONS OF ANTIGENS H. RONNEBERGER
478 CARDIOVASCULAR EFFECTS OF TETANUS TOXIN AFTER SYSTEMIC AND
INTRAVENTRICULAR ADMINISTRATION IN RATS G. NISNCD, S. GRATTERI, G.
VAIRO, F. ROSSI AND E. MARMO 479 THE INCIDENCE OF DRUG OVERDOSAGE IN
PATIENTS ADMITTED TO GENERAL HOSPITALS IN THE CANARY- ISLANDS E. SANZ
AND J. BOADA 480 THE TOXIC EFFECTS OF CLOFIBRATE AND ITS METABOLITE ON
MAMMALIAN SKELETAL MUSCLE: AN ELECTROPHYSIOLOGICAL STUDY D.
CONTE-CAMERINO, V. TORTORELLA, F. FERRANINI AND S. H. BRYANT. WITH 1
FIGURE . 482 A COMPARATIVE RETROSPECTIVE ANALYSIS OF DATA FROM SHORT-
AND LONG-TERM ANIMAL TOXICITY STUDIES ON 40 PHARMACEUTICAL COMPOUNDS S.
R. WALKER, E. SCHUETZ, D. SCHUPPAN AND J. GELZER 485 CARDIAC HYPERTROPHY
IN THE DOG AND RAT INDUCED BY OXFENICINE, AN AGENT WHICH MODIFIES MUSCLE
METABOLISM P. GREAVES, J. MARTIN, M. C. MICHEL AND P. MOMPON 488 AN
EPIDEMIC OF A NEW HAEMORRHAGIC DISEASE IN INFANTS ATTRIBUTABLE TO
TALCUM POWDER CONTAMINATED WITH WARFARIN IN HO-CHI-MINH VILLE (VIETNAM)
G. MARTIN-BOUYER, N. B. KHANH, P. D. LINH AND J. TOURNEAU. WITH 3
FIGURES .... 494 CONTENTS XIII STRESS, DRUGS, AND PREGNANCY:
EXPERIMENTAL STUDIES ON EMBRYO-FOETAL TOXICITY B. LOSCALZO, A. AGRUSTA,
M. AGRUSTA. A. CRISCI, L. GENOVESE AND M. MARINO . . . 499 LONG-LASTING
HYPOTHERMIC EFFECTS OF VINCRISTINE IN RATS D. ROTIROTI, F. NACCARI, D.
AMMENDOLA, S. GRATTERI, N. DE GORI AND G. NISTIC6. WITH 3 FIGURES 500
BEHAVIOURAL CHANGES IN RATS AFTER PRENATAL ADMINISTRATION OF TYPICAL AND
ATYPICAL ANTIDEPRESSANTS V. CUOMO, I. CORTESE, R. CAGIANO, G. RENNA AND
G. RACAGNI. WITH 1 FIGURE 504 SIDE EFFECTS OF DRUGS STIMULATING
PROLACTIN SECRETION ON THE BEHAVIOR OF MALE RATS F. DRAGO AND U.
SCAPAGNINI 508 POSSIBLE ADVERSE EFFECTS ON THE CARDIOVASCULAR SYSTEM OF
AN ANTIARRHYTHMIC DRUG MEXILETINE F. ROSSI, E. RUGGIERO, M. A. SCAFURO,
M. GIASI, V. MAZZEO, G. BILE, E. LAMPARELLI AND E. MARMO. WITH 1 FIGURE
510 NOVEL AND NEW TECHNIQUES IN TOXICOLOGY A SINGLE STEP METHOD FOR THE
SEPARATION OF RAT LIVER CYTOSOLIC GLUTATHIONE S-TRANSFERASE ISOZYMES B.
BOTTI-CACCIARI, M. T. MOSLEN, E. S. REYNOLDS AND V. VANNINI. WITH 2
FIGURES . 517 IN VITRO MOUSE FERTILIZATION AS AN EXPERIMENTAL MODEL FOR
THE MONITORING OF ADVERSE EFFECTS ON GAMETES AND GAMETE FUSION B. P.
