Microbiome in neurological disease:
Saved in:
| Other Authors: | |
|---|---|
| Format: | Book |
| Language: | English |
| Published: |
Cambridge, MA ; San Diego, CA
Academic Press, an imprint of Elsevier
2022
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| Edition: | First edition |
| Series: | International review of neurobiology
volume 167 |
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Physical Description: | xvi, 290 Seiten Illustrationen |
| ISBN: | 9780323991766 |
Staff View
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Record in the Search Index
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| adam_text | Contents Contributors ix Introduction: Unraveling the complex contributions of indigenous microbes to neurological health and disease xi 1. Intersections of the microbiome and early neurodevelopment 1 Helen E. Vuong 1. Microbiota regulation of brain and behavior 2 2. Prenatal and early postnatal microbiota 3 3. Impact of microbiota on neurodevelopment: Considerations of the developmental origins of health and disease 7 4. Potential mechanisms of microbiota influences on neurodevelopment 14 5. Future directions 17 References 18 2. Microbiome influences on neuro-immune interactions in neurodegenerative disease 25 Kelly B. Menees, Brittney A. Otero, and Malú Gámez Tansey 1. Introduction 26 2. Microbiome influences on microglia 27 3. Microbiome influences on astrocytes 28 4. Microbiome influences on other immune cells 30 5. Gut microbiome studies in human populations 31 6. Gut microbiome studies in model organisms of aging or neurological disease 7. Blood brain barrier (BBB) 35 36 8. Vagus nerve 37 9. Mediators of gut/brain crosstalk 38 10. Therapeutic potential of probiotics and prebiotics to treat neurodegenerative disease 45 11. Future challenges/directions 46 Acknowledgments 47 Conflict of interests 47 References 47 V
Contents vi 3. The many genomes of Parkinson s disease 59 Haydeh Payami 1. Holistic view 60 2. Hologenome 61 3. PD and the microbiome 69 4. Concluding remarks 75 Funding sources 75 References 76 4. Intestinal microbiota and neuroinflammation in Parkinson s disease: At the helm of the gut-brain axis 81 Richard A. Manfready, Christopher G. Goetz, and Ali Keshavarzian 1. Introduction: Intestinal microbiota in health anddisease 82 2. Microbial signatures and their significance in Parkinson s disease 84 3. Neuroprotection by short-chain fatty acids 87 4. Microbial effects on neuroinflammation 88 5. Environmental and dietary influences 89 6. Common medications and microbiota 90 7. Therapeutic strategies 91 8. Conclusions 93 References 94 5. The emerging role of the microbiome in Alzheimer s disease 101 Caroline Wasén, Ella Simonsen, Millicent N. Ekwudo, Martin R. Profant, and Laura Μ. Cox 1. Alzheimer s disease ’02 2. The gut microbiota influence health and disease in aging 103 3. The gut microbiota of patients with Alzheimer s disease 104 4. Antibiotics and Alzheimer s disease 05 5. The gut microbiota of murine models of Alzheimer s disease 107 6. The gut microbiota and the immune system in Alzheimer s disease 13 7. Interactions between the diet, the microbiota, and Alzheimer s disease 11 7 8. Prebiotics ’ 20 9. Microbial mediators associated with Alzheimer s disease ’21 10. Potential use of probiotics for the treatment of AD 123 References 131
Contents vii 6, The microbiota-gut-brain axis in Huntington s disease 141 Chloe J. Love, Bethany A. Masson, Carolina Gubert, and Anthony J. Hannan 1. Microbiota-gut-brain axis 142 2. Gut microbiota disruption 149 3. Huntington s disease 152 4. The gut microbiota in HD 157 5. Gut microbiota and HD motor symptoms 158 6. Gut microbiota and HD-induced weightloss 159 7. Gut microbiota and cognition in HD 161 8. Gut microbiota and immune function inHD 162 9. Microbiota-gut-brain axis in HD 163 10. Gut microbiota and HD sexual dimorphism 165 11. Environment 166 12. Limitations 170 13. Conclusion 170 171 References 7. Role of the gut microbiome in multiple sclerosis: From etiology to therapeutics 185 Shailesh K. Shahi, Meeta Yadav, Sudeep Ghimire, and Ashutosh K. Mangalam 1. Microbiome associations studies in MS 187 2. Mechanisms of gut dysbiosis 193 3. Influence of diet on the pathobiology of MS 199 4. Targeting gut bacteria to treat multiple sclerosis 199 5. Conclusions 207 Acknowledgments 208 Conflict of interest statement 208 References 208 8. Interactions between the gut microbiome and ketogenic diet in refractory epilepsy 217 Ezgi Özcan, Gregory R. Lum, and Elaine Y. Hsiao 1. Introduction to epilepsy 2. Increasing interest in the microbiome and epilepsy 218 219 3. Ketogenic diet andepilepsy 224 4. Ketogenic diet impact on epilepsy via gut microbiome 228 5. Potential mechanismsfor microbial Interactions with the ketogenic diet 236 6. Conclusion 241 References 242
viii Contents 9. Traumatic spinal cord injury and the contributions of the post-injury microbiome 251 Adam Μ. Hamilton and Timothy R. Sampson 1. Introduction 252 2. Remodeling of the gut microbiome after SCI 253 3. Interactions between the gut microbiome and SCI-induced neurogenic bowel 263 4. SCI-triggered local and systemic immuneresponses 265 5. Contributions of the microbiome to SChassociated inflammation in humans 267 6. Microbiome contributions to SCI-associated inflammation in experimental models 268 7. SCI microbiome association with gut permeability after injury 271 8. Microbiome manipulations with therapeutic potential for SCI recovery 272 9. Looking broadly into the future at microbiome effects on SCI 279 Acknowledgments 280 References 280
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| adam_txt |
Contents Contributors ix Introduction: Unraveling the complex contributions of indigenous microbes to neurological health and disease xi 1. Intersections of the microbiome and early neurodevelopment 1 Helen E. Vuong 1. Microbiota regulation of brain and behavior 2 2. Prenatal and early postnatal microbiota 3 3. Impact of microbiota on neurodevelopment: Considerations of the developmental origins of health and disease 7 4. Potential mechanisms of microbiota influences on neurodevelopment 14 5. Future directions 17 References 18 2. Microbiome influences on neuro-immune interactions in neurodegenerative disease 25 Kelly B. Menees, Brittney A. Otero, and Malú Gámez Tansey 1. Introduction 26 2. Microbiome influences on microglia 27 3. Microbiome influences on astrocytes 28 4. Microbiome influences on other immune cells 30 5. Gut microbiome studies in human populations 31 6. Gut microbiome studies in model organisms of aging or neurological disease 7. Blood brain barrier (BBB) 35 36 8. Vagus nerve 37 9. Mediators of gut/brain crosstalk 38 10. Therapeutic potential of probiotics and prebiotics to treat neurodegenerative disease 45 11. Future challenges/directions 46 Acknowledgments 47 Conflict of interests 47 References 47 V
Contents vi 3. The many genomes of Parkinson's disease 59 Haydeh Payami 1. Holistic view 60 2. Hologenome 61 3. PD and the microbiome 69 4. Concluding remarks 75 Funding sources 75 References 76 4. Intestinal microbiota and neuroinflammation in Parkinson's disease: At the helm of the gut-brain axis 81 Richard A. Manfready, Christopher G. Goetz, and Ali Keshavarzian 1. Introduction: Intestinal microbiota in health anddisease 82 2. Microbial signatures and their significance in Parkinson's disease 84 3. Neuroprotection by short-chain fatty acids 87 4. Microbial effects on neuroinflammation 88 5. Environmental and dietary influences 89 6. Common medications and microbiota 90 7. Therapeutic strategies 91 8. Conclusions 93 References 94 5. The emerging role of the microbiome in Alzheimer's disease 101 Caroline Wasén, Ella Simonsen, Millicent N. Ekwudo, Martin R. Profant, and Laura Μ. Cox 1. Alzheimer's disease ’02 2. The gut microbiota influence health and disease in aging 103 3. The gut microbiota of patients with Alzheimer's disease 104 4. Antibiotics and Alzheimer's disease '05 5. The gut microbiota of murine models of Alzheimer's disease 107 6. The gut microbiota and the immune system in Alzheimer's disease ' 13 7. Interactions between the diet, the microbiota, and Alzheimer's disease 11 7 8. Prebiotics ’ 20 9. Microbial mediators associated with Alzheimer's disease ’21 10. Potential use of probiotics for the treatment of AD 123 References 131
