Targeting oncogenic driver mutations in lung cancer:
The recent advances in the field of molecular diagnostic techniques have led to the identification of targetable alterations prompting a paradigm shift in the management of non-small cell lung cancer (NSCLC) and an era of precision oncology. This Element highlights the most clinically relevant oncog...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Book |
| Language: | English |
| Published: |
Cambridge, United Kingdom ; New York, NY, USA
Cambridge University Press
2023
|
| Series: | Cambridge elements: elements in molecular oncology
|
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Summary: | The recent advances in the field of molecular diagnostic techniques have led to the identification of targetable alterations prompting a paradigm shift in the management of non-small cell lung cancer (NSCLC) and an era of precision oncology. This Element highlights the most clinically relevant oncogenic drivers other than EGFR, their management and current advancements in treatment. It also examines the different challenges in resistance to targeted therapies and diagnostic dilemmas for each oncogenic driver and the future direction of NSCLC management |
| Physical Description: | 87 Seiten Illustrationen 152 x 227 mm |
| ISBN: | 9781009336130 1009336134 |
Staff View
MARC
| LEADER | 00000nam a2200000 c 4500 | ||
|---|---|---|---|
| 001 | BV049346260 | ||
| 003 | DE-604 | ||
| 005 | 20240212 | ||
| 007 | t | ||
| 008 | 230929s2023 a||| |||| 00||| eng d | ||
| 020 | |a 9781009336130 |c Broschur : EUR 20.95 |9 978-1-009-33613-0 | ||
| 020 | |a 1009336134 |9 1-009-33613-4 | ||
| 024 | 3 | |a 9781009336130 | |
| 035 | |a (OCoLC)1398600963 | ||
| 035 | |a (DE-599)BVBBV049346260 | ||
| 040 | |a DE-604 |b ger |e rda | ||
| 041 | 0 | |a eng | |
| 049 | |a DE-355 | ||
| 084 | |a XH 5765 |0 (DE-625)152918:13144 |2 rvk | ||
| 100 | 1 | |a Lee, Matthew |d 1980- |e Verfasser |0 (DE-588)1281543489 |4 aut | |
| 245 | 1 | 0 | |a Targeting oncogenic driver mutations in lung cancer |c Matthew Lee, Fawzi Abu Rous, Alain Borczuk, Stephen Liu, Shirish Gadgeel |
| 264 | 1 | |a Cambridge, United Kingdom ; New York, NY, USA |b Cambridge University Press |c 2023 | |
| 300 | |a 87 Seiten |b Illustrationen |c 152 x 227 mm | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 490 | 0 | |a Cambridge elements: elements in molecular oncology | |
| 520 | |a The recent advances in the field of molecular diagnostic techniques have led to the identification of targetable alterations prompting a paradigm shift in the management of non-small cell lung cancer (NSCLC) and an era of precision oncology. This Element highlights the most clinically relevant oncogenic drivers other than EGFR, their management and current advancements in treatment. It also examines the different challenges in resistance to targeted therapies and diagnostic dilemmas for each oncogenic driver and the future direction of NSCLC management | ||
| 650 | 4 | |a Medical diagnosis / BIC2 | |
| 650 | 4 | |a Oncology / BIC2 | |
| 650 | 4 | |a Respiratory medicine / BIC2 | |
| 700 | 1 | |a Abu Rous, Fawzi |e Verfasser |4 aut | |
| 700 | 1 | |a Borczuk, Alain C. |e Verfasser |0 (DE-588)1280937947 |4 aut | |
| 700 | 1 | |a Liu, Stephen |e Verfasser |4 aut | |
| 700 | 1 | |a Gadgeel, Shirish |e Verfasser |0 (DE-588)1232920436 |4 aut | |
| 856 | 4 | 2 | |m Digitalisierung UB Regensburg - ADAM Catalogue Enrichment |q application/pdf |u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=034606729&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |3 Inhaltsverzeichnis |
| 999 | |a oai:aleph.bib-bvb.de:BVB01-034606729 | ||
Record in the Search Index
| _version_ | 1804185875730399232 |
|---|---|
| adam_text | Contents 1 Introduction 1 2 ALK Gene Rearrangements 5 3 ROS 7 Gene Rearrangements 12 4 RET Gene Rearrangements 16 5 MET Alterations 21 6 KRAS Point Mutations 27 7 В-RAF Point Mutations 32 8 NTRK1/2/3 Gene Fusions 39 9 ERBB2 (HER2) Mutations 43 10 Diagnostic Strategies References 48 54
|
| adam_txt |
Contents 1 Introduction 1 2 ALK Gene Rearrangements 5 3 ROS 7 Gene Rearrangements 12 4 RET Gene Rearrangements 16 5 MET Alterations 21 6 KRAS Point Mutations 27 7 В-RAF Point Mutations 32 8 NTRK1/2/3 Gene Fusions 39 9 ERBB2 (HER2) Mutations 43 10 Diagnostic Strategies References 48 54 |
| any_adam_object | 1 |
| any_adam_object_boolean | 1 |
| author | Lee, Matthew 1980- Abu Rous, Fawzi Borczuk, Alain C. Liu, Stephen Gadgeel, Shirish |
| author_GND | (DE-588)1281543489 (DE-588)1280937947 (DE-588)1232920436 |
| author_facet | Lee, Matthew 1980- Abu Rous, Fawzi Borczuk, Alain C. Liu, Stephen Gadgeel, Shirish |
| author_role | aut aut aut aut aut |
| author_sort | Lee, Matthew 1980- |
| author_variant | m l ml r f a rf rfa a c b ac acb s l sl s g sg |
| building | Verbundindex |
| bvnumber | BV049346260 |
| classification_rvk | XH 5765 |
| ctrlnum | (OCoLC)1398600963 (DE-599)BVBBV049346260 |
| discipline | Medizin |
| discipline_str_mv | Medizin |
| format | Book |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>02293nam a2200409 c 4500</leader><controlfield tag="001">BV049346260</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">20240212 </controlfield><controlfield tag="007">t</controlfield><controlfield tag="008">230929s2023 a||| |||| 00||| eng d</controlfield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9781009336130</subfield><subfield code="c">Broschur : EUR 20.95</subfield><subfield code="9">978-1-009-33613-0</subfield></datafield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">1009336134</subfield><subfield code="9">1-009-33613-4</subfield></datafield><datafield tag="024" ind1="3" ind2=" "><subfield code="a">9781009336130</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)1398600963</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV049346260</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">rda</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-355</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">XH 5765</subfield><subfield code="0">(DE-625)152918:13144</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Lee, Matthew</subfield><subfield code="d">1980-</subfield><subfield code="e">Verfasser</subfield><subfield code="0">(DE-588)1281543489</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Targeting oncogenic driver mutations in lung cancer</subfield><subfield code="c">Matthew Lee, Fawzi Abu Rous, Alain Borczuk, Stephen Liu, Shirish Gadgeel</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Cambridge, United Kingdom ; New York, NY, USA</subfield><subfield code="b">Cambridge University Press</subfield><subfield code="c">2023</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">87 Seiten</subfield><subfield code="b">Illustrationen</subfield><subfield code="c">152 x 227 mm</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">n</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">nc</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="490" ind1="0" ind2=" "><subfield code="a">Cambridge elements: elements in molecular oncology</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">The recent advances in the field of molecular diagnostic techniques have led to the identification of targetable alterations prompting a paradigm shift in the management of non-small cell lung cancer (NSCLC) and an era of precision oncology. This Element highlights the most clinically relevant oncogenic drivers other than EGFR, their management and current advancements in treatment. It also examines the different challenges in resistance to targeted therapies and diagnostic dilemmas for each oncogenic driver and the future direction of NSCLC management</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Medical diagnosis / BIC2</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Oncology / BIC2</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Respiratory medicine / BIC2</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Abu Rous, Fawzi</subfield><subfield code="e">Verfasser</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Borczuk, Alain C.</subfield><subfield code="e">Verfasser</subfield><subfield code="0">(DE-588)1280937947</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Liu, Stephen</subfield><subfield code="e">Verfasser</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Gadgeel, Shirish</subfield><subfield code="e">Verfasser</subfield><subfield code="0">(DE-588)1232920436</subfield><subfield code="4">aut</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="m">Digitalisierung UB Regensburg - ADAM Catalogue Enrichment</subfield><subfield code="q">application/pdf</subfield><subfield code="u">http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=034606729&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA</subfield><subfield code="3">Inhaltsverzeichnis</subfield></datafield><datafield tag="999" ind1=" " ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-034606729</subfield></datafield></record></collection> |
| id | DE-604.BV049346260 |
| illustrated | Illustrated |
| index_date | 2024-07-03T22:48:24Z |
| indexdate | 2024-07-10T10:02:11Z |
| institution | BVB |
| isbn | 9781009336130 1009336134 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-034606729 |
| oclc_num | 1398600963 |
| open_access_boolean | |
| owner | DE-355 DE-BY-UBR |
| owner_facet | DE-355 DE-BY-UBR |
| physical | 87 Seiten Illustrationen 152 x 227 mm |
| publishDate | 2023 |
| publishDateSearch | 2023 |
| publishDateSort | 2023 |
| publisher | Cambridge University Press |
| record_format | marc |
| series2 | Cambridge elements: elements in molecular oncology |
| spelling | Lee, Matthew 1980- Verfasser (DE-588)1281543489 aut Targeting oncogenic driver mutations in lung cancer Matthew Lee, Fawzi Abu Rous, Alain Borczuk, Stephen Liu, Shirish Gadgeel Cambridge, United Kingdom ; New York, NY, USA Cambridge University Press 2023 87 Seiten Illustrationen 152 x 227 mm txt rdacontent n rdamedia nc rdacarrier Cambridge elements: elements in molecular oncology The recent advances in the field of molecular diagnostic techniques have led to the identification of targetable alterations prompting a paradigm shift in the management of non-small cell lung cancer (NSCLC) and an era of precision oncology. This Element highlights the most clinically relevant oncogenic drivers other than EGFR, their management and current advancements in treatment. It also examines the different challenges in resistance to targeted therapies and diagnostic dilemmas for each oncogenic driver and the future direction of NSCLC management Medical diagnosis / BIC2 Oncology / BIC2 Respiratory medicine / BIC2 Abu Rous, Fawzi Verfasser aut Borczuk, Alain C. Verfasser (DE-588)1280937947 aut Liu, Stephen Verfasser aut Gadgeel, Shirish Verfasser (DE-588)1232920436 aut Digitalisierung UB Regensburg - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=034606729&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Lee, Matthew 1980- Abu Rous, Fawzi Borczuk, Alain C. Liu, Stephen Gadgeel, Shirish Targeting oncogenic driver mutations in lung cancer Medical diagnosis / BIC2 Oncology / BIC2 Respiratory medicine / BIC2 |
| title | Targeting oncogenic driver mutations in lung cancer |
| title_auth | Targeting oncogenic driver mutations in lung cancer |
| title_exact_search | Targeting oncogenic driver mutations in lung cancer |
| title_exact_search_txtP | Targeting oncogenic driver mutations in lung cancer |
| title_full | Targeting oncogenic driver mutations in lung cancer Matthew Lee, Fawzi Abu Rous, Alain Borczuk, Stephen Liu, Shirish Gadgeel |
| title_fullStr | Targeting oncogenic driver mutations in lung cancer Matthew Lee, Fawzi Abu Rous, Alain Borczuk, Stephen Liu, Shirish Gadgeel |
| title_full_unstemmed | Targeting oncogenic driver mutations in lung cancer Matthew Lee, Fawzi Abu Rous, Alain Borczuk, Stephen Liu, Shirish Gadgeel |
| title_short | Targeting oncogenic driver mutations in lung cancer |
| title_sort | targeting oncogenic driver mutations in lung cancer |
| topic | Medical diagnosis / BIC2 Oncology / BIC2 Respiratory medicine / BIC2 |
| topic_facet | Medical diagnosis / BIC2 Oncology / BIC2 Respiratory medicine / BIC2 |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=034606729&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT leematthew targetingoncogenicdrivermutationsinlungcancer AT aburousfawzi targetingoncogenicdrivermutationsinlungcancer AT borczukalainc targetingoncogenicdrivermutationsinlungcancer AT liustephen targetingoncogenicdrivermutationsinlungcancer AT gadgeelshirish targetingoncogenicdrivermutationsinlungcancer |