Silica nanoparticles as drug delivery system for immunomodulator GMDP /:
The development of nanosystems for topical drug delivery to target cells is a promising tool to improve the drug therapeutic index. Transport systems can be designed to control the dispatch of the loaded drug to target areas, increasing its local concentration and bioavailability, while prolonging i...
Gespeichert in:
| Weitere Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
New York, N.Y. : [New York, N.Y.] (222 East 46th Street, New York, NY 10017) :
ASME ; Momentum Press,
2012.
|
| Schriftenreihe: | Biomedical & nanomedical technologies.
|
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Zusammenfassung: | The development of nanosystems for topical drug delivery to target cells is a promising tool to improve the drug therapeutic index. Transport systems can be designed to control the dispatch of the loaded drug to target areas, increasing its local concentration and bioavailability, while prolonging its retention, half-life and effectiveness. Therefore, such "smart" nanodevices are able to change radically the practice of therapy for a variety of diseases and disorders. The purpose of this book is to present the recent research development of nanoparticulate delivery systems for immune modulating agent, glucosaminyl muramyldipeptides (N-acetylglucosaminyl-Nacetylmuramyl- L-alanyl-D-isoglutamine) or GMDP, which is the main component of bacterial wall with known target of action through NOD2 receptors, with an overlook to their applications for treatment of endometriosis, which often results in infertility. Silica-based nanoparticles have generated a significant amount of interest because of their inherent properties. |
| Beschreibung: | Title from PDF title page (viewed on September 27, 2012). |
| Beschreibung: | 1 online resource (x, 69 pages) : illustrations, digital file |
| Bibliographie: | Includes bibliographical references (pages 59-69). |
| ISBN: | 9781606503959 1606503952 1606504215 9781606504215 |
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| 245 | 0 | 0 | |a Silica nanoparticles as drug delivery system for immunomodulator GMDP / |c E.V. Parfenyuk [and others]. |
| 260 | |a New York, N.Y. : |b ASME ; |a [New York, N.Y.] (222 East 46th Street, New York, NY 10017) : |b Momentum Press, |c 2012. | ||
| 300 | |a 1 online resource (x, 69 pages) : |b illustrations, digital file | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 490 | 1 | |a Biomedical and nanomedical technologies | |
| 500 | |a Title from PDF title page (viewed on September 27, 2012). | ||
| 504 | |a Includes bibliographical references (pages 59-69). | ||
| 505 | 0 | |a Introduction. | |
| 505 | 8 | |a 1. Drug delivery nanosystems as a promising area of modern chemistry and medicine. Silica nanoparticles as potential drug carriers. | |
| 505 | 8 | |a 2. Syntheses of mesoporous silica materials -- 2.1 Syntheses of unmodified silica materials -- 2.2 Synthesis of modified silica materials. | |
| 505 | 8 | |a 3. Characterization of silica materials as potential carriers for GMDP. -- 3.1 Characterization of silica materials via FTIR spectroscopy -- 3.2 Characterization of silica materials via nitrogen adsorption-desorption measurements -- 3.3 Particle size of silica materials -- 3.4 Characterization of silica materials via small angle x-ray scattering (SAXS) -- 3.5 Adsorption properties of silica materials -- 3.6 DSC study of composites of model protein with silica materials -- 3.7 Calorimetric study of adsorption of model protein on silica materials -- 3.8 Preparation of silica nanoparticle suspensions. | |
| 505 | 8 | |a 4. Interaction of silica nanoparticles with immune system cells -- 4.1 Intensity of different silica nanoparticles uptake by immune cells -- 4.2 Influence of silica nanoparticles on parameters of functional activity of peritoneal macrophages. | |
| 505 | 8 | |a 5. Peritoneal macrophages of women with endometriosis as a possible target for immunomodulatory drugs -- 5.1 Impairment of peritoneal macrophage function at endometriosis -- 5.2 Influence of glucosaminyl muramyldipeptide upon functional activity of peritoneal macrophages of women with endometriosis. | |
| 505 | 8 | |a 6. Effectiveness of different types of silica nanoparticles as drug carriers for topical delivery of GMDP into peritoneal macrophages of women with endometriosis -- 6.1 Immobilization of GMDP on silica nanoparticles -- 6.2 Comparative study of the effects of free GMDP and GMD immobilized on silica nanoparticles on the functional state of peritoneal macrophages. | |
| 505 | 8 | |a References. | |
| 520 | 3 | |a The development of nanosystems for topical drug delivery to target cells is a promising tool to improve the drug therapeutic index. Transport systems can be designed to control the dispatch of the loaded drug to target areas, increasing its local concentration and bioavailability, while prolonging its retention, half-life and effectiveness. Therefore, such "smart" nanodevices are able to change radically the practice of therapy for a variety of diseases and disorders. The purpose of this book is to present the recent research development of nanoparticulate delivery systems for immune modulating agent, glucosaminyl muramyldipeptides (N-acetylglucosaminyl-Nacetylmuramyl- L-alanyl-D-isoglutamine) or GMDP, which is the main component of bacterial wall with known target of action through NOD2 receptors, with an overlook to their applications for treatment of endometriosis, which often results in infertility. Silica-based nanoparticles have generated a significant amount of interest because of their inherent properties. | |
| 650 | 0 | |a Drug delivery systems. |0 http://id.loc.gov/authorities/subjects/sh88007108 | |
| 650 | 0 | |a Nanosilicon. |0 http://id.loc.gov/authorities/subjects/sh2008000719 | |
| 650 | 0 | |a Immunological adjuvants. |0 http://id.loc.gov/authorities/subjects/sh85000895 | |
| 650 | 0 | |a Nanomedicine. |0 http://id.loc.gov/authorities/subjects/sh2007008651 | |
| 650 | 0 | |a Nanoparticles. |0 http://id.loc.gov/authorities/subjects/sh85089689 | |
| 650 | 0 | |a Endometriosis |x Treatment. | |
| 650 | 0 | |a Nanotechnology. |0 http://id.loc.gov/authorities/subjects/sh91001490 | |
| 650 | 0 | |a Silicon. |0 http://id.loc.gov/authorities/subjects/sh85122512 | |
| 650 | 2 | |a Adjuvants, Immunologic | |
| 650 | 2 | |a Drug Delivery Systems | |
| 650 | 2 | |a Endometriosis |x therapy | |
| 650 | 2 | |a Nanomedicine | |
| 650 | 2 | |a Nanoparticles | |
| 650 | 2 | |a Silicon | |
| 650 | 2 | |a Nanotechnology |0 https://id.nlm.nih.gov/mesh/D036103 | |
| 650 | 6 | |a Systèmes d'administration de médicaments. | |
| 650 | 6 | |a Nanosilicium. | |
| 650 | 6 | |a Adjuvants immunologiques. | |
| 650 | 6 | |a Nanoparticules. | |
| 650 | 6 | |a Endométriose |x Traitement. | |
| 650 | 6 | |a Nanomédecine. | |
| 650 | 6 | |a Silicium. | |
| 650 | 6 | |a Nanotechnologie. | |
| 650 | 7 | |a silicon. |2 aat | |
| 650 | 7 | |a MEDICAL |x Pharmacology. |2 bisacsh | |
| 650 | 7 | |a Silicon |2 fast | |
| 650 | 7 | |a Nanotechnology |2 fast | |
| 650 | 7 | |a Drug delivery systems |2 fast | |
| 650 | 7 | |a Endometriosis |x Treatment |2 fast | |
| 650 | 7 | |a Immunological adjuvants |2 fast | |
| 650 | 7 | |a Nanomedicine |2 fast | |
| 650 | 7 | |a Nanoparticles |2 fast | |
| 650 | 7 | |a Nanosilicon |2 fast | |
| 653 | |a Mesoporous silica | ||
| 653 | |a nanoparticles | ||
| 653 | |a sol-gel synthesis | ||
| 653 | |a surface functionalization | ||
| 653 | |a glucosaminyl muramyldipeptide | ||
| 653 | |a endometriosis | ||
| 653 | |a drug delivery system | ||
| 653 | |a drug immobilization | ||
| 653 | |a blood lymphocytes | ||
| 653 | |a peritoneal macrophages | ||
| 653 | |a scavenger receptors | ||
| 653 | |a functional activity of the immune cells | ||
| 700 | 1 | |a Parfenyuk, E. V. | |
| 776 | 0 | 8 | |i Print version: |z 0791860027 |z 9780791860021 |
| 830 | 0 | |a Biomedical & nanomedical technologies. |0 http://id.loc.gov/authorities/names/n2013180695 | |
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Datensatz im Suchindex
| DE-BY-FWS_katkey | ZDB-4-EBA-ocn811246552 |
|---|---|
| _version_ | 1816882208092192768 |
| adam_text | |
| any_adam_object | |
| author2 | Parfenyuk, E. V. |
| author2_role | |
| author2_variant | e v p ev evp |
| author_facet | Parfenyuk, E. V. |
| author_sort | Parfenyuk, E. V. |
| building | Verbundindex |
| bvnumber | localFWS |
| callnumber-first | R - Medicine |
| callnumber-label | RS201 |
| callnumber-raw | RS201.N35 S566 2012 |
| callnumber-search | RS201.N35 S566 2012 |
| callnumber-sort | RS 3201 N35 S566 42012 |
| callnumber-subject | RS - Pharmacy |
| collection | ZDB-4-EBA |
| contents | Introduction. 1. Drug delivery nanosystems as a promising area of modern chemistry and medicine. Silica nanoparticles as potential drug carriers. 2. Syntheses of mesoporous silica materials -- 2.1 Syntheses of unmodified silica materials -- 2.2 Synthesis of modified silica materials. 3. Characterization of silica materials as potential carriers for GMDP. -- 3.1 Characterization of silica materials via FTIR spectroscopy -- 3.2 Characterization of silica materials via nitrogen adsorption-desorption measurements -- 3.3 Particle size of silica materials -- 3.4 Characterization of silica materials via small angle x-ray scattering (SAXS) -- 3.5 Adsorption properties of silica materials -- 3.6 DSC study of composites of model protein with silica materials -- 3.7 Calorimetric study of adsorption of model protein on silica materials -- 3.8 Preparation of silica nanoparticle suspensions. 4. Interaction of silica nanoparticles with immune system cells -- 4.1 Intensity of different silica nanoparticles uptake by immune cells -- 4.2 Influence of silica nanoparticles on parameters of functional activity of peritoneal macrophages. 5. Peritoneal macrophages of women with endometriosis as a possible target for immunomodulatory drugs -- 5.1 Impairment of peritoneal macrophage function at endometriosis -- 5.2 Influence of glucosaminyl muramyldipeptide upon functional activity of peritoneal macrophages of women with endometriosis. 6. Effectiveness of different types of silica nanoparticles as drug carriers for topical delivery of GMDP into peritoneal macrophages of women with endometriosis -- 6.1 Immobilization of GMDP on silica nanoparticles -- 6.2 Comparative study of the effects of free GMDP and GMD immobilized on silica nanoparticles on the functional state of peritoneal macrophages. References. |
| ctrlnum | (OCoLC)811246552 |
| dewey-full | 615.6 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 615 - Pharmacology and therapeutics |
| dewey-raw | 615.6 |
| dewey-search | 615.6 |
| dewey-sort | 3615.6 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| format | Electronic eBook |
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| id | ZDB-4-EBA-ocn811246552 |
| illustrated | Illustrated |
| indexdate | 2024-11-27T13:24:57Z |
| institution | BVB |
| isbn | 9781606503959 1606503952 1606504215 9781606504215 |
| language | English |
| oclc_num | 811246552 |
| open_access_boolean | |
| owner | MAIN DE-863 DE-BY-FWS |
| owner_facet | MAIN DE-863 DE-BY-FWS |
| physical | 1 online resource (x, 69 pages) : illustrations, digital file |
| psigel | ZDB-4-EBA |
| publishDate | 2012 |
| publishDateSearch | 2012 |
| publishDateSort | 2012 |
| publisher | ASME ; Momentum Press, |
| record_format | marc |
| series | Biomedical & nanomedical technologies. |
| series2 | Biomedical and nanomedical technologies |
| spelling | Silica nanoparticles as drug delivery system for immunomodulator GMDP / E.V. Parfenyuk [and others]. New York, N.Y. : ASME ; [New York, N.Y.] (222 East 46th Street, New York, NY 10017) : Momentum Press, 2012. 1 online resource (x, 69 pages) : illustrations, digital file text txt rdacontent computer c rdamedia online resource cr rdacarrier Biomedical and nanomedical technologies Title from PDF title page (viewed on September 27, 2012). Includes bibliographical references (pages 59-69). Introduction. 1. Drug delivery nanosystems as a promising area of modern chemistry and medicine. Silica nanoparticles as potential drug carriers. 2. Syntheses of mesoporous silica materials -- 2.1 Syntheses of unmodified silica materials -- 2.2 Synthesis of modified silica materials. 3. Characterization of silica materials as potential carriers for GMDP. -- 3.1 Characterization of silica materials via FTIR spectroscopy -- 3.2 Characterization of silica materials via nitrogen adsorption-desorption measurements -- 3.3 Particle size of silica materials -- 3.4 Characterization of silica materials via small angle x-ray scattering (SAXS) -- 3.5 Adsorption properties of silica materials -- 3.6 DSC study of composites of model protein with silica materials -- 3.7 Calorimetric study of adsorption of model protein on silica materials -- 3.8 Preparation of silica nanoparticle suspensions. 4. Interaction of silica nanoparticles with immune system cells -- 4.1 Intensity of different silica nanoparticles uptake by immune cells -- 4.2 Influence of silica nanoparticles on parameters of functional activity of peritoneal macrophages. 5. Peritoneal macrophages of women with endometriosis as a possible target for immunomodulatory drugs -- 5.1 Impairment of peritoneal macrophage function at endometriosis -- 5.2 Influence of glucosaminyl muramyldipeptide upon functional activity of peritoneal macrophages of women with endometriosis. 6. Effectiveness of different types of silica nanoparticles as drug carriers for topical delivery of GMDP into peritoneal macrophages of women with endometriosis -- 6.1 Immobilization of GMDP on silica nanoparticles -- 6.2 Comparative study of the effects of free GMDP and GMD immobilized on silica nanoparticles on the functional state of peritoneal macrophages. References. The development of nanosystems for topical drug delivery to target cells is a promising tool to improve the drug therapeutic index. Transport systems can be designed to control the dispatch of the loaded drug to target areas, increasing its local concentration and bioavailability, while prolonging its retention, half-life and effectiveness. Therefore, such "smart" nanodevices are able to change radically the practice of therapy for a variety of diseases and disorders. The purpose of this book is to present the recent research development of nanoparticulate delivery systems for immune modulating agent, glucosaminyl muramyldipeptides (N-acetylglucosaminyl-Nacetylmuramyl- L-alanyl-D-isoglutamine) or GMDP, which is the main component of bacterial wall with known target of action through NOD2 receptors, with an overlook to their applications for treatment of endometriosis, which often results in infertility. Silica-based nanoparticles have generated a significant amount of interest because of their inherent properties. Drug delivery systems. http://id.loc.gov/authorities/subjects/sh88007108 Nanosilicon. http://id.loc.gov/authorities/subjects/sh2008000719 Immunological adjuvants. http://id.loc.gov/authorities/subjects/sh85000895 Nanomedicine. http://id.loc.gov/authorities/subjects/sh2007008651 Nanoparticles. http://id.loc.gov/authorities/subjects/sh85089689 Endometriosis Treatment. Nanotechnology. http://id.loc.gov/authorities/subjects/sh91001490 Silicon. http://id.loc.gov/authorities/subjects/sh85122512 Adjuvants, Immunologic Drug Delivery Systems Endometriosis therapy Nanomedicine Nanoparticles Silicon Nanotechnology https://id.nlm.nih.gov/mesh/D036103 Systèmes d'administration de médicaments. Nanosilicium. Adjuvants immunologiques. Nanoparticules. Endométriose Traitement. Nanomédecine. Silicium. Nanotechnologie. silicon. aat MEDICAL Pharmacology. bisacsh Silicon fast Nanotechnology fast Drug delivery systems fast Endometriosis Treatment fast Immunological adjuvants fast Nanomedicine fast Nanoparticles fast Nanosilicon fast Mesoporous silica nanoparticles sol-gel synthesis surface functionalization glucosaminyl muramyldipeptide endometriosis drug delivery system drug immobilization blood lymphocytes peritoneal macrophages scavenger receptors functional activity of the immune cells Parfenyuk, E. V. Print version: 0791860027 9780791860021 Biomedical & nanomedical technologies. http://id.loc.gov/authorities/names/n2013180695 FWS01 ZDB-4-EBA FWS_PDA_EBA https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=501125 Volltext |
| spellingShingle | Silica nanoparticles as drug delivery system for immunomodulator GMDP / Biomedical & nanomedical technologies. Introduction. 1. Drug delivery nanosystems as a promising area of modern chemistry and medicine. Silica nanoparticles as potential drug carriers. 2. Syntheses of mesoporous silica materials -- 2.1 Syntheses of unmodified silica materials -- 2.2 Synthesis of modified silica materials. 3. Characterization of silica materials as potential carriers for GMDP. -- 3.1 Characterization of silica materials via FTIR spectroscopy -- 3.2 Characterization of silica materials via nitrogen adsorption-desorption measurements -- 3.3 Particle size of silica materials -- 3.4 Characterization of silica materials via small angle x-ray scattering (SAXS) -- 3.5 Adsorption properties of silica materials -- 3.6 DSC study of composites of model protein with silica materials -- 3.7 Calorimetric study of adsorption of model protein on silica materials -- 3.8 Preparation of silica nanoparticle suspensions. 4. Interaction of silica nanoparticles with immune system cells -- 4.1 Intensity of different silica nanoparticles uptake by immune cells -- 4.2 Influence of silica nanoparticles on parameters of functional activity of peritoneal macrophages. 5. Peritoneal macrophages of women with endometriosis as a possible target for immunomodulatory drugs -- 5.1 Impairment of peritoneal macrophage function at endometriosis -- 5.2 Influence of glucosaminyl muramyldipeptide upon functional activity of peritoneal macrophages of women with endometriosis. 6. Effectiveness of different types of silica nanoparticles as drug carriers for topical delivery of GMDP into peritoneal macrophages of women with endometriosis -- 6.1 Immobilization of GMDP on silica nanoparticles -- 6.2 Comparative study of the effects of free GMDP and GMD immobilized on silica nanoparticles on the functional state of peritoneal macrophages. References. Drug delivery systems. http://id.loc.gov/authorities/subjects/sh88007108 Nanosilicon. http://id.loc.gov/authorities/subjects/sh2008000719 Immunological adjuvants. http://id.loc.gov/authorities/subjects/sh85000895 Nanomedicine. http://id.loc.gov/authorities/subjects/sh2007008651 Nanoparticles. http://id.loc.gov/authorities/subjects/sh85089689 Endometriosis Treatment. Nanotechnology. http://id.loc.gov/authorities/subjects/sh91001490 Silicon. http://id.loc.gov/authorities/subjects/sh85122512 Adjuvants, Immunologic Drug Delivery Systems Endometriosis therapy Nanomedicine Nanoparticles Silicon Nanotechnology https://id.nlm.nih.gov/mesh/D036103 Systèmes d'administration de médicaments. Nanosilicium. Adjuvants immunologiques. Nanoparticules. Endométriose Traitement. Nanomédecine. Silicium. Nanotechnologie. silicon. aat MEDICAL Pharmacology. bisacsh Silicon fast Nanotechnology fast Drug delivery systems fast Endometriosis Treatment fast Immunological adjuvants fast Nanomedicine fast Nanoparticles fast Nanosilicon fast |
| subject_GND | http://id.loc.gov/authorities/subjects/sh88007108 http://id.loc.gov/authorities/subjects/sh2008000719 http://id.loc.gov/authorities/subjects/sh85000895 http://id.loc.gov/authorities/subjects/sh2007008651 http://id.loc.gov/authorities/subjects/sh85089689 http://id.loc.gov/authorities/subjects/sh91001490 http://id.loc.gov/authorities/subjects/sh85122512 https://id.nlm.nih.gov/mesh/D036103 |
| title | Silica nanoparticles as drug delivery system for immunomodulator GMDP / |
| title_auth | Silica nanoparticles as drug delivery system for immunomodulator GMDP / |
| title_exact_search | Silica nanoparticles as drug delivery system for immunomodulator GMDP / |
| title_full | Silica nanoparticles as drug delivery system for immunomodulator GMDP / E.V. Parfenyuk [and others]. |
| title_fullStr | Silica nanoparticles as drug delivery system for immunomodulator GMDP / E.V. Parfenyuk [and others]. |
| title_full_unstemmed | Silica nanoparticles as drug delivery system for immunomodulator GMDP / E.V. Parfenyuk [and others]. |
| title_short | Silica nanoparticles as drug delivery system for immunomodulator GMDP / |
| title_sort | silica nanoparticles as drug delivery system for immunomodulator gmdp |
| topic | Drug delivery systems. http://id.loc.gov/authorities/subjects/sh88007108 Nanosilicon. http://id.loc.gov/authorities/subjects/sh2008000719 Immunological adjuvants. http://id.loc.gov/authorities/subjects/sh85000895 Nanomedicine. http://id.loc.gov/authorities/subjects/sh2007008651 Nanoparticles. http://id.loc.gov/authorities/subjects/sh85089689 Endometriosis Treatment. Nanotechnology. http://id.loc.gov/authorities/subjects/sh91001490 Silicon. http://id.loc.gov/authorities/subjects/sh85122512 Adjuvants, Immunologic Drug Delivery Systems Endometriosis therapy Nanomedicine Nanoparticles Silicon Nanotechnology https://id.nlm.nih.gov/mesh/D036103 Systèmes d'administration de médicaments. Nanosilicium. Adjuvants immunologiques. Nanoparticules. Endométriose Traitement. Nanomédecine. Silicium. Nanotechnologie. silicon. aat MEDICAL Pharmacology. bisacsh Silicon fast Nanotechnology fast Drug delivery systems fast Endometriosis Treatment fast Immunological adjuvants fast Nanomedicine fast Nanoparticles fast Nanosilicon fast |
| topic_facet | Drug delivery systems. Nanosilicon. Immunological adjuvants. Nanomedicine. Nanoparticles. Endometriosis Treatment. Nanotechnology. Silicon. Adjuvants, Immunologic Drug Delivery Systems Endometriosis therapy Nanomedicine Nanoparticles Silicon Nanotechnology Systèmes d'administration de médicaments. Nanosilicium. Adjuvants immunologiques. Nanoparticules. Endométriose Traitement. Nanomédecine. Silicium. Nanotechnologie. silicon. MEDICAL Pharmacology. Drug delivery systems Endometriosis Treatment Immunological adjuvants Nanosilicon |
| url | https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=501125 |
| work_keys_str_mv | AT parfenyukev silicananoparticlesasdrugdeliverysystemforimmunomodulatorgmdp |