First in fly :: Drosophila research and biological discovery /
A single species of fly, Drosophila melanogaster, has been the subject of scientific research for more than one hundred years. Why does this tiny insect merit such intense scrutiny? Drosophila's importance as a research organism began with its short life cycle, ability to reproduce in large num...
Gespeichert in:
| 1. Verfasser: | |
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| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Cambridge, Massachusetts :
Harvard University Press,
2018.
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| Schlagworte: | |
| Online-Zugang: | Volltext |
| Zusammenfassung: | A single species of fly, Drosophila melanogaster, has been the subject of scientific research for more than one hundred years. Why does this tiny insect merit such intense scrutiny? Drosophila's importance as a research organism began with its short life cycle, ability to reproduce in large numbers, and easy-to-see mutant phenotypes. Over time, laboratory investigation revealed surprising similarities between flies and other animals at the level of genes, gene networks, cell interactions, physiology, immunity, and behavior. Like humans, flies learn and remember, fight microbial infection, and slow down as they age. Scientists use Drosophila to investigate complex biological activities in a simple but intact living system. Fly research provides answers to some of the most challenging questions in biology and biomedicine, including how cells transmit signals and form ordered structures, how we can interpret the wealth of human genome data now available, and how we can develop effective treatments for cancer, diabetes, and neurodegenerative diseases. This book notes insights uncovered by investigators using this model organism. The author draws on these "first in fly" findings to introduce fundamental biological concepts gained over the last century and explore how research in the common fruit fly has expanded our understanding of human health and disease.-- |
| Beschreibung: | 1 online resource (xii, 257 pages) : illustrations |
| Bibliographie: | Includes bibliographical references and index. |
| ISBN: | 9780674984721 0674984722 0674984730 9780674984738 |
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| 520 | |a A single species of fly, Drosophila melanogaster, has been the subject of scientific research for more than one hundred years. Why does this tiny insect merit such intense scrutiny? Drosophila's importance as a research organism began with its short life cycle, ability to reproduce in large numbers, and easy-to-see mutant phenotypes. Over time, laboratory investigation revealed surprising similarities between flies and other animals at the level of genes, gene networks, cell interactions, physiology, immunity, and behavior. Like humans, flies learn and remember, fight microbial infection, and slow down as they age. Scientists use Drosophila to investigate complex biological activities in a simple but intact living system. Fly research provides answers to some of the most challenging questions in biology and biomedicine, including how cells transmit signals and form ordered structures, how we can interpret the wealth of human genome data now available, and how we can develop effective treatments for cancer, diabetes, and neurodegenerative diseases. This book notes insights uncovered by investigators using this model organism. The author draws on these "first in fly" findings to introduce fundamental biological concepts gained over the last century and explore how research in the common fruit fly has expanded our understanding of human health and disease.-- |c Provided by publisher | ||
| 504 | |a Includes bibliographical references and index. | ||
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| author | Mohr, Stephanie Elizabeth, 1971- |
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| contents | Maps -- Change -- Communication -- Size -- Direction -- Difference -- Defenses -- Behavior -- Coordination -- Continuity. |
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| publisher | Harvard University Press, |
| record_format | marc |
| spelling | Mohr, Stephanie Elizabeth, 1971- author. https://id.oclc.org/worldcat/entity/E39PBJwRTk8kH4BGBwdCc6TWDq http://id.loc.gov/authorities/names/no2017124050 First in fly : Drosophila research and biological discovery / Stephanie Elizabeth Mohr. Cambridge, Massachusetts : Harvard University Press, 2018. ©2018 1 online resource (xii, 257 pages) : illustrations text txt rdacontent computer c rdamedia online resource cr rdacarrier text file A single species of fly, Drosophila melanogaster, has been the subject of scientific research for more than one hundred years. Why does this tiny insect merit such intense scrutiny? Drosophila's importance as a research organism began with its short life cycle, ability to reproduce in large numbers, and easy-to-see mutant phenotypes. Over time, laboratory investigation revealed surprising similarities between flies and other animals at the level of genes, gene networks, cell interactions, physiology, immunity, and behavior. Like humans, flies learn and remember, fight microbial infection, and slow down as they age. Scientists use Drosophila to investigate complex biological activities in a simple but intact living system. Fly research provides answers to some of the most challenging questions in biology and biomedicine, including how cells transmit signals and form ordered structures, how we can interpret the wealth of human genome data now available, and how we can develop effective treatments for cancer, diabetes, and neurodegenerative diseases. This book notes insights uncovered by investigators using this model organism. The author draws on these "first in fly" findings to introduce fundamental biological concepts gained over the last century and explore how research in the common fruit fly has expanded our understanding of human health and disease.-- Provided by publisher Includes bibliographical references and index. Maps -- Change -- Communication -- Size -- Direction -- Difference -- Defenses -- Behavior -- Coordination -- Continuity. Print version record. In English. Drosophila melanogaster Genetics. Drosophila melanogaster Physiology. Animal models in research. http://id.loc.gov/authorities/subjects/sh85005212 Drosophila melanogaster genetics Drosophila melanogaster physiology Drosophila Proteins Models, Animal Drosophila melanogaster Génétique. Drosophila melanogaster Physiologie. Modèles animaux dans la recherche. SCIENCE Life Sciences Zoology General. bisacsh SCIENCE / Life Sciences / Genetics & Genomics bisacsh Science. eflch Animal models in research fast Drosophila melanogaster Genetics fast Drosophila melanogaster Physiology fast Genetik gnd http://d-nb.info/gnd/4071711-2 Physiologie gnd Taufliege gnd http://d-nb.info/gnd/4078168-9 Tiermodell gnd http://d-nb.info/gnd/4140660-6 Science. ukslc has work: First in fly (Text) https://id.oclc.org/worldcat/entity/E39PCFMqxbchpVwhxVrTDpgjbq https://id.oclc.org/worldcat/ontology/hasWork Print version: Mohr, Stephanie Elizabeth, 1971- First in fly. Cambridge, Massachusetts : Harvard University Press, 2018 9780674971011 (DLC) 2017039271 (OCoLC)1002823697 FWS01 ZDB-4-EBA FWS_PDA_EBA https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=1712993 Volltext |
| spellingShingle | Mohr, Stephanie Elizabeth, 1971- First in fly : Drosophila research and biological discovery / Maps -- Change -- Communication -- Size -- Direction -- Difference -- Defenses -- Behavior -- Coordination -- Continuity. Drosophila melanogaster Genetics. Drosophila melanogaster Physiology. Animal models in research. http://id.loc.gov/authorities/subjects/sh85005212 Drosophila melanogaster genetics Drosophila melanogaster physiology Drosophila Proteins Models, Animal Drosophila melanogaster Génétique. Drosophila melanogaster Physiologie. Modèles animaux dans la recherche. SCIENCE Life Sciences Zoology General. bisacsh SCIENCE / Life Sciences / Genetics & Genomics bisacsh Science. eflch Animal models in research fast Drosophila melanogaster Genetics fast Drosophila melanogaster Physiology fast Genetik gnd http://d-nb.info/gnd/4071711-2 Physiologie gnd Taufliege gnd http://d-nb.info/gnd/4078168-9 Tiermodell gnd http://d-nb.info/gnd/4140660-6 Science. ukslc |
| subject_GND | http://id.loc.gov/authorities/subjects/sh85005212 http://d-nb.info/gnd/4071711-2 http://d-nb.info/gnd/4078168-9 http://d-nb.info/gnd/4140660-6 |
| title | First in fly : Drosophila research and biological discovery / |
| title_auth | First in fly : Drosophila research and biological discovery / |
| title_exact_search | First in fly : Drosophila research and biological discovery / |
| title_full | First in fly : Drosophila research and biological discovery / Stephanie Elizabeth Mohr. |
| title_fullStr | First in fly : Drosophila research and biological discovery / Stephanie Elizabeth Mohr. |
| title_full_unstemmed | First in fly : Drosophila research and biological discovery / Stephanie Elizabeth Mohr. |
| title_short | First in fly : |
| title_sort | first in fly drosophila research and biological discovery |
| title_sub | Drosophila research and biological discovery / |
| topic | Drosophila melanogaster Genetics. Drosophila melanogaster Physiology. Animal models in research. http://id.loc.gov/authorities/subjects/sh85005212 Drosophila melanogaster genetics Drosophila melanogaster physiology Drosophila Proteins Models, Animal Drosophila melanogaster Génétique. Drosophila melanogaster Physiologie. Modèles animaux dans la recherche. SCIENCE Life Sciences Zoology General. bisacsh SCIENCE / Life Sciences / Genetics & Genomics bisacsh Science. eflch Animal models in research fast Drosophila melanogaster Genetics fast Drosophila melanogaster Physiology fast Genetik gnd http://d-nb.info/gnd/4071711-2 Physiologie gnd Taufliege gnd http://d-nb.info/gnd/4078168-9 Tiermodell gnd http://d-nb.info/gnd/4140660-6 Science. ukslc |
| topic_facet | Drosophila melanogaster Genetics. Drosophila melanogaster Physiology. Animal models in research. Drosophila melanogaster genetics Drosophila melanogaster physiology Drosophila Proteins Models, Animal Drosophila melanogaster Génétique. Drosophila melanogaster Physiologie. Modèles animaux dans la recherche. SCIENCE Life Sciences Zoology General. SCIENCE / Life Sciences / Genetics & Genomics Science. Animal models in research Drosophila melanogaster Genetics Drosophila melanogaster Physiology Genetik Physiologie Taufliege Tiermodell |
| url | https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=1712993 |
| work_keys_str_mv | AT mohrstephanieelizabeth firstinflydrosophilaresearchandbiologicaldiscovery |