Personalized drug screening for functional tumor profiling:
Despite considerable advances in our understanding of the biology that underlies tumor development and progression of cancer and the rapidly evolving field of personalized medicine, cancer is still one of the deadliest diseases. Many cancer patients have benefited from the survival improvements obse...
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| Main Authors: | , , , |
|---|---|
| Format: | Book |
| Language: | English |
| Published: |
Cambridge, United Kingdom ; New York, NY, USA
Cambridge University Press
2022
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| Series: | Cambridge elements: elements in molecular oncology
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| Subjects: | |
| Online Access: | Cover original |
| Summary: | Despite considerable advances in our understanding of the biology that underlies tumor development and progression of cancer and the rapidly evolving field of personalized medicine, cancer is still one of the deadliest diseases. Many cancer patients have benefited from the survival improvements observed with targeted therapies but only a small subset of patients receiving targeted drugs experience an objective response. Because cancer is a complex and heterogeneous disease, the search for effective cancer treatments will need to address not only patient-specific molecular defects but also aspects of the tumor microenvironment. The functional tumor profiling directly measures the cellular phenotype, in particular tumor growth, in response to drugs using patient-derived tumor models and might be the next step toward precision oncology. In this Element, the authors discuss the personalized drug screening as a novel patient stratification strategy for the determination of individualized treatment choices in oncology |
| Physical Description: | 22 Seiten Illustration 151 x 228 mm |
| ISBN: | 9781009016933 1009016938 |
Staff View
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| author | El-Khoury, Victoria 1977- Michel, Tatiana 1975- Kim, Hichul 1976- Kwon, Yong-Jun 1976- |
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| id | DE-604.BV049346255 |
| illustrated | Illustrated |
| index_date | 2024-07-03T22:48:24Z |
| indexdate | 2024-07-10T10:02:11Z |
| institution | BVB |
| isbn | 9781009016933 1009016938 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-034606724 |
| oclc_num | 1422497242 |
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| physical | 22 Seiten Illustration 151 x 228 mm |
| publishDate | 2022 |
| publishDateSearch | 2022 |
| publishDateSort | 2022 |
| publisher | Cambridge University Press |
| record_format | marc |
| series2 | Cambridge elements: elements in molecular oncology |
| spelling | El-Khoury, Victoria 1977- Verfasser (DE-588)1264159633 aut Personalized drug screening for functional tumor profiling Victoria El-Khoury (Luxembourg Institute of Health), Tatiana Michel (Luxembourg Institute of Health), Hichul Kim (Luxembourg Institute of Health), Yong-Jun Kwon (Luxembourg Institute of Health) Cambridge, United Kingdom ; New York, NY, USA Cambridge University Press 2022 22 Seiten Illustration 151 x 228 mm txt rdacontent n rdamedia nc rdacarrier Cambridge elements: elements in molecular oncology Despite considerable advances in our understanding of the biology that underlies tumor development and progression of cancer and the rapidly evolving field of personalized medicine, cancer is still one of the deadliest diseases. Many cancer patients have benefited from the survival improvements observed with targeted therapies but only a small subset of patients receiving targeted drugs experience an objective response. Because cancer is a complex and heterogeneous disease, the search for effective cancer treatments will need to address not only patient-specific molecular defects but also aspects of the tumor microenvironment. The functional tumor profiling directly measures the cellular phenotype, in particular tumor growth, in response to drugs using patient-derived tumor models and might be the next step toward precision oncology. In this Element, the authors discuss the personalized drug screening as a novel patient stratification strategy for the determination of individualized treatment choices in oncology Medicine: general issues / BIC2 Oncology / BIC2 Michel, Tatiana 1975- Verfasser (DE-588)1264160062 aut Kim, Hichul 1976- Verfasser (DE-588)1264160437 aut Kwon, Yong-Jun 1976- Verfasser (DE-588)1264160739 aut https://www.lehmanns.de/media/104110993 Cover original |
| spellingShingle | El-Khoury, Victoria 1977- Michel, Tatiana 1975- Kim, Hichul 1976- Kwon, Yong-Jun 1976- Personalized drug screening for functional tumor profiling Medicine: general issues / BIC2 Oncology / BIC2 |
| title | Personalized drug screening for functional tumor profiling |
| title_auth | Personalized drug screening for functional tumor profiling |
| title_exact_search | Personalized drug screening for functional tumor profiling |
| title_exact_search_txtP | Personalized drug screening for functional tumor profiling |
| title_full | Personalized drug screening for functional tumor profiling Victoria El-Khoury (Luxembourg Institute of Health), Tatiana Michel (Luxembourg Institute of Health), Hichul Kim (Luxembourg Institute of Health), Yong-Jun Kwon (Luxembourg Institute of Health) |
| title_fullStr | Personalized drug screening for functional tumor profiling Victoria El-Khoury (Luxembourg Institute of Health), Tatiana Michel (Luxembourg Institute of Health), Hichul Kim (Luxembourg Institute of Health), Yong-Jun Kwon (Luxembourg Institute of Health) |
| title_full_unstemmed | Personalized drug screening for functional tumor profiling Victoria El-Khoury (Luxembourg Institute of Health), Tatiana Michel (Luxembourg Institute of Health), Hichul Kim (Luxembourg Institute of Health), Yong-Jun Kwon (Luxembourg Institute of Health) |
| title_short | Personalized drug screening for functional tumor profiling |
| title_sort | personalized drug screening for functional tumor profiling |
| topic | Medicine: general issues / BIC2 Oncology / BIC2 |
| topic_facet | Medicine: general issues / BIC2 Oncology / BIC2 |
| url | https://www.lehmanns.de/media/104110993 |
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