The ethics of personalised medicine: critical perspectives
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| Other Authors: | , , , |
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| Format: | Book |
| Language: | English |
| Published: |
London
Routledge, Taylor & Francis
2020
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| Subjects: | |
| Online Access: | Inhaltsverzeichnis Klappentext |
| Physical Description: | xxviii, 285 Seiten |
| ISBN: | 9780367599096 9781472447968 |
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| adam_text | քքէ TP BibllotheksWrbund DV D Bayern Kataloganreicherung von UB Augsburg K000384591 Bestell-Nr.: System-Nr.: BV-Nr.: K000384591 032613747 BV047208903 Bestelldatum: 31.05.2021 Titel: -iThe-i ethics of personalised medicine Verfasser: Vollmann, Jochen ISBN: 978-0-367-59909-6 Ort: London Jahr: 2020 Anreicherungstyp: Inhaltsverzeichnis Aufloesung: 300dpi (Standard) Farbe: s/w (Text) Zeichensatz: IS08859-1 Bearbeiter: TM Hinweise: Digitalisierung UB Augsburg - ADAM Catalogue Enrichment
Contents List of Figures ix List of Tables xi Λ otes on Contributors Introduction xiii 1 Jochen Vollmann, Verena Sandow, Sebastian Wäscher and Jan Schildmann PART I: PERSONALISED MEDICINE - MEDICINE FOR THE PERSON? CONCEPTS AND CONTEXTUAL ASPECTS 1 What is Personalised Medicine? Sharpening a Vague Term Based on a Systematic Literature Review 9 Sebastian Schleidgen, Corinna Klingkr. Teresa Bertram, Wolf H. Rogowski and Georg Marckmann 2 Alarming Symptoms of a Paradigm Shift? An Approach to Bridge the Gap between Hypothetical Ethics and the Current Status of Individualised Medicine Research 25 Tobias Fischer, Marcus Dörr, Robin Haring and Mariin Langanke 3 Personalised Medicine: Getting Past the Controversies 41 George P. Browman 4 Patient as Person in Personalised Medicine: Autonomy, Responsibility and the Body 53 Thomas Wabel 5 The Authority of Corporeality and Emotions: The New Phenomenology and its Relevance to the German Debate on Personalised Medicine Mathias Wirth 65
THE ETHICS OF PERSONALISED MEDICINE 6 Towards Integration of ‘Personalised’ and Person-Centred Medicine: The Concept of ‘Integrative and Personalised I lealth Care’ Peter И eusser PART II: PERSONALISED MEDICINE IN CLINICAL AND PRACTICAL RESEARCH 7 8 9 Ethical Considerations for Developing a Best-Practice Guideline for Next Generation Sequencing in Oncology Eva C. Winkler. Klaus Tanner. Hanno Glimm and (.bristo/ ron Kalle Š Practice Variation across Consent Templates for Biobank Research: A Survey of German Biobanks Irene Hirschberg, Hannes Kalmiss and Dame! Střech 9 Individualised Medicine in the Diagnosis and Prognosis ot Patients Younger than 65 Years with Normal Karvotvpe Acule Mveloid Leukemia: A Systematic Review and Mcta-Analvsis ot the Impaci of Fms-Related Tyrosine Kinase 3 Internal Tandem Duplication (FLT3-ITD) М3 Matthias Port, Miriam Böttcher. } ilícitas Thal Alcole Trachte. Jurgen Wasem. Arnold Ganser. Նաra Pomyamout and Anja Acıtmamı 10 11 12 Taking it Personally: Patients’ Perspectives on Personalised Medicine and its Educai Relevance Sabine Wöhlke. Julia Репу and Silke Schicktaug 129 ‘Personalised Medicine’ in Oncology: Physicians’ Perspectives on Contributions to and Challenges for Clinical Practice Sebastian Wäscher Jan Schildmann. Caroline Brail and ¡ochen 1 oilmann 149 Through Thick and Big: Data-Rich Medicine in the Era of Personalisation Barbara Prainsack լ 61 PART III: PERSONALISED MEDICINE IN HEALTH-CARE SYSTEMS 13 Benefit Assessment of Personalised Interventions: Methodological Challenges and Approaches to a Solution Jürgen Windeier and Stefan
Lange VI 175
