Recent advances in prostate cancer :: basic science discoveries and clinical advances /
This book effectively summarizes our knowledge of recent advances in prostate cancer. It focuses on our state-of-the-art understanding of risk factors, prevention, detection, prognosis and treatment of prostate cancer and identifies basic science findings that are being translated into clinical prac...
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Weitere Verfasser: | |
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Singapore :
World Scientific Publishing,
2011.
|
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Zusammenfassung: | This book effectively summarizes our knowledge of recent advances in prostate cancer. It focuses on our state-of-the-art understanding of risk factors, prevention, detection, prognosis and treatment of prostate cancer and identifies basic science findings that are being translated into clinical practice. In addition, the book singles out key areas of research that have potential for clinical translation. Both basic scientists and clinicians will be invited to provide up-to-date reviews in each area of prostate cancer. During the last decade the pace of clinical discovery and the scientific advances in prostate cancer have been very rapid. For instance, currently there are more than 100 drugs in the pharmaceutical pipeline that have the potential for clinical management of prostate cancer. Therefore, it has been very difficult for clinicians and basic scientists to keep pace with the field as a whole. Recently, some of these discoveries are already having an impact on clinical practice. For example, the discovery of the androgen receptor gene amplification in prostate cancer has led to the development of a "super-antiandrogen", which is being tested in clinical trials. Also, recent knowledge of androgen synthesis in prostate cancer cells has led to clinical trials with steroid-metabolism inhibitors. Finally, robotic surgery has also dramatically changed clinical practice. Thus, this important book serves to provide readers with a one-stop overview of the field of prostate cancer research and its translation into the clinical arena |
| Beschreibung: | 1 online resource (xxv, 671 pages :) |
| Bibliographie: | Includes bibliographical references and index. |
| ISBN: | 9789814329460 9814329460 1283433559 9781283433556 |
Internformat
MARC
| LEADER | 00000cam a2200000 a 4500 | ||
|---|---|---|---|
| 001 | ZDB-4-EBA-ocn775361436 | ||
| 003 | OCoLC | ||
| 005 | 20240705115654.0 | ||
| 006 | m o d | ||
| 007 | cr cnu---unuuu | ||
| 008 | 120206s2011 si a ob 001 0 eng d | ||
| 010 | |z 2011499696 | ||
| 040 | |a N$T |b eng |e pn |c N$T |d E7B |d YDXCP |d OCLCQ |d OCLCF |d NLGGC |d OCLCO |d IDEBK |d CDX |d EBLCP |d MHW |d UKDOC |d OCLCQ |d OCLCO |d OCLCQ |d D6H |d AGLDB |d OCLCO |d OCLCQ |d VTS |d TOF |d AU@ |d OCLCO |d REC |d STF |d UKAHL |d OCLCQ |d LEAUB |d OCLCQ |d AJS |d OCLCQ |d OCLCO |d OCLCQ |d OCLCO |d INARC |d OCLCL |d SXB |d OCLCQ | ||
| 016 | 7 | |a 015776925 |2 Uk | |
| 019 | |a 778314561 |a 817056689 |a 824106802 |a 858228208 |a 956666693 |a 1086518970 |a 1412665037 | ||
| 020 | |a 9789814329460 |q (electronic bk.) | ||
| 020 | |a 9814329460 |q (electronic bk.) | ||
| 020 | |a 1283433559 | ||
| 020 | |a 9781283433556 | ||
| 020 | |z 9789814329453 | ||
| 020 | |z 9814329452 | ||
| 035 | |a (OCoLC)775361436 |z (OCoLC)778314561 |z (OCoLC)817056689 |z (OCoLC)824106802 |z (OCoLC)858228208 |z (OCoLC)956666693 |z (OCoLC)1086518970 |z (OCoLC)1412665037 | ||
| 050 | 4 | |a RC280.P7 |b R43 2011eb | |
| 060 | 4 | |a 2011 K-596 | |
| 060 | 4 | |a WJ 762 | |
| 072 | 7 | |a HEA |x 039030 |2 bisacsh | |
| 072 | 7 | |a MED |x 062000 |2 bisacsh | |
| 072 | 7 | |a MJCL |2 bicssc | |
| 082 | 7 | |a 616.99/463 |2 23 | |
| 049 | |a MAIN | ||
| 100 | 1 | |a Tindall, Donald. | |
| 245 | 1 | 0 | |a Recent advances in prostate cancer : |b basic science discoveries and clinical advances / |c Donald J. Tindall and Peter T. Scardino. |
| 260 | |a Singapore : |b World Scientific Publishing, |c 2011. | ||
| 300 | |a 1 online resource (xxv, 671 pages :) | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 504 | |a Includes bibliographical references and index. | ||
| 588 | 0 | |a Print version record. | |
| 505 | 0 | |a Contributors; Preface; Chapter 1 Pathology of Prostate Lawrence True and Funda Vakar-Lopez; Introduction; Prostate Anatomy; Prostate "Capsule"; Zones of the Prostate; Cell Types of the Prostate; Benign Prostatic Hypertrophy (BPH); Inflammation; Granulomatous Prostatitis; Chronic Prostatitis; Pre-Neoplastic Lesions; Prostatic Intraepithelial Neoplasia (PIN); Other Candidate Pre-Neoplastic Lesions; Prostate Carcinoma; Diagnosis of Prostate Cancer; Differential Diagnostic Considerations; Grading Prostate Carcinoma; Tertiary Gleason pattern; Percentage of Gleason patterns. | |
| 505 | 8 | |a Grade progressionSpindle Cell Lesions; Non-Prostate Spindle Cell Lesions; Prostate Spindle Cell Lesions; Sarcoma of Prostate; Carcinosarcoma (Sarcomatoid Carcinoma) of Prostate; Pathology of Non-Surgical Therapy; Radiation Therapy; Androgen Deprivation (Blockade) Therapy; Neoadjuvant Therapy; Recommendations for Pathology Reports; Needle Biopsy Reports; Radical Prostatectomy Reports; Surgical margin; Extraprostatic extension; Lymph node dissection; Tissue Biomarkers; Future Trends; References; Chapter 2 Genetic Basis for Prostate Cancer Stacy Loeb and William B. Isaacs; Introduction. | |
