Adverse Outcome Pathway on Androgen receptor agonism leading to male-biased sex ratio:
This adverse outcome pathway links androgen receptor agonism in teleost fish during gonadogenesis to male-biased sexual differentiation and consequently, reduced population growth rate. Sex determination in teleost fishes is highly plastic; it can be genetically or environmentally influenced. Specie...
Gespeichert in:
1. Verfasser: | |
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Weitere Verfasser: | , , , |
Format: | Elektronisch E-Book |
Sprache: | English |
Veröffentlicht: |
Paris
OECD Publishing
2023
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Schriftenreihe: | OECD Series on Adverse Outcome Pathways
no.35 |
Schlagworte: | |
Online-Zugang: | Volltext |
Zusammenfassung: | This adverse outcome pathway links androgen receptor agonism in teleost fish during gonadogenesis to male-biased sexual differentiation and consequently, reduced population growth rate. Sex determination in teleost fishes is highly plastic; it can be genetically or environmentally influenced. Species with environmentally-based sex determination in particular can be very sensitive to exogenous chemicals during the period of differentiation. Exogenous hormones are of ecological concern because they have the potential to alter gonad development and sex differentiation. This AOP is referred to as AOP 376 in the Collaborative Adverse Outcome Pathway Wiki (AOP-Wiki). |
Beschreibung: | 1 Online-Ressource (57 p.) 21 x 28cm. |
DOI: | 10.1787/6f60dce3-en |
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author | Santana Rodriguez, Kelvin J.. |
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doi_str_mv | 10.1787/6f60dce3-en |
format | Electronic eBook |
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indexdate | 2024-11-26T14:55:33Z |
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language | English |
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physical | 1 Online-Ressource (57 p.) 21 x 28cm. |
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series2 | OECD Series on Adverse Outcome Pathways |
spelling | Santana Rodriguez, Kelvin J... VerfasserIn aut Adverse Outcome Pathway on Androgen receptor agonism leading to male-biased sex ratio Kelvin J., Santana Rodriguez ... [et al] Paris OECD Publishing 2023 1 Online-Ressource (57 p.) 21 x 28cm. Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier OECD Series on Adverse Outcome Pathways no.35 This adverse outcome pathway links androgen receptor agonism in teleost fish during gonadogenesis to male-biased sexual differentiation and consequently, reduced population growth rate. Sex determination in teleost fishes is highly plastic; it can be genetically or environmentally influenced. Species with environmentally-based sex determination in particular can be very sensitive to exogenous chemicals during the period of differentiation. Exogenous hormones are of ecological concern because they have the potential to alter gonad development and sex differentiation. This AOP is referred to as AOP 376 in the Collaborative Adverse Outcome Pathway Wiki (AOP-Wiki). Environment Villeneuve, Daniel L... MitwirkendeR ctb Jensen, Kathleen M... MitwirkendeR ctb Ankley, Gerald T... MitwirkendeR ctb Miller, David H... MitwirkendeR ctb FWS01 ZDB-13-SOC FWS_PDA_SOC https://doi.org/10.1787/6f60dce3-en Volltext |
spellingShingle | Santana Rodriguez, Kelvin J.. Adverse Outcome Pathway on Androgen receptor agonism leading to male-biased sex ratio Environment |
title | Adverse Outcome Pathway on Androgen receptor agonism leading to male-biased sex ratio |
title_auth | Adverse Outcome Pathway on Androgen receptor agonism leading to male-biased sex ratio |
title_exact_search | Adverse Outcome Pathway on Androgen receptor agonism leading to male-biased sex ratio |
title_full | Adverse Outcome Pathway on Androgen receptor agonism leading to male-biased sex ratio Kelvin J., Santana Rodriguez ... [et al] |
title_fullStr | Adverse Outcome Pathway on Androgen receptor agonism leading to male-biased sex ratio Kelvin J., Santana Rodriguez ... [et al] |
title_full_unstemmed | Adverse Outcome Pathway on Androgen receptor agonism leading to male-biased sex ratio Kelvin J., Santana Rodriguez ... [et al] |
title_short | Adverse Outcome Pathway on Androgen receptor agonism leading to male-biased sex ratio |
title_sort | adverse outcome pathway on androgen receptor agonism leading to male biased sex ratio |
topic | Environment |
topic_facet | Environment |
url | https://doi.org/10.1787/6f60dce3-en |
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