Scleroderma From Pathogenesis to Comprehensive Management (Springer New York, 2012)
Foreword -- Preface -- Historical Perspective.-Therapeutic evolution: a professor's view -- Overview: Epidemiology, Genetics and Classification.-Epidemiology and Environmental Risk Factors.- Genetic Factors -- Disease Subsets in Clinical Practice.-Evolving Concepts of Diagnosis and Classification -- Disease Classification using Molecular Signatures.-Localized Scleroderma -- Juvenile Systemic Scleroderma.-Scleroderma Mimics -- Localized Forms of Scleroderma in Adults.-Overview: Integrated Pathogenesis -- Immunological Mechanisms.-Innate Immunity -- Autoantibodies in Pathogenesis -- The Clinical Aspects of Autoantibodies -- Mechanisms of Vascular Disease.-Vascular Biomarkers -- Mechanisms of Fibrosis -- Fibrosis: Insights from the stiff skin syndrome -- Biomarkers of Fibrosis -- Overview of Animal Models.-Overview: Cardiovascular Manifestations and Management.-Raynaud Phenomenon.-Nailfold Capillaroscopy -- Systemic Vascular Disease -- Scleroderma Renal Crisis -- Cardiac Involvement.-Erectile Dysfunction.-Overview: Pulmonary manifestations and management.-Clinical Assessment of Lung Disease -- Computerized Tomography of Interstitial Lung Disease.-Treatment of interstitial lung disease.-Clinical Assessment of Pulmonary Hypertension.-Treatment of Pulmonary Hypertension -- Complex Challenges of Pulmonary Hypertension -- Overview: Gastrointestinal Manifestations and Management -- Upper Gastrointestinal Tract.-Small and Large Intestinal Involvement.-Evaluation and Management of Skin Disease.-Skeletal Muscle Involvement.-  Tendons, Joints and Bone -- Pregnancy.-Overlooked Manifestations -- Principles of Management.-Immunomodulatory Therapies.-Cell-Based Therapies -- Investigative Approaches to Drug Therapy.-Complementary and alternate medicine approaches.-Physical and occupational therapy -- Evaluation and Management of Psychosocial Issues.-Issues in Clinical Trial Design -- Measuring Disease Activity -- Patient Reported Outcomes.