SCHMID AND R. R. RACINE 521 REPEAT DERMAL MODELS FOR SYSTEMIC TOXICITY:
A COMPARISON OF THE RABBIT, RAT AND GUINEA PIG R. J. STAAB AND W. J.
TIERNEY . . 522 A NEW CATION-EXCHANGE AND THIN LAYER CHROMATOGRAPHY
TECHNIQUE FOR THE IDENTIFICATION OF PETHIDINE IN URINE M. HENNEBERG AND
E. KWASEK 523 AUTHOR INDEX 524 SUBJECT INDEX 527 INDEXED IN CURRENT
CONTENTS
|
| any_adam_object | 1 |
| author_GND | (DE-588)120465833 |
| building | Verbundindex |
| bvnumber | BV000259399 |
| callnumber-first | R - Medicine |
| callnumber-label | RA1190 |
| callnumber-raw | RA1190 |
| callnumber-search | RA1190 |
| callnumber-sort | RA 41190 |
| callnumber-subject | RA - Public Medicine |
| classification_tum | MED 950f MED 970f |
| ctrlnum | (OCoLC)10877626 (DE-599)BVBBV000259399 |
| dewey-full | 615.9 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 615 - Pharmacology and therapeutics |
| dewey-raw | 615.9 |
| dewey-search | 615.9 |
| dewey-sort | 3615.9 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| format | Book |
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| genre | (DE-588)1071861417 Konferenzschrift 1983 Rom gnd-content |
| genre_facet | Konferenzschrift 1983 Rom |
| id | DE-604.BV000259399 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T15:11:18Z |
| institution | BVB |
| institution_GND | (DE-588)16397-1 |
| isbn | 3540124527 0387124527 |
| language | German |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-000157218 |
| oclc_num | 10877626 |
| open_access_boolean | |
| owner | DE-12 DE-20 DE-29 DE-188 DE-578 |
| owner_facet | DE-12 DE-20 DE-29 DE-188 DE-578 |
| physical | XIII, 535 S. Ill., graph. Darst. |
| publishDate | 1984 |
| publishDateSearch | 1984 |
| publishDateSort | 1984 |
| publisher | Springer |
| record_format | marc |
| series2 | [Archives of toxicology / Supplement] |
| spelling | Disease, metabolism and reproduction in the toxic response to drugs and other chemicals proceedings of the European Society of Toxicology meeting held in Rome, March 28 - 30, 1983 ed. by P. L. Chambers ... Berlin [u.a.] Springer 1984 XIII, 535 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier [Archives of toxicology / Supplement] 7 Drugs cabt Adverse Effects cabt Metabolism cabt Reproduction cabt conferences cabt Disease cabt Drug Effects cabt Toxicology cabt Drugs Metabolism Congresses Drugs Toxicology Congresses Generative organs, Male Effect of drugs on Congresses Heavy metals Toxicology Congresses Pharmaceutical Preparations adverse effects Congresses Pharmaceutical Preparations metabolism Congresses Reproduction drug effects Congresses Reproductive toxicology Congresses Toxicology Congresses Arzneimittelnebenwirkung (DE-588)4003134-2 gnd rswk-swf Toxizität (DE-588)4078372-8 gnd rswk-swf Stoffwechsel (DE-588)4057699-1 gnd rswk-swf Arzneimittel (DE-588)4003115-9 gnd rswk-swf (DE-588)1071861417 Konferenzschrift 1983 Rom gnd-content Arzneimittelnebenwirkung (DE-588)4003134-2 s DE-604 Arzneimittel (DE-588)4003115-9 s Stoffwechsel (DE-588)4057699-1 s Toxizität (DE-588)4078372-8 s Chambers, Philip L. 1931- Sonstige (DE-588)120465833 oth European Society of Toxicology Sonstige (DE-588)16397-1 oth Supplement] [Archives of toxicology 7 (DE-604)BV036826757 7 GBV Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=000157218&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Disease, metabolism and reproduction in the toxic response to drugs and other chemicals proceedings of the European Society of Toxicology meeting held in Rome, March 28 - 30, 1983 Drugs cabt Adverse Effects cabt Metabolism cabt Reproduction cabt conferences cabt Disease cabt Drug Effects cabt Toxicology cabt Drugs Metabolism Congresses Drugs Toxicology Congresses Generative organs, Male Effect of drugs on Congresses Heavy metals Toxicology Congresses Pharmaceutical Preparations adverse effects Congresses Pharmaceutical Preparations metabolism Congresses Reproduction drug effects Congresses Reproductive toxicology Congresses Toxicology Congresses Arzneimittelnebenwirkung (DE-588)4003134-2 gnd Toxizität (DE-588)4078372-8 gnd Stoffwechsel (DE-588)4057699-1 gnd Arzneimittel (DE-588)4003115-9 gnd |
| subject_GND | (DE-588)4003134-2 (DE-588)4078372-8 (DE-588)4057699-1 (DE-588)4003115-9 (DE-588)1071861417 |
| title | Disease, metabolism and reproduction in the toxic response to drugs and other chemicals proceedings of the European Society of Toxicology meeting held in Rome, March 28 - 30, 1983 |
| title_auth | Disease, metabolism and reproduction in the toxic response to drugs and other chemicals proceedings of the European Society of Toxicology meeting held in Rome, March 28 - 30, 1983 |
| title_exact_search | Disease, metabolism and reproduction in the toxic response to drugs and other chemicals proceedings of the European Society of Toxicology meeting held in Rome, March 28 - 30, 1983 |
| title_full | Disease, metabolism and reproduction in the toxic response to drugs and other chemicals proceedings of the European Society of Toxicology meeting held in Rome, March 28 - 30, 1983 ed. by P. L. Chambers ... |
| title_fullStr | Disease, metabolism and reproduction in the toxic response to drugs and other chemicals proceedings of the European Society of Toxicology meeting held in Rome, March 28 - 30, 1983 ed. by P. L. Chambers ... |
| title_full_unstemmed | Disease, metabolism and reproduction in the toxic response to drugs and other chemicals proceedings of the European Society of Toxicology meeting held in Rome, March 28 - 30, 1983 ed. by P. L. Chambers ... |
| title_short | Disease, metabolism and reproduction in the toxic response to drugs and other chemicals |
| title_sort | disease metabolism and reproduction in the toxic response to drugs and other chemicals proceedings of the european society of toxicology meeting held in rome march 28 30 1983 |
| title_sub | proceedings of the European Society of Toxicology meeting held in Rome, March 28 - 30, 1983 |
| topic | Drugs cabt Adverse Effects cabt Metabolism cabt Reproduction cabt conferences cabt Disease cabt Drug Effects cabt Toxicology cabt Drugs Metabolism Congresses Drugs Toxicology Congresses Generative organs, Male Effect of drugs on Congresses Heavy metals Toxicology Congresses Pharmaceutical Preparations adverse effects Congresses Pharmaceutical Preparations metabolism Congresses Reproduction drug effects Congresses Reproductive toxicology Congresses Toxicology Congresses Arzneimittelnebenwirkung (DE-588)4003134-2 gnd Toxizität (DE-588)4078372-8 gnd Stoffwechsel (DE-588)4057699-1 gnd Arzneimittel (DE-588)4003115-9 gnd |
| topic_facet | Drugs Adverse Effects Metabolism Reproduction conferences Disease Drug Effects Toxicology Drugs Metabolism Congresses Drugs Toxicology Congresses Generative organs, Male Effect of drugs on Congresses Heavy metals Toxicology Congresses Pharmaceutical Preparations adverse effects Congresses Pharmaceutical Preparations metabolism Congresses Reproduction drug effects Congresses Reproductive toxicology Congresses Toxicology Congresses Arzneimittelnebenwirkung Toxizität Stoffwechsel Arzneimittel Konferenzschrift 1983 Rom |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=000157218&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| volume_link | (DE-604)BV036826757 |
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