Junk DNA: A Journey Through the Dark Matter of the Genome
For decades after the identification of the structure of DNA, scientists focused only on genes, the regions of the genome that contain codes for the production of proteins. Other regions that make up 98 percent of the human genome were dismissed as "junk," sequences that serve no purpose....
Gespeichert in:
| 1. Verfasser: | |
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| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
New York, NY
Columbia University Press
[2015]
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| Schlagworte: | |
| Online-Zugang: | DE-1046 DE-1043 DE-858 DE-859 DE-860 DE-739 URL des Erstveröffentlichers |
| Zusammenfassung: | For decades after the identification of the structure of DNA, scientists focused only on genes, the regions of the genome that contain codes for the production of proteins. Other regions that make up 98 percent of the human genome were dismissed as "junk," sequences that serve no purpose. But researchers have recently discovered variations and modulations in this junk DNA that are involved with a number of intractable diseases. Our increasing knowledge of junk DNA has led to innovative research and treatment approaches that may finally ameliorate some of these conditions.Junk DNA can play vital and unanticipated roles in the control of gene expression, from fine-tuning individual genes to switching off entire chromosomes. These functions have forced scientists to revisit the very meaning of the word "gene" and have engendered a spirited scientific battle over whether or not this genomic "nonsense" is the source of human biological complexity. Drawing on her experience with leading scientific investigators in Europe and North America, Nessa Carey provides a clear and compelling introduction to junk DNA and its critical involvement in phenomena as diverse as genetic diseases, viral infections, sex determination in mammals, and evolution. We are only now unlocking the secrets of junk DNA, and Nessa Carey's book is an essential resource for navigating the history and controversies of this fast-growing, hotly disputed field |
| Beschreibung: | Description based on online resource; title from PDF title page (publisher's Web site, viewed 05. Dez 2022) |
| Beschreibung: | 1 Online-Ressource (360 Seiten) 61 b&w illustrations |
| ISBN: | 9780231539418 |
| DOI: | 10.7312/care17084 |
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| spelling | Carey, Nessa Verfasser aut Junk DNA A Journey Through the Dark Matter of the Genome Nessa Carey New York, NY Columbia University Press [2015] © 2015 1 Online-Ressource (360 Seiten) 61 b&w illustrations txt rdacontent c rdamedia cr rdacarrier Description based on online resource; title from PDF title page (publisher's Web site, viewed 05. Dez 2022) For decades after the identification of the structure of DNA, scientists focused only on genes, the regions of the genome that contain codes for the production of proteins. Other regions that make up 98 percent of the human genome were dismissed as "junk," sequences that serve no purpose. But researchers have recently discovered variations and modulations in this junk DNA that are involved with a number of intractable diseases. Our increasing knowledge of junk DNA has led to innovative research and treatment approaches that may finally ameliorate some of these conditions.Junk DNA can play vital and unanticipated roles in the control of gene expression, from fine-tuning individual genes to switching off entire chromosomes. These functions have forced scientists to revisit the very meaning of the word "gene" and have engendered a spirited scientific battle over whether or not this genomic "nonsense" is the source of human biological complexity. Drawing on her experience with leading scientific investigators in Europe and North America, Nessa Carey provides a clear and compelling introduction to junk DNA and its critical involvement in phenomena as diverse as genetic diseases, viral infections, sex determination in mammals, and evolution. We are only now unlocking the secrets of junk DNA, and Nessa Carey's book is an essential resource for navigating the history and controversies of this fast-growing, hotly disputed field In English SCIENCE / Life Sciences / Genetics & Genomics bisacsh Intron (DE-588)4162195-5 gnd rswk-swf Genetik (DE-588)4071711-2 gnd rswk-swf Genetischer Fingerabdruck (DE-588)4245149-8 gnd rswk-swf RNS (DE-588)4076759-0 gnd rswk-swf DNS (DE-588)4070512-2 gnd rswk-swf Proteinsynthese (DE-588)4261878-2 gnd rswk-swf Exon (DE-588)4201879-1 gnd rswk-swf Epigenetik (DE-588)7566079-9 gnd rswk-swf Genetik (DE-588)4071711-2 s Proteinsynthese (DE-588)4261878-2 s DNS (DE-588)4070512-2 s RNS (DE-588)4076759-0 s Epigenetik (DE-588)7566079-9 s Intron (DE-588)4162195-5 s Exon (DE-588)4201879-1 s DE-604 Genetischer Fingerabdruck (DE-588)4245149-8 s Erscheint auch als Druck-Ausgabe 9780231170840 https://doi.org/10.7312/care17084 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Carey, Nessa Junk DNA A Journey Through the Dark Matter of the Genome SCIENCE / Life Sciences / Genetics & Genomics bisacsh Intron (DE-588)4162195-5 gnd Genetik (DE-588)4071711-2 gnd Genetischer Fingerabdruck (DE-588)4245149-8 gnd RNS (DE-588)4076759-0 gnd DNS (DE-588)4070512-2 gnd Proteinsynthese (DE-588)4261878-2 gnd Exon (DE-588)4201879-1 gnd Epigenetik (DE-588)7566079-9 gnd |
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| title | Junk DNA A Journey Through the Dark Matter of the Genome |
| title_auth | Junk DNA A Journey Through the Dark Matter of the Genome |
| title_exact_search | Junk DNA A Journey Through the Dark Matter of the Genome |
| title_exact_search_txtP | Junk DNA A Journey Through the Dark Matter of the Genome |
| title_full | Junk DNA A Journey Through the Dark Matter of the Genome Nessa Carey |
| title_fullStr | Junk DNA A Journey Through the Dark Matter of the Genome Nessa Carey |
| title_full_unstemmed | Junk DNA A Journey Through the Dark Matter of the Genome Nessa Carey |
| title_short | Junk DNA |
| title_sort | junk dna a journey through the dark matter of the genome |
| title_sub | A Journey Through the Dark Matter of the Genome |
| topic | SCIENCE / Life Sciences / Genetics & Genomics bisacsh Intron (DE-588)4162195-5 gnd Genetik (DE-588)4071711-2 gnd Genetischer Fingerabdruck (DE-588)4245149-8 gnd RNS (DE-588)4076759-0 gnd DNS (DE-588)4070512-2 gnd Proteinsynthese (DE-588)4261878-2 gnd Exon (DE-588)4201879-1 gnd Epigenetik (DE-588)7566079-9 gnd |
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