| 505 | 8 | |a Family-Based StudiesGenome-Wide Association Studies; Future Directions; Conclusions; References; Chapter 3 Androgen Receptor Converts from a Growth Suppressor in the Normal Prostate to an Oncogene in Prostate Cancer Donald J. Vander Griend and John T. Isaacs; Introduction; Androgen Receptor Suppresses the Growth of Normal Prostate Epithelial Cells; Androgen Receptor Functions as an Oncogene in Prostate Cancer; Clinical Implications of AR Conversion from a Growth Suppressor to an Oncogene; Loss of AR-Mediated Growth Suppression Without Gaining Oncogenic Ability; Acknowledgments; References. | |
| 505 | 8 | |a Chapter 4 Etiology: Role of ETS Factor Gene Fusions Jianghua Wang and Michael IttmannIntroduction; ETS Transcription Factor Gene Fusions in Prostate Cancer; Structure and Transcription of the TMPRSS2/ERG Fusion Gene; Origin of the TMPRSS2/ERG Fusion Gene; Alternative Splicing of the TMPRSS2/ERG Fusion Transcript; Pathological Correlations; The ETS Transcription Factor Gene Family; Biological Activities of the ERG and T/E Fusion Gene Protein; Association of T/E Fusion Gene Expression with Global Gene Expression and Copy Number Alterations in Prostate Cancer. | |
| 505 | 8 | |a Genetics of TMPRSS2/ERG Prostate CancerClinical Implications of the TMPRSS2/ERG Fusion Gene; Summary; References; Chapter 5 Etiology of Prostate Cancer: Role of Inflammation William G. Nelson, Angelo M. DeMarzo and Srinivasan Yegnasubramanian; Introduction; Inflammation in the Human Prostate and Prostate Cancer; Sex Steroid Hormones and Inflammation in the Prostate; Infections and Inflammation in the Prostate; Inflammation and Inherited Susceptibility to Prostate Cancer; The Diet and Inflammation in the Prostate; Inflammation and the Molecular Pathogenesis of Prostate Cancer. | |
| 520 | |a This book effectively summarizes our knowledge of recent advances in prostate cancer. It focuses on our state-of-the-art understanding of risk factors, prevention, detection, prognosis and treatment of prostate cancer and identifies basic science findings that are being translated into clinical practice. In addition, the book singles out key areas of research that have potential for clinical translation. Both basic scientists and clinicians will be invited to provide up-to-date reviews in each area of prostate cancer. During the last decade the pace of clinical discovery and the scientific advances in prostate cancer have been very rapid. For instance, currently there are more than 100 drugs in the pharmaceutical pipeline that have the potential for clinical management of prostate cancer. Therefore, it has been very difficult for clinicians and basic scientists to keep pace with the field as a whole. Recently, some of these discoveries are already having an impact on clinical practice. For example, the discovery of the androgen receptor gene amplification in prostate cancer has led to the development of a "super-antiandrogen", which is being tested in clinical trials. Also, recent knowledge of androgen synthesis in prostate cancer cells has led to clinical trials with steroid-metabolism inhibitors. Finally, robotic surgery has also dramatically changed clinical practice. Thus, this important book serves to provide readers with a one-stop overview of the field of prostate cancer research and its translation into the clinical arena | ||
| 650 | 0 | |a Prostate |x Cancer. |0 http://id.loc.gov/authorities/subjects/sh85107606 | |
| 650 | 0 | |a Prostate |x Cancer |x Diagnosis. | |
| 650 | 0 | |a Prostate |x Cancer |x Treatment. | |
| 650 | 1 | 2 | |a Prostatic Neoplasms |x diagnosis |0 https://id.nlm.nih.gov/mesh/D011471Q000175 |
| 650 | 2 | 2 | |a Prostatic Neoplasms |x therapy |0 https://id.nlm.nih.gov/mesh/D011471Q000628 |
| 650 | 2 | |a Prostatic Neoplasms |0 https://id.nlm.nih.gov/mesh/D011471 | |
| 650 | 6 | |a Prostate |x Cancer. | |
| 650 | 6 | |a Prostate |x Cancer |x Traitement. | |
| 650 | 7 | |a HEALTH & FITNESS |x Diseases |x Cancer. |2 bisacsh | |
| 650 | 7 | |a MEDICAL |x Oncology. |2 bisacsh | |
| 650 | 7 | |a Prostate |x Cancer |2 fast | |
| 650 | 7 | |a Prostate |x Cancer |x Diagnosis |2 fast | |
| 650 | 7 | |a Prostate |x Cancer |x Treatment |2 fast | |
| 700 | 1 | |a Scardino, Peter T. | |
| 758 | |i has work: |a Recent advances in prostate cancer (Text) |1 https://id.oclc.org/worldcat/entity/E39PCGMjft3JJdWT6kXx6gGJXd |4 https://id.oclc.org/worldcat/ontology/hasWork | ||
| 776 | 0 | 8 | |i Print version: |a Tindall, Donald. |t Recent advances in prostate cancer. |d Singapore : World Scientific Publishing, 2011 |z 9789814329453 |w (DLC) 2011499696 |w (OCoLC)755875175 |
| 856 | 1 | |l FWS01 |p ZDB-4-EBA |q FWS_PDA_EBA |u https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=426401 |3 Volltext | |
| 856 | 1 | |l CBO01 |p ZDB-4-EBA |q FWS_PDA_EBA |u https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=426401 |3 Volltext | |
| 938 | |a 123Library |b 123L |n 52474 | ||
| 938 | |a Askews and Holts Library Services |b ASKH |n AH25565279 | ||
| 938 | |a Coutts Information Services |b COUT |n 23886965 | ||
| 938 | |a ProQuest Ebook Central |b EBLB |n EBL840668 | ||
| 938 | |a ebrary |b EBRY |n ebr10524545 | ||
| 938 | |a EBSCOhost |b EBSC |n 426401 | ||
| 938 | |a ProQuest MyiLibrary Digital eBook Collection |b IDEB |n 343355 | ||
| 938 | |a YBP Library Services |b YANK |n 3754963 | ||
| 938 | |a Internet Archive |b INAR |n isbn_9789814329453 | ||
| 994 | |a 92 |b GEBAY | ||
| 912 | |a ZDB-4-EBA | ||
Datensatz im Suchindex
| DE-BY-FWS_katkey | ZDB-4-EBA-ocn775361436 |
|---|---|
| _version_ | 1813903426750251009 |
| adam_text | |
| any_adam_object | |
| author | Tindall, Donald |
| author2 | Scardino, Peter T. |
| author2_role | |
| author2_variant | p t s pt pts |
| author_facet | Tindall, Donald Scardino, Peter T. |
| author_role | |
| author_sort | Tindall, Donald |
| author_variant | d t dt |
| building | Verbundindex |
| bvnumber | localFWS |
| callnumber-first | R - Medicine |
| callnumber-label | RC280 |
| callnumber-raw | RC280.P7 R43 2011eb |
| callnumber-search | RC280.P7 R43 2011eb |
| callnumber-sort | RC 3280 P7 R43 42011EB |
| callnumber-subject | RC - Internal Medicine |
| collection | ZDB-4-EBA |
| contents | Contributors; Preface; Chapter 1 Pathology of Prostate Lawrence True and Funda Vakar-Lopez; Introduction; Prostate Anatomy; Prostate "Capsule"; Zones of the Prostate; Cell Types of the Prostate; Benign Prostatic Hypertrophy (BPH); Inflammation; Granulomatous Prostatitis; Chronic Prostatitis; Pre-Neoplastic Lesions; Prostatic Intraepithelial Neoplasia (PIN); Other Candidate Pre-Neoplastic Lesions; Prostate Carcinoma; Diagnosis of Prostate Cancer; Differential Diagnostic Considerations; Grading Prostate Carcinoma; Tertiary Gleason pattern; Percentage of Gleason patterns. Grade progressionSpindle Cell Lesions; Non-Prostate Spindle Cell Lesions; Prostate Spindle Cell Lesions; Sarcoma of Prostate; Carcinosarcoma (Sarcomatoid Carcinoma) of Prostate; Pathology of Non-Surgical Therapy; Radiation Therapy; Androgen Deprivation (Blockade) Therapy; Neoadjuvant Therapy; Recommendations for Pathology Reports; Needle Biopsy Reports; Radical Prostatectomy Reports; Surgical margin; Extraprostatic extension; Lymph node dissection; Tissue Biomarkers; Future Trends; References; Chapter 2 Genetic Basis for Prostate Cancer Stacy Loeb and William B. Isaacs; Introduction. Family-Based StudiesGenome-Wide Association Studies; Future Directions; Conclusions; References; Chapter 3 Androgen Receptor Converts from a Growth Suppressor in the Normal Prostate to an Oncogene in Prostate Cancer Donald J. Vander Griend and John T. Isaacs; Introduction; Androgen Receptor Suppresses the Growth of Normal Prostate Epithelial Cells; Androgen Receptor Functions as an Oncogene in Prostate Cancer; Clinical Implications of AR Conversion from a Growth Suppressor to an Oncogene; Loss of AR-Mediated Growth Suppression Without Gaining Oncogenic Ability; Acknowledgments; References. Chapter 4 Etiology: Role of ETS Factor Gene Fusions Jianghua Wang and Michael IttmannIntroduction; ETS Transcription Factor Gene Fusions in Prostate Cancer; Structure and Transcription of the TMPRSS2/ERG Fusion Gene; Origin of the TMPRSS2/ERG Fusion Gene; Alternative Splicing of the TMPRSS2/ERG Fusion Transcript; Pathological Correlations; The ETS Transcription Factor Gene Family; Biological Activities of the ERG and T/E Fusion Gene Protein; Association of T/E Fusion Gene Expression with Global Gene Expression and Copy Number Alterations in Prostate Cancer. Genetics of TMPRSS2/ERG Prostate CancerClinical Implications of the TMPRSS2/ERG Fusion Gene; Summary; References; Chapter 5 Etiology of Prostate Cancer: Role of Inflammation William G. Nelson, Angelo M. DeMarzo and Srinivasan Yegnasubramanian; Introduction; Inflammation in the Human Prostate and Prostate Cancer; Sex Steroid Hormones and Inflammation in the Prostate; Infections and Inflammation in the Prostate; Inflammation and Inherited Susceptibility to Prostate Cancer; The Diet and Inflammation in the Prostate; Inflammation and the Molecular Pathogenesis of Prostate Cancer. |
| ctrlnum | (OCoLC)775361436 |
| dewey-full | 616.99/463 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 616 - Diseases |
| dewey-raw | 616.99/463 |
| dewey-search | 616.99/463 |
| dewey-sort | 3616.99 3463 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| format | Electronic eBook |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>08096cam a2200829 a 4500</leader><controlfield tag="001">ZDB-4-EBA-ocn775361436</controlfield><controlfield tag="003">OCoLC</controlfield><controlfield tag="005">20240705115654.0</controlfield><controlfield tag="006">m o d </controlfield><controlfield tag="007">cr cnu---unuuu</controlfield><controlfield tag="008">120206s2011 si a ob 001 0 eng d</controlfield><datafield tag="010" ind1=" " ind2=" "><subfield code="z"> 2011499696</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">N$T</subfield><subfield code="b">eng</subfield><subfield code="e">pn</subfield><subfield code="c">N$T</subfield><subfield code="d">E7B</subfield><subfield code="d">YDXCP</subfield><subfield code="d">OCLCQ</subfield><subfield code="d">OCLCF</subfield><subfield code="d">NLGGC</subfield><subfield code="d">OCLCO</subfield><subfield code="d">IDEBK</subfield><subfield code="d">CDX</subfield><subfield code="d">EBLCP</subfield><subfield code="d">MHW</subfield><subfield code="d">UKDOC</subfield><subfield code="d">OCLCQ</subfield><subfield code="d">OCLCO</subfield><subfield code="d">OCLCQ</subfield><subfield code="d">D6H</subfield><subfield code="d">AGLDB</subfield><subfield code="d">OCLCO</subfield><subfield code="d">OCLCQ</subfield><subfield code="d">VTS</subfield><subfield code="d">TOF</subfield><subfield code="d">AU@</subfield><subfield code="d">OCLCO</subfield><subfield code="d">REC</subfield><subfield code="d">STF</subfield><subfield code="d">UKAHL</subfield><subfield code="d">OCLCQ</subfield><subfield code="d">LEAUB</subfield><subfield code="d">OCLCQ</subfield><subfield code="d">AJS</subfield><subfield code="d">OCLCQ</subfield><subfield code="d">OCLCO</subfield><subfield code="d">OCLCQ</subfield><subfield code="d">OCLCO</subfield><subfield code="d">INARC</subfield><subfield code="d">OCLCL</subfield><subfield code="d">SXB</subfield><subfield code="d">OCLCQ</subfield></datafield><datafield tag="016" ind1="7" ind2=" "><subfield code="a">015776925</subfield><subfield code="2">Uk</subfield></datafield><datafield tag="019" ind1=" " ind2=" "><subfield code="a">778314561</subfield><subfield code="a">817056689</subfield><subfield code="a">824106802</subfield><subfield code="a">858228208</subfield><subfield code="a">956666693</subfield><subfield code="a">1086518970</subfield><subfield code="a">1412665037</subfield></datafield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9789814329460</subfield><subfield code="q">(electronic bk.)</subfield></datafield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9814329460</subfield><subfield code="q">(electronic bk.)</subfield></datafield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">1283433559</subfield></datafield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9781283433556</subfield></datafield><datafield tag="020" ind1=" " ind2=" "><subfield code="z">9789814329453</subfield></datafield><datafield tag="020" ind1=" " ind2=" "><subfield code="z">9814329452</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)775361436</subfield><subfield code="z">(OCoLC)778314561</subfield><subfield code="z">(OCoLC)817056689</subfield><subfield code="z">(OCoLC)824106802</subfield><subfield code="z">(OCoLC)858228208</subfield><subfield code="z">(OCoLC)956666693</subfield><subfield code="z">(OCoLC)1086518970</subfield><subfield code="z">(OCoLC)1412665037</subfield></datafield><datafield tag="050" ind1=" " ind2="4"><subfield code="a">RC280.P7</subfield><subfield code="b">R43 2011eb</subfield></datafield><datafield tag="060" ind1=" " ind2="4"><subfield code="a">2011 K-596</subfield></datafield><datafield tag="060" ind1=" " ind2="4"><subfield code="a">WJ 762</subfield></datafield><datafield tag="072" ind1=" " ind2="7"><subfield code="a">HEA</subfield><subfield code="x">039030</subfield><subfield code="2">bisacsh</subfield></datafield><datafield tag="072" ind1=" " ind2="7"><subfield code="a">MED</subfield><subfield code="x">062000</subfield><subfield code="2">bisacsh</subfield></datafield><datafield tag="072" ind1=" " ind2="7"><subfield code="a">MJCL</subfield><subfield code="2">bicssc</subfield></datafield><datafield tag="082" ind1="7" ind2=" "><subfield code="a">616.99/463</subfield><subfield code="2">23</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">MAIN</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Tindall, Donald.</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Recent advances in prostate cancer :</subfield><subfield code="b">basic science discoveries and clinical advances /</subfield><subfield code="c">Donald J. Tindall and Peter T. Scardino.</subfield></datafield><datafield tag="260" ind1=" " ind2=" "><subfield code="a">Singapore :</subfield><subfield code="b">World Scientific Publishing,</subfield><subfield code="c">2011.</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 online resource (xxv, 671 pages :)</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">computer</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">online resource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="504" ind1=" " ind2=" "><subfield code="a">Includes bibliographical references and index.</subfield></datafield><datafield tag="588" ind1="0" ind2=" "><subfield code="a">Print version record.</subfield></datafield><datafield tag="505" ind1="0" ind2=" "><subfield code="a">Contributors; Preface; Chapter 1 Pathology of Prostate Lawrence True and Funda Vakar-Lopez; Introduction; Prostate Anatomy; Prostate "Capsule"; Zones of the Prostate; Cell Types of the Prostate; Benign Prostatic Hypertrophy (BPH); Inflammation; Granulomatous Prostatitis; Chronic Prostatitis; Pre-Neoplastic Lesions; Prostatic Intraepithelial Neoplasia (PIN); Other Candidate Pre-Neoplastic Lesions; Prostate Carcinoma; Diagnosis of Prostate Cancer; Differential Diagnostic Considerations; Grading Prostate Carcinoma; Tertiary Gleason pattern; Percentage of Gleason patterns.</subfield></datafield><datafield tag="505" ind1="8" ind2=" "><subfield code="a">Grade progressionSpindle Cell Lesions; Non-Prostate Spindle Cell Lesions; Prostate Spindle Cell Lesions; Sarcoma of Prostate; Carcinosarcoma (Sarcomatoid Carcinoma) of Prostate; Pathology of Non-Surgical Therapy; Radiation Therapy; Androgen Deprivation (Blockade) Therapy; Neoadjuvant Therapy; Recommendations for Pathology Reports; Needle Biopsy Reports; Radical Prostatectomy Reports; Surgical margin; Extraprostatic extension; Lymph node dissection; Tissue Biomarkers; Future Trends; References; Chapter 2 Genetic Basis for Prostate Cancer Stacy Loeb and William B. Isaacs; Introduction.</subfield></datafield><datafield tag="505" ind1="8" ind2=" "><subfield code="a">Family-Based StudiesGenome-Wide Association Studies; Future Directions; Conclusions; References; Chapter 3 Androgen Receptor Converts from a Growth Suppressor in the Normal Prostate to an Oncogene in Prostate Cancer Donald J. Vander Griend and John T. Isaacs; Introduction; Androgen Receptor Suppresses the Growth of Normal Prostate Epithelial Cells; Androgen Receptor Functions as an Oncogene in Prostate Cancer; Clinical Implications of AR Conversion from a Growth Suppressor to an Oncogene; Loss of AR-Mediated Growth Suppression Without Gaining Oncogenic Ability; Acknowledgments; References.</subfield></datafield><datafield tag="505" ind1="8" ind2=" "><subfield code="a">Chapter 4 Etiology: Role of ETS Factor Gene Fusions Jianghua Wang and Michael IttmannIntroduction; ETS Transcription Factor Gene Fusions in Prostate Cancer; Structure and Transcription of the TMPRSS2/ERG Fusion Gene; Origin of the TMPRSS2/ERG Fusion Gene; Alternative Splicing of the TMPRSS2/ERG Fusion Transcript; Pathological Correlations; The ETS Transcription Factor Gene Family; Biological Activities of the ERG and T/E Fusion Gene Protein; Association of T/E Fusion Gene Expression with Global Gene Expression and Copy Number Alterations in Prostate Cancer.</subfield></datafield><datafield tag="505" ind1="8" ind2=" "><subfield code="a">Genetics of TMPRSS2/ERG Prostate CancerClinical Implications of the TMPRSS2/ERG Fusion Gene; Summary; References; Chapter 5 Etiology of Prostate Cancer: Role of Inflammation William G. Nelson, Angelo M. DeMarzo and Srinivasan Yegnasubramanian; Introduction; Inflammation in the Human Prostate and Prostate Cancer; Sex Steroid Hormones and Inflammation in the Prostate; Infections and Inflammation in the Prostate; Inflammation and Inherited Susceptibility to Prostate Cancer; The Diet and Inflammation in the Prostate; Inflammation and the Molecular Pathogenesis of Prostate Cancer.</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">This book effectively summarizes our knowledge of recent advances in prostate cancer. It focuses on our state-of-the-art understanding of risk factors, prevention, detection, prognosis and treatment of prostate cancer and identifies basic science findings that are being translated into clinical practice. In addition, the book singles out key areas of research that have potential for clinical translation. Both basic scientists and clinicians will be invited to provide up-to-date reviews in each area of prostate cancer. During the last decade the pace of clinical discovery and the scientific advances in prostate cancer have been very rapid. For instance, currently there are more than 100 drugs in the pharmaceutical pipeline that have the potential for clinical management of prostate cancer. Therefore, it has been very difficult for clinicians and basic scientists to keep pace with the field as a whole. Recently, some of these discoveries are already having an impact on clinical practice. For example, the discovery of the androgen receptor gene amplification in prostate cancer has led to the development of a "super-antiandrogen", which is being tested in clinical trials. Also, recent knowledge of androgen synthesis in prostate cancer cells has led to clinical trials with steroid-metabolism inhibitors. Finally, robotic surgery has also dramatically changed clinical practice. Thus, this important book serves to provide readers with a one-stop overview of the field of prostate cancer research and its translation into the clinical arena</subfield></datafield><datafield tag="650" ind1=" " ind2="0"><subfield code="a">Prostate</subfield><subfield code="x">Cancer.</subfield><subfield code="0">http://id.loc.gov/authorities/subjects/sh85107606</subfield></datafield><datafield tag="650" ind1=" " ind2="0"><subfield code="a">Prostate</subfield><subfield code="x">Cancer</subfield><subfield code="x">Diagnosis.</subfield></datafield><datafield tag="650" ind1=" " ind2="0"><subfield code="a">Prostate</subfield><subfield code="x">Cancer</subfield><subfield code="x">Treatment.</subfield></datafield><datafield tag="650" ind1="1" ind2="2"><subfield code="a">Prostatic Neoplasms</subfield><subfield code="x">diagnosis</subfield><subfield code="0">https://id.nlm.nih.gov/mesh/D011471Q000175</subfield></datafield><datafield tag="650" ind1="2" ind2="2"><subfield code="a">Prostatic Neoplasms</subfield><subfield code="x">therapy</subfield><subfield code="0">https://id.nlm.nih.gov/mesh/D011471Q000628</subfield></datafield><datafield tag="650" ind1=" " ind2="2"><subfield code="a">Prostatic Neoplasms</subfield><subfield code="0">https://id.nlm.nih.gov/mesh/D011471</subfield></datafield><datafield tag="650" ind1=" " ind2="6"><subfield code="a">Prostate</subfield><subfield code="x">Cancer.</subfield></datafield><datafield tag="650" ind1=" " ind2="6"><subfield code="a">Prostate</subfield><subfield code="x">Cancer</subfield><subfield code="x">Traitement.</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">HEALTH & FITNESS</subfield><subfield code="x">Diseases</subfield><subfield code="x">Cancer.