Holdings: Biomaterial science

Biomaterial science: anatomy and physiology aspects

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Bibliographic Details
Main Author:	Aguilar, Ludwig Erik (Author)
Format:	Book
Language:	English
Published:	Berlin ; Boston De Gruyter [2022]
Series:	De Gruyter graduate
Subjects:	Biomaterial Biomaterialien Anatomie Physiologie TB: Textbook
Online Access:	https://www.degruyter.com/isbn/9783110655353 Inhaltsverzeichnis
Physical Description:	XVII, 458 Seiten Illustrationen 24 cm x 17 cm
ISBN:	9783110655353 3110655357

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Record in the Search Index

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adam_text	CONTENTS ABOUT THE AUTHORS - VII PREFACE - IX GOALS - XI CHAPTER 1 IMPORTANCE OF HUMAN ANATOMY AND PHYSIOLOGY IN BIOMATERIAL SCIENCE - 1 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 1.9 1.10 BIOMATERIALS ---- 2 BIOMATERIALS FOR THE INTEGUMENTARY SYSTEM ---- 3 BIOMATERIALS FOR THE MUSCULOSKELETAL SYSTEM - 5 BIOMATERIALS FOR THE CARDIOVASCULAR SYSTEM - 9 BIOMATERIALS FOR THE NERVOUS SYSTEM - 13 BIOMATERIALS FOR THE DIGESTIVE SYSTEM ---- 18 BIOMATERIALS FOR THE REPRODUCTIVE SYSTEM - 23 BIOMATERIALS FOR THE URINARY SYSTEM ---- 26 BIOMATERIALS FOR THE SENSORY ORGANS (EYES AND EARS) - 29 CONCLUSION ---- 32 REFERENCES ---- 33 CHAPTER 2 CLASSIFICATION OF BIOMATERIALS - 45 2.1 2.2 2.2.1 2.2.2 2.2.3 2.3 2.3.1 2.3.2 2.3.3 2.3.4 2.4 2.4.1 2.4.2 2.4.3 2.5 DESCRIPTION OF DIFFERENT CLASSES OF BIOMATERIALS - 45 NATURAL BIOMATERIALS - 46 POLYSACCHARIDES USED AS BIOMATERIALS - 46 POLYPEPTIDES USED AS BIOMATERIALS - 55 PHENOLICS USED AS BIOMATERIALS - 62 SYNTHETIC BIOMATERIALS - 67 SYNTHETIC POLYMERS (NONBIODEGRADABLE) - 67 SYNTHETIC POLYMERS (BIODEGRADABLE AND BIORESORBABLE) - 79 BIOCERAMICS - 90 METALLIC BIOMATERIALS - 100 COMPOSITE BIOMATERIALS - 110 POLYMER-CERAMIC COMPOSITES - 111 CERAMIC-METAL COMPOSITES ---- 112 METAL-POLYMER COMPOSITES - 113 CONCLUSION ---- 115 REFERENCES - 115 XIV - CONTENTS CHAPTER 3 METHODS IN BIOMATERIALS YY - 151 3.1 3.2 3.2.1 3.2.2 3.2.3 BIOMATERIAL SYNTHESIS AND FABRICATION YY - 151 ELECTROSPINNING - 152 BASICS OF THE ELECTROSPINNING SETUP YY - 152 EFFECT OF POLYMER PROPERTIES (MOLECULAR WEIGHT DISTRIBUTION) YY - 154 EFFECT OF POLYMER SOLUTION PROPERTIES (VISCOSITY, CONDUCTIVITY, SURFACE TENSION) ON ELECTROSPUN FIBERS - 154 3.2.4 3.2.5 3.2.6 EFFECT OF APPLIED VOLTAGE AND FEED RATE - 155 EFFECT OF DISTANCE OF NOZZLE TO COLLECTOR YY - 155 EFFECT OF DISTANCE OF AMBIENT PARAMETERS (TEMPERATURE, HUMIDITY IN THE CHAMBER) YY - 156 3.2.7 3.2.8 3.2.9 3.2.10 3.3 3.3.1 3.3.2 3.4 3.4.1 3.5 3.5.1 3.5.2 3.5.3 3.5.4 3.5.5 3.5.6 3.5.7 3.6 3.6.1 3.6.2 3.6.3 3.6.4 3.7 3.7.1 3.7.2 3.7.3 3.8 3.8.1 EFFECT OF MOTION OF THE NOZZLE AND COLLECTOR ROTATION ---- 156 EFFECT OF NOZZLE GAUGE - 156 CHALLENGES IN ELECTROSPINNING ---- 157 ELECTROSPINNING MODIFICATIONS - 157 3D BIOPRINTING ---- 163 BASICS OF 3D BIOPRINTING ---- 163 BIOINK ---- 165 3D METAL AND CERAMIC PRINTING - 171 SELECTIVE LASER SINTERING - 171 COATING METHODS ---- 172 DIP COATING ---- 172 SPIN COATING ---- 173 SPRAY COATING (COLD SPRAYING) - 174 ELECTROSPRAYING ---- 174 ELECTROPOLYMERIZATION COATING - 175 UV-LIGHT-ASSISTED COATING - 175 COATING METHOD CHALLENGES ---- 176 HYDROGEL PREPARATIONS - 177 PHYSICAL CROSS-LINKING ---- 177 CHEMICAL CROSS-LINKING (POLYMER GRAFTING) - 179 UNIQUE HYDROGEL ITERATIONS USED IN BIOMEDICINE ---- 180 HYDROGEL PREPARATION CHALLENGES - 181 INORGANIC AND ORGANIC NANOPARTICLES PREPARATIONS - 182 ORGANIC NANOPARTICLES ---- 182 INORGANIC NANOPARTICLES - 185 CHALLENGES IN NANOPARTICLES SYNTHESIS - 190 BIOCERAMIC SYNTHESIS METHODS ---- 191 WET CHEMICAL PRECIPITATION SYNTHESIS OF BIOCERAMICS (HYDROXYAPATITE) - 191 3.8.2 SOL-GEL METHOD IN THE PREPARATION OF BULK POROUS BIOCERAMIC ---- 192 CONTENTS - XV 3.8.3 3.8.4 3.8.5 3.8.6 3.9 3.9.1 3.9.2 3.9.3 3.9.4 3.9.5 3.9.6 3.9.7 3.10 HYDROTHERMAL METHOD FOR CREATING CALCIUM OXIDE ---- 192 SOLID-STATE REACTIONS IN THE PREPARATION OF SYNTHETIC APATITE ---- 193 MELTING-QUENCHING METHOD FOR BIOGLASS PREPARATION ---- 193 CHALLENGES IN BIOCERAMIC SYNTHESIS AND MANUFACTURING ---- 194 FABRICATION METHODS OF BIOMEDICAL-GRADE ALLOYS - 194 THERMOMECHANICAL PROCESS (TMP) ---- 195 HOT ISO-STATIC PRESSING (HIP) ---- 195 POWDER METALLURGY (SINTERING) ---- 196 SUPERPLASTIC DEFORMATION AND ISOTHERMAL FORGING - 196 ELASTIC METAL ALLOY MANUFACTURING (NITINOT) ---- 197 POST-PROCESSING OF METALLIC ALLOYS TO BE USED IN BIOMEDICINE - 198 CHALLENGES IN METAL FABRICATION FOR BIOMEDICAL APPLICATIONS - 199 CONCLUSIONS - 199 REFERENCES ---- 200 CHAPTER 4 BIOMATERIALS AND THE HUMAN IMMUNE SYSTEM - 223 4.1 4.1.1 4.1.2 4.1.3 4.1.4 THE HUMAN IMMUNE RESPONSE TOWARD BIOMATERIALS - 223 THE BASICS OF THE HUMAN IMMUNE SYSTEM - 223 CLASSES OF IMMUNE CELLS ---- 224 COMMUNICATION BETWEEN IMMUNE CELLS ---- 228 IMMUNOGLOBULINS AND THEIR ROLE TO IMMUNE RESPONSE (ANTIBODY IMMUNE RESPONSE) - 229 4.1.5 THE MAJOR HISTOCOMPATIBILITY COMPLEX AND ACTIVATED COMPLEMENT PROTEINS (PROTEINS ROLE IN IMMUNITY) ---- 230 4.2 4.2.1 4.2.2 4.3 THE BODY S GENERAL RESPONSE TOWARD BIOMATERIALS - 232 FOREIGN BODY RESPONSE ---- 232 INFLAMMATION AND WOUND HEALING PROCESS - 234 THE BODY S RESPONSE TOWARD DIFFERENT CLASSES OF BIOMATERIALS AND BIOMEDICAL DEVICES - 235 4.3.1 4.3.2 4.3.3 4.4 4.5 4.5.1 METALLIC MATERIALS AND THE IMMUNE SYSTEM - 235 CERAMIC MATERIALS AND THE IMMUNE SYSTEM - 239 POLYMERIC MATERIALS AND THE IMMUNE SYSTEM ---- 239 IMMUNE RESPONSES TO NANOMATERIALS - 242 IMMUNE MODULATION TOOLS IN BIOMATERIALS - 244 PHYSICAL MODIFICATIONS (SURFACE TOPOGRAPHY AND HYDROPHILICITY) ---- 245 4.5.2 4.5.3 4.6 CHEMICAL MODIFICATIONS - 246 ACTIVE DELIVERY OF IMMUNE-MODULATORY COMPOUNDS ---- 247 CONCLUSION ---- 247 REFERENCES ---- 248 XVI - CONTENTS CHAPTER 5 BIOMATERIALS IN MEDICAL DEVICE DEVELOPMENT - 257 5.1 5.1.1 5.1.2 5.1.3 5.2 5.3 BIOMATERIALS ROLE IN MEDICAL DEVICE DEVELOPMENT ---- 257 CLASS 1 MEDICAL DEVICES ---- 257 CLASS II MEDICAL DEVICES ---- 258 CLASS III MEDICAL DEVICES - 259 BIOMATERIALS IN MEDICAL DEVICES (BIOSENSORS) - 259 BIOMATERIALS IN MEDICAL DEVICES (VASCULAR AND NONVASCULAR STENTS) ---- 261 5.3.1 5.3.2 5.4 5.4.1 5.4.2 5.5 VASCULAR STENTS ---- 262 NONVASCULAR STENTS - 266 BIOMATERIAL IN MEDICAL DEVICES (ARTIFICIAL HEART VALVES) ---- 270 MECHANICAL HEART VALVES - 272 TISSUE (ENGINEERED) HEART VALVES - 273 BIOMATERIAL IN MEDICAL DEVICES (BONE PROSTHESIS AND IMPLANTS) ---- 276 5.5.1 5.6 BONE PROSTHESIS (ARTIFICIAL HIP AND KNEE PROSTHESIS) - 277 BIOMATERIAL IN MEDICAL DEVICES (INTRAPERITONEAL MESH IMPLANTS) ---- 281 5.7 CONCLUSION ---- 284 REFERENCES ---- 285 CHAPTER 6 BIOMATERIALS IN CANCER TREATMENT - 297 6.1 6.2 6.2.1 CANCER AND ITS TREATMENT MODALITIES - 297 BIOMATERIALS IN CANCER CHEMOTHERAPY AND DIAGNOSTICS - 298 BIOMATERIAL DRUG DELIVERY SYSTEM FOR ENHANCING CHEMOTHERAPY EFFECTS ---- 298 6.2.2 6.2.3 6.2.4 6.2.5 6.2.6 6.3 6.4 6.4.1 6.4.2 6.4.3 6.4.4 6.4.5 6.4.6 6.5 PASSIVE TUMOR TARGETING - 302 ACTIVE TUMOR TARGETING ---- 304 THE PROTON SPONGE EFFECT - 305 NANOPARTICLE TRANSPORT ACROSS PHYSIOLOGICAL BARRIERS - 306 THERANOSTICS ---- 308 BIOMATERIALS USED IN SURGICAL INTERVENTION OF CANCER - 309 BIOMATERIALS USED IN HYPERTHERMIA TREATMENT OF CANCER - 313 MAGNETIC HYPERTHERMIA (NANOPARTICLE HEATING) - 316 MAGNETIC HYPERTHERMIA (BULK HEATING) - 318 PHOTODYNAMIC HYPERTHERMIA THERAPY - 320 METALLIC NANOPARTICLE-MEDIATED PTT - 321 CARBON-BASED NANOMATERIAL-MEDIATED PTT - 321 POLYMERIC MATERIAL-MEDIATED PTT ---- 321 BIOMATERIALS USED IN IMMUNOTHERAPY OF CANCER ---- 322 CONTENTS - XVII 6.5.1 6.5.2 6.5.3 6.6 IMPLANTABLE AND INJECTABLE BIOMATERIALS FOR IMMUNOTHERAPY ---- 322 TRANSDERMAL BIOMATERIALS FOR IMMUNOTHERAPY ---- 327 NANOPARTICLE TECHNOLOGY IN CANCER IMMUNOTHERAPY ---- 327 CONCLUSION ---- 329 REFERENCES ---- 330 CHAPTER 7 BIOMATERIALS IN DRUG DELIVERY ---- 345 7.1 7.1.1 7.1.2 7.1.3 7.1.4 7.1.5 7.1.6 7.2 7.2.1 7.2.2 7.2.3 7.2.4 PHARMACOLOGICAL CONCEPTS ---- 345 CONVENTIONAL DELIVERY METHODS FOR DRUG COMPOUNDS ---- 345 DRUG CLASSIFICATIONS - 347 DRUG-TO-DRUG INTERACTIONS ---- 349 ADVERSE AND SIDE EFFECTS OF THERAPEUTIC COMPOUNDS ---- 349 THERAPEUTIC RANGE ---- 350 PHARMACOKINETICS AND PHARMACODYNAMICS - 350 BIOMATERIALS ROLE IN DRUG DELIVERY ---- 351 BIOMATERIALS IN SYSTEMIC DRUG DELIVERY ---- 353 BIOMATERIALS IN ALTERNATIVE DRUG DELIVERY ---- 372 BIOMATERIALS IN GENE THERAPY AGENT DELIVERY ---- 379 BIOMATERIALS ALLOW DRUG DELIVERY CAPABILITIES IN MEDICAL DEVICES ---- 384 7.3 CONCLUSION ---- 385 REFERENCES ---- 385 CHAPTER 8 BIOMATERIALS IN TISSUE ENGINEERING - 399 8.1 8.1.1 8.1.2 8.1.3 8.1.4 8.2 8.2.1 8.2.2 8.2.3 8.3 TISSUE DISEASES AND REPAIR PROCESS ---- 399 PHYSICAL INJURIES AND ITS HEALING PROCESS ---- 400 DEGENERATIVE AND AUTOIMMUNE DISEASES - 403 PERFUSION AND ISCHEMIC ACCIDENTS ---- 407 CONGENITAL DEFECTS - 410 TISSUE ENGINEERING METHODS AND APPLICATIONS - 410 CONVENTIONAL TISSUE ENGINEERING - 412 STEM CELL BIOMATERIAL-BASED TISSUE ENGINEERING - 426 BIOMATERIALS IN CLOSED-LOOP TISSUE ENGINEERING METHODS - 432 CONCLUSIONS ---- 433 REFERENCES ---- 433 CONCLUDING REMARKS - 447 INDEX ---- 449
adam_txt	CONTENTS ABOUT THE AUTHORS - VII PREFACE - IX GOALS - XI CHAPTER 1 IMPORTANCE OF HUMAN ANATOMY AND PHYSIOLOGY IN BIOMATERIAL SCIENCE - 1 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 1.9 1.10 BIOMATERIALS ---- 2 BIOMATERIALS FOR THE INTEGUMENTARY SYSTEM ---- 3 BIOMATERIALS FOR THE MUSCULOSKELETAL SYSTEM - 5 BIOMATERIALS FOR THE CARDIOVASCULAR SYSTEM - 9 BIOMATERIALS FOR THE NERVOUS SYSTEM - 13 BIOMATERIALS FOR THE DIGESTIVE SYSTEM ---- 18 BIOMATERIALS FOR THE REPRODUCTIVE SYSTEM - 23 BIOMATERIALS FOR THE URINARY SYSTEM ---- 26 BIOMATERIALS FOR THE SENSORY ORGANS (EYES AND EARS) - 29 CONCLUSION ---- 32 REFERENCES ---- 33 CHAPTER 2 CLASSIFICATION OF BIOMATERIALS - 45 2.1 2.2 2.2.1 2.2.2 2.2.3 2.3 2.3.1 2.3.2 2.3.3 2.3.4 2.4 2.4.1 2.4.2 2.4.3 2.5 DESCRIPTION OF DIFFERENT CLASSES OF BIOMATERIALS - 45 NATURAL BIOMATERIALS - 46 POLYSACCHARIDES USED AS BIOMATERIALS - 46 POLYPEPTIDES USED AS BIOMATERIALS - 55 PHENOLICS USED AS BIOMATERIALS - 62 SYNTHETIC BIOMATERIALS - 67 SYNTHETIC POLYMERS (NONBIODEGRADABLE) - 67 SYNTHETIC POLYMERS (BIODEGRADABLE AND BIORESORBABLE) - 79 BIOCERAMICS - 90 METALLIC BIOMATERIALS - 100 COMPOSITE BIOMATERIALS - 110 POLYMER-CERAMIC COMPOSITES - 111 CERAMIC-METAL COMPOSITES ---- 112 METAL-POLYMER COMPOSITES - 113 CONCLUSION ---- 115 REFERENCES - 115 XIV - CONTENTS CHAPTER 3 METHODS IN BIOMATERIALS YY - 151 3.1 3.2 3.2.1 3.2.2 3.2.3 BIOMATERIAL SYNTHESIS AND FABRICATION YY - 151 ELECTROSPINNING - 152 BASICS OF THE ELECTROSPINNING SETUP YY - 152 EFFECT OF POLYMER PROPERTIES (MOLECULAR WEIGHT DISTRIBUTION) YY - 154 EFFECT OF POLYMER SOLUTION PROPERTIES (VISCOSITY, CONDUCTIVITY, SURFACE TENSION) ON ELECTROSPUN FIBERS - 154 3.2.4 3.2.5 3.2.6 EFFECT OF APPLIED VOLTAGE AND FEED RATE - 155 EFFECT OF DISTANCE OF NOZZLE TO COLLECTOR YY - 155 EFFECT OF DISTANCE OF AMBIENT PARAMETERS (TEMPERATURE, HUMIDITY IN THE CHAMBER) YY - 156 3.2.7 3.2.8 3.2.9 3.2.10 3.3 3.3.1 3.3.2 3.4 3.4.1 3.5 3.5.1 3.5.2 3.5.3 3.5.4 3.5.5 3.5.6 3.5.7 3.6 3.6.1 3.6.2 3.6.3 3.6.4 3.7 3.7.1 3.7.2 3.7.3 3.8 3.8.1 EFFECT OF MOTION OF THE NOZZLE AND COLLECTOR ROTATION ---- 156 EFFECT OF NOZZLE GAUGE - 156 CHALLENGES IN ELECTROSPINNING ---- 157 ELECTROSPINNING MODIFICATIONS - 157 3D BIOPRINTING ---- 163 BASICS OF 3D BIOPRINTING ---- 163 BIOINK ---- 165 3D METAL AND CERAMIC PRINTING - 171 SELECTIVE LASER SINTERING - 171 COATING METHODS ---- 172 DIP COATING ---- 172 SPIN COATING ---- 173 SPRAY COATING (COLD SPRAYING) - 174 ELECTROSPRAYING ---- 174 ELECTROPOLYMERIZATION COATING - 175 UV-LIGHT-ASSISTED COATING - 175 COATING METHOD CHALLENGES ---- 176 HYDROGEL PREPARATIONS - 177 PHYSICAL CROSS-LINKING ---- 177 CHEMICAL CROSS-LINKING (POLYMER GRAFTING) - 179 UNIQUE HYDROGEL ITERATIONS USED IN BIOMEDICINE ---- 180 HYDROGEL PREPARATION CHALLENGES - 181 INORGANIC AND ORGANIC NANOPARTICLES PREPARATIONS - 182 ORGANIC NANOPARTICLES ---- 182 INORGANIC NANOPARTICLES - 185 CHALLENGES IN NANOPARTICLES SYNTHESIS - 190 BIOCERAMIC SYNTHESIS METHODS ---- 191 WET CHEMICAL PRECIPITATION SYNTHESIS OF BIOCERAMICS (HYDROXYAPATITE) - 191 3.8.2 SOL-GEL METHOD IN THE PREPARATION OF BULK POROUS BIOCERAMIC ---- 192 CONTENTS - XV 3.8.3 3.8.4 3.8.5 3.8.6 3.9 3.9.1 3.9.2 3.9.3 3.9.4 3.9.5 3.9.6 3.9.7 3.10 HYDROTHERMAL METHOD FOR CREATING CALCIUM OXIDE ---- 192 SOLID-STATE REACTIONS IN THE PREPARATION OF SYNTHETIC APATITE ---- 193 MELTING-QUENCHING METHOD FOR BIOGLASS PREPARATION ---- 193 CHALLENGES IN BIOCERAMIC SYNTHESIS AND MANUFACTURING ---- 194 FABRICATION METHODS OF BIOMEDICAL-GRADE ALLOYS - 194 THERMOMECHANICAL