Many new drugs on the market are chiral compounds, that is, they can exist in two non-superimposable mirror-image forms. Asymmetric catalysis encompasses a large variety of processes for obtaining such compounds. The performance of the catalyst in those processes largely depends on the ligand that m...

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Bibliographic Details

Other Authors:	Diéguez, Montserrat (Editor)
Format:	Book
Language:	English
Published:	Boca Raton ; London ; New York CRC Press, Taylor & Francis Group [2021]
Edition:	First edition
Series:	New directions in organic and biological chemistry
Subjects:	bisacsh / SCIENCE / Life Sciences / Biochemistry Asymmetrische Synthese Chiralität > Chemie Katalyse Ligand Aufsatzsammlung
Summary:	Many new drugs on the market are chiral compounds, that is, they can exist in two non-superimposable mirror-image forms. Asymmetric catalysis encompasses a large variety of processes for obtaining such compounds. The performance of the catalyst in those processes largely depends on the ligand that makes up the catalyst. This book describes the most relevant ligand libraries for some key processes, including an overview of the state of art and the key mechanistic aspects that favor a high catalytic performance.Key Features:The book presents historical content from the time of discovery for each family of ligands.Provides a description of the synthetic route and the ligand library's application in various catalytic asymmetric reactionsSuitable as supplementary reading for courses targeting the design, synthesis and application of chiral catalysts, asymmetric catalysis and sustainable productionEdited by a distinguished scientist in the field, the book has a diverse audience including research groups in homogeneous catalysis, particularly asymmetric transformations
Item Description:	Preface; About the Editor; List of Contributors; Chapter 1 Chiral bidentate heterodonor P-oxazoline ligands, Maria Biosca, Jordi Faiges, Montserrat Diéguez and Oscar Pàmies; Chapter 2 Chiral bidentate heterodonor P-N-other-ligands, Pep Rojo, Marina Bellido, Xavier Verdaguer and Antoni Riera; Chapter 3 Chiral bidentate heterodonor P-S/O ligands, Jèssica Margalefa and Miquel A. Pericàs; Chapter 4 Chiral Bidentate Heterodonor P-P’ ligands, Antonio Pizzano; Chapter 5 Chiral tridentate based ligands, Uchchhal Bandyopadhyay, Basker Sundararaju, Rinaldo Poli and Eric Manourya; Chapter 6 Chiral N-heterocyclic carbene-based ligands, Vincent César, Christophe Fliedel, Agnès Labande; Chapter 7 Chiral Monophosphorus Ligands, Wenjun Tang, Feng Wan and He Yang; Chapter 8 Solvent oriented ligand and catalyst design in asymmetric catalysis – Principles and limits, Armin Borner
Physical Description:	xvi, 322 Seiten Illustrationen
ISBN:	9780367428488 9780367761707