</subfield><subfield code="2">bisacsh</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">MEDICAL</subfield><subfield code="x">Oncology.</subfield><subfield code="2">bisacsh</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Prostate</subfield><subfield code="x">Cancer</subfield><subfield code="2">fast</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Prostate</subfield><subfield code="x">Cancer</subfield><subfield code="x">Diagnosis</subfield><subfield code="2">fast</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Prostate</subfield><subfield code="x">Cancer</subfield><subfield code="x">Treatment</subfield><subfield code="2">fast</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Scardino, Peter T.</subfield></datafield><datafield tag="758" ind1=" " ind2=" "><subfield code="i">has work:</subfield><subfield code="a">Recent advances in prostate cancer (Text)</subfield><subfield code="1">https://id.oclc.org/worldcat/entity/E39PCGMjft3JJdWT6kXx6gGJXd</subfield><subfield code="4">https://id.oclc.org/worldcat/ontology/hasWork</subfield></datafield><datafield tag="776" ind1="0" ind2="8"><subfield code="i">Print version:</subfield><subfield code="a">Tindall, Donald.</subfield><subfield code="t">Recent advances in prostate cancer.</subfield><subfield code="d">Singapore : World Scientific Publishing, 2011</subfield><subfield code="z">9789814329453</subfield><subfield code="w">(DLC) 2011499696</subfield><subfield code="w">(OCoLC)755875175</subfield></datafield><datafield tag="856" ind1="1" ind2=" "><subfield code="l">FWS01</subfield><subfield code="p">ZDB-4-EBA</subfield><subfield code="q">FWS_PDA_EBA</subfield><subfield code="u">https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=426401</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="856" ind1="1" ind2=" "><subfield code="l">CBO01</subfield><subfield code="p">ZDB-4-EBA</subfield><subfield code="q">FWS_PDA_EBA</subfield><subfield code="u">https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=426401</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="938" ind1=" " ind2=" "><subfield code="a">123Library</subfield><subfield code="b">123L</subfield><subfield code="n">52474</subfield></datafield><datafield tag="938" ind1=" " ind2=" "><subfield code="a">Askews and Holts Library Services</subfield><subfield code="b">ASKH</subfield><subfield code="n">AH25565279</subfield></datafield><datafield tag="938" ind1=" " ind2=" "><subfield code="a">Coutts Information Services</subfield><subfield code="b">COUT</subfield><subfield code="n">23886965</subfield></datafield><datafield tag="938" ind1=" " ind2=" "><subfield code="a">ProQuest Ebook Central</subfield><subfield code="b">EBLB</subfield><subfield code="n">EBL840668</subfield></datafield><datafield tag="938" ind1=" " ind2=" "><subfield code="a">ebrary</subfield><subfield code="b">EBRY</subfield><subfield code="n">ebr10524545</subfield></datafield><datafield tag="938" ind1=" " ind2=" "><subfield code="a">EBSCOhost</subfield><subfield code="b">EBSC</subfield><subfield code="n">426401</subfield></datafield><datafield tag="938" ind1=" " ind2=" "><subfield code="a">ProQuest MyiLibrary Digital eBook Collection</subfield><subfield code="b">IDEB</subfield><subfield code="n">343355</subfield></datafield><datafield tag="938" ind1=" " ind2=" "><subfield code="a">YBP Library Services</subfield><subfield code="b">YANK</subfield><subfield code="n">3754963</subfield></datafield><datafield tag="938" ind1=" " ind2=" "><subfield code="a">Internet Archive</subfield><subfield code="b">INAR</subfield><subfield code="n">isbn_9789814329453</subfield></datafield><datafield tag="994" ind1=" " ind2=" "><subfield code="a">92</subfield><subfield code="b">GEBAY</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-4-EBA</subfield></datafield></record></collection> |
| id | ZDB-4-EBA-ocn775361436 |
| illustrated | Illustrated |
| indexdate | 2024-10-25T16:18:30Z |
| institution | BVB |
| isbn | 9789814329460 9814329460 1283433559 9781283433556 |
| language | English |
| oclc_num | 775361436 |
| open_access_boolean | |
| owner | MAIN |
| owner_facet | MAIN |
| physical | 1 online resource (xxv, 671 pages :) |
| psigel | ZDB-4-EBA |
| publishDate | 2011 |
| publishDateSearch | 2011 |
| publishDateSort | 2011 |
| publisher | World Scientific Publishing, |
| record_format | marc |
| spelling | Tindall, Donald. Recent advances in prostate cancer : basic science discoveries and clinical advances / Donald J. Tindall and Peter T. Scardino. Singapore : World Scientific Publishing, 2011. 1 online resource (xxv, 671 pages :) text txt rdacontent computer c rdamedia online resource cr rdacarrier Includes bibliographical references and index. Print version record. Contributors; Preface; Chapter 1 Pathology of Prostate Lawrence True and Funda Vakar-Lopez; Introduction; Prostate Anatomy; Prostate "Capsule"; Zones of the Prostate; Cell Types of the Prostate; Benign Prostatic Hypertrophy (BPH); Inflammation; Granulomatous Prostatitis; Chronic Prostatitis; Pre-Neoplastic Lesions; Prostatic Intraepithelial Neoplasia (PIN); Other Candidate Pre-Neoplastic Lesions; Prostate Carcinoma; Diagnosis of Prostate Cancer; Differential Diagnostic Considerations; Grading Prostate Carcinoma; Tertiary Gleason pattern; Percentage of Gleason patterns. Grade progressionSpindle Cell Lesions; Non-Prostate Spindle Cell Lesions; Prostate Spindle Cell Lesions; Sarcoma