Biochemistry of lipids, lipoproteins and membranes:

Biochemistry of Lipids, Lipoproteins and Membranes, Seventh Edition serves as a comprehensive, general reference book for scientists and students studying lipids, lipoproteins and membranes. Here, across 19 chapters, leaders in the field summarize fundamental concepts, recent research developments,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Weitere Verfasser: Ridgway, Neale (HerausgeberIn), McLeod, Roger (HerausgeberIn)
Format: Buch
Sprache:English
Veröffentlicht: Amsterdam, Netherlands Elsevier [2021]
Ausgabe:Seventh edition
Schlagworte:
Zusammenfassung:Biochemistry of Lipids, Lipoproteins and Membranes, Seventh Edition serves as a comprehensive, general reference book for scientists and students studying lipids, lipoproteins and membranes. Here, across 19 chapters, leaders in the field summarize fundamental concepts, recent research developments, data analysis, and implications for human disease and intervention. Topics discussed include lipid biology in both prokaryotes and eukaryotes, fatty acid synthesis, desaturation and elongation, and pathways leading to synthesis of complex phospholipids, sphingolipids and their structural variants. Chapters also examine how bioactive lipids are involved in cell signaling, with an emphasis on disease implications and pathological consequences.As the field advances, each chapter in this new edition has been fully revised to address emerging topics, with all-new coverage of lipid droplets and their role as regulatory organelles for energy homeostasis, as well as their relationship to obesity, liver disease and diabetes. Evolving research in fatty acid handling and storage in eukaryotes is also discussed in-depth, with new sections addressing fatty acid uptake, activation and lipolysis.- Fully revised to cover new and emerging topics- Provides an important bridge between broad-based biochemistry research and application- Presents key concepts that are supported by figures and models to improve understanding- Includes references from current literature in each chapter to facilitate in-depth study
Beschreibung:1. Functional roles of lipids in biological membranes; Mikhail Bogdanov and William Dowhan; 2. Methods of lipid analysis; Bebiana C. Sousa, Michael J.O. Wakelam and Andrea F. Lopez-Clavijo; 3. Fatty acid and phospholipid biosynthesis in prokaryotes; Jessica M. Gullett and Charles O. Rock; 4. Lipid metabolism in plants; Katherine M. Schmid; 5. Fatty acid handling in mammalian cells; Richard Lehner and Ariel D. Quiroga; 6. Fatty acid desaturation and elongation in mammals; Lucas M. O'Neill, Makoto Miyazaki, Laura M. Bond, Sarah A. Lewis, Fang Ding, Zhaojin Liu and James M. Ntambi; 7. Phospholipid synthesis in mammalian cells; Neale Ridgway; 8. Phospholipid catabolism; Dakai Zhang and Guangwei Du; 9. Sphingolipids; Anthony H. Futerman; 10. Cholesterol synthesis; Andrew J. Brown, Hudson W. Coates and Laura J. Sharpe; 11. Structure and function of lipid droplets; Hongyuan Yang and Jun Liu; 12. Bile acid metabolism; Jennifer K. Truong and Paul A. Dawson; 13. Lipid modification of proteins; Marilyn D. Resh; 14. Inter- and intra-membrane lipid transport; Vesa M. Olkkonen and Elina Ikonen; 15. High-density lipoproteins metabolism and protective roles; Valentin Blanchard and Gordon A. Francis; 16. Assembly and secretion of triglyceride-rich lipoproteins; Eric A. Fisher and Roger S. McLeod; 17. Lipoprotein(a); Michael B. Boffa and Marlys L. Koschinsky; 18. Lipoprotein receptors; Kristina Kuhbandner, Joachim Herz and Theresa Pohlkamp; 19. Atherosclerosis; Murray W. Huff and Katey J. Rayner; 20. Diabetic dyslipidaemia; Khosrow Adeli, Changting Xiao, Victoria Higgins, Jennifer Taher, Sarah Farr and Gary F. Lewis
Beschreibung:xxviii, 707 Seiten Illustrationen 229 mm
ISBN:9780128240489