Contents vii 6, The microbiota-gut-brain axis in Huntington's disease 141 Chloe J. Love, Bethany A. Masson, Carolina Gubert, and Anthony J. Hannan 1. Microbiota-gut-brain axis 142 2. Gut microbiota disruption 149 3. Huntington's disease 152 4. The gut microbiota in HD 157 5. Gut microbiota and HD motor symptoms 158 6. Gut microbiota and HD-induced weightloss 159 7. Gut microbiota and cognition in HD 161 8. Gut microbiota and immune function inHD 162 9. Microbiota-gut-brain axis in HD 163 10. Gut microbiota and HD sexual dimorphism 165 11. Environment 166 12. Limitations 170 13. Conclusion 170 171 References 7. Role of the gut microbiome in multiple sclerosis: From etiology to therapeutics 185 Shailesh K. Shahi, Meeta Yadav, Sudeep Ghimire, and Ashutosh K. Mangalam 1. Microbiome associations studies in MS 187 2. Mechanisms of gut dysbiosis 193 3. Influence of diet on the pathobiology of MS 199 4. Targeting gut bacteria to treat multiple sclerosis 199 5. Conclusions 207 Acknowledgments 208 Conflict of interest statement 208 References 208 8. Interactions between the gut microbiome and ketogenic diet in refractory epilepsy 217 Ezgi Özcan, Gregory R. Lum, and Elaine Y. Hsiao 1. Introduction to epilepsy 2. Increasing interest in the microbiome and epilepsy 218 219 3. Ketogenic diet andepilepsy 224 4. Ketogenic diet impact on epilepsy via gut microbiome 228 5. Potential mechanismsfor microbial Interactions with the ketogenic diet 236 6. Conclusion 241 References 242
viii Contents 9. Traumatic spinal cord injury and the contributions of the post-injury microbiome 251 Adam Μ. Hamilton and Timothy R. Sampson 1. Introduction 252 2. Remodeling of the gut microbiome after SCI 253 3. Interactions between the gut microbiome and SCI-induced neurogenic bowel 263 4. SCI-triggered local and systemic immuneresponses 265 5. Contributions of the microbiome to SChassociated inflammation in humans 267 6. Microbiome contributions to SCI-associated inflammation in experimental models 268 7. SCI microbiome association with gut permeability after injury 271 8. Microbiome manipulations with therapeutic potential for SCI recovery 272 9. Looking broadly into the future at microbiome effects on SCI 279 Acknowledgments 280 References 280 |
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| spelling | Microbiome in neurological disease edited by Timothy R. Sampson (Department of Cell Biology, Emory University School of Medicine, Atlanta, GA, United States) First edition Cambridge, MA ; San Diego, CA Academic Press, an imprint of Elsevier 2022 xvi, 290 Seiten Illustrationen txt rdacontent n rdamedia nc rdacarrier International review of neurobiology volume 167 Mikroflora (DE-588)4169816-2 gnd rswk-swf Nervenkrankheit (DE-588)1068493003 gnd rswk-swf Darmflora (DE-588)4148805-2 gnd rswk-swf Nervenkrankheit (DE-588)1068493003 s Mikroflora (DE-588)4169816-2 s DE-604 Darmflora (DE-588)4148805-2 s Sampson, Timothy R. edt Erscheint auch als Online-Ausgabe 978-0-323-99175-9 International review of neurobiology volume 167 (DE-604)BV002534817 167 Digitalisierung UB Regensburg - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=034027565&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Microbiome in neurological disease International review of neurobiology Mikroflora (DE-588)4169816-2 gnd Nervenkrankheit (DE-588)1068493003 gnd Darmflora (DE-588)4148805-2 gnd |
| subject_GND | (DE-588)4169816-2 (DE-588)1068493003 (DE-588)4148805-2 |
| title | Microbiome in neurological disease |
| title_auth | Microbiome in neurological disease |
| title_exact_search | Microbiome in neurological disease |
| title_exact_search_txtP | Microbiome in neurological disease |
| title_full | Microbiome in neurological disease edited by Timothy R. Sampson (Department of Cell Biology, Emory University School of Medicine, Atlanta, GA, United States) |
| title_fullStr | Microbiome in neurological disease edited by Timothy R. Sampson (Department of Cell Biology, Emory University School of Medicine, Atlanta, GA, United States) |
| title_full_unstemmed | Microbiome in neurological disease edited by Timothy R. Sampson (Department of Cell Biology, Emory University School of Medicine, Atlanta, GA, United States) |
| title_short | Microbiome in neurological disease |
| title_sort | microbiome in neurological disease |
| topic | Mikroflora (DE-588)4169816-2 gnd Nervenkrankheit (DE-588)1068493003 gnd Darmflora (DE-588)4148805-2 gnd |
| topic_facet | Mikroflora Nervenkrankheit Darmflora |
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