CONTENTS 14 The Relevance of the Analytic ralidity of Genetic Biomarker Tests in Personalised Medicine in Oncology 187 Fran զ Hessel 15 Approval and Reimbursement of Personalised Drugs: Interim Results of the Adjustment Process 199 Michael Noweski, Anke W alendgik, Frang Hessel. Rebecca Jahn and Jürgen Wasem 16 Criteria for Fairly Allocating Scarce Health-Care Resources to Genetic Tests: Which Matter Most? 211 Wolf H. Rogowski. Scott D. Grosse, Jörg Schmidtke and Georg Slarchnam 17 Personalised Medicine as Orphan Drugs? Legal and Ethical Questions 231 Sina Gottwald and Stefan Haster 18 Personalised Medicine: Priority Setting and Opportunity Costs in European Public Health-Care Systems 245 jochen λ olimann PART IV: PERSONALISED MEDICINE IN ONCOLOGY: RECOMMENDATIONS FOR FUTURE DEVELOPMENT 19 ‘Personalised Medicine’: Multidisciplinary Perspectives and Interdisciplinary Recommendations on a Framework for Future Research and Practice Jan Schildmann, Slinam Böttcher, Maria Gabriel, .Arnold Ganser. 259 Sina Gottwald, Frang Fiessei, Stefan Haster; Rebecca Jahn, Anja Neumann, Michael Noweski, Matthias Poti, Laura Pourjamout, Verena Sandow, Felicitas Thal, Sebastian Wäscher. Anke Walendgik. ]argen Wasem and Jochen Vollmann Index 281
BVBIiyePnheteVerbimd Kataloganreicherung von UB Augsburg K000384592 Bestell-Nr.: System-Nr.: BV-Nr.: K000384592 032613747 BV047208903 Bestelldatum: 31.05.2021 Titel: ՜՛The-ւ ethics of personalised medicine Verfasser: Vollmann, Jochen ISBN: 978-0-367-59909-6 Ort: London Jahr: 2020 Anreicherungstyp: Klappentext Aufloesung: 300dpi (Standard) Farbe: s/w (Text) Zeichensatz: IS08859-1 Bearbeiter: TM Hinweise: Digitalisierung UB Augsburg - ADAM Catalogue Enrichment
The Ethics of Personalised Medicine Critical Perspectives Edited by Jochen Vollmann, Verena Sandow, Sebastian Wäscher and Jan Schildmann, all at Institute for Medical Ethics and History of Medicine, Ruhr-University Bochum, Germany ln recent times, the phrase ‘personalised medicine’ has become the symbol of medical progress and a label for better health care in the future. However, a controversial debate has developed around whether these promises of better, more personal and more cost-efficient medicine are realistic. This book brings together leading researchers from across Europe and North America, from both normative and empirical disciplines, w ho take a more critical view of the often encountered hype associated with personalised medicine. Partially drawing on a four year collaborative research project funded by the German Ministry for Education and Research, the book presents a multidisciplinary debate on the current state of research on the ethical, legal and social implications of personalised medicine. At a time when future health care is a topic of much discussion, this book provides valuable policy recommendations for the way forward. This study will be ot interest to researchers from various disciplines including philosophy, bioethics, law-and social sciences. This volume is a landmarkfor demythologising the buzzword ‘personalised medicine , critically differentiating between hype andfalse hopes on the one hand and realistic approaches and outlooks on the other. By comprehensively comprising a wide range of excellent normative and empirical studies, it empowers
anyone interested in better understanding the presuppositions and consequences of the term personalised medicine՝ to form a well-iifformed judgement on one of the most augured ideas in cutting-edge medicine. Peter Dabrock, University of Erlangen, Germany, and Vice Chair of the German Ethics Council and member of the European Group on Ethics in Science and New Technologies (EGE)
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քքէ TP BibllotheksWrbund DV D Bayern Kataloganreicherung von UB Augsburg K000384591 Bestell-Nr.: System-Nr.: BV-Nr.: K000384591 032613747 BV047208903 Bestelldatum: 31.05.2021 Titel: -iThe-i ethics of personalised medicine Verfasser: Vollmann, Jochen ISBN: 978-0-367-59909-6 Ort: London Jahr: 2020 Anreicherungstyp: Inhaltsverzeichnis Aufloesung: 300dpi (Standard) Farbe: s/w (Text) Zeichensatz: IS08859-1 Bearbeiter: TM Hinweise: Digitalisierung UB Augsburg - ADAM Catalogue Enrichment
Contents List of Figures ix List of Tables xi Λ otes on Contributors Introduction xiii 1 Jochen Vollmann, Verena Sandow, Sebastian Wäscher and Jan Schildmann PART I: PERSONALISED MEDICINE - MEDICINE FOR THE PERSON? CONCEPTS AND CONTEXTUAL ASPECTS 1 What is Personalised Medicine? Sharpening a Vague Term Based on a Systematic Literature Review 9 Sebastian Schleidgen, Corinna Klingkr. Teresa Bertram, Wolf H. Rogowski and Georg Marckmann 2 Alarming Symptoms of a Paradigm Shift? An Approach to Bridge the Gap between Hypothetical Ethics and the Current Status of Individualised Medicine Research 25 Tobias Fischer, Marcus Dörr, Robin Haring and Mariin Langanke 3 Personalised Medicine: Getting Past the Controversies 41 George P. Browman 4 Patient as Person in Personalised Medicine: Autonomy, Responsibility and the Body 53 Thomas Wabel 5 The Authority of Corporeality and Emotions: The New Phenomenology and its Relevance to the German Debate on Personalised Medicine Mathias Wirth 65
THE ETHICS OF PERSONALISED MEDICINE 6 Towards Integration of ‘Personalised’ and Person-Centred Medicine: The Concept of ‘Integrative and Personalised I lealth Care’ Peter И eusser PART II: PERSONALISED MEDICINE IN CLINICAL AND PRACTICAL RESEARCH 7 8 9 Ethical Considerations for Developing a Best-Practice Guideline for Next Generation Sequencing in Oncology Eva C. Winkler. Klaus Tanner. Hanno Glimm and (.bristo/ ron Kalle Š Practice Variation across Consent Templates for Biobank Research: A Survey of German Biobanks Irene Hirschberg, Hannes Kalmiss and Dame! Střech 9 Individualised Medicine in the Diagnosis and Prognosis ot Patients Younger than 65 Years with Normal Karvotvpe Acule Mveloid Leukemia: A Systematic Review and Mcta-Analvsis ot the Impaci of Fms-Related Tyrosine Kinase 3 Internal Tandem Duplication (FLT3-ITD) " М3 Matthias Port, Miriam Böttcher. } ilícitas Thal Alcole Trachte. Jurgen Wasem. Arnold Ganser. Նաra Pomyamout and Anja Acıtmamı 10 11 12 Taking it Personally: Patients’ Perspectives on Personalised Medicine and its Educai Relevance Sabine Wöhlke. Julia Репу and Silke Schicktaug 129 ‘Personalised Medicine’ in Oncology: Physicians’ Perspectives on Contributions to and Challenges for Clinical Practice Sebastian Wäscher Jan Schildmann. Caroline Brail and ¡ochen 1 oilmann 149 Through Thick and Big: Data-Rich Medicine in the Era of Personalisation Barbara Prainsack լ 61 PART III: PERSONALISED MEDICINE IN HEALTH-CARE SYSTEMS 13 Benefit Assessment of Personalised Interventions: Methodological Challenges and Approaches to a Solution Jürgen Windeier and Stefan
Lange VI 175
CONTENTS 14 The Relevance of the Analytic \ralidity of Genetic Biomarker Tests in Personalised Medicine in Oncology 187 Fran զ Hessel 15 Approval and Reimbursement of Personalised Drugs: Interim Results of the Adjustment Process 199 Michael Noweski, Anke W'alendgik, Frang Hessel. Rebecca Jahn and Jürgen Wasem 16 Criteria for Fairly Allocating Scarce Health-Care Resources to Genetic Tests: Which Matter Most? 211 Wolf H. Rogowski. Scott D. Grosse, Jörg Schmidtke and Georg Slarchnam 17 Personalised Medicine as Orphan Drugs? Legal and Ethical Questions 231 Sina Gottwald and Stefan Haster 18 Personalised Medicine: Priority Setting and Opportunity Costs in European Public Health-Care Systems 245 jochen λ'olimann PART IV: PERSONALISED MEDICINE IN ONCOLOGY: RECOMMENDATIONS FOR FUTURE DEVELOPMENT 19 ‘Personalised Medicine’: Multidisciplinary Perspectives and Interdisciplinary Recommendations on a Framework for Future Research and Practice Jan Schildmann, Slinam Böttcher, Maria Gabriel, .Arnold Ganser. 259 Sina Gottwald, Frang Fiessei, Stefan Haster; Rebecca Jahn, Anja Neumann, Michael Noweski, Matthias Poti, Laura Pourjamout, Verena Sandow, Felicitas Thal, Sebastian Wäscher. Anke Walendgik. ]argen Wasem and Jochen Vollmann Index 281
BVBIiyePnheteVerbimd Kataloganreicherung von UB Augsburg K000384592 Bestell-Nr.: System-Nr.: BV-Nr.: K000384592 032613747 BV047208903 Bestelldatum: 31.05.2021 Titel: ՜՛The-ւ ethics of personalised medicine Verfasser: Vollmann, Jochen ISBN: 978-0-367-59909-6 Ort: London Jahr: 2020 Anreicherungstyp: Klappentext Aufloesung: 300dpi (Standard) Farbe: s/w (Text) Zeichensatz: IS08859-1 Bearbeiter: TM Hinweise: Digitalisierung UB Augsburg - ADAM Catalogue Enrichment
The Ethics of Personalised Medicine Critical Perspectives Edited by Jochen Vollmann, Verena Sandow, Sebastian Wäscher and Jan Schildmann, all at Institute for Medical Ethics and History of Medicine, Ruhr-University Bochum, Germany ln recent times, the phrase ‘personalised medicine’ has become the symbol of medical progress and a label for better health care in the future. However, a controversial debate has developed around whether these promises of better, more personal and more cost-efficient medicine are realistic. This book brings together leading researchers from across Europe and North America, from both normative and empirical disciplines, w'ho take a more critical view of the often encountered hype associated with personalised medicine. Partially drawing on a four year collaborative research project funded by the German Ministry for Education and Research, the book presents a multidisciplinary debate on the current state of research on the ethical, legal and social implications of personalised medicine. At a time when future health care is a topic of much discussion, this book provides valuable policy recommendations for the way forward. This study will be ot interest to researchers from various disciplines including philosophy, bioethics, law-and social sciences. This volume is a landmarkfor demythologising the buzzword ‘personalised medicine', critically differentiating between hype andfalse hopes on the one hand and realistic approaches and outlooks on the other. By comprehensively comprising a wide range of excellent normative and empirical studies, it empowers
anyone interested in better understanding the presuppositions and consequences of the term personalised medicine՝ to form a well-iifformed judgement on one of the most augured ideas in cutting-edge medicine. Peter Dabrock, University of Erlangen, Germany, and Vice Chair of the German Ethics Council and member of the European Group on Ethics in Science and New Technologies (EGE) |
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| spelling | The ethics of personalised medicine critical perspectives edited by Jochen Vollmann, Verena Sandow, Sebastian Wäscher and Jan Schildmann London Routledge, Taylor & Francis 2020 © 2015 xxviii, 285 Seiten txt rdacontent n rdamedia nc rdacarrier Medizinische Ethik (DE-588)4074672-0 gnd rswk-swf Individualisierte Medizin (DE-588)7660544-9 gnd rswk-swf Individualisierte Medizin (DE-588)7660544-9 s Medizinische Ethik (DE-588)4074672-0 s DE-604 Vollmann, Jochen 1963- (DE-588)112407773 edt Sandow, Verena ca. 20./21. Jh. (DE-588)1016966628 edt Schildmann, Jan 1974- (DE-588)129701793 edt Wäscher, Sebastian 1982- (DE-588)1030064628 edt Digitalisierung UB Augsburg - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=032613747&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Digitalisierung UB Augsburg - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=032613747&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Klappentext |
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| title | The ethics of personalised medicine critical perspectives |
| title_auth | The ethics of personalised medicine critical perspectives |
| title_exact_search | The ethics of personalised medicine critical perspectives |
| title_exact_search_txtP | The ethics of personalised medicine critical perspectives |
| title_full | The ethics of personalised medicine critical perspectives edited by Jochen Vollmann, Verena Sandow, Sebastian Wäscher and Jan Schildmann |
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| title_full_unstemmed | The ethics of personalised medicine critical perspectives edited by Jochen Vollmann, Verena Sandow, Sebastian Wäscher and Jan Schildmann |
| title_short | The ethics of personalised medicine |
| title_sort | the ethics of personalised medicine critical perspectives |
| title_sub | critical perspectives |
| topic | Medizinische Ethik (DE-588)4074672-0 gnd Individualisierte Medizin (DE-588)7660544-9 gnd |
| topic_facet | Medizinische Ethik Individualisierte Medizin |
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