Sex and gender differences in neurological disease:
Saved in:
| Other Authors: | , , , |
|---|---|
| Format: | Book |
| Language: | English |
| Published: |
Cambridge, MA ; San Diego, CA
Academic Press, an imprint of Elsevier
2022
|
| Edition: | First edition |
| Series: | International review of neurobiology
volume 164 |
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Physical Description: | xv, 375 Seiten Illustrationen, Diagramme |
| ISBN: | 9780323915892 |
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| 245 | 1 | 0 | |a Sex and gender differences in neurological disease |c edited by Elena Moro (Grenoble Alpes University, CHU of Grenoble, Division of Neurology, Grenoble Institute of Neurosciences, Grenoble, France), Gennarina Arabia (Magna Graecia University, Movement Disorders Center, Neurology Unit, Catanzaro, Italy), Maria Carmela Tartaglia (Memory Clinic, Krembil Brain Institute, University Health Network; Canadian Concussion Centre, Krembil Brain Institute, University Health Network; Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Canada), Maria Teresa Ferretti (Women's Brain Project, Guntershausen, Switzerland) |
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Contents Contributors ix Introduction xiii 1. History and development of sex- and gender sensitive medicine (SGSM) 1 Eva Becher and Sabine Oertelt-Prigione 1. What is sex- and gender-sensitive medicine 3 2. But then, what are sex and gender exactly? 4 3. Aims and clinical relevance of SGSM 5 4. Ancient history 7 5. How it started 7 6. Milestones of the establishment of sex- and gender-sensitive medicine 8 7. The situation today 19 8. Outlook 22 9. Key points/take home messages 22 References 22 2. Biological underpinnings of sex differences in neurological disorders 27 Katarzyna Winek, Yonat Tzur, and Hermona Soreq 1. How different are neurological diseases in males and females?—The brain perspective 28 2. Peripheral sex-derived differences affectingthe CNS 34 3. Sex hormones and the CNS 40 4. Genetics of sex differences and their impact on the brain 43 5. Epigenetics of sex differences 47 6. Recently identified factors influencing neurological disease with sex-specific signatures 50 7. Conclusion 55 Acknowledgment 56 References 56 3. Sex differences in neurovascular disorders 69 Cheryl Cárcel, Valeria Caso, Diana Aguiar de Sousa, and Else Charlotte Sandset 1. Introduction 70 2. Risk factors 71 v|
vi Contents 3. Symptom presentation 76 4. Ischemic stroke 77 5. Intracerebral hemorrhage, intracranial aneurysms and subarachnoid 84 hemorrhage 6. Cerebral vein thrombosis 86 7, Women in clinical stroke trials 89 8. Conclusion 90 Keypoints 90 References 91 4. Sex and gender differences in movement disorders: Parkinson's disease, essential tremor, dystoniaandchorea 101 Gennarina Arabia, Antonio De Martino, and Elena Moro 1. Sex and gender-specific differences inParkinson's disease 102 2. Sex and gender-specific differences in essential tremor 108 3. Sex and gender-specific differences in dystonia 110 4. Sex and gender-specific differences in chorea: Huntington'sdisease 114 5. Conclusions 118 6. Key points 118 References 118 5. Sex and gender differences in autoimmune demyelinating CNS disorders: Multiple sclerosis (MS), neuromyelitis optica spectrum disorder (NMOSD) and myelin-oligodendrocyte-glycoprotein antibody associated disorder (MOGAD) 129 Lara Diem, Helly Hammer, Robert Hoepner, Max Pistor, Jana Remiinger, and Anke Salmen 1. Background: Pathophysiology of CNS autoimmunity in the context of 130 sex-specific differences 2. Multiple sclerosis (MS) 137 3. Neuromyelitis optica spectrum disorder (NMOSD) and myelin- oligodendrocyte-glycoprotein antibodyassociated disorder (MOGAD) 144 4. Immunotherapies in the context of sex differences 153 5. Conclusions 165 References 167 6. Sex and gender differences in dementia 179 Patrick Salwierz, Carly Davenport, Vishaal Sumra, Μ. Florencia lülita, Maria Teresa Ferretti, and Maria Carmela Tartaglia 1. Sex and gender differences in
Alzheimer's disease 180 2. Sex and gender differences in vascular cognitive impairment/vascular dementia 191
vii Contents 3. Sex and gender differences in Parkinson's disease/dementia with Lewy bodies 198 4. Sex and gender differencesinfrontotemporal dementia 208 References 214 7. Sex and gender differences in epilepsy 235 Lauren Hophing, Paulina Kyriakopoulos, and Esther Bui 1. Introduction 236 2. Sex hormones and epilepsy 237 3. Sex hormone changes and regulationduring the lifespan 238 4. Catamenial epilepsy 239 5. Hormonal influences of antiseizuremedications 245 6. Sexual and reproductive dysfunctionin epilepsy 249 7. Special populations 251 8. Pregnancy and epilepsy 253 9. Menopause and bone health 265 10. Summary 268 References 268 Further reading 276 8. Sex and gender differences in pain 277 Natalie R. Osborne and Karen D. Davis 1. Introduction 278 2. Part I: How does pain differ by sex and gender? 280 3. Part II: What causes sex and gender differences in pain? 284 4. Part III: Why do sex and gender differences in pain matter? 295 References 298 9. Sex and age differences in migraine treatment and management strategies 309 Elena R. Lebedeva 1. Introduction 310 2. Part I: Management of migraine in girls and boys 3-І 7 years old 313 3. Part II: Management of migraine in women 18-40 years old 317 4. Part III: Management of menstrual migraine 320 5. Part IV: Management of migraine in pregnancy 324 6. Part V: Management of migraine during lactation 327 7. Part VI: Management of migraine in perimenopause 330 8. Part VII: Management of migraine in menopause and post-menopause 334 9. Part VIII: Management of migraine in men 18-50 years old 339 10. Part IX: Management of migraine in
men 50 years old 342
viii Contents 11. Conclusions 345 12. Key points 345 References 346 10. Sex and gender differences in mild traumatic brain injury/ concussion 349 Samaneh Chaychi, Eve Valera, and Maria Carmela Tartaglia 1. Mild traumatic brain injury/concussion 350 2. Sex-related differences in mild traumatic braininjury/concussion 351 3. Possible mechanisms underlying sex differences in concussion 354 4. Different mechanisms of injury leading to mild traumatic brain injury/corieussion References 359 366 |
| adam_txt |
Contents Contributors ix Introduction xiii 1. History and development of sex- and gender sensitive medicine (SGSM) 1 Eva Becher and Sabine Oertelt-Prigione 1. What is sex- and gender-sensitive medicine 3 2. But then, what are sex and gender exactly? 4 3. Aims and clinical relevance of SGSM 5 4. Ancient history 7 5. How it started 7 6. Milestones of the establishment of sex- and gender-sensitive medicine 8 7. The situation today 19 8. Outlook 22 9. Key points/take home messages 22 References 22 2. Biological underpinnings of sex differences in neurological disorders 27 Katarzyna Winek, Yonat Tzur, and Hermona Soreq 1. How different are neurological diseases in males and females?—The brain perspective 28 2. Peripheral sex-derived differences affectingthe CNS 34 3. Sex hormones and the CNS 40 4. Genetics of sex differences and their impact on the brain 43 5. Epigenetics of sex differences 47 6. Recently identified factors influencing neurological disease with sex-specific signatures 50 7. Conclusion 55 Acknowledgment 56 References 56 3. Sex differences in neurovascular disorders 69 Cheryl Cárcel, Valeria Caso, Diana Aguiar de Sousa, and Else Charlotte Sandset 1. Introduction 70 2. Risk factors 71 v|
vi Contents 3. Symptom presentation 76 4. Ischemic stroke 77 5. Intracerebral hemorrhage, intracranial aneurysms and subarachnoid 84 hemorrhage 6. Cerebral vein thrombosis 86 7, Women in clinical stroke trials 89 8. Conclusion 90 Keypoints 90 References 91 4. Sex and gender differences in movement disorders: Parkinson's disease, essential tremor, dystoniaandchorea 101 Gennarina Arabia, Antonio De Martino, and Elena Moro 1. Sex and gender-specific differences inParkinson's disease 102 2. Sex and gender-specific differences in essential tremor 108 3. Sex and gender-specific differences in dystonia 110 4. Sex and gender-specific differences in chorea: Huntington'sdisease 114 5. Conclusions 118 6. Key points 118 References 118 5. Sex and gender differences in autoimmune demyelinating CNS disorders: Multiple sclerosis (MS), neuromyelitis optica spectrum disorder (NMOSD) and myelin-oligodendrocyte-glycoprotein antibody associated disorder (MOGAD) 129 Lara Diem, Helly Hammer, Robert Hoepner, Max Pistor, Jana Remiinger, and Anke Salmen 1. Background: Pathophysiology of CNS autoimmunity in the context of 130 sex-specific differences 2. Multiple sclerosis (MS) 137 3. Neuromyelitis optica spectrum disorder (NMOSD) and myelin- oligodendrocyte-glycoprotein antibodyassociated disorder (MOGAD) 144 4. Immunotherapies in the context of sex differences 153 5. Conclusions 165 References 167 6. Sex and gender differences in dementia 179 Patrick Salwierz, Carly Davenport, Vishaal Sumra, Μ. Florencia lülita, Maria Teresa Ferretti, and Maria Carmela Tartaglia 1. Sex and gender differences in
Alzheimer's disease 180 2. Sex and gender differences in vascular cognitive impairment/vascular dementia 191
vii Contents 3. Sex and gender differences in Parkinson's disease/dementia with Lewy bodies 198 4. Sex and gender differencesinfrontotemporal dementia 208 References 214 7. Sex and gender differences in epilepsy 235 Lauren Hophing, Paulina Kyriakopoulos, and Esther Bui 1. Introduction 236 2. Sex hormones and epilepsy 237 3. Sex hormone changes and regulationduring the lifespan 238 4. Catamenial epilepsy 239 5. Hormonal influences of antiseizuremedications 245 6. Sexual and reproductive dysfunctionin epilepsy 249 7. Special populations 251 8. Pregnancy and epilepsy 253 9. Menopause and bone health 265 10. Summary 268 References 268 Further reading 276 8. Sex and gender differences in pain 277 Natalie R. Osborne and Karen D. Davis 1. Introduction 278 2. Part I: How does pain differ by sex and gender? 280 3. Part II: What causes sex and gender differences in pain? 284 4. Part III: Why do sex and gender differences in pain matter? 295 References 298 9. Sex and age differences in migraine treatment and management strategies 309 Elena R. Lebedeva 1. Introduction 310 2. Part I: Management of migraine in girls and boys 3-І 7 years old 313 3. Part II: Management of migraine in women 18-40 years old 317 4. Part III: Management of menstrual migraine 320 5. Part IV: Management of migraine in pregnancy 324 6. Part V: Management of migraine during lactation 327 7. Part VI: Management of migraine in perimenopause 330 8. Part VII: Management of migraine in menopause and post-menopause 334 9. Part VIII: Management of migraine in men 18-50 years old 339 10. Part IX: Management of migraine in
men 50 years old 342
viii Contents 11. Conclusions 345 12. Key points 345 References 346 10. Sex and gender differences in mild traumatic brain injury/ concussion 349 Samaneh Chaychi, Eve Valera, and Maria Carmela Tartaglia 1. Mild traumatic brain injury/concussion 350 2. Sex-related differences in mild traumatic braininjury/concussion 351 3. Possible mechanisms underlying sex differences in concussion 354 4. Different mechanisms of injury leading to mild traumatic brain injury/corieussion References 359 366 |
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| spelling | Sex and gender differences in neurological disease edited by Elena Moro (Grenoble Alpes University, CHU of Grenoble, Division of Neurology, Grenoble Institute of Neurosciences, Grenoble, France), Gennarina Arabia (Magna Graecia University, Movement Disorders Center, Neurology Unit, Catanzaro, Italy), Maria Carmela Tartaglia (Memory Clinic, Krembil Brain Institute, University Health Network; Canadian Concussion Centre, Krembil Brain Institute, University Health Network; Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Canada), Maria Teresa Ferretti (Women's Brain Project, Guntershausen, Switzerland) First edition Cambridge, MA ; San Diego, CA Academic Press, an imprint of Elsevier 2022 xv, 375 Seiten Illustrationen, Diagramme txt rdacontent n rdamedia nc rdacarrier International review of neurobiology volume 164 Geschlechtsunterschied (DE-588)4071781-1 gnd rswk-swf Nervenkrankheit (DE-588)1068493003 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Nervenkrankheit (DE-588)1068493003 s Geschlechtsunterschied (DE-588)4071781-1 s DE-604 Moro, Elena edt Arabia, Gennarina edt Tartaglia, Maria Carmela edt Ferretti, Maria Teresa (DE-588)1238190014 edt Erscheint auch als Online-Ausgabe 978-0-323-91590-8 International review of neurobiology volume 164 (DE-604)BV002534817 164 Digitalisierung UB Regensburg - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=033856067&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
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| title | Sex and gender differences in neurological disease |
| title_auth | Sex and gender differences in neurological disease |
| title_exact_search | Sex and gender differences in neurological disease |
| title_exact_search_txtP | Sex and gender differences in neurological disease |
| title_full | Sex and gender differences in neurological disease edited by Elena Moro (Grenoble Alpes University, CHU of Grenoble, Division of Neurology, Grenoble Institute of Neurosciences, Grenoble, France), Gennarina Arabia (Magna Graecia University, Movement Disorders Center, Neurology Unit, Catanzaro, Italy), Maria Carmela Tartaglia (Memory Clinic, Krembil Brain Institute, University Health Network; Canadian Concussion Centre, Krembil Brain Institute, University Health Network; Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Canada), Maria Teresa Ferretti (Women's Brain Project, Guntershausen, Switzerland) |
| title_fullStr | Sex and gender differences in neurological disease edited by Elena Moro (Grenoble Alpes University, CHU of Grenoble, Division of Neurology, Grenoble Institute of Neurosciences, Grenoble, France), Gennarina Arabia (Magna Graecia University, Movement Disorders Center, Neurology Unit, Catanzaro, Italy), Maria Carmela Tartaglia (Memory Clinic, Krembil Brain Institute, University Health Network; Canadian Concussion Centre, Krembil Brain Institute, University Health Network; Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Canada), Maria Teresa Ferretti (Women's Brain Project, Guntershausen, Switzerland) |
| title_full_unstemmed | Sex and gender differences in neurological disease edited by Elena Moro (Grenoble Alpes University, CHU of Grenoble, Division of Neurology, Grenoble Institute of Neurosciences, Grenoble, France), Gennarina Arabia (Magna Graecia University, Movement Disorders Center, Neurology Unit, Catanzaro, Italy), Maria Carmela Tartaglia (Memory Clinic, Krembil Brain Institute, University Health Network; Canadian Concussion Centre, Krembil Brain Institute, University Health Network; Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Canada), Maria Teresa Ferretti (Women's Brain Project, Guntershausen, Switzerland) |
| title_short | Sex and gender differences in neurological disease |
| title_sort | sex and gender differences in neurological disease |
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