of Prostate; Carcinosarcoma (Sarcomatoid Carcinoma) of Prostate; Pathology of Non-Surgical Therapy; Radiation Therapy; Androgen Deprivation (Blockade) Therapy; Neoadjuvant Therapy; Recommendations for Pathology Reports; Needle Biopsy Reports; Radical Prostatectomy Reports; Surgical margin; Extraprostatic extension; Lymph node dissection; Tissue Biomarkers; Future Trends; References; Chapter 2 Genetic Basis for Prostate Cancer Stacy Loeb and William B. Isaacs; Introduction. Family-Based StudiesGenome-Wide Association Studies; Future Directions; Conclusions; References; Chapter 3 Androgen Receptor Converts from a Growth Suppressor in the Normal Prostate to an Oncogene in Prostate Cancer Donald J. Vander Griend and John T. Isaacs; Introduction; Androgen Receptor Suppresses the Growth of Normal Prostate Epithelial Cells; Androgen Receptor Functions as an Oncogene in Prostate Cancer; Clinical Implications of AR Conversion from a Growth Suppressor to an Oncogene; Loss of AR-Mediated Growth Suppression Without Gaining Oncogenic Ability; Acknowledgments; References. Chapter 4 Etiology: Role of ETS Factor Gene Fusions Jianghua Wang and Michael IttmannIntroduction; ETS Transcription Factor Gene Fusions in Prostate Cancer; Structure and Transcription of the TMPRSS2/ERG Fusion Gene; Origin of the TMPRSS2/ERG Fusion Gene; Alternative Splicing of the TMPRSS2/ERG Fusion Transcript; Pathological Correlations; The ETS Transcription Factor Gene Family; Biological Activities of the ERG and T/E Fusion Gene Protein; Association of T/E Fusion Gene Expression with Global Gene Expression and Copy Number Alterations in Prostate Cancer. Genetics of TMPRSS2/ERG Prostate CancerClinical Implications of the TMPRSS2/ERG Fusion Gene; Summary; References; Chapter 5 Etiology of Prostate Cancer: Role of Inflammation William G. Nelson, Angelo M. DeMarzo and Srinivasan Yegnasubramanian; Introduction; Inflammation in the Human Prostate and Prostate Cancer; Sex Steroid Hormones and Inflammation in the Prostate; Infections and Inflammation in the Prostate; Inflammation and Inherited Susceptibility to Prostate Cancer; The Diet and Inflammation in the Prostate; Inflammation and the Molecular Pathogenesis of Prostate Cancer. This book effectively summarizes our knowledge of recent advances in prostate cancer. It focuses on our state-of-the-art understanding of risk factors, prevention, detection, prognosis and treatment of prostate cancer and identifies basic science findings that are being translated into clinical practice. In addition, the book singles out key areas of research that have potential for clinical translation. Both basic scientists and clinicians will be invited to provide up-to-date reviews in each area of prostate cancer. During the last decade the pace of clinical discovery and the scientific advances in prostate cancer have been very rapid. For instance, currently there are more than 100 drugs in the pharmaceutical pipeline that have the potential for clinical management of prostate cancer. Therefore, it has been very difficult for clinicians and basic scientists to keep pace with the field as a whole. Recently, some of these discoveries are already having an impact on clinical practice. For example, the discovery of the androgen receptor gene amplification in prostate cancer has led to the development of a "super-antiandrogen", which is being tested in clinical trials. Also, recent knowledge of androgen synthesis in prostate cancer cells has led to clinical trials with steroid-metabolism inhibitors. Finally, robotic surgery has also dramatically changed clinical practice. Thus, this important book serves to provide readers with a one-stop overview of the field of prostate cancer research and its translation into the clinical arena Prostate Cancer. http://id.loc.gov/authorities/subjects/sh85107606 Prostate Cancer Diagnosis. Prostate Cancer Treatment. Prostatic Neoplasms diagnosis https://id.nlm.nih.gov/mesh/D011471Q000175 Prostatic Neoplasms therapy https://id.nlm.nih.gov/mesh/D011471Q000628 Prostatic Neoplasms https://id.nlm.nih.gov/mesh/D011471 Prostate Cancer. Prostate Cancer Traitement. HEALTH & FITNESS Diseases Cancer. bisacsh MEDICAL Oncology. bisacsh Prostate Cancer fast Prostate Cancer Diagnosis fast Prostate Cancer Treatment fast Scardino, Peter T. has work: Recent advances in prostate cancer (Text) https://id.oclc.org/worldcat/entity/E39PCGMjft3JJdWT6kXx6gGJXd https://id.oclc.org/worldcat/ontology/hasWork Print version: Tindall, Donald. Recent advances in prostate cancer. Singapore : World Scientific Publishing, 2011 9789814329453 (DLC) 2011499696 (OCoLC)755875175 FWS01 ZDB-4-EBA FWS_PDA_EBA https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=426401 Volltext CBO01 ZDB-4-EBA FWS_PDA_EBA https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=426401 Volltext |
| spellingShingle | Tindall, Donald Recent advances in prostate cancer : basic science discoveries and clinical advances / Contributors; Preface; Chapter 1 Pathology of Prostate Lawrence True and Funda Vakar-Lopez; Introduction; Prostate Anatomy; Prostate "Capsule"; Zones of the Prostate; Cell Types of the Prostate; Benign Prostatic Hypertrophy (BPH); Inflammation; Granulomatous Prostatitis; Chronic Prostatitis; Pre-Neoplastic Lesions; Prostatic Intraepithelial Neoplasia (PIN); Other Candidate Pre-Neoplastic Lesions; Prostate Carcinoma; Diagnosis of Prostate Cancer; Differential Diagnostic Considerations; Grading Prostate Carcinoma; Tertiary Gleason pattern; Percentage of Gleason patterns. Grade progressionSpindle Cell Lesions; Non-Prostate Spindle Cell Lesions; Prostate Spindle Cell Lesions; Sarcoma of Prostate; Carcinosarcoma (Sarcomatoid Carcinoma) of Prostate; Pathology of Non-Surgical Therapy; Radiation Therapy; Androgen Deprivation (Blockade) Therapy; Neoadjuvant Therapy; Recommendations for Pathology Reports; Needle Biopsy Reports; Radical Prostatectomy Reports; Surgical margin; Extraprostatic extension; Lymph node dissection; Tissue Biomarkers; Future Trends; References; Chapter 2 Genetic Basis for Prostate Cancer Stacy Loeb and William B. Isaacs; Introduction. Family-Based StudiesGenome-Wide Association Studies; Future Directions; Conclusions; References; Chapter 3 Androgen Receptor Converts from a Growth Suppressor in the Normal Prostate to an Oncogene in Prostate Cancer Donald J. Vander Griend and John T. Isaacs; Introduction; Androgen Receptor Suppresses the Growth of Normal Prostate Epithelial Cells; Androgen Receptor Functions as an Oncogene in Prostate Cancer; Clinical Implications of AR Conversion from a Growth Suppressor to an Oncogene; Loss of AR-Mediated Growth Suppression Without Gaining Oncogenic Ability; Acknowledgments; References. Chapter 4 Etiology: Role of ETS Factor Gene Fusions Jianghua Wang and Michael IttmannIntroduction; ETS Transcription Factor Gene Fusions in Prostate Cancer; Structure and Transcription of the TMPRSS2/ERG Fusion Gene; Origin of the TMPRSS2/ERG Fusion Gene; Alternative Splicing of the TMPRSS2/ERG Fusion Transcript; Pathological Correlations; The ETS Transcription Factor Gene Family; Biological Activities of the ERG and T/E Fusion Gene Protein; Association of T/E Fusion Gene Expression with Global Gene Expression and Copy Number Alterations in Prostate Cancer. Genetics of TMPRSS2/ERG Prostate CancerClinical Implications of the TMPRSS2/ERG Fusion Gene; Summary; References; Chapter 5 Etiology of Prostate Cancer: Role of Inflammation William G. Nelson, Angelo M. DeMarzo and Srinivasan Yegnasubramanian; Introduction; Inflammation in the Human Prostate and Prostate Cancer; Sex Steroid Hormones and Inflammation in the Prostate; Infections and Inflammation in the Prostate; Inflammation and Inherited Susceptibility to Prostate Cancer; The Diet and Inflammation in the Prostate; Inflammation and the Molecular Pathogenesis of Prostate Cancer. Prostate Cancer. http://id.loc.gov/authorities/subjects/sh85107606 Prostate Cancer Diagnosis. Prostate Cancer Treatment. Prostatic Neoplasms diagnosis https://id.nlm.nih.gov/mesh/D011471Q000175 Prostatic Neoplasms therapy https://id.nlm.nih.gov/mesh/D011471Q000628 Prostatic Neoplasms https://id.nlm.nih.gov/mesh/D011471 Prostate Cancer. Prostate Cancer Traitement. HEALTH & FITNESS Diseases Cancer. bisacsh MEDICAL Oncology. bisacsh Prostate Cancer fast Prostate Cancer Diagnosis fast Prostate Cancer Treatment fast |
| subject_GND | http://id.loc.gov/authorities/subjects/sh85107606 https://id.nlm.nih.gov/mesh/D011471Q000175 https://id.nlm.nih.gov/mesh/D011471Q000628 https://id.nlm.nih.gov/mesh/D011471 |
| title | Recent advances in prostate cancer : basic science discoveries and clinical advances / |
| title_auth | Recent advances in prostate cancer : basic science discoveries and clinical advances / |
| title_exact_search | Recent advances in prostate cancer : basic science discoveries and clinical advances / |
| title_full | Recent advances in prostate cancer : basic science discoveries and clinical advances / Donald J. Tindall and Peter T. Scardino. |
| title_fullStr | Recent advances in prostate cancer : basic science discoveries and clinical advances / Donald J. Tindall and Peter T. Scardino. |
| title_full_unstemmed | Recent advances in prostate cancer : basic science discoveries and clinical advances / Donald J. Tindall and Peter T. Scardino. |
| title_short | Recent advances in prostate cancer : |
| title_sort | recent advances in prostate cancer basic science discoveries and clinical advances |
| title_sub | basic science discoveries and clinical advances / |
| topic | Prostate Cancer. http://id.loc.gov/authorities/subjects/sh85107606 Prostate Cancer Diagnosis. Prostate Cancer Treatment. Prostatic Neoplasms diagnosis https://id.nlm.nih.gov/mesh/D011471Q000175 Prostatic Neoplasms therapy https://id.nlm.nih.gov/mesh/D011471Q000628 Prostatic Neoplasms https://id.nlm.nih.gov/mesh/D011471 Prostate Cancer. Prostate Cancer Traitement. HEALTH & FITNESS Diseases Cancer. bisacsh MEDICAL Oncology. bisacsh Prostate Cancer fast Prostate Cancer Diagnosis fast Prostate Cancer Treatment fast |
| topic_facet | Prostate Cancer. Prostate Cancer Diagnosis. Prostate Cancer Treatment. Prostatic Neoplasms diagnosis Prostatic Neoplasms therapy Prostatic Neoplasms Prostate Cancer Traitement. HEALTH & FITNESS Diseases Cancer. MEDICAL Oncology. Prostate Cancer Prostate Cancer Diagnosis Prostate Cancer Treatment |
| url | https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=426401 |
| work_keys_str_mv | AT tindalldonald recentadvancesinprostatecancerbasicsciencediscoveriesandclinicaladvances AT scardinopetert recentadvancesinprostatecancerbasicsciencediscoveriesandclinicaladvances |