In vitro and in vivo development of a topical drug for the treatment of equine skin cancer - based on naturally occurring and synthetically modified substances in plane bark:
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Göttingen :
Cuvillier Verlag,
2021.
|
| Schriftenreihe: | Wissenschaftliche Reihe der Klinik für Pferde.
|
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Beschreibung: | Description based upon print version of record. |
| Beschreibung: | 1 online resource (141 p.). |
| ISBN: | 3736964323 9783736964327 |
Internformat
MARC
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| 035 | |a (OCoLC)1256237389 | ||
| 050 | 4 | |a SF959.S54 | |
| 082 | 7 | |a 636.108965 |2 23/eng/20220829 | |
| 049 | |a MAIN | ||
| 100 | 1 | |a Weber, Lisa Annabel. | |
| 245 | 1 | 0 | |a In vitro and in vivo development of a topical drug for the treatment of equine skin cancer - based on naturally occurring and synthetically modified substances in plane bark |h [electronic resource]. |
| 260 | |a Göttingen : |b Cuvillier Verlag, |c 2021. | ||
| 300 | |a 1 online resource (141 p.). | ||
| 490 | 1 | |a Wissenschaftliche Reihe der Klinik für Pferde ; |v v.51 | |
| 500 | |a Description based upon print version of record. | ||
| 505 | 0 | |a Intro -- LIST OF ABBREVIATIONS -- SUMMARY -- ZUSAMMENFASSUNG -- 1. Introduction -- 1.1. The equine malignant melanoma -- 1.2. The equine sarcoid: an overview -- 1.3. Topical drug application -- 1.4. Naturally occurring substances in plane bark and their syntheticallymodified derivatives -- 1.5. Hypotheses and aims of the thesis -- 2. Manuscript I:Betulinic acid shows anticancer activity against equine melanoma cells andpermeates isolated equine skin in vitro -- 2.1. Supplemental data | |
| 505 | 8 | |a 3. Manuscript II:In vitro assessment of triterpenoids NVX-207 and betulinyl-bis-sulfamate asa topical treatment for equine skin cancer -- 4. Manuscript III:Concentration profiles and safety of topically applied betulinic acid andNVX-207 in eight healthy horses -- A randomized, blinded, placebocontrolled,crossover pilot study -- 5. Manuscript IV:Effects of topically applied betulinic acid and NVX-207 on early stageequine melanoma -- A prospective, randomized, double-blind, placebocontrolledpilot study -- 6. General discussion -- 6.1. Summarized findings -- 6.2. Interpretation of the findings | |
| 505 | 8 | |a 7. Major findings and conclusions -- 8. Future perspectives -- 9. References -- Affidavit -- Acknowledgements | |
| 650 | 0 | |a Horses |x Diseases. |0 http://id.loc.gov/authorities/subjects/sh85062163 | |
| 650 | 0 | |8 7\p |a Skin |x Cancer. |0 http://id.loc.gov/authorities/subjects/sh85123168 | |
| 650 | 0 | |8 8\p |a Bark. |0 http://id.loc.gov/authorities/subjects/sh85011862 | |
| 650 | 6 | |a Chevaux |x Maladies. | |
| 650 | 6 | |a Peau |x Cancer. | |
| 650 | 6 | |a Écorce. | |
| 650 | 7 | |a bark (plant material) |2 aat | |
| 650 | 7 | |a Bark |2 fast | |
| 650 | 7 | |a Horses |x Diseases |2 fast | |
| 650 | 7 | |a Skin |x Cancer |2 fast | |
| 655 | 4 | |a Electronic book. | |
| 758 | |i has work: |a In vitro and in vivo development of a topical drug for the treatment of equine skin cancer - based on naturally occurring and synthetically modified substances in plane bark (Text) |1 https://id.oclc.org/worldcat/entity/E39PCG7YjGfxhDqbHHkG43m9Tb |4 https://id.oclc.org/worldcat/ontology/hasWork | ||
| 776 | 0 | 8 | |i Print version: |a Weber, Lisa Annabel |t In vitro and in vivo development of a topical drug for the treatment of equine skin cancer - based on naturally occurring and synthetically modified substances in plane bark |d Göttingen : Cuvillier Verlag,c2021 |z 9783736974326 |
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| 938 | |a ProQuest Ebook Central |b EBLB |n EBL6636881 | ||
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| 049 | |a DE-863 | ||
Datensatz im Suchindex
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|---|---|
| _version_ | 1816882545526046720 |
| adam_text | |
| any_adam_object | |
| author | Weber, Lisa Annabel |
| author_facet | Weber, Lisa Annabel |
| author_role | |
| author_sort | Weber, Lisa Annabel |
| author_variant | l a w la law |
| building | Verbundindex |
| bvnumber | localFWS |
| callnumber-first | S - Agriculture |
| callnumber-label | SF959 |
| callnumber-raw | SF959.S54 |
| callnumber-search | SF959.S54 |
| callnumber-sort | SF 3959 S54 |
| callnumber-subject | SF - Animal Culture |
| collection | ZDB-4-EBA |
| contents | Intro -- LIST OF ABBREVIATIONS -- SUMMARY -- ZUSAMMENFASSUNG -- 1. Introduction -- 1.1. The equine malignant melanoma -- 1.2. The equine sarcoid: an overview -- 1.3. Topical drug application -- 1.4. Naturally occurring substances in plane bark and their syntheticallymodified derivatives -- 1.5. Hypotheses and aims of the thesis -- 2. Manuscript I:Betulinic acid shows anticancer activity against equine melanoma cells andpermeates isolated equine skin in vitro -- 2.1. Supplemental data 3. Manuscript II:In vitro assessment of triterpenoids NVX-207 and betulinyl-bis-sulfamate asa topical treatment for equine skin cancer -- 4. Manuscript III:Concentration profiles and safety of topically applied betulinic acid andNVX-207 in eight healthy horses -- A randomized, blinded, placebocontrolled,crossover pilot study -- 5. Manuscript IV:Effects of topically applied betulinic acid and NVX-207 on early stageequine melanoma -- A prospective, randomized, double-blind, placebocontrolledpilot study -- 6. General discussion -- 6.1. Summarized findings -- 6.2. Interpretation of the findings 7. Major findings and conclusions -- 8. Future perspectives -- 9. References -- Affidavit -- Acknowledgements |
| ctrlnum | (OCoLC)1256237389 |
| dewey-full | 636.108965 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 636 - Animal husbandry |
| dewey-raw | 636.108965 |
| dewey-search | 636.108965 |
| dewey-sort | 3636.108965 |
| dewey-tens | 630 - Agriculture and related technologies |
| discipline | Agrar-/Forst-/Ernährungs-/Haushaltswissenschaft / Gartenbau |
| format | Electronic eBook |
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| genre | Electronic book. |
| genre_facet | Electronic book. |
| id | ZDB-4-EBA-on1256237389 |
| illustrated | Not Illustrated |
| indexdate | 2024-11-27T13:30:19Z |
| institution | BVB |
| isbn | 3736964323 9783736964327 |
| language | English |
| oclc_num | 1256237389 |
| open_access_boolean | |
| owner | MAIN DE-863 DE-BY-FWS |
| owner_facet | MAIN DE-863 DE-BY-FWS |
| physical | 1 online resource (141 p.). |
| psigel | ZDB-4-EBA |
| publishDate | 2021 |
| publishDateSearch | 2021 |
| publishDateSort | 2021 |
| publisher | Cuvillier Verlag, |
| record_format | marc |
| series | Wissenschaftliche Reihe der Klinik für Pferde. |
| series2 | Wissenschaftliche Reihe der Klinik für Pferde ; |
| spelling | Weber, Lisa Annabel. In vitro and in vivo development of a topical drug for the treatment of equine skin cancer - based on naturally occurring and synthetically modified substances in plane bark [electronic resource]. Göttingen : Cuvillier Verlag, 2021. 1 online resource (141 p.). Wissenschaftliche Reihe der Klinik für Pferde ; v.51 Description based upon print version of record. Intro -- LIST OF ABBREVIATIONS -- SUMMARY -- ZUSAMMENFASSUNG -- 1. Introduction -- 1.1. The equine malignant melanoma -- 1.2. The equine sarcoid: an overview -- 1.3. Topical drug application -- 1.4. Naturally occurring substances in plane bark and their syntheticallymodified derivatives -- 1.5. Hypotheses and aims of the thesis -- 2. Manuscript I:Betulinic acid shows anticancer activity against equine melanoma cells andpermeates isolated equine skin in vitro -- 2.1. Supplemental data 3. Manuscript II:In vitro assessment of triterpenoids NVX-207 and betulinyl-bis-sulfamate asa topical treatment for equine skin cancer -- 4. Manuscript III:Concentration profiles and safety of topically applied betulinic acid andNVX-207 in eight healthy horses -- A randomized, blinded, placebocontrolled,crossover pilot study -- 5. Manuscript IV:Effects of topically applied betulinic acid and NVX-207 on early stageequine melanoma -- A prospective, randomized, double-blind, placebocontrolledpilot study -- 6. General discussion -- 6.1. Summarized findings -- 6.2. Interpretation of the findings 7. Major findings and conclusions -- 8. Future perspectives -- 9. References -- Affidavit -- Acknowledgements Horses Diseases. http://id.loc.gov/authorities/subjects/sh85062163 7\p Skin Cancer. http://id.loc.gov/authorities/subjects/sh85123168 8\p Bark. http://id.loc.gov/authorities/subjects/sh85011862 Chevaux Maladies. Peau Cancer. Écorce. bark (plant material) aat Bark fast Horses Diseases fast Skin Cancer fast Electronic book. has work: In vitro and in vivo development of a topical drug for the treatment of equine skin cancer - based on naturally occurring and synthetically modified substances in plane bark (Text) https://id.oclc.org/worldcat/entity/E39PCG7YjGfxhDqbHHkG43m9Tb https://id.oclc.org/worldcat/ontology/hasWork Print version: Weber, Lisa Annabel In vitro and in vivo development of a topical drug for the treatment of equine skin cancer - based on naturally occurring and synthetically modified substances in plane bark Göttingen : Cuvillier Verlag,c2021 9783736974326 Wissenschaftliche Reihe der Klinik für Pferde. FWS01 ZDB-4-EBA FWS_PDA_EBA https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=2942402 Volltext |
| spellingShingle | Weber, Lisa Annabel In vitro and in vivo development of a topical drug for the treatment of equine skin cancer - based on naturally occurring and synthetically modified substances in plane bark Wissenschaftliche Reihe der Klinik für Pferde. Intro -- LIST OF ABBREVIATIONS -- SUMMARY -- ZUSAMMENFASSUNG -- 1. Introduction -- 1.1. The equine malignant melanoma -- 1.2. The equine sarcoid: an overview -- 1.3. Topical drug application -- 1.4. Naturally occurring substances in plane bark and their syntheticallymodified derivatives -- 1.5. Hypotheses and aims of the thesis -- 2. Manuscript I:Betulinic acid shows anticancer activity against equine melanoma cells andpermeates isolated equine skin in vitro -- 2.1. Supplemental data 3. Manuscript II:In vitro assessment of triterpenoids NVX-207 and betulinyl-bis-sulfamate asa topical treatment for equine skin cancer -- 4. Manuscript III:Concentration profiles and safety of topically applied betulinic acid andNVX-207 in eight healthy horses -- A randomized, blinded, placebocontrolled,crossover pilot study -- 5. Manuscript IV:Effects of topically applied betulinic acid and NVX-207 on early stageequine melanoma -- A prospective, randomized, double-blind, placebocontrolledpilot study -- 6. General discussion -- 6.1. Summarized findings -- 6.2. Interpretation of the findings 7. Major findings and conclusions -- 8. Future perspectives -- 9. References -- Affidavit -- Acknowledgements Horses Diseases. http://id.loc.gov/authorities/subjects/sh85062163 7\p Skin Cancer. http://id.loc.gov/authorities/subjects/sh85123168 8\p Bark. http://id.loc.gov/authorities/subjects/sh85011862 Chevaux Maladies. Peau Cancer. Écorce. bark (plant material) aat Bark fast Horses Diseases fast Skin Cancer fast |
| subject_GND | http://id.loc.gov/authorities/subjects/sh85062163 http://id.loc.gov/authorities/subjects/sh85123168 http://id.loc.gov/authorities/subjects/sh85011862 |
| title | In vitro and in vivo development of a topical drug for the treatment of equine skin cancer - based on naturally occurring and synthetically modified substances in plane bark |
| title_auth | In vitro and in vivo development of a topical drug for the treatment of equine skin cancer - based on naturally occurring and synthetically modified substances in plane bark |
| title_exact_search | In vitro and in vivo development of a topical drug for the treatment of equine skin cancer - based on naturally occurring and synthetically modified substances in plane bark |
| title_full | In vitro and in vivo development of a topical drug for the treatment of equine skin cancer - based on naturally occurring and synthetically modified substances in plane bark [electronic resource]. |
| title_fullStr | In vitro and in vivo development of a topical drug for the treatment of equine skin cancer - based on naturally occurring and synthetically modified substances in plane bark [electronic resource]. |
| title_full_unstemmed | In vitro and in vivo development of a topical drug for the treatment of equine skin cancer - based on naturally occurring and synthetically modified substances in plane bark [electronic resource]. |
| title_short | In vitro and in vivo development of a topical drug for the treatment of equine skin cancer - based on naturally occurring and synthetically modified substances in plane bark |
| title_sort | in vitro and in vivo development of a topical drug for the treatment of equine skin cancer based on naturally occurring and synthetically modified substances in plane bark |
| topic | Horses Diseases. http://id.loc.gov/authorities/subjects/sh85062163 7\p Skin Cancer. http://id.loc.gov/authorities/subjects/sh85123168 8\p Bark. http://id.loc.gov/authorities/subjects/sh85011862 Chevaux Maladies. Peau Cancer. Écorce. bark (plant material) aat Bark fast Horses Diseases fast Skin Cancer fast |
| topic_facet | Horses Diseases. Skin Cancer. Bark. Chevaux Maladies. Peau Cancer. Écorce. bark (plant material) Bark Horses Diseases Skin Cancer Electronic book. |
| url | https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=2942402 |
| work_keys_str_mv | AT weberlisaannabel invitroandinvivodevelopmentofatopicaldrugforthetreatmentofequineskincancerbasedonnaturallyoccurringandsyntheticallymodifiedsubstancesinplanebark |