PROCESS (TMP) ---- 195 HOT ISO-STATIC PRESSING (HIP) ---- 195 POWDER METALLURGY (SINTERING) ---- 196 SUPERPLASTIC DEFORMATION AND ISOTHERMAL FORGING - 196 ELASTIC METAL ALLOY MANUFACTURING (NITINOT) ---- 197 POST-PROCESSING OF METALLIC ALLOYS TO BE USED IN BIOMEDICINE - 198 CHALLENGES IN METAL FABRICATION FOR BIOMEDICAL APPLICATIONS - 199 CONCLUSIONS - 199 REFERENCES ---- 200 CHAPTER 4 BIOMATERIALS AND THE HUMAN IMMUNE SYSTEM - 223 4.1 4.1.1 4.1.2 4.1.3 4.1.4 THE HUMAN IMMUNE RESPONSE TOWARD BIOMATERIALS - 223 THE BASICS OF THE HUMAN IMMUNE SYSTEM - 223 CLASSES OF IMMUNE CELLS ---- 224 COMMUNICATION BETWEEN IMMUNE CELLS ---- 228 IMMUNOGLOBULINS AND THEIR ROLE TO IMMUNE RESPONSE (ANTIBODY IMMUNE RESPONSE) - 229 4.1.5 THE MAJOR HISTOCOMPATIBILITY COMPLEX AND ACTIVATED COMPLEMENT PROTEINS (PROTEINS ROLE IN IMMUNITY) ---- 230 4.2 4.2.1 4.2.2 4.3 THE BODY ' S GENERAL RESPONSE TOWARD BIOMATERIALS - 232 FOREIGN BODY RESPONSE ---- 232 INFLAMMATION AND WOUND HEALING PROCESS - 234 THE BODY ' S RESPONSE TOWARD DIFFERENT CLASSES OF BIOMATERIALS AND BIOMEDICAL DEVICES - 235 4.3.1 4.3.2 4.3.3 4.4 4.5 4.5.1 METALLIC MATERIALS AND THE IMMUNE SYSTEM - 235 CERAMIC MATERIALS AND THE IMMUNE SYSTEM - 239 POLYMERIC MATERIALS AND THE IMMUNE SYSTEM ---- 239 IMMUNE RESPONSES TO NANOMATERIALS - 242 IMMUNE MODULATION TOOLS IN BIOMATERIALS - 244 PHYSICAL MODIFICATIONS (SURFACE TOPOGRAPHY AND HYDROPHILICITY) ---- 245 4.5.2 4.5.3 4.6 CHEMICAL MODIFICATIONS - 246 ACTIVE DELIVERY OF IMMUNE-MODULATORY COMPOUNDS ---- 247 CONCLUSION ---- 247 REFERENCES ---- 248 XVI - CONTENTS CHAPTER 5 BIOMATERIALS IN MEDICAL DEVICE DEVELOPMENT - 257 5.1 5.1.1 5.1.2 5.1.3 5.2 5.3 BIOMATERIALS ' ROLE IN MEDICAL DEVICE DEVELOPMENT ---- 257 CLASS 1 MEDICAL DEVICES ---- 257 CLASS II MEDICAL DEVICES ---- 258 CLASS III MEDICAL DEVICES - 259 BIOMATERIALS IN MEDICAL DEVICES (BIOSENSORS) - 259 BIOMATERIALS IN MEDICAL DEVICES (VASCULAR AND NONVASCULAR STENTS) ---- 261 5.3.1 5.3.2 5.4 5.4.1 5.4.2 5.5 VASCULAR STENTS ---- 262 NONVASCULAR STENTS - 266 BIOMATERIAL IN MEDICAL DEVICES (ARTIFICIAL HEART VALVES) ---- 270 MECHANICAL HEART VALVES - 272 TISSUE (ENGINEERED) HEART VALVES - 273 BIOMATERIAL IN MEDICAL DEVICES (BONE PROSTHESIS AND IMPLANTS) ---- 276 5.5.1 5.6 BONE PROSTHESIS (ARTIFICIAL HIP AND KNEE PROSTHESIS) - 277 BIOMATERIAL IN MEDICAL DEVICES (INTRAPERITONEAL MESH IMPLANTS) ---- 281 5.7 CONCLUSION ---- 284 REFERENCES ---- 285 CHAPTER 6 BIOMATERIALS IN CANCER TREATMENT - 297 6.1 6.2 6.2.1 CANCER AND ITS TREATMENT MODALITIES - 297 BIOMATERIALS IN CANCER CHEMOTHERAPY AND DIAGNOSTICS - 298 BIOMATERIAL DRUG DELIVERY SYSTEM FOR ENHANCING CHEMOTHERAPY EFFECTS ---- 298 6.2.2 6.2.3 6.2.4 6.2.5 6.2.6 6.3 6.4 6.4.1 6.4.2 6.4.3 6.4.4 6.4.5 6.4.6 6.5 PASSIVE TUMOR TARGETING - 302 ACTIVE TUMOR TARGETING ---- 304 THE PROTON SPONGE EFFECT - 305 NANOPARTICLE TRANSPORT ACROSS PHYSIOLOGICAL BARRIERS - 306 THERANOSTICS ---- 308 BIOMATERIALS USED IN SURGICAL INTERVENTION OF CANCER - 309 BIOMATERIALS USED IN HYPERTHERMIA TREATMENT OF CANCER - 313 MAGNETIC HYPERTHERMIA (NANOPARTICLE HEATING) - 316 MAGNETIC HYPERTHERMIA (BULK HEATING) - 318 PHOTODYNAMIC HYPERTHERMIA THERAPY - 320 METALLIC NANOPARTICLE-MEDIATED PTT - 321 CARBON-BASED NANOMATERIAL-MEDIATED PTT - 321 POLYMERIC MATERIAL-MEDIATED PTT ---- 321 BIOMATERIALS USED IN IMMUNOTHERAPY OF CANCER ---- 322 CONTENTS - XVII 6.5.1 6.5.2 6.5.3 6.6 IMPLANTABLE AND INJECTABLE BIOMATERIALS FOR IMMUNOTHERAPY ---- 322 TRANSDERMAL BIOMATERIALS FOR IMMUNOTHERAPY ---- 327 NANOPARTICLE TECHNOLOGY IN CANCER IMMUNOTHERAPY ---- 327 CONCLUSION ---- 329 REFERENCES ---- 330 CHAPTER 7 BIOMATERIALS IN DRUG DELIVERY ---- 345 7.1 7.1.1 7.1.2 7.1.3 7.1.4 7.1.5 7.1.6 7.2 7.2.1 7.2.2 7.2.3 7.2.4 PHARMACOLOGICAL CONCEPTS ---- 345 CONVENTIONAL DELIVERY METHODS FOR DRUG COMPOUNDS ---- 345 DRUG CLASSIFICATIONS - 347 DRUG-TO-DRUG INTERACTIONS ---- 349 ADVERSE AND SIDE EFFECTS OF THERAPEUTIC COMPOUNDS ---- 349 THERAPEUTIC RANGE ---- 350 PHARMACOKINETICS AND PHARMACODYNAMICS - 350 BIOMATERIALS ' ROLE IN DRUG DELIVERY ---- 351 BIOMATERIALS IN SYSTEMIC DRUG DELIVERY ---- 353 BIOMATERIALS IN ALTERNATIVE DRUG DELIVERY ---- 372 BIOMATERIALS IN GENE THERAPY AGENT DELIVERY ---- 379 BIOMATERIALS ALLOW DRUG DELIVERY CAPABILITIES IN MEDICAL DEVICES ---- 384 7.3 CONCLUSION ---- 385 REFERENCES ---- 385 CHAPTER 8 BIOMATERIALS IN TISSUE ENGINEERING - 399 8.1 8.1.1 8.1.2 8.1.3 8.1.4 8.2 8.2.1 8.2.2 8.2.3 8.3 TISSUE DISEASES AND REPAIR PROCESS ---- 399 PHYSICAL INJURIES AND ITS HEALING PROCESS ---- 400 DEGENERATIVE AND AUTOIMMUNE DISEASES - 403 PERFUSION AND ISCHEMIC ACCIDENTS ---- 407 CONGENITAL DEFECTS - 410 TISSUE ENGINEERING METHODS AND APPLICATIONS - 410 CONVENTIONAL TISSUE ENGINEERING - 412 STEM CELL BIOMATERIAL-BASED TISSUE ENGINEERING - 426 BIOMATERIALS IN CLOSED-LOOP TISSUE ENGINEERING METHODS - 432 CONCLUSIONS ---- 433 REFERENCES ---- 433 CONCLUDING REMARKS - 447 INDEX ---- 449
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id	DE-604.BV048381991
illustrated	Illustrated
index_date	2024-07-03T20:19:08Z
indexdate	2024-07-10T09:36:34Z
institution	BVB
institution_GND	(DE-588)10095502-2
isbn	9783110655353 3110655357
language	English
oai_aleph_id	oai:aleph.bib-bvb.de:BVB01-033760818
oclc_num	1306328913
open_access_boolean
owner	DE-83 DE-384 DE-578 DE-573 DE-703
owner_facet	DE-83 DE-384 DE-578 DE-573 DE-703
physical	XVII, 458 Seiten Illustrationen 24 cm x 17 cm
publishDate	2022
publishDateSearch	2022
publishDateSort	2022
publisher	De Gruyter
record_format	marc
series2	De Gruyter graduate
spelling	Aguilar, Ludwig Erik Verfasser (DE-588)1271061082 aut Biomaterial science anatomy and physiology aspects Ludwig Erik Aguilar Berlin ; Boston De Gruyter [2022] © 2022 XVII, 458 Seiten Illustrationen 24 cm x 17 cm txt rdacontent n rdamedia nc rdacarrier De Gruyter graduate Biomaterial (DE-588)4267769-5 gnd rswk-swf Biomaterialien Anatomie Physiologie TB: Textbook Biomaterial (DE-588)4267769-5 s DE-604 Walter de Gruyter GmbH & Co. KG (DE-588)10095502-2 pbl Erscheint auch als Online-Ausgabe, EPUB 978-3-11-065568-1 Erscheint auch als Online-Ausgabe, PDF 978-3-11-065537-7 X:MVB https://www.degruyter.com/isbn/9783110655353 DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=033760818&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis 1\p vlb 20220323 DE-101 https://d-nb.info/provenance/plan#vlb
spellingShingle	Aguilar, Ludwig Erik Biomaterial science anatomy and physiology aspects Biomaterial (DE-588)4267769-5 gnd
subject_GND	(DE-588)4267769-5
title	Biomaterial science anatomy and physiology aspects
title_auth	Biomaterial science anatomy and physiology aspects
title_exact_search	Biomaterial science anatomy and physiology aspects
title_exact_search_txtP	Biomaterial science anatomy and physiology aspects
title_full	Biomaterial science anatomy and physiology aspects Ludwig Erik Aguilar
title_fullStr	Biomaterial science anatomy and physiology aspects Ludwig Erik Aguilar
title_full_unstemmed	Biomaterial science anatomy and physiology aspects Ludwig Erik Aguilar
title_short	Biomaterial science
title_sort	biomaterial science anatomy and physiology aspects
title_sub	anatomy and physiology aspects
topic	Biomaterial (DE-588)4267769-5 gnd
topic_facet	Biomaterial
url	https://www.degruyter.com/isbn/9783110655353 http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=033760818&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA
work_keys_str_mv	AT aguilarludwigerik biomaterialscienceanatomyandphysiologyaspects AT walterdegruytergmbhcokg biomaterialscienceanatomyandphysiologyaspects

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