Gartner and Hiatt's atlas and text of histology:
Gespeichert in:
| Hauptverfasser: | , |
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| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Philadelphia ; Baltimore ; New York ; London ; Buenos Aires ; Hong Kong ; Sydney ; Tokyo
Wolters Kluwer
[2023]
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| Ausgabe: | Eighth edition, international edition |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | xxix, 618 Seiten Illustrationen |
| ISBN: | 9781975192037 1975192036 |
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MARC
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| 245 | 1 | 0 | |a Gartner and Hiatt's atlas and text of histology |c Leslie P. Gartner, PhD, Lisa M. J. Lee, PhD |
| 246 | 1 | 3 | |a Atlas and text of histology |
| 246 | 1 | 3 | |a Color atlas and text of histology |
| 250 | |a Eighth edition, international edition | ||
| 264 | 1 | |a Philadelphia ; Baltimore ; New York ; London ; Buenos Aires ; Hong Kong ; Sydney ; Tokyo |b Wolters Kluwer |c [2023] | |
| 264 | 4 | |c © 2023 | |
| 300 | |a xxix, 618 Seiten |b Illustrationen | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
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| 700 | 1 | |a Lee, Lisa M. J. |e Verfasser |4 aut | |
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Datensatz im Suchindex
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| adam_text | Contents Reviewers Preface Acknowledgments CHAPTER 1 INTRODUCTION TO HISTOLOGIC TECHNIQUES Light Microscopy Terminology of Staining for Light Microscopy Common Stains Used in Histology Transmission Electron Microscopy Scanning Electron Microscopy Interpreting Microscopic Sections CHAPTER 2 CELL BIOLOGY Plasmalemma Cytoplasm Mitochondria Ribosomes Endoplasmic Reticulum Golgi Apparatus CLINICAL CONSIDERATIONS 2-1 CLINICAL CONSIDERATIONS 2-2 CLINICAL CONSIDERATIONS 2-3 CLINICAL CONSIDERATIONS 2-4 Endosomes Lysosomes Peroxisomes CLINICAL CONSIDERATIONS 2-5 Proteasomes Cytoskeleton CLINICAL CONSIDERATIONS 2-6 Inclusions Nucleus Nucleolus Chromatin and Chromosomes CLINICAL CONSIDERATIONS 2-7 CLINICAL CONSIDERATIONS 2-8 Cell Cycle Mitosis Meiosis Necrosis and Apoptosis vi vii ix 1 1 1 2 2 6 6 7 8 9 9 10 10 10 10 12 13 17 17 17 17 20 20 20 21 21 21 22 22 23 23 23 24 24 25 PLATE 2-IA Typical Cell 2-IB Typical Cell 27 28
CONTENTS 2-2A Cell Organelles and Inclusions 29 2-2B Cell Organelles and Inclusions 30 2-ЗА Cell Surface Modifications 31 2-ЗВ Cell Surface Modifications 32 2-4А Mitosis, Light and Electron Microscopy 33 2-4В Mitosis, Light and Electron Microscopy 34 2-5 Typical Cell, Electron Microscopy Chapter Review Questions 35 36 CHAPTER 3 EPITHELIUM AND GLANDS 37 Epithelial Tissue 38 Epithelial Tissue Characteristics 38 Epithelial Tissue Classification 39 Epithelial Cell Membrane Specializations 41 Glands 45 CLINICAL CONSIDERATIONS 3-1 46 CLINICAL CONSIDERATIONS 3-2 46 CLINICAL CONSIDERATIONS 3-3 47 CLINICAL CONSIDERATIONS 3-4 47 PLATE 3-ІА Simple Epithelia and Pseudostratified Epithelium 49 З-IB Simple Epithelia and Pseudostratified Epithelium 50 3-2 Stratified Epithelium and Transitional Epithelium 51 З-ЗА Epithelial Junctions, Electron Microscopy 52 З-ЗВ Epithelial Junctions, Electron Microscopy 53 3-4A Glands 54 3-4B Glands 55 3-4C Glands 56 3-4D Glands 57 Selected Review of 11istologie Images 58 Review Plate 3-1A 58 Review Plate 3-1В 59 Review Plate 3-1C 60 Summary of Histologic Organization 61 I. Epithelium 61 A. Tfpes 61 B. General Characteristics 61 II. Glands 61 A. Exocrine Glands 61 B. Endocrine Glands 61 Chapter Review Questions CHAPTER 4 CONNECTIVE TISSUE Extracellular Matrix Fibers CLINICAL CONSIDERATIONS 4 1 62 63 64 64 66 xi
xii CONTENTS CLINICAL CONSIDERATIONS 4 2 67 CLINICAL CONSIDERATIONS 4-3 67 Ground Substance 67 CLINICAL CONSIDERATIONS 4-4 68 69 CLINICAL CONSIDERATIONS 4-5 71 Connective Tissue Types 71 Cells Mesenchymal and Mucous Connective Tissues 72 Loose (Areolar) Connective Tissue 73 Dense Irregular Connective Tissue 73 Dense Regular Connective Tissue 74 Reticular Connective Tissue 74 Elastic Connective Tissue 75 Adipose Tissue CLINICAL CONSIDERATIONS 4-6 75 76 CLINICAL CONSIDERATIONS 4-7 76 PLATE 4-1 Fibroblasts and Collagen, Transmission Electron Microscopy 77 4-2 Mast Cell, Transmission Electron Microscopy 78 4-3 Mast Cell Degranulation, Electron Microscopy 79 4-4 Developing Fat Cell, Transmission Electron Microscopy 80 4-5 Connective Tissues 81 4-6 Connective Tissues 82 4-7 Connective Tissues and Cells 83 Selected Review of Histologic Images Review Plate 4-IA 84 84 Review Plate 4-IB 85 Summary of Histologic Organization 86 I. Embryonic Connective Tissue 86 A. Mesenchymal Connective Tissue (Mesenchyme) 86 B. Mucous Connective Tissue 86 II. Connective Tissue Types 86 A. Loose (Areolar) Connective Tissue 86 B. Reticular Connective Tissue 86 C. Adipose Tissue 86 III. Extracellular Matrix 86 A. Dense Irregular Connective Tissue 87 B. Dense Regular Connective Tissue 87 C. Elastic Connective Tissue Chapter Review Questions CHAPTER 5 CARTILAGE AND BONE Cartilage 87 88 89 90 Cartilage Extracellular Matrix Cartilage Cellular Component 90 90 Perichondrium 91
CONTENTS Cartilage Growth 91 Cartilage Types 92 Bone 93 CLINICAL CONSIDERATIONS 5-1 94 CLINICAL CONSIDERATIONS 5 2 94 Bone Extracellular Matrix 94 Periosteum and Endosteum 96 Bone Cells 97 Osteogenesis 98 CLINICAL CONSIDERATIONS 5-3 101 CLINICAL CONSIDERATIONS 5-4 101 CLINICAL CONSIDERATIONS 5-5 103 Hormonal Influences on Bone 103 PLATE 5-IA Cartilage 104 5-IB Cartilage 105 5-2A Bone 106 5-2B Bone 107 5-2C Bone 108 5-3B Cells of the Bone 109 5-3B Cells of the Bone 110 5-3B Cells of the Bone 111 Selected Review of I listologic Images 112 Review Plate 5-IA 112 Review Plate 5-IB 113 Review Plate 5-2 114 Summary of Histologic Organization 115 I. Cartilage 115 A. Embryonic Cartilage 115 B. Hyaline Cartilage 115 C. Elastic Cartilage 115 D. Fibrocartilage 115 II. Bone 115 A. Compact Bone 115 B. Cancellous (Spongy, Medullary) Bone 116 C. Osteogenesis 116 Chapter Review Questions CHAPTER 6 BLOOD AND HEMOPOIESIS Blood 117 118 119 Formed Elements of Blood 119 CLINICAL CONSIDERATIONS 6-1 120 CLINICAL CONSIDERATIONS 6-2 120 CLINICAL CONSIDERATIONS 6-3 122 CLINICAL CONSIDERATIONS 6-4 123 CLINICAL CONSIDERATIONS 6-5 123 xiii
CONTENTS CLINICAL CONSIDERATIONS 6-6 124 CLINICAL CONSIDERATIONS 6-7 124 Plasma and Serum 125 Hemopoiesis 125 Erythrocytic Series 126 Granulocytic Series 126 Lymphoid Series 126 Hemopoietic Growth Factors 127 CLINICAL CONSIDERATIONS 6-8 127 PLATE 6-1A Circulating Blood 129 6-IB Circulating Blood 130 6-2 Circulating Blood (Drawing) 131 6-3 Blood and Hemopoiesis 132 6-4A Bone Marrow 133 6-4B Blood Smear and Bone Marrow Smear 134 6-5 Erythropoiesis 135 6-6 Granulocytopoiesis 136 Selected Review of 1 listologic Images 137 Review Plate 6-IA 137 Review Plate 6-IB 138 Review Plate 6-2A 139 Review Plate 6-2B 140 Summary of Histologic Organization 141 I. Circulating Blood 141 A. Erythrocytes (RBC) 141 B. Agranulocytes 141 C. Granulocytes 141 D. Platelets 141 E. Erythrocytic Series 141 F. Granulocytic Series 142 Chapter Review Questions 143 CHAPTER? MUSCLE 144 Skeletal Muscle 146 Myofilaments 146 CLINICAL CONSIDERATIONS 7-1 Sliding Filament Model of Skeletal Muscle Contraction 148 148 CLINICAL CONSIDERATIONS 7 2 151 CLINICAL CONSIDERATIONS 7-3 152 Skeletal Muscle Motor Innervation 152 Cardiac Muscle 153 CLINICAL CONSIDERATIONS 7-4 155 Morphologic Components of Cardiac Muscle Cells 155 CLINICAL CONSIDERATIONS 7-5 156 Smooth Muscle 156 Smooth Muscle Contraction 156
CONTENTS 1 1 АГЕ 7-lA Skeletal Muscle 158 7֊IB Skeletal Muscle 159 Skeletal Muscle, Electron Microscopy 160 7-3A Myoneural Junction, Light Microscopy 161 7-3B Myoneural Junction, Electron Microscopy 162 Muscle Spindle, Light and Electron Microscopy 163 7-5A Smooth Muscle 164 7-5B Smooth Muscle 165 7-6 7-7A Smooth Muscle, Electron Microscopy Cardiac Muscle 166 167 7-7B Cardiac Muscle 168 Cardiac Muscle, Electron Microscopy 169 Selected Review of 1 [istologie Images 170 Review Plate 7-lA 170 Review Plate 7-IB 171 Review Plate 7-2A 172 Review Plate 7-2B 173 Review Plate 7-3A 174 Review Plate 7-3 В 175 Summary of Histologic Organization 176 I. Skeletal Muscle 176 7-2 7-4 7-8 A. Longitudinal Section 176 B. Transverse Section 176 II. Cardiac Muscle A. Longitudinal Section B. Transverse Section III. Smooth Muscle 176 176 176 176 A. Longitudinal Section B. Transverse Section 176 176 Chapter Review Questions 177 CHAPTERS NERVOUS TISSUE Nervous System Neurons CLINICAL CONSIDERATIONS 8-1 178 178 179 183 CLINICAL CONSIDERATIONS 8-2 183 CLINICAL CONSIDERATIONS 8-3 184 CLINICAL CONSIDERATIONS 8-4 184 Histologic Basis for Neuroanatomy 184 185 CLINICAL CONSIDERATIONS 8 5 Membrane Resting Potential CLINICAL CONSIDERATIONS 8 6 186 187 CLINICAL CONSIDERATIONS 8-7 187 Action Potential 188 Neuromuscular (Myoneural) Junction 190 Neurotransmitters and Neuromodulators 190 XV
xvi CONTENTS CLINICAL CONSIDERATIONS 8-8 190 192 Central Nervous System 193 Blood-Brain Barrier PLATE 8-1 8-2 Cerebrum and Neuroglial Cells 8-3 Sympathetic Ganglia and Sensory Ganglia 194 195 8-4 Peripheral Nerve 196 8-5 Peripheral Nerve, Electron Microscopy 197 8-6 Neuron Cell Body, Electron Microscopy 198 Selected Review of Histologic Images 199 Review Plate 8-1 199 Review Plate 8-2A 200 Review Plate 8-2B 201 Summary of Histologic Organization 202 I. Neurons 202 A. Cell Body/Soma/Perikaryon 202 B. Dendrite 202 C. Axon 202 II. Neuroglia 202 A. CNS 202 B. PNS 202 III. Spinal Cord 202 A. White Matter (Outer Layer) 202 B. Gray Matter (Core) 202 IV. Brain 202 A. Gray Matter (Outer Layer) 202 B. White Matter (Core) 202 C. Ventricles 203 D. Meninges 203 V. Dorsal Root Ganglia 203 VI. Peripheral Nerve 203 A. Longitudinal Section B. Transverse Section 203 203 Chapter Review Questions 204 CHAPTER 9 CIRCULATORY SYSTEM 205 206 Cardiovascular System Histologic Layers of Blood Vessels Heart 206 CLINICAL CONSIDERATIONS 9-1 206 208 Arteries Elastic Arteries 208 208 Muscular Arteries CLINICAL CONSIDERATIONS 9-2 CLINICAL CONSIDERATIONS 9-3 209 210 210
CONTENTS CLINICAL CONSIDERATIONS 9-4 Arterioles CLINICAL CONSIDERATIONS 9-5 2Ю 210 2H CLINICAL CONSIDERATION 9-6 211 214 Veins 214 Lymph Vascular System 215 PLATE 9-IA Elastic Artery 216 9-1В Elastic Artery 217 9-2A 9-2B Muscular Artery, Vein Muscular Artery and Large Vein 218 219 Capillaries 9-3A Arterioles and Venules 220 9-3B 9-4A Capillaries and Lymph Vessels Heart: Endocardium and Myocardium 221 222 9-4B Heart Valve 223 Capillary, Transmission Electron Microscopy 224 9-5 9-6 Freeze Etch, Fenestrated Capillary, Electron Microscopy 225 Selected Review of 1 Fisiologie Images Review Plate 9-IA 226 226 Review Plate 9-IB 227 Review Plate 9-2 228 Summary of Histologic Organization I. Elastic Artery (Conducting Artery) 229 229 A. Tunica Intima 229 B. Tunica Media 229 C. Tunica Adventitia II. Muscular Artery (Distributing Artery) 229 229 A. Tunica Intima 229 B. Tunica Media 229 C. Tunica Adventitia 229 III. Arterioles A. Tunica Intima 229 229 B. Tunica Media 229 C. Tunica Adventitia 229 IV. Capillaries 229 V. Venules A. Tunica Intima 229 229 B. Tunica Media 230 C. Tirnica Adventitia 230 VI. Medium-Sized Veins A. Tunica Intima 230 230 B. Tunica Media 230 C. Tunica Adventitia 230 VIL Large Veins A. Tunica Intima 230 230 xvii
xviii CONTENTS В. Tunica Media 230 C. Tunica Adventitia 230 VIII. Heart 230 IX. Lymphatic Vessels 230 Chapter Review Questions 231 CHAPTER 10 LYMPHOID (IMMUNE) SYSTEM General Plan of the Immune System CLINICAL CONSIDERATIONS 10-1 Antibodies CLINICAL CONSIDERATIONS 10-2 Immune Response Cells of the Adaptive and Innate Immune Systems 232 233 235 236 236 CLINICAL CONSIDERATIONS 10 3 237 237 237 CLINICAL CONSIDERATIONS 10 4 240 CLINICAL CONSIDERATIONS 10-5 240 Diffuse Lymphoid Tissue 241 Lymphoid Follicles (Lymphoid Nodules) 241 Lymphoid Organs CLINICAL CONSIDERATIONS 10-6 242 243 CLINICAL CONSIDERATIONS 10 7 244 CLINICAL CONSIDERATIONS 10-8 244 CLINICAL CONSIDERATIONS 10-9 246 CLINICAL CONSIDERATIONS 10-10 248 CLINICAL CONSIDERATIONS 10-11 248 PIATE 10-1A Lymphatic Infiltration 249 10-1B Lymphoid Nodules 250 10-2А Lymph Node 251 10-2B Lymph Node 252 10-3A Lymph Node 253 10-3B Tonsils 254 Lymph Node, Electron Microscopy 255 10-5A Thymus 256 10-4 10-5В Thymus 257 10-6A Spleen 258 10-6B Spleen 259 Selected Review of Histologic Images 260 Review Plate 10-1A Review Plate 10-IB 260 261 Review Plate 10-2A 262 Review Plate 10-2B 263 Summary of Histologic Organization 264 I. Lymph Node 264 A. Capsule B. Cortex 264 264
CONTENTS C. Paracortex 264 D. Medulla 264 E. Reticular Fibers 264 IJ. Tonsils A. Palatine Tonsils 264 B. Pharyngeal Tonsils 264 C. Lingual Tonsils 264 III. Spleen 265 A. Capsule 265 B. White Pulp 265 C. Marginal Zone 265 D. Red Pulp 265 E. Reticular Fibers 265 IV. Thymus CHAPTER 11 264 265 A. Capsule 265 B. Cortex 265 C. Medulla 265 D. Involution 265 E. Reticular Fibers and Sinusoids 265 Chapter Review Questions 266 ENDOCRINE SYSTEM 267 Pituitary Gland 268 Vascular Supply of the Pituitary Gland 270 Pars Anterior (Pars Distalis) 271 Pars Intermedia 272 Pars Tuberalis 272 Pars Nervosa and Infundibular Stalk 272 Thyroid Gland 274 Thyroid Hormone 274 Synthesis of Thyroid Hormone CLINICAL CONSIDERATIONS 11-1 Release of Thyroid Hormone 274 275 275 Parathyroid Glands 276 CLINICAL CONSIDERATIONS 11-2 279 CLINICAL CONSIDERATIONS 11-3 279 Suprarenal Glands 279 Cortex 279 Medulla 280 Pineal Gland 281 CLINICAL CONSIDERATIONS 114 283 Mechanism of Hormonal Action 284 Nonsteroid-Based Hormones and Amino Acid Derivatives 284 Steroid-Based Hormones 285
XX CONTENTS Selected Review of Histologic Images 286 Review Plate 11-1A 286 Review Plate 11-1B 287 Review Plate 11 ֊2A 288 Review Plate 11-2B 289 Review Plate 11-ЗА 290 Review Plate 11-3B 291 Review Plate 11-4A 292 Review Plate 11-4B 293 Review Plate 11-5A 294 Review Plate 11-5B 295 Summary of Histologic Organization 296 I. Pituitary Gland A. Adenohypophysis (Anterior Pituitary) 296 B. Neurohypophysis (Posterior Pituitary) 296 II. Thyroid Gland 296 296 A. Capsule B. Parenchymal Cells 296 296 C. Connective Tissue 29 c III. Parathyroid Gland 2^6 A. Capsule B. Parenchymal Cells 296 C. Connective Tissue 297 IV. Suprarenal (Adrenal) Gland 297 297 A. Cortex 297 B. Medulla 297 V. Pineal Gland 297 A. Capsule 297 B. Parenchymal Cells 297 C. Brain Sand (Corpora Arenacea) 297 Chapter Review Questions CHAPTER 12 INTEGUMENT Skin 298 299 299 CLINICAL CONSIDERATIONS 12-1 300 304 CLINICAL CONSIDERATIONS 12-2 307 Epidermis Dermis 307 CLINICAL CONSIDERATIONS 12-3 308 Derivatives of Skin Selected Review of 11istologie Images 308 Review Plate 12-IA Review Plate 12-IB 315 315 316
CONTENTS Review Plate 12-1C 317 Review Plate 12-1C 318 Review Plate 12-1D 319 Summary of Histologie Organization 320 320 1. Skin A. Epidermis 320 B. Dermis 320 II. Appendages 320 A. Hair 320 В. Sebaceous Glands 320 C. Arrector Pili Muscle 321 D. Sweat Glands 321 E. Nail 321 Chapter Review Questions CHAPTER 13 RESPIRATORY SYSTEM Conducting Portion of the Respiratory System 322 323 324 Respiratory Epithelium Extrapulmonary Region 324 324 Intrapulmonary Region 329 Respiratory Portion of the Respiratory System 330 Mechanism of Gaseous Exchange CLINICAL CONSIDERATIONS 13-2 334 335 338 CLINICAL CONSIDERATIONS 13 3 338 CLINICAL CONSIDERATION 13 4 340 Selected Review of l [istologie Images 341 Review Plate 13-1A 341 Review Plate 13-IB 342 Review Plate 13-1C 343 Summary of Histologic Organization 344 I. Conducting Portion 344 CLINICAL CONSIDERATIONS 13 1 A. Nasal Cavity 344 B. Larynx 344 C. Trachea D. Extrapulmonary Bronchi 344 344 E. Intrapulmonary Bronchi 344 E Bronchioles 344 G. Terminal Bronchioles 344 II. Respiratory Portion 344 A. Respiratory Bronchiole 344 B. Alveolar Ducts 345 C. Alveolar Sacs 345 D. Alveolus 345 Chapter Review Questions 346 xxi
xxii CONTENTS CHAPTER 14 DIGESTIVE SYSTEM 1 Oral Region: Oral Cavity 347 348 Oral Mucosa 348 Lips 348 CLINICAL CONSIDERATIONS 14-1 350 Salivary Glands 350 Palate 350 Teeth Structure of Teeth CLINICAL CONSIDERATIONS 14-2 Supporting Apparatus of the Tooth 351 351 352 352 CLINICAL CONSIDERATIONS 14-3 353 CLINICAL CONSIDERATIONS 14-4 354 Odontogenesis 354 Morphology of Odontogenesis 354 CLINICAL CONSIDERATIONS 14-5 355 CLINICAL CONSIDERATIONS 14-6 356 Tongue 357 CLINICAL CONSIDERATIONS 14-7 358 Lingual Papillae 353 Taste Buds and Taste Perception 3;դ PLATE 14-ІА Lip 360 14-lB Lip 361 14-2A Tooth 362 14-2B Pulp 363 14-3 A Periodontal Ligament 364 14-3B Gingiva 365 14-4A Tooth Development 366 14-4B Tooth Development 367 14-5 A Tongue 368 14-5B Tongue 369 14-6A Tongue 370 14-6B Palate 371 14-7A Teeth 372 14-7B Nasal Aspect of the Hard Palate 373 14-8 Scanning Electron Micrograph of Tooth Enamel 374 14-9 Scanning Electron Micrograph of Tooth Dentin 375 Selected Review of Histologic Images 376 Review Plate 14-1A 376 Review Plate 14-IB 377 Review Plate 14-2 378 Summary of Histologic Organization 379 1. Lips 379 A. External Surface 379
CONTENTS B. Transitional Zone C. Mucous Membrane D. Core of the Lip II. Teeth 379 379 379 379 A. Enamel 379 B. Dentin 379 379 C. Cementům D. Pulp 379 III. Gingiva 379 IV. Tongue A. Oral Region (Anterior Two-Thirds) 379 379 B. Pharyngeal Region (Posterior One-Third) 380 V. Palate VI. Tooth Development 380 380 Chapter Review Questions 381 CHAPTER 15 DIGESTIVE SYSTEM II Layers of the Wall of the Alimentary Canal 382 383 Mucosa 383 Submucosa Muscularis Externa 383 385 Serosa or Adventitia 385 Regions of the Alimentary Canal Esophagus CLINICAL CONSIDERATIONS 15-1 Stomach CLINICAL CONSIDERATIONS 15 2 385 385 386 387 387 Small Intestine 391 Large Intestine 392 393 Rectum, Anal Canal, and Appendix Progress of Food Through the Alimentary Canal 393 Microbiota of the Large Intestine 395 395 Digestion and Absorption Carbohydrates 395 Proteins 395 Lipids 395 Water and Ions Composition of Feces 395 CLINICAL CONSIDERATIONS 15-3 396 395 PLATI· 15-IA Esophagus 15-IB Esophagus and Esophagogastric Junction 397 15-2A Stomach 399 15-2B Stomach 400 15-3A Stomach 401 15-3B Stomach 402 398 XXÍIÍ
xxiv CONTENTS 15-4A Duodenum 403 15-4B Duodenum 404 15-5А Jejunum 15-5B Ileum 405 15-6A Colon 15-6B Appendix 15-7 Colon, Electron Microscopy 407 15-8 Colon, Scanning Electron Microscopy Selected Review of Histologie Images Review Plate 15-IA 406 408 409 410 411 411 Review Plate 15-1В 412 Review Plate 15-2A Review Plate 15-2 В 413 414 Summary of Histologie Organization 415 I. Esophagus 415 A. Mucosa 415 В. Submucosa 415 C. Muscularis Externa 415 D. Adventitia 415 II. Stomach 415 A. Mucosa 415 B. Submucosa 415 C. Muscularis Externa 415 D. Serosa 416 III. Small Intestine 416 A. Mucosa 416 B. Submucosa 416 C. Muscularis Externa 416 D. Serosa 416 IV. Large Intestine A. Colon B. Appendix C. Anal Canal Chapter Review Questions CHAPTER 16 DIGESTIVE SYSTEM III Major Salivary Glands 416 416 416 417 418 419 420 Parotid Gland Submandibular Gland 421 Sublingual Gland Tubarial Gland 421 421 422 Pancreas 422 CLINICAL CONSIDERATIONS 16-1 423 Vascular Supply of the Pancreas CLINICAL CONSIDERATIONS 16-2 423 425 Exocrine Pancreas 425 Endocrine Pancreas 425
CONTENTS Liver 425 CLINICAL CONSIDERATIONS 16 3 426 427 CLINICAL CONSIDERATIONS 16-4 CLINICAL CONSIDERATIONS 16-5 Kupffer Cells and Perisinusoidal Stellate Cells Perisinusoidal Space (Space of Disse) Hepatocytes Functions of the Liver Gallbladder 428 428 428 428 428 CLINICAL CONSIDERATIONS 16-7 430 431 432 CLINICAL CONSIDERATIONS 16-8 432 CLINICAL CONSIDERATIONS 16-9 433 CLINICAL CONSIDERATIONS 16-6 PLATI· 16-1A Salivary Glands 434 16-1B Salivary Glands 16-2A Pancreas 435 436 16-2B Pancreas 437 16-ЗА Liver 438 439 16-3B Liver 16-4A Liver 16-4B Gallbladder 16-5 Salivary Gland, Electron Microscopy 16-6 Liver, Electron Microscopy 16-7 Pancreatic Islet of Langerhans, Electron Microscopy Selected Review of 11istologie Images 440 441 442 443 444 445 Review Plate 16-IA 445 Review Plate 16-IB 446 447 Review Plate 16-2A Review Plate 16-2B Summary of Histologic Organization 449 I. Major Salivary Glands 449 448 A. Parotid Gland 449 B. Submandibular Gland 449 C. Sublingual Gland 449 IL Pancreas 449 III. Liver 449 A. Capsule 449 B. Lobules IV. Gallbladder 449 A. Epithelium 449 B. Lamina Propria 450 C. Muscularis Externa D. Serosa 450 Chapter Review Questions 451 449 450 XXV
xxvi CONTENTS CHAPTER 17 URINARY SYSTEM 452 Kidney Uriniferous Tubule 454 CLINICAL CONSIDERATIONS 17 1 459 CLINICAL CONSIDERATIONS 17-2 459 454 Concentration of Urine in the Nephron (Countercurrent Multiplier System) Function of the Vasa Recta (Countercurrent Exchange System) 461 Collecting Tubules 461 461 CLINICAL CONSIDERATIONS 17 3 462 CLINICAL CONSIDERATIONS 17-4 462 Extrarenai Excretory Passages 463 CLINICAL CONSIDERATIONS 17-5 463 CLINICAL CONSIDERATIONS 17-6 464 PIATE 17-ІА Kidney, Survey and General Morphology 17-lB Kidney Cortex and Its Vascular Supply 465 17-2A Renal Cortex 17-2B Renal Cortex 467 17-3 Glomerulus, Scanning Electron Microscopy 17-4 Renal Corpuscle, Electron Microscopy 17-5A Renal Medulla 469 17-5B Renal Medulla 17-6A Ureter 17-6B Urinary Bladder 472 466 468 470 471 473 474 Selected Review of Histologic Images 475 Review Plate 17-IA 475 Review Plate 17-IB 476 Review Plate 17-2 477 Summary of Histologic Organization 478 I. Kidney A. Capsule 478 478 B. Cortex 478 C. Medulla D. Renal Pelvis 478 II. Extrarenai Passages 478 478 A. Ureter 478 B. Bladder 478 Chapter Review Questions CHAPTER 18 FEMALE REPRODUCTIVE SYSTEM Ovary Ovarian Follicles Corpus Luteum and Corpus Albicans Genital Ducts Oviduct Uterus 479 480 481 481 485 485 485 487
CONTENTS Fertilization and Implantation 490 Placenta 491 Fetal Component 491 Maternal Component 492 Vagina 494 External Genitalia 495 CLINICAL CONSIDERATIONS 18-1 495 CLINICAL CONSIDERATIONS 18-2 496 Mammary Gland 497 CLINICAL CONSIDERATIONS 18 3 497 CLINICAL CONSIDERATIONS 18-4 501 CLINICAL CONSIDERATIONS 18 5 501 PIATE 18-1 Ovary and Corpus Luteum 502 18-2 Ovary and Oviduct 503 18-3 Oviduct, Electron Microscopy 504 18-4 Uterus 505 18-5 Uterus 506 18-6 Mammary Gland 507 Selected Review of 1 (istologie Images 508 Review Plate 18-IA 508 Review Plate 18-IB 509 Review Plate 18-2A 510 Review Plate 18-2B 511 Summary of Histologic Organization 512 I. Ovary 512 A. Cortex 512 B. Medulla 512 C. Corpus Luteum 512 D. Corpus Albicans 512 II. Genital Ducts 512 A. Oviduct 512 B. Uterus 512 C. Placenta 513 D. Vagina 513 E. Mammary Glands 513 Chapter Review Questions CHAPTER 19 MALE REPRODUCTIVE SYSTEM 514 515 Testes 516 Seminiferous Tubules 516 CLINICAL CONSIDERATIONS 19-1 518 CLINICAL CONSIDERATIONS 19-2 518 CLINICAL CONSIDERATIONS 19-3 520 Genital Ducts 520 CLINICAL CONSIDERATIONS 19-4 522 xxvii
xxviii CONTENTS CLINICAL CONSIDERATIONS 19-5 523 Accessory Genital Glands 523 Seminal Vesicle 523 Prostate Gland 523 Bulbourethral Glands (Cowper s Glands) 524 Urethra 524 CLINICAL CONSIDERATIONS 19-6 525 CLINICAL CONSIDERATIONS 19-7 526 CLINICAL CONSIDERATIONS 19-8 526 Penis 526 Erection 526 Ejaculation 526 PLATE 19-1A Testis 527 19-IB Testis 528 19-2A Testis 529 19-2B Epididymis 530 19-3A Epididymis and Ductus Deferens 531 19-3B Seminal Vesicle 532 19-4A Prostate 19-4B Penis and Urethra 533 19-5 Epididymis, Electron Microscopy Selected Review of Histologic Images 534 535 536 Review Plate 19-IA 536 Review Plate 19-IB 537 Review Plate 19-2A 538 Review Plate 19-2B Summary of Histologic Organization 539 I. Testes 540 540 A. Capsule B. Seminiferous Tubules 540 C. Stroma 540 II. Genital Ducts 540 A. Tubuli Recti 540 B. Rete Testis 540 C. Epididymis D. Ductus (Vas) Deferens 540 540 540 III. Accessory Glands 540 A. Seminal Vesicles 540 B. Prostate Gland 540 541 C. Bulbourethral Glands IV. Penis V. Urethra A. Epithelium B. Lamina Propria Chapter Review Questions 541 541 541 541 542
CONTENTS CHAPTER 20 SPECIAL SENSES Eye 543 Fibrous Tunic 543 544 CLINICAL CONSIDERATIONS 20 1 546 Vascular Tunic CLINICAL CONSIDERATIONS 20-2 Retinal Tunic 547 548 548 CLINICAL CONSIDERATIONS 20-3 549 CLINICAL CONSIDERATIONS 20-4 550 554 CLINICAL CONSIDERATIONS 20-5 Accessory Structures of the Eye Ear 554 554 External and Middle Ear 554 Inner Ear 554 CLINICAL CONSIDERATIONS 20-6 560 Selected Review of 11 istologie Images Review Plate 20-IA 561 561 Review Plate 20-1В 562 Review Plate 20-2A 563 564 Review Plate 20-2B Summary of Histologic Organization 565 A. Fibrous Tunic 565 565 B. Vascular Tunic 565 I. Eye C. Retinal Tunic 565 D. Lens 566 E. Lacrimal Gland 566 F. Eyelid 566 566 II. Ear A. External Ear 566 B. Middle Ear 566 C. Inner Ear 566 568 Chapter Review Questions Appendix A 569 Appendix В 588 Index 591 ХХІХ
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Contents Reviewers Preface Acknowledgments CHAPTER 1 INTRODUCTION TO HISTOLOGIC TECHNIQUES Light Microscopy Terminology of Staining for Light Microscopy Common Stains Used in Histology Transmission Electron Microscopy Scanning Electron Microscopy Interpreting Microscopic Sections CHAPTER 2 CELL BIOLOGY Plasmalemma Cytoplasm Mitochondria Ribosomes Endoplasmic Reticulum Golgi Apparatus CLINICAL CONSIDERATIONS 2-1 CLINICAL CONSIDERATIONS 2-2 CLINICAL CONSIDERATIONS 2-3 CLINICAL CONSIDERATIONS 2-4 Endosomes Lysosomes Peroxisomes CLINICAL CONSIDERATIONS 2-5 Proteasomes Cytoskeleton CLINICAL CONSIDERATIONS 2-6 Inclusions Nucleus Nucleolus Chromatin and Chromosomes CLINICAL CONSIDERATIONS 2-7 CLINICAL CONSIDERATIONS 2-8 Cell Cycle Mitosis Meiosis Necrosis and Apoptosis vi vii ix 1 1 1 2 2 6 6 7 8 9 9 10 10 10 10 12 13 17 17 17 17 20 20 20 21 21 21 22 22 23 23 23 24 24 25 PLATE 2-IA Typical Cell 2-IB Typical Cell 27 28
CONTENTS 2-2A Cell Organelles and Inclusions 29 2-2B Cell Organelles and Inclusions 30 2-ЗА Cell Surface Modifications 31 2-ЗВ Cell Surface Modifications 32 2-4А Mitosis, Light and Electron Microscopy 33 2-4В Mitosis, Light and Electron Microscopy 34 2-5 Typical Cell, Electron Microscopy Chapter Review Questions 35 36 CHAPTER 3 EPITHELIUM AND GLANDS 37 Epithelial Tissue 38 Epithelial Tissue Characteristics 38 Epithelial Tissue Classification 39 Epithelial Cell Membrane Specializations 41 Glands 45 CLINICAL CONSIDERATIONS 3-1 46 CLINICAL CONSIDERATIONS 3-2 46 CLINICAL CONSIDERATIONS 3-3 47 CLINICAL CONSIDERATIONS 3-4 47 PLATE 3-ІА Simple Epithelia and Pseudostratified Epithelium 49 З-IB Simple Epithelia and Pseudostratified Epithelium 50 3-2 Stratified Epithelium and Transitional Epithelium 51 З-ЗА Epithelial Junctions, Electron Microscopy 52 З-ЗВ Epithelial Junctions, Electron Microscopy 53 3-4A Glands 54 3-4B Glands 55 3-4C Glands 56 3-4D Glands 57 Selected Review of 11istologie Images 58 Review Plate 3-1A 58 Review Plate 3-1В 59 Review Plate 3-1C 60 Summary of Histologic Organization 61 I. Epithelium 61 A. Tfpes 61 B. General Characteristics 61 II. Glands 61 A. Exocrine Glands 61 B. Endocrine Glands 61 Chapter Review Questions CHAPTER 4 CONNECTIVE TISSUE Extracellular Matrix Fibers CLINICAL CONSIDERATIONS 4 1 62 63 64 64 66 xi
xii CONTENTS CLINICAL CONSIDERATIONS 4 2 67 CLINICAL CONSIDERATIONS 4-3 67 Ground Substance 67 CLINICAL CONSIDERATIONS 4-4 68 69 CLINICAL CONSIDERATIONS 4-5 71 Connective Tissue Types 71 Cells Mesenchymal and Mucous Connective Tissues 72 Loose (Areolar) Connective Tissue 73 Dense Irregular Connective Tissue 73 Dense Regular Connective Tissue 74 Reticular Connective Tissue 74 Elastic Connective Tissue 75 Adipose Tissue CLINICAL CONSIDERATIONS 4-6 75 76 CLINICAL CONSIDERATIONS 4-7 76 PLATE 4-1 Fibroblasts and Collagen, Transmission Electron Microscopy 77 4-2 Mast Cell, Transmission Electron Microscopy 78 4-3 Mast Cell Degranulation, Electron Microscopy 79 4-4 Developing Fat Cell, Transmission Electron Microscopy 80 4-5 Connective Tissues 81 4-6 Connective Tissues 82 4-7 Connective Tissues and Cells 83 Selected Review of Histologic Images Review Plate 4-IA 84 84 Review Plate 4-IB 85 Summary of Histologic Organization 86 I. Embryonic Connective Tissue 86 A. Mesenchymal Connective Tissue (Mesenchyme) 86 B. Mucous Connective Tissue 86 II. Connective Tissue Types 86 A. Loose (Areolar) Connective Tissue 86 B. Reticular Connective Tissue 86 C. Adipose Tissue 86 III. Extracellular Matrix 86 A. Dense Irregular Connective Tissue 87 B. Dense Regular Connective Tissue 87 C. Elastic Connective Tissue Chapter Review Questions CHAPTER 5 CARTILAGE AND BONE Cartilage 87 88 89 90 Cartilage Extracellular Matrix Cartilage Cellular Component 90 90 Perichondrium 91
CONTENTS Cartilage Growth 91 Cartilage Types 92 Bone 93 CLINICAL CONSIDERATIONS 5-1 94 CLINICAL CONSIDERATIONS 5 2 94 Bone Extracellular Matrix 94 Periosteum and Endosteum 96 Bone Cells 97 Osteogenesis 98 CLINICAL CONSIDERATIONS 5-3 101 CLINICAL CONSIDERATIONS 5-4 101 CLINICAL CONSIDERATIONS 5-5 103 Hormonal Influences on Bone 103 PLATE 5-IA Cartilage 104 5-IB Cartilage 105 5-2A Bone 106 5-2B Bone 107 5-2C Bone 108 5-3B Cells of the Bone 109 5-3B Cells of the Bone 110 5-3B Cells of the Bone 111 Selected Review of I listologic Images 112 Review Plate 5-IA 112 Review Plate 5-IB 113 Review Plate 5-2 114 Summary of Histologic Organization 115 I. Cartilage 115 A. Embryonic Cartilage 115 B. Hyaline Cartilage 115 C. Elastic Cartilage 115 D. Fibrocartilage 115 II. Bone 115 A. Compact Bone 115 B. Cancellous (Spongy, Medullary) Bone 116 C. Osteogenesis 116 Chapter Review Questions CHAPTER 6 BLOOD AND HEMOPOIESIS Blood 117 118 119 Formed Elements of Blood 119 CLINICAL CONSIDERATIONS 6-1 120 CLINICAL CONSIDERATIONS 6-2 120 CLINICAL CONSIDERATIONS 6-3 122 CLINICAL CONSIDERATIONS 6-4 123 CLINICAL CONSIDERATIONS 6-5 123 xiii
CONTENTS CLINICAL CONSIDERATIONS 6-6 124 CLINICAL CONSIDERATIONS 6-7 124 Plasma and Serum 125 Hemopoiesis 125 Erythrocytic Series 126 Granulocytic Series 126 Lymphoid Series 126 Hemopoietic Growth Factors 127 CLINICAL CONSIDERATIONS 6-8 127 PLATE 6-1A Circulating Blood 129 6-IB Circulating Blood 130 6-2 Circulating Blood (Drawing) 131 6-3 Blood and Hemopoiesis 132 6-4A Bone Marrow 133 6-4B Blood Smear and Bone Marrow Smear 134 6-5 Erythropoiesis 135 6-6 Granulocytopoiesis 136 Selected Review of 1 listologic Images 137 Review Plate 6-IA 137 Review Plate 6-IB 138 Review Plate 6-2A 139 Review Plate 6-2B 140 Summary of Histologic Organization 141 I. Circulating Blood 141 A. Erythrocytes (RBC) 141 B. Agranulocytes 141 C. Granulocytes 141 D. Platelets 141 E. Erythrocytic Series 141 F. Granulocytic Series 142 Chapter Review Questions 143 CHAPTER? MUSCLE 144 Skeletal Muscle 146 Myofilaments 146 CLINICAL CONSIDERATIONS 7-1 Sliding Filament Model of Skeletal Muscle Contraction 148 148 CLINICAL CONSIDERATIONS 7 2 151 CLINICAL CONSIDERATIONS 7-3 152 Skeletal Muscle Motor Innervation 152 Cardiac Muscle 153 CLINICAL CONSIDERATIONS 7-4 155 Morphologic Components of Cardiac Muscle Cells 155 CLINICAL CONSIDERATIONS 7-5 156 Smooth Muscle 156 Smooth Muscle Contraction 156
CONTENTS 1 1 АГЕ 7-lA Skeletal Muscle 158 7֊IB Skeletal Muscle 159 Skeletal Muscle, Electron Microscopy 160 7-3A Myoneural Junction, Light Microscopy 161 7-3B Myoneural Junction, Electron Microscopy 162 Muscle Spindle, Light and Electron Microscopy 163 7-5A Smooth Muscle 164 7-5B Smooth Muscle 165 7-6 7-7A Smooth Muscle, Electron Microscopy Cardiac Muscle 166 167 7-7B Cardiac Muscle 168 Cardiac Muscle, Electron Microscopy 169 Selected Review of 1 [istologie Images 170 Review Plate 7-lA 170 Review Plate 7-IB 171 Review Plate 7-2A 172 Review Plate 7-2B 173 Review Plate 7-3A 174 Review Plate 7-3 В 175 Summary of Histologic Organization 176 I. Skeletal Muscle 176 7-2 7-4 7-8 A. Longitudinal Section 176 B. Transverse Section 176 II. Cardiac Muscle A. Longitudinal Section B. Transverse Section III. Smooth Muscle 176 176 176 176 A. Longitudinal Section B. Transverse Section 176 176 Chapter Review Questions 177 CHAPTERS NERVOUS TISSUE Nervous System Neurons CLINICAL CONSIDERATIONS 8-1 178 178 179 183 CLINICAL CONSIDERATIONS 8-2 183 CLINICAL CONSIDERATIONS 8-3 184 CLINICAL CONSIDERATIONS 8-4 184 Histologic Basis for Neuroanatomy 184 185 CLINICAL CONSIDERATIONS 8 5 Membrane Resting Potential CLINICAL CONSIDERATIONS 8 6 186 187 CLINICAL CONSIDERATIONS 8-7 187 Action Potential 188 Neuromuscular (Myoneural) Junction 190 Neurotransmitters and Neuromodulators 190 XV
xvi CONTENTS CLINICAL CONSIDERATIONS 8-8 190 192 Central Nervous System 193 Blood-Brain Barrier PLATE 8-1 8-2 Cerebrum and Neuroglial Cells 8-3 Sympathetic Ganglia and Sensory Ganglia 194 195 8-4 Peripheral Nerve 196 8-5 Peripheral Nerve, Electron Microscopy 197 8-6 Neuron Cell Body, Electron Microscopy 198 Selected Review of Histologic Images 199 Review Plate 8-1 199 Review Plate 8-2A 200 Review Plate 8-2B 201 Summary of Histologic Organization 202 I. Neurons 202 A. Cell Body/Soma/Perikaryon 202 B. Dendrite 202 C. Axon 202 II. Neuroglia 202 A. CNS 202 B. PNS 202 III. Spinal Cord 202 A. White Matter (Outer Layer) 202 B. Gray Matter (Core) 202 IV. Brain 202 A. Gray Matter (Outer Layer) 202 B. White Matter (Core) 202 C. Ventricles 203 D. Meninges 203 V. Dorsal Root Ganglia 203 VI. Peripheral Nerve 203 A. Longitudinal Section B. Transverse Section 203 203 Chapter Review Questions 204 CHAPTER 9 CIRCULATORY SYSTEM 205 206 Cardiovascular System Histologic Layers of Blood Vessels Heart 206 CLINICAL CONSIDERATIONS 9-1 206 208 Arteries Elastic Arteries 208 208 Muscular Arteries CLINICAL CONSIDERATIONS 9-2 CLINICAL CONSIDERATIONS 9-3 209 210 210
CONTENTS CLINICAL CONSIDERATIONS 9-4 Arterioles CLINICAL CONSIDERATIONS 9-5 2Ю 210 2H CLINICAL CONSIDERATION 9-6 211 214 Veins 214 Lymph Vascular System 215 PLATE 9-IA Elastic Artery 216 9-1В Elastic Artery 217 9-2A 9-2B Muscular Artery, Vein Muscular Artery and Large Vein 218 219 Capillaries 9-3A Arterioles and Venules 220 9-3B 9-4A Capillaries and Lymph Vessels Heart: Endocardium and Myocardium 221 222 9-4B Heart Valve 223 Capillary, Transmission Electron Microscopy 224 9-5 9-6 Freeze Etch, Fenestrated Capillary, Electron Microscopy 225 Selected Review of 1 Fisiologie Images Review Plate 9-IA 226 226 Review Plate 9-IB 227 Review Plate 9-2 228 Summary of Histologic Organization I. Elastic Artery (Conducting Artery) 229 229 A. Tunica Intima 229 B. Tunica Media 229 C. Tunica Adventitia II. Muscular Artery (Distributing Artery) 229 229 A. Tunica Intima 229 B. Tunica Media 229 C. Tunica Adventitia 229 III. Arterioles A. Tunica Intima 229 229 B. Tunica Media 229 C. Tunica Adventitia 229 IV. Capillaries 229 V. Venules A. Tunica Intima 229 229 B. Tunica Media 230 C. Tirnica Adventitia 230 VI. Medium-Sized Veins A. Tunica Intima 230 230 B. Tunica Media 230 C. Tunica Adventitia 230 VIL Large Veins A. Tunica Intima 230 230 xvii
xviii CONTENTS В. Tunica Media 230 C. Tunica Adventitia 230 VIII. Heart 230 IX. Lymphatic Vessels 230 Chapter Review Questions 231 CHAPTER 10 LYMPHOID (IMMUNE) SYSTEM General Plan of the Immune System CLINICAL CONSIDERATIONS 10-1 Antibodies CLINICAL CONSIDERATIONS 10-2 Immune Response Cells of the Adaptive and Innate Immune Systems 232 233 235 236 236 CLINICAL CONSIDERATIONS 10 3 237 237 237 CLINICAL CONSIDERATIONS 10 4 240 CLINICAL CONSIDERATIONS 10-5 240 Diffuse Lymphoid Tissue 241 Lymphoid Follicles (Lymphoid Nodules) 241 Lymphoid Organs CLINICAL CONSIDERATIONS 10-6 242 243 CLINICAL CONSIDERATIONS 10 7 244 CLINICAL CONSIDERATIONS 10-8 244 CLINICAL CONSIDERATIONS 10-9 246 CLINICAL CONSIDERATIONS 10-10 248 CLINICAL CONSIDERATIONS 10-11 248 PIATE 10-1A Lymphatic Infiltration 249 10-1B Lymphoid Nodules 250 10-2А Lymph Node 251 10-2B Lymph Node 252 10-3A Lymph Node 253 10-3B Tonsils 254 Lymph Node, Electron Microscopy 255 10-5A Thymus 256 10-4 10-5В Thymus 257 10-6A Spleen 258 10-6B Spleen 259 Selected Review of Histologic Images 260 Review Plate 10-1A Review Plate 10-IB 260 261 Review Plate 10-2A 262 Review Plate 10-2B 263 Summary of Histologic Organization 264 I. Lymph Node 264 A. Capsule B. Cortex 264 264
CONTENTS C. Paracortex 264 D. Medulla 264 E. Reticular Fibers 264 IJ. Tonsils A. Palatine Tonsils 264 B. Pharyngeal Tonsils 264 C. Lingual Tonsils 264 III. Spleen 265 A. Capsule 265 B. White Pulp 265 C. Marginal Zone 265 D. Red Pulp 265 E. Reticular Fibers 265 IV. Thymus CHAPTER 11 264 265 A. Capsule 265 B. Cortex 265 C. Medulla 265 D. Involution 265 E. Reticular Fibers and Sinusoids 265 Chapter Review Questions 266 ENDOCRINE SYSTEM 267 Pituitary Gland 268 Vascular Supply of the Pituitary Gland 270 Pars Anterior (Pars Distalis) 271 Pars Intermedia 272 Pars Tuberalis 272 Pars Nervosa and Infundibular Stalk 272 Thyroid Gland 274 Thyroid Hormone 274 Synthesis of Thyroid Hormone CLINICAL CONSIDERATIONS 11-1 Release of Thyroid Hormone 274 275 275 Parathyroid Glands 276 CLINICAL CONSIDERATIONS 11-2 279 CLINICAL CONSIDERATIONS 11-3 279 Suprarenal Glands 279 Cortex 279 Medulla 280 Pineal Gland 281 CLINICAL CONSIDERATIONS 114 283 Mechanism of Hormonal Action 284 Nonsteroid-Based Hormones and Amino Acid Derivatives 284 Steroid-Based Hormones 285
XX CONTENTS Selected Review of Histologic Images 286 Review Plate 11-1A 286 Review Plate 11-1B 287 Review Plate 11 ֊2A 288 Review Plate 11-2B 289 Review Plate 11-ЗА 290 Review Plate 11-3B 291 Review Plate 11-4A 292 Review Plate 11-4B 293 Review Plate 11-5A 294 Review Plate 11-5B 295 Summary of Histologic Organization 296 I. Pituitary Gland A. Adenohypophysis (Anterior Pituitary) 296 B. Neurohypophysis (Posterior Pituitary) 296 II. Thyroid Gland 296 296 A. Capsule B. Parenchymal Cells 296 296 C. Connective Tissue 29 c III. Parathyroid Gland 2^6 A. Capsule B. Parenchymal Cells 296 C. Connective Tissue 297 IV. Suprarenal (Adrenal) Gland 297 297 A. Cortex 297 B. Medulla 297 V. Pineal Gland 297 A. Capsule 297 B. Parenchymal Cells 297 C. Brain Sand (Corpora Arenacea) 297 Chapter Review Questions CHAPTER 12 INTEGUMENT Skin 298 299 299 CLINICAL CONSIDERATIONS 12-1 300 304 CLINICAL CONSIDERATIONS 12-2 307 Epidermis Dermis 307 CLINICAL CONSIDERATIONS 12-3 308 Derivatives of Skin Selected Review of 11istologie Images 308 Review Plate 12-IA Review Plate 12-IB 315 315 316
CONTENTS Review Plate 12-1C 317 Review Plate 12-1C 318 Review Plate 12-1D 319 Summary of Histologie Organization 320 320 1. Skin A. Epidermis 320 B. Dermis 320 II. Appendages 320 A. Hair 320 В. Sebaceous Glands 320 C. Arrector Pili Muscle 321 D. Sweat Glands 321 E. Nail 321 Chapter Review Questions CHAPTER 13 RESPIRATORY SYSTEM Conducting Portion of the Respiratory System 322 323 324 Respiratory Epithelium Extrapulmonary Region 324 324 Intrapulmonary Region 329 Respiratory Portion of the Respiratory System 330 Mechanism of Gaseous Exchange CLINICAL CONSIDERATIONS 13-2 334 335 338 CLINICAL CONSIDERATIONS 13 3 338 CLINICAL CONSIDERATION 13 4 340 Selected Review of l [istologie Images 341 Review Plate 13-1A 341 Review Plate 13-IB 342 Review Plate 13-1C 343 Summary of Histologic Organization 344 I. Conducting Portion 344 CLINICAL CONSIDERATIONS 13 1 A. Nasal Cavity 344 B. Larynx 344 C. Trachea D. Extrapulmonary Bronchi 344 344 E. Intrapulmonary Bronchi 344 E Bronchioles 344 G. Terminal Bronchioles 344 II. Respiratory Portion 344 A. Respiratory Bronchiole 344 B. Alveolar Ducts 345 C. Alveolar Sacs 345 D. Alveolus 345 Chapter Review Questions 346 xxi
xxii CONTENTS CHAPTER 14 DIGESTIVE SYSTEM 1 Oral Region: Oral Cavity 347 348 Oral Mucosa 348 Lips 348 CLINICAL CONSIDERATIONS 14-1 350 Salivary Glands 350 Palate 350 Teeth Structure of Teeth CLINICAL CONSIDERATIONS 14-2 Supporting Apparatus of the Tooth 351 351 352 352 CLINICAL CONSIDERATIONS 14-3 353 CLINICAL CONSIDERATIONS 14-4 354 Odontogenesis 354 Morphology of Odontogenesis 354 CLINICAL CONSIDERATIONS 14-5 355 CLINICAL CONSIDERATIONS 14-6 356 Tongue 357 CLINICAL CONSIDERATIONS 14-7 358 Lingual Papillae 353 Taste Buds and Taste Perception 3;դ PLATE 14-ІА Lip 360 14-lB Lip 361 14-2A Tooth 362 14-2B Pulp 363 14-3 A Periodontal Ligament 364 14-3B Gingiva 365 14-4A Tooth Development 366 14-4B Tooth Development 367 14-5 A Tongue 368 14-5B Tongue 369 14-6A Tongue 370 14-6B Palate 371 14-7A Teeth 372 14-7B Nasal Aspect of the Hard Palate 373 14-8 Scanning Electron Micrograph of Tooth Enamel 374 14-9 Scanning Electron Micrograph of Tooth Dentin 375 Selected Review of Histologic Images 376 Review Plate 14-1A 376 Review Plate 14-IB 377 Review Plate 14-2 378 Summary of Histologic Organization 379 1. Lips 379 A. External Surface 379
CONTENTS B. Transitional Zone C. Mucous Membrane D. Core of the Lip II. Teeth 379 379 379 379 A. Enamel 379 B. Dentin 379 379 C. Cementům D. Pulp 379 III. Gingiva 379 IV. Tongue A. Oral Region (Anterior Two-Thirds) 379 379 B. Pharyngeal Region (Posterior One-Third) 380 V. Palate VI. Tooth Development 380 380 Chapter Review Questions 381 CHAPTER 15 DIGESTIVE SYSTEM II Layers of the Wall of the Alimentary Canal 382 383 Mucosa 383 Submucosa Muscularis Externa 383 385 Serosa or Adventitia 385 Regions of the Alimentary Canal Esophagus CLINICAL CONSIDERATIONS 15-1 Stomach CLINICAL CONSIDERATIONS 15 2 385 385 386 387 387 Small Intestine 391 Large Intestine 392 393 Rectum, Anal Canal, and Appendix Progress of Food Through the Alimentary Canal 393 Microbiota of the Large Intestine 395 395 Digestion and Absorption Carbohydrates 395 Proteins 395 Lipids 395 Water and Ions Composition of Feces 395 CLINICAL CONSIDERATIONS 15-3 396 395 PLATI· 15-IA Esophagus 15-IB Esophagus and Esophagogastric Junction 397 15-2A Stomach 399 15-2B Stomach 400 15-3A Stomach 401 15-3B Stomach 402 398 XXÍIÍ
xxiv CONTENTS 15-4A Duodenum 403 15-4B Duodenum 404 15-5А Jejunum 15-5B Ileum 405 15-6A Colon 15-6B Appendix 15-7 Colon, Electron Microscopy 407 15-8 Colon, Scanning Electron Microscopy Selected Review of Histologie Images Review Plate 15-IA 406 408 409 410 411 411 Review Plate 15-1В 412 Review Plate 15-2A Review Plate 15-2 В 413 414 Summary of Histologie Organization 415 I. Esophagus 415 A. Mucosa 415 В. Submucosa 415 C. Muscularis Externa 415 D. Adventitia 415 II. Stomach 415 A. Mucosa 415 B. Submucosa 415 C. Muscularis Externa 415 D. Serosa 416 III. Small Intestine 416 A. Mucosa 416 B. Submucosa 416 C. Muscularis Externa 416 D. Serosa 416 IV. Large Intestine A. Colon B. Appendix C. Anal Canal Chapter Review Questions CHAPTER 16 DIGESTIVE SYSTEM III Major Salivary Glands 416 416 416 417 418 419 420 Parotid Gland Submandibular Gland 421 Sublingual Gland Tubarial Gland 421 421 422 Pancreas 422 CLINICAL CONSIDERATIONS 16-1 423 Vascular Supply of the Pancreas CLINICAL CONSIDERATIONS 16-2 423 425 Exocrine Pancreas 425 Endocrine Pancreas 425
CONTENTS Liver 425 CLINICAL CONSIDERATIONS 16 3 426 427 CLINICAL CONSIDERATIONS 16-4 CLINICAL CONSIDERATIONS 16-5 Kupffer Cells and Perisinusoidal Stellate Cells Perisinusoidal Space (Space of Disse) Hepatocytes Functions of the Liver Gallbladder 428 428 428 428 428 CLINICAL CONSIDERATIONS 16-7 430 431 432 CLINICAL CONSIDERATIONS 16-8 432 CLINICAL CONSIDERATIONS 16-9 433 CLINICAL CONSIDERATIONS 16-6 PLATI· 16-1A Salivary Glands 434 16-1B Salivary Glands 16-2A Pancreas 435 436 16-2B Pancreas 437 16-ЗА Liver 438 439 16-3B Liver 16-4A Liver 16-4B Gallbladder 16-5 Salivary Gland, Electron Microscopy 16-6 Liver, Electron Microscopy 16-7 Pancreatic Islet of Langerhans, Electron Microscopy Selected Review of 11istologie Images 440 441 442 443 444 445 Review Plate 16-IA 445 Review Plate 16-IB 446 447 Review Plate 16-2A Review Plate 16-2B Summary of Histologic Organization 449 I. Major Salivary Glands 449 448 A. Parotid Gland 449 B. Submandibular Gland 449 C. Sublingual Gland 449 IL Pancreas 449 III. Liver 449 A. Capsule 449 B. Lobules IV. Gallbladder 449 A. Epithelium 449 B. Lamina Propria 450 C. Muscularis Externa D. Serosa 450 Chapter Review Questions 451 449 450 XXV
xxvi CONTENTS CHAPTER 17 URINARY SYSTEM 452 Kidney Uriniferous Tubule 454 CLINICAL CONSIDERATIONS 17 1 459 CLINICAL CONSIDERATIONS 17-2 459 454 Concentration of Urine in the Nephron (Countercurrent Multiplier System) Function of the Vasa Recta (Countercurrent Exchange System) 461 Collecting Tubules 461 461 CLINICAL CONSIDERATIONS 17 3 462 CLINICAL CONSIDERATIONS 17-4 462 Extrarenai Excretory Passages 463 CLINICAL CONSIDERATIONS 17-5 463 CLINICAL CONSIDERATIONS 17-6 464 PIATE 17-ІА Kidney, Survey and General Morphology 17-lB Kidney Cortex and Its Vascular Supply 465 17-2A Renal Cortex 17-2B Renal Cortex 467 17-3 Glomerulus, Scanning Electron Microscopy 17-4 Renal Corpuscle, Electron Microscopy 17-5A Renal Medulla 469 17-5B Renal Medulla 17-6A Ureter 17-6B Urinary Bladder 472 466 468 470 471 473 474 Selected Review of Histologic Images 475 Review Plate 17-IA 475 Review Plate 17-IB 476 Review Plate 17-2 477 Summary of Histologic Organization 478 I. Kidney A. Capsule 478 478 B. Cortex 478 C. Medulla D. Renal Pelvis 478 II. Extrarenai Passages 478 478 A. Ureter 478 B. Bladder 478 Chapter Review Questions CHAPTER 18 FEMALE REPRODUCTIVE SYSTEM Ovary Ovarian Follicles Corpus Luteum and Corpus Albicans Genital Ducts Oviduct Uterus 479 480 481 481 485 485 485 487
CONTENTS Fertilization and Implantation 490 Placenta 491 Fetal Component 491 Maternal Component 492 Vagina 494 External Genitalia 495 CLINICAL CONSIDERATIONS 18-1 495 CLINICAL CONSIDERATIONS 18-2 496 Mammary Gland 497 CLINICAL CONSIDERATIONS 18 3 497 CLINICAL CONSIDERATIONS 18-4 501 CLINICAL CONSIDERATIONS 18 5 501 PIATE 18-1 Ovary and Corpus Luteum 502 18-2 Ovary and Oviduct 503 18-3 Oviduct, Electron Microscopy 504 18-4 Uterus 505 18-5 Uterus 506 18-6 Mammary Gland 507 Selected Review of 1 (istologie Images 508 Review Plate 18-IA 508 Review Plate 18-IB 509 Review Plate 18-2A 510 Review Plate 18-2B 511 Summary of Histologic Organization 512 I. Ovary 512 A. Cortex 512 B. Medulla 512 C. Corpus Luteum 512 D. Corpus Albicans 512 II. Genital Ducts 512 A. Oviduct 512 B. Uterus 512 C. Placenta 513 D. Vagina 513 E. Mammary Glands 513 Chapter Review Questions CHAPTER 19 MALE REPRODUCTIVE SYSTEM 514 515 Testes 516 Seminiferous Tubules 516 CLINICAL CONSIDERATIONS 19-1 518 CLINICAL CONSIDERATIONS 19-2 518 CLINICAL CONSIDERATIONS 19-3 520 Genital Ducts 520 CLINICAL CONSIDERATIONS 19-4 522 xxvii
xxviii CONTENTS CLINICAL CONSIDERATIONS 19-5 523 Accessory Genital Glands 523 Seminal Vesicle 523 Prostate Gland 523 Bulbourethral Glands (Cowper's Glands) 524 Urethra 524 CLINICAL CONSIDERATIONS 19-6 525 CLINICAL CONSIDERATIONS 19-7 526 CLINICAL CONSIDERATIONS 19-8 526 Penis 526 Erection 526 Ejaculation 526 PLATE 19-1A Testis 527 19-IB Testis 528 19-2A Testis 529 19-2B Epididymis 530 19-3A Epididymis and Ductus Deferens 531 19-3B Seminal Vesicle 532 19-4A Prostate 19-4B Penis and Urethra 533 19-5 Epididymis, Electron Microscopy Selected Review of Histologic Images 534 535 536 Review Plate 19-IA 536 Review Plate 19-IB 537 Review Plate 19-2A 538 Review Plate 19-2B Summary of Histologic Organization 539 I. Testes 540 540 A. Capsule B. Seminiferous Tubules 540 C. Stroma 540 II. Genital Ducts 540 A. Tubuli Recti 540 B. Rete Testis 540 C. Epididymis D. Ductus (Vas) Deferens 540 540 540 III. Accessory Glands 540 A. Seminal Vesicles 540 B. Prostate Gland 540 541 C. Bulbourethral Glands IV. Penis V. Urethra A. Epithelium B. Lamina Propria Chapter Review Questions 541 541 541 541 542
CONTENTS CHAPTER 20 SPECIAL SENSES Eye 543 Fibrous Tunic 543 544 CLINICAL CONSIDERATIONS 20 1 546 Vascular Tunic CLINICAL CONSIDERATIONS 20-2 Retinal Tunic 547 548 548 CLINICAL CONSIDERATIONS 20-3 549 CLINICAL CONSIDERATIONS 20-4 550 554 CLINICAL CONSIDERATIONS 20-5 Accessory Structures of the Eye Ear 554 554 External and Middle Ear 554 Inner Ear 554 CLINICAL CONSIDERATIONS 20-6 560 Selected Review of 11 istologie Images Review Plate 20-IA 561 561 Review Plate 20-1В 562 Review Plate 20-2A 563 564 Review Plate 20-2B Summary of Histologic Organization 565 A. Fibrous Tunic 565 565 B. Vascular Tunic 565 I. Eye C. Retinal Tunic 565 D. Lens 566 E. Lacrimal Gland 566 F. Eyelid 566 566 II. Ear A. External Ear 566 B. Middle Ear 566 C. Inner Ear 566 568 Chapter Review Questions Appendix A 569 Appendix В 588 Index 591 ХХІХ |
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| author | Gartner, Leslie P. 1943- Lee, Lisa M. J. |
| author_GND | (DE-588)172092663 |
| author_facet | Gartner, Leslie P. 1943- Lee, Lisa M. J. |
| author_role | aut aut |
| author_sort | Gartner, Leslie P. 1943- |
| author_variant | l p g lp lpg l m j l lmj lmjl |
| building | Verbundindex |
| bvnumber | BV048203593 |
| callnumber-first | Q - Science |
| callnumber-label | QM557 |
| callnumber-raw | QM557 |
| callnumber-search | QM557 |
| callnumber-sort | QM 3557 |
| callnumber-subject | QM - Human Anatomy |
| classification_rvk | WW 1460 |
| ctrlnum | (OCoLC)1334031423 (DE-599)GBV875933726 |
| dewey-full | 611/.0180222 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 611 - Human anatomy, cytology, histology |
| dewey-raw | 611/.0180222 |
| dewey-search | 611/.0180222 |
| dewey-sort | 3611 6180222 |
| dewey-tens | 610 - Medicine and health |
| discipline | Biologie Medizin |
| discipline_str_mv | Biologie Medizin |
| edition | Eighth edition, international edition |
| format | Book |
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| id | DE-604.BV048203593 |
| illustrated | Illustrated |
| index_date | 2024-07-03T19:47:19Z |
| indexdate | 2024-07-10T09:31:54Z |
| institution | BVB |
| isbn | 9781975192037 1975192036 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-033584537 |
| oclc_num | 1334031423 |
| open_access_boolean | |
| owner | DE-355 DE-BY-UBR DE-578 |
| owner_facet | DE-355 DE-BY-UBR DE-578 |
| physical | xxix, 618 Seiten Illustrationen |
| publishDate | 2023 |
| publishDateSearch | 2023 |
| publishDateSort | 2023 |
| publisher | Wolters Kluwer |
| record_format | marc |
| spelling | Gartner, Leslie P. 1943- Verfasser (DE-588)172092663 aut Gartner and Hiatt's atlas and text of histology Leslie P. Gartner, PhD, Lisa M. J. Lee, PhD Atlas and text of histology Color atlas and text of histology Eighth edition, international edition Philadelphia ; Baltimore ; New York ; London ; Buenos Aires ; Hong Kong ; Sydney ; Tokyo Wolters Kluwer [2023] © 2023 xxix, 618 Seiten Illustrationen txt rdacontent n rdamedia nc rdacarrier Atlas (DE-588)4143303-8 gnd rswk-swf Histologie (DE-588)4025092-1 gnd rswk-swf Histologie (DE-588)4025092-1 s Atlas (DE-588)4143303-8 s DE-604 Lee, Lisa M. J. Verfasser aut Digitalisierung UB Regensburg - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=033584537&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Gartner, Leslie P. 1943- Lee, Lisa M. J. Gartner and Hiatt's atlas and text of histology Atlas (DE-588)4143303-8 gnd Histologie (DE-588)4025092-1 gnd |
| subject_GND | (DE-588)4143303-8 (DE-588)4025092-1 |
| title | Gartner and Hiatt's atlas and text of histology |
| title_alt | Atlas and text of histology Color atlas and text of histology |
| title_auth | Gartner and Hiatt's atlas and text of histology |
| title_exact_search | Gartner and Hiatt's atlas and text of histology |
| title_exact_search_txtP | Gartner and Hiatt's atlas and text of histology |
| title_full | Gartner and Hiatt's atlas and text of histology Leslie P. Gartner, PhD, Lisa M. J. Lee, PhD |
| title_fullStr | Gartner and Hiatt's atlas and text of histology Leslie P. Gartner, PhD, Lisa M. J. Lee, PhD |
| title_full_unstemmed | Gartner and Hiatt's atlas and text of histology Leslie P. Gartner, PhD, Lisa M. J. Lee, PhD |
| title_short | Gartner and Hiatt's atlas and text of histology |
| title_sort | gartner and hiatt s atlas and text of histology |
| topic | Atlas (DE-588)4143303-8 gnd Histologie (DE-588)4025092-1 gnd |
| topic_facet | Atlas Histologie |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=033584537&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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