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Epigenetics:

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Bibliographic Details
Other Authors:	Pandey, Subhash C. (Editor)
Format:	Book
Language:	English
Published:	Cambridge, MA ; San Diego, CA Academic Press, an imprint of Elsevier 2021
Edition:	First edition
Series:	International review of neurobiology volume 156
Subjects:	Epigenetik Aufsatzsammlung
Online Access:	Inhaltsverzeichnis
Physical Description:	xiii, 277 Seiten Illustrationen, Diagramme
ISBN:	9780128172384

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adam_text	Contents Contributors ix Preface xi 1. Histone modifications, DNA méthylation, and the epigenetic code of alcohol use disorder 1 John Peyton Bohnsack and Subhash C. Pandey 1. Introduction 2. Epigenetics and gene expression 2 5 3. Histone acetylation mechanisms in alcoholuse and dependence 15 4. Histone méthylation mechanismsIn alcohol abuse and dependence 27 5. DNA méthylation and gene expression 37 6. DNA méthylation mechanisms inalcohol abuse and dependence 40 7. New technologies for studying histone posttranslational modifications and epigenetic regulation 44 8. Conclusions 46 Acknowledgment and disclosure 48 Conflict of interest 48 References 48 2. Epigenetic and non-coding regulation of alcohol abuse and addiction 63 Sean P. Farris and R. Dayne Mayfield 1. Introduction 64 2. Genetics, epigenetics, and eplgenomics 65 3. Histones and post-translatlonal modifications 67 4. Non-coding sequences 68 5. Méthylation, acetylation, and ublquitination 73 6. The role of non-coding RNAs in addiction 75 7. Conclusion and future directions 79 Acknowledgment 79 Disclosure 79 References 79 V Contents VI 3. Epigenetic mechanisms underlying stress-induced depression 87 Luana Martins de Carvalho, Wei-Yang Chen, and Amy W. Lasek 1. Introduction 88 2. Methods to induce depressive-like behavior in rodents 94 3. Tests of depressive-like behavior in rodents 99 4. Histone acetylation and deacetylation in depressive-like behavior 101 5. Histone méthylation and déméthylation in MDD 106 6. DNA méthylation and déméthylation in MDD 109 7. Histone modifications, DNA méthylation, inflammation, and MDD 113 8. Sex differences in epigenetic mechanisms underlying depression 116 9. Conclusions 116 Acknowledgment 117 References 117 4. Epigenetic landscape of stress surfeit disorders: Key role for DNA méthylation dynamics 127 Eleonora Gatta, Vikram Saudagar, James Auta, Dennis R. Grayson, and Alessandro Guidotti 1. Introduction 128 2. Epigenetic actors of DNA méthylation 135 3. Environmental stress: A trigger of epigenetic reprogramming 142 4. DNA méthylation impairments in major depressive disorder 148 5. Alcohol use disorder: A DNA méthylation reprogramming 150 6. Evidence for epigenetic alterations in post-traumatic stress disorder 156 7. Conclusion 157 Acknowledgment 158 References 158 5. Prenatal stress induced chromatin remodeling and risk of psychopathology in adulthood 185 Erbo Dong and Subhash C. Pandey 1. Introduction 186 2. Prenatal stress is associated with psychiatric disorders in adult offspring 187 3. Epigenetics of psychotic disorders 190 4. Prenatal stress animal models of psychiatric disorders and epigenetic mechanisms 200 5. Conclusions 204 Acknowledgment 205 References 205 Further reading 215 Contents б. Exposure to drugs of abuse induce effects that persist across generations vii 217 Annalisa M. Baratta, Richa S. Rathod, Sonja L. Plašil, Amit Seth, and Gregg E. Homanics 1. Introduction 218 2. Overview of epigenetics 222 3. Drug-induced epigeneticmodifications 227 4. Overview of transgenerational effects of substance abuse 228 5. Ethanol 228 6. Cocaine 236 7. Nicotine 240 8. Cannabinoids 245 9. Opiates 250 10. Conclusions and future directions 258 Acknowledgment 263 References 263
adam_txt	Contents Contributors ix Preface xi 1. Histone modifications, DNA méthylation, and the epigenetic code of alcohol use disorder 1 John Peyton Bohnsack and Subhash C. Pandey 1. Introduction 2. Epigenetics and gene expression 2 5 3. Histone acetylation mechanisms in alcoholuse and dependence 15 4. Histone méthylation mechanismsIn alcohol abuse and dependence 27 5. DNA méthylation and gene expression 37 6. DNA méthylation mechanisms inalcohol abuse and dependence 40 7. New technologies for studying histone posttranslational modifications and epigenetic regulation 44 8. Conclusions 46 Acknowledgment and disclosure 48 Conflict of interest 48 References 48 2. Epigenetic and non-coding regulation of alcohol abuse and addiction 63 Sean P. Farris and R. Dayne Mayfield 1. Introduction 64 2. Genetics, epigenetics, and eplgenomics 65 3. Histones and post-translatlonal modifications 67 4. Non-coding sequences 68 5. Méthylation, acetylation, and ublquitination 73 6. The role of non-coding RNAs in addiction 75 7. Conclusion and future directions 79 Acknowledgment 79 Disclosure 79 References 79 V Contents VI 3. Epigenetic mechanisms underlying stress-induced depression 87 Luana Martins de Carvalho, Wei-Yang Chen, and Amy W. Lasek 1. Introduction 88 2. Methods to induce depressive-like behavior in rodents 94 3. Tests of depressive-like behavior in rodents 99 4. Histone acetylation and deacetylation in depressive-like behavior 101 5. Histone méthylation and déméthylation in MDD 106 6. DNA méthylation and déméthylation in MDD 109 7. Histone modifications, DNA méthylation, inflammation, and MDD 113 8. Sex differences in epigenetic mechanisms underlying depression 116 9. Conclusions 116 Acknowledgment 117 References 117 4. Epigenetic landscape of stress surfeit disorders: Key role for DNA méthylation dynamics 127 Eleonora Gatta, Vikram Saudagar, James Auta, Dennis R. Grayson, and Alessandro Guidotti 1. Introduction 128 2. Epigenetic actors of DNA méthylation 135 3. Environmental stress: A trigger of epigenetic reprogramming 142 4. DNA méthylation impairments in major depressive disorder 148 5. Alcohol use disorder: A DNA méthylation reprogramming 150 6. Evidence for epigenetic alterations in post-traumatic stress disorder 156 7. Conclusion 157 Acknowledgment 158 References 158 5. Prenatal stress induced chromatin remodeling and risk of psychopathology in adