Gene expression studies have revealed diagnostic profiles and upregulation of specific pathways in many solid tumors. The explosion of new information in gene expression profiling could potentially lead to the development of tailored treatments in many solid tumors. In addition many studies are ongo...

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Bibliographic Details

Other Authors:	Russo, Antonio (Editor), Iacobelli, Stefano (Editor), Iovanna, Juan (Editor)
Format:	Electronic eBook
Language:	English
Published:	Totowa, NJ Humana Press 2012
Edition:	1st ed. 2012
Series:	Current Clinical Pathology
Subjects:	Pathology Oncology Laboratory Medicine Oncology   Laboratory medicine
Online Access:	UBR01 Volltext
Summary:	Gene expression studies have revealed diagnostic profiles and upregulation of specific pathways in many solid tumors. The explosion of new information in gene expression profiling could potentially lead to the development of tailored treatments in many solid tumors. In addition many studies are ongoing to validate these signatures also in predicting response to hormonal, chemotherapeutic and targeted agents in breast cancer as well as in other tumors.   Diagnostic, Prognostic and Therapeutic Value of Gene Signatures provides readers a useful and comprehensive resource about the range of applications of microarray technology in oncological diseases. Topics covered include gene signatures and soft tissue sarcomas, prognostic relevance of breast cancer signatures, gene expression profiling of colorectal cancer and liver metastasis, gene signatures in GISTs, CNVs and gene expression profiles in pancreatic cancer, and gene signatures in head/neck, lung and gastric tumors.   Diagnostic, Prognostic and Therapeutic Value of Gene Signatures will be of great value to residents and fellows, physicians, pathologists and  medical oncologists
Physical Description:	1 Online-Ressource (XI, 182 Seiten 28 illus., 24 illus. in color.)
ISBN:	9781617793585
DOI:	10.1007/978-1-61779-358-5