The dynamic neuron :: a comprehensive survey of the neurochemical basis of synaptic plasticity /
The traditional model of synapses as fixed structures has been replaced by a dynamic one in which synapses are constantly being deleted and replaced. This book, written by a leading researcher on the neurochemistry of schizophrenia, integrates material from neuroscience and cell biology to provide a...
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Cambridge, Mass. :
MIT Press,
©2002.
©2002 |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Zusammenfassung: | The traditional model of synapses as fixed structures has been replaced by a dynamic one in which synapses are constantly being deleted and replaced. This book, written by a leading researcher on the neurochemistry of schizophrenia, integrates material from neuroscience and cell biology to provide a comprehensive account of our current knowledge of the neurochemical basis of synaptic plasticity. The book presents the evidence for synaptic plasticity, an account of the dendritic spine and the glutamate synapse with a focus on redox mechanisms, and the biochemical basis of the Hebbian synapse. It discusses the role of endocytosis, special proteins, and local protein synthesis. Additional topics include volume transmission, arachidonic acid signaling, hormonal modulation, and psychological stress. Finally, the book considers pharmacological and clinical implications of current research, particularly with reference to schizophrenia and Alzheimer's disease. |
| Beschreibung: | "A Bradford book." |
| Beschreibung: | 1 online resource (viii, 150 pages) : illustrations |
| Bibliographie: | Includes bibliographical references (pages 107-143) and index. |
| ISBN: | 9780262283984 0262283980 0585442592 9780585442594 0262264676 9780262264679 |
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| 245 | 1 | 4 | |a The dynamic neuron : |b a comprehensive survey of the neurochemical basis of synaptic plasticity / |c John Smythies. |
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| 505 | 0 | 0 | |g 1. |t Synaptic biochemistry -- |g 2. |t Endocytosis and exocytosis -- |g 3. |t Special proteins -- |g 4. |t Miscellaneous items -- |g 5. |t Pharmoacological implications and clinical applications -- |g 6. |t Conclusions. |
| 520 | 8 | |a The traditional model of synapses as fixed structures has been replaced by a dynamic one in which synapses are constantly being deleted and replaced. This book, written by a leading researcher on the neurochemistry of schizophrenia, integrates material from neuroscience and cell biology to provide a comprehensive account of our current knowledge of the neurochemical basis of synaptic plasticity. The book presents the evidence for synaptic plasticity, an account of the dendritic spine and the glutamate synapse with a focus on redox mechanisms, and the biochemical basis of the Hebbian synapse. It discusses the role of endocytosis, special proteins, and local protein synthesis. Additional topics include volume transmission, arachidonic acid signaling, hormonal modulation, and psychological stress. Finally, the book considers pharmacological and clinical implications of current research, particularly with reference to schizophrenia and Alzheimer's disease. | |
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| author | Smythies, John R. (John Raymond), 1922- |
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| author_facet | Smythies, John R. (John Raymond), 1922- |
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| contents | Synaptic biochemistry -- Endocytosis and exocytosis -- Special proteins -- Miscellaneous items -- Pharmoacological implications and clinical applications -- Conclusions. |
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| publisher | MIT Press, |
| record_format | marc |
| spelling | Smythies, John R. (John Raymond), 1922- http://id.loc.gov/authorities/names/n50014794 The dynamic neuron : a comprehensive survey of the neurochemical basis of synaptic plasticity / John Smythies. Cambridge, Mass. : MIT Press, ©2002. ©2002 1 online resource (viii, 150 pages) : illustrations text txt rdacontent computer c rdamedia online resource cr rdacarrier text file rdaft "A Bradford book." Includes bibliographical references (pages 107-143) and index. Print version record. 1. Synaptic biochemistry -- 2. Endocytosis and exocytosis -- 3. Special proteins -- 4. Miscellaneous items -- 5. Pharmoacological implications and clinical applications -- 6. Conclusions. The traditional model of synapses as fixed structures has been replaced by a dynamic one in which synapses are constantly being deleted and replaced. This book, written by a leading researcher on the neurochemistry of schizophrenia, integrates material from neuroscience and cell biology to provide a comprehensive account of our current knowledge of the neurochemical basis of synaptic plasticity. The book presents the evidence for synaptic plasticity, an account of the dendritic spine and the glutamate synapse with a focus on redox mechanisms, and the biochemical basis of the Hebbian synapse. It discusses the role of endocytosis, special proteins, and local protein synthesis. Additional topics include volume transmission, arachidonic acid signaling, hormonal modulation, and psychological stress. Finally, the book considers pharmacological and clinical implications of current research, particularly with reference to schizophrenia and Alzheimer's disease. English. Neuroplasticity. http://id.loc.gov/authorities/subjects/sh85091160 Neurochemistry. http://id.loc.gov/authorities/subjects/sh85091116 Neuronal Plasticity Neurochemistry https://id.nlm.nih.gov/mesh/D009448 Nerve Tissue chemistry Plasticité neuronale. Neurochimie. SOCIAL SCIENCE Anthropology Physical. bisacsh Neurochemistry fast Neuroplasticity fast Neuroplasticiteit. gtt Eiwitten. gtt Neuronen. (NL-LeOCL)078602890 gtt Stress. gtt Hormonen. (NL-LeOCL)078537576 gtt Print version: Smythies, John R. (John Raymond), 1922- Dynamic neuron. Cambridge, Mass. : MIT Press, ©2002 0262194732 (DLC) 2001058700 (OCoLC)48517367 FWS01 ZDB-4-EBA FWS_PDA_EBA https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=70955 Volltext |
| spellingShingle | Smythies, John R. (John Raymond), 1922- The dynamic neuron : a comprehensive survey of the neurochemical basis of synaptic plasticity / Synaptic biochemistry -- Endocytosis and exocytosis -- Special proteins -- Miscellaneous items -- Pharmoacological implications and clinical applications -- Conclusions. Neuroplasticity. http://id.loc.gov/authorities/subjects/sh85091160 Neurochemistry. http://id.loc.gov/authorities/subjects/sh85091116 Neuronal Plasticity Neurochemistry https://id.nlm.nih.gov/mesh/D009448 Nerve Tissue chemistry Plasticité neuronale. Neurochimie. SOCIAL SCIENCE Anthropology Physical. bisacsh Neurochemistry fast Neuroplasticity fast Neuroplasticiteit. gtt Eiwitten. gtt Neuronen. (NL-LeOCL)078602890 gtt Stress. gtt Hormonen. (NL-LeOCL)078537576 gtt |
| subject_GND | http://id.loc.gov/authorities/subjects/sh85091160 http://id.loc.gov/authorities/subjects/sh85091116 https://id.nlm.nih.gov/mesh/D009448 (NL-LeOCL)078602890 (NL-LeOCL)078537576 |
| title | The dynamic neuron : a comprehensive survey of the neurochemical basis of synaptic plasticity / |
| title_alt | Synaptic biochemistry -- Endocytosis and exocytosis -- Special proteins -- Miscellaneous items -- Pharmoacological implications and clinical applications -- Conclusions. |
| title_auth | The dynamic neuron : a comprehensive survey of the neurochemical basis of synaptic plasticity / |
| title_exact_search | The dynamic neuron : a comprehensive survey of the neurochemical basis of synaptic plasticity / |
| title_full | The dynamic neuron : a comprehensive survey of the neurochemical basis of synaptic plasticity / John Smythies. |
| title_fullStr | The dynamic neuron : a comprehensive survey of the neurochemical basis of synaptic plasticity / John Smythies. |
| title_full_unstemmed | The dynamic neuron : a comprehensive survey of the neurochemical basis of synaptic plasticity / John Smythies. |
| title_short | The dynamic neuron : |
| title_sort | dynamic neuron a comprehensive survey of the neurochemical basis of synaptic plasticity |
| title_sub | a comprehensive survey of the neurochemical basis of synaptic plasticity / |
| topic | Neuroplasticity. http://id.loc.gov/authorities/subjects/sh85091160 Neurochemistry. http://id.loc.gov/authorities/subjects/sh85091116 Neuronal Plasticity Neurochemistry https://id.nlm.nih.gov/mesh/D009448 Nerve Tissue chemistry Plasticité neuronale. Neurochimie. SOCIAL SCIENCE Anthropology Physical. bisacsh Neurochemistry fast Neuroplasticity fast Neuroplasticiteit. gtt Eiwitten. gtt Neuronen. (NL-LeOCL)078602890 gtt Stress. gtt Hormonen. (NL-LeOCL)078537576 gtt |
| topic_facet | Neuroplasticity. Neurochemistry. Neuronal Plasticity Neurochemistry Nerve Tissue chemistry Plasticité neuronale. Neurochimie. SOCIAL SCIENCE Anthropology Physical. Neuroplasticity Neuroplasticiteit. Eiwitten. Neuronen. Stress. Hormonen. |
| url | https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=70955 |
| work_keys_str_mv | AT smythiesjohnr thedynamicneuronacomprehensivesurveyoftheneurochemicalbasisofsynapticplasticity AT smythiesjohnr dynamicneuronacomprehensivesurveyoftheneurochemicalbasisofsynapticplasticity |