The handbook of medicinal chemistry :: principles and practice /
The 2nd edition of The Handbook of Medicinal Chemistry is a carefully curated compilation of writing from global experts. Using their broad experience of medicinal chemistry, project leadership and drug discovery from both industry, academic and charity perspectives they are able to provide unparall...
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| Weitere Verfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Cambridge :
Royal Society of Chemistry,
[2023]
|
| Ausgabe: | 2nd edition. |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Zusammenfassung: | The 2nd edition of The Handbook of Medicinal Chemistry is a carefully curated compilation of writing from global experts. Using their broad experience of medicinal chemistry, project leadership and drug discovery from both industry, academic and charity perspectives they are able to provide unparalleled insight into the field in a single, invaluable volume.|bCompletely revised and updated, the 2nd edition of The Handbook of Medicinal Chemistry draws together contributions from authoritative practitioners to provide a comprehensive overview of the field as well as insight into the latest trends and research. An ideal companion for students in medicinal chemistry, drug discovery and drug development, while also communicating core principles, the book places the discipline within the context of the burgeoning platform of new modalities now available to drug discovery. The book also highlights the role chemistry has to play in wider target validation and translational technologies. This is a carefully curated compilation of writing from global experts using their broad experience of medicinal chemistry, project leadership and drug discovery and development from an industry, academic and charity perspective to provide unparalleled insight into the field. |
| Beschreibung: | Previous edition: 2015. |
| Beschreibung: | 1 online resource. |
| Bibliographie: | Includes bibliographical references and index. |
| ISBN: | 9781839165887 183916588X |
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| 504 | |a Includes bibliographical references and index. | ||
| 505 | 0 | |a Physicochemical Properties; Synthesis in Medicinal Chemistry; Useful Computational Chemistry Tools for Medicinal Chemistry; Structure-based Design for Medicinal Chemists; Fragment-based Ligand Discovery; Machine Learning in Drug Design; Drug Metabolism; ADME Optimization in Drug Discovery; Molecular Biology for Medicinal Chemists; Assays; In Vitro Biology: Measuring Pharmacological Activity That Will Translate to Clinical Efficacy; Animal Models: Practical Use and Considerations; Bioinformatics for Medicinal Chemistry; Translational Science; Discovery Toxicology in Lead Optimization; Toxicology and Drug Development; Patents for Medicines; Target Validation for Medicinal Chemists; Lead Optimisation: What you should know!; Pharmaceutical Properties -- The Importance of Solid Form Selection; The Medicinal Chemistry and Process Chemistry Interface; Clinical Drug Development; SMN2 Splicing Modification by Small Molecules -- A Blueprint to Tackle the Underlying Genetic Cause of Many Underserved Diseases; The Discovery of Checkpoint Kinase 1 Inhibitors: From Fragments to Clinical Candidate; Medicinal Chemistry for Neglected Diseases -- Malaria, Tuberculosis, Sleeping Sickness, Leishmaniasis and River Blindness; New Therapeutic Chemical Modalities: Compositions, Modes-of-action, and Drug Discovery | |
| 520 | |a The 2nd edition of The Handbook of Medicinal Chemistry is a carefully curated compilation of writing from global experts. Using their broad experience of medicinal chemistry, project leadership and drug discovery from both industry, academic and charity perspectives they are able to provide unparalleled insight into the field in a single, invaluable volume.|bCompletely revised and updated, the 2nd edition of The Handbook of Medicinal Chemistry draws together contributions from authoritative practitioners to provide a comprehensive overview of the field as well as insight into the latest trends and research. An ideal companion for students in medicinal chemistry, drug discovery and drug development, while also communicating core principles, the book places the discipline within the context of the burgeoning platform of new modalities now available to drug discovery. The book also highlights the role chemistry has to play in wider target validation and translational technologies. This is a carefully curated compilation of writing from global experts using their broad experience of medicinal chemistry, project leadership and drug discovery and development from an industry, academic and charity perspective to provide unparalleled insight into the field. | ||
| 650 | 0 | |a Pharmaceutical chemistry. |0 http://id.loc.gov/authorities/subjects/sh85023026 | |
| 650 | 0 | |a Drug development. |0 http://id.loc.gov/authorities/subjects/sh97007921 | |
| 650 | 0 | |a Drugs. |0 http://id.loc.gov/authorities/subjects/sh85039719 | |
| 650 | 2 | |a Chemistry, Pharmaceutical |0 https://id.nlm.nih.gov/mesh/D002626 | |
| 650 | 2 | |a Pharmaceutical Preparations |0 https://id.nlm.nih.gov/mesh/D004364 | |
| 650 | 6 | |a Chimie pharmaceutique. | |
| 650 | 6 | |a Médicaments |x Développement. | |
| 650 | 6 | |a Médicaments. | |
| 650 | 7 | |a Drug development |2 fast | |
| 650 | 7 | |a Pharmaceutical chemistry |2 fast | |
| 700 | 1 | |a Ward, Simon E. |q (Simon Edward), |e editor. |1 https://id.oclc.org/worldcat/entity/E39PCjqV3X9p9FtrDWWVJH3gfC |0 http://id.loc.gov/authorities/names/nb2015001328 | |
| 700 | 1 | |a Davis, Andrew M. |c (Chemist), |e editor. |1 https://id.oclc.org/worldcat/entity/E39PCjqPrdGYFGy38XtwTRMCcd |0 http://id.loc.gov/authorities/names/nb2015001322 | |
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| contents | Physicochemical Properties; Synthesis in Medicinal Chemistry; Useful Computational Chemistry Tools for Medicinal Chemistry; Structure-based Design for Medicinal Chemists; Fragment-based Ligand Discovery; Machine Learning in Drug Design; Drug Metabolism; ADME Optimization in Drug Discovery; Molecular Biology for Medicinal Chemists; Assays; In Vitro Biology: Measuring Pharmacological Activity That Will Translate to Clinical Efficacy; Animal Models: Practical Use and Considerations; Bioinformatics for Medicinal Chemistry; Translational Science; Discovery Toxicology in Lead Optimization; Toxicology and Drug Development; Patents for Medicines; Target Validation for Medicinal Chemists; Lead Optimisation: What you should know!; Pharmaceutical Properties -- The Importance of Solid Form Selection; The Medicinal Chemistry and Process Chemistry Interface; Clinical Drug Development; SMN2 Splicing Modification by Small Molecules -- A Blueprint to Tackle the Underlying Genetic Cause of Many Underserved Diseases; The Discovery of Checkpoint Kinase 1 Inhibitors: From Fragments to Clinical Candidate; Medicinal Chemistry for Neglected Diseases -- Malaria, Tuberculosis, Sleeping Sickness, Leishmaniasis and River Blindness; New Therapeutic Chemical Modalities: Compositions, Modes-of-action, and Drug Discovery |
| ctrlnum | (OCoLC)1374215010 |
| dewey-full | 615.19 |
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| dewey-ones | 615 - Pharmacology and therapeutics |
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| discipline | Medizin |
| edition | 2nd edition. |
| format | Electronic eBook |
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| illustrated | Not Illustrated |
| indexdate | 2024-11-27T13:30:42Z |
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| spelling | The handbook of medicinal chemistry : principles and practice / edited by Simon E. Ward and Andrew M. Davis. 2nd edition. Cambridge : Royal Society of Chemistry, [2023] ©2023 1 online resource. text txt rdacontent computer c rdamedia online resource cr rdacarrier Print version record. Previous edition: 2015. Includes bibliographical references and index. Physicochemical Properties; Synthesis in Medicinal Chemistry; Useful Computational Chemistry Tools for Medicinal Chemistry; Structure-based Design for Medicinal Chemists; Fragment-based Ligand Discovery; Machine Learning in Drug Design; Drug Metabolism; ADME Optimization in Drug Discovery; Molecular Biology for Medicinal Chemists; Assays; In Vitro Biology: Measuring Pharmacological Activity That Will Translate to Clinical Efficacy; Animal Models: Practical Use and Considerations; Bioinformatics for Medicinal Chemistry; Translational Science; Discovery Toxicology in Lead Optimization; Toxicology and Drug Development; Patents for Medicines; Target Validation for Medicinal Chemists; Lead Optimisation: What you should know!; Pharmaceutical Properties -- The Importance of Solid Form Selection; The Medicinal Chemistry and Process Chemistry Interface; Clinical Drug Development; SMN2 Splicing Modification by Small Molecules -- A Blueprint to Tackle the Underlying Genetic Cause of Many Underserved Diseases; The Discovery of Checkpoint Kinase 1 Inhibitors: From Fragments to Clinical Candidate; Medicinal Chemistry for Neglected Diseases -- Malaria, Tuberculosis, Sleeping Sickness, Leishmaniasis and River Blindness; New Therapeutic Chemical Modalities: Compositions, Modes-of-action, and Drug Discovery The 2nd edition of The Handbook of Medicinal Chemistry is a carefully curated compilation of writing from global experts. Using their broad experience of medicinal chemistry, project leadership and drug discovery from both industry, academic and charity perspectives they are able to provide unparalleled insight into the field in a single, invaluable volume.|bCompletely revised and updated, the 2nd edition of The Handbook of Medicinal Chemistry draws together contributions from authoritative practitioners to provide a comprehensive overview of the field as well as insight into the latest trends and research. An ideal companion for students in medicinal chemistry, drug discovery and drug development, while also communicating core principles, the book places the discipline within the context of the burgeoning platform of new modalities now available to drug discovery. The book also highlights the role chemistry has to play in wider target validation and translational technologies. This is a carefully curated compilation of writing from global experts using their broad experience of medicinal chemistry, project leadership and drug discovery and development from an industry, academic and charity perspective to provide unparalleled insight into the field. Pharmaceutical chemistry. http://id.loc.gov/authorities/subjects/sh85023026 Drug development. http://id.loc.gov/authorities/subjects/sh97007921 Drugs. http://id.loc.gov/authorities/subjects/sh85039719 Chemistry, Pharmaceutical https://id.nlm.nih.gov/mesh/D002626 Pharmaceutical Preparations https://id.nlm.nih.gov/mesh/D004364 Chimie pharmaceutique. Médicaments Développement. Médicaments. Drug development fast Pharmaceutical chemistry fast Ward, Simon E. (Simon Edward), editor. https://id.oclc.org/worldcat/entity/E39PCjqV3X9p9FtrDWWVJH3gfC http://id.loc.gov/authorities/names/nb2015001328 Davis, Andrew M. (Chemist), editor. https://id.oclc.org/worldcat/entity/E39PCjqPrdGYFGy38XtwTRMCcd http://id.loc.gov/authorities/names/nb2015001322 has work: The handbook of medicinal chemistry (Text) https://id.oclc.org/worldcat/entity/E39PCGxg7Xt49RyxD84QVQkyQy https://id.oclc.org/worldcat/ontology/hasWork Print version: HANDBOOK OF MEDICINAL CHEMISTRY. [Place of publication not identified] : ROYAL SOCIETY OF CHEMISTR, 2022 1788018982 (OCoLC)1331704492 FWS01 ZDB-4-EBA FWS_PDA_EBA https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=3580101 Volltext |
| spellingShingle | The handbook of medicinal chemistry : principles and practice / Physicochemical Properties; Synthesis in Medicinal Chemistry; Useful Computational Chemistry Tools for Medicinal Chemistry; Structure-based Design for Medicinal Chemists; Fragment-based Ligand Discovery; Machine Learning in Drug Design; Drug Metabolism; ADME Optimization in Drug Discovery; Molecular Biology for Medicinal Chemists; Assays; In Vitro Biology: Measuring Pharmacological Activity That Will Translate to Clinical Efficacy; Animal Models: Practical Use and Considerations; Bioinformatics for Medicinal Chemistry; Translational Science; Discovery Toxicology in Lead Optimization; Toxicology and Drug Development; Patents for Medicines; Target Validation for Medicinal Chemists; Lead Optimisation: What you should know!; Pharmaceutical Properties -- The Importance of Solid Form Selection; The Medicinal Chemistry and Process Chemistry Interface; Clinical Drug Development; SMN2 Splicing Modification by Small Molecules -- A Blueprint to Tackle the Underlying Genetic Cause of Many Underserved Diseases; The Discovery of Checkpoint Kinase 1 Inhibitors: From Fragments to Clinical Candidate; Medicinal Chemistry for Neglected Diseases -- Malaria, Tuberculosis, Sleeping Sickness, Leishmaniasis and River Blindness; New Therapeutic Chemical Modalities: Compositions, Modes-of-action, and Drug Discovery Pharmaceutical chemistry. http://id.loc.gov/authorities/subjects/sh85023026 Drug development. http://id.loc.gov/authorities/subjects/sh97007921 Drugs. http://id.loc.gov/authorities/subjects/sh85039719 Chemistry, Pharmaceutical https://id.nlm.nih.gov/mesh/D002626 Pharmaceutical Preparations https://id.nlm.nih.gov/mesh/D004364 Chimie pharmaceutique. Médicaments Développement. Médicaments. Drug development fast Pharmaceutical chemistry fast |
| subject_GND | http://id.loc.gov/authorities/subjects/sh85023026 http://id.loc.gov/authorities/subjects/sh97007921 http://id.loc.gov/authorities/subjects/sh85039719 https://id.nlm.nih.gov/mesh/D002626 https://id.nlm.nih.gov/mesh/D004364 |
| title | The handbook of medicinal chemistry : principles and practice / |
| title_auth | The handbook of medicinal chemistry : principles and practice / |
| title_exact_search | The handbook of medicinal chemistry : principles and practice / |
| title_full | The handbook of medicinal chemistry : principles and practice / edited by Simon E. Ward and Andrew M. Davis. |
| title_fullStr | The handbook of medicinal chemistry : principles and practice / edited by Simon E. Ward and Andrew M. Davis. |
| title_full_unstemmed | The handbook of medicinal chemistry : principles and practice / edited by Simon E. Ward and Andrew M. Davis. |
| title_short | The handbook of medicinal chemistry : |
| title_sort | handbook of medicinal chemistry principles and practice |
| title_sub | principles and practice / |
| topic | Pharmaceutical chemistry. http://id.loc.gov/authorities/subjects/sh85023026 Drug development. http://id.loc.gov/authorities/subjects/sh97007921 Drugs. http://id.loc.gov/authorities/subjects/sh85039719 Chemistry, Pharmaceutical https://id.nlm.nih.gov/mesh/D002626 Pharmaceutical Preparations https://id.nlm.nih.gov/mesh/D004364 Chimie pharmaceutique. Médicaments Développement. Médicaments. Drug development fast Pharmaceutical chemistry fast |
| topic_facet | Pharmaceutical chemistry. Drug development. Drugs. Chemistry, Pharmaceutical Pharmaceutical Preparations Chimie pharmaceutique. Médicaments Développement. Médicaments. Drug development Pharmaceutical chemistry |
| url | https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=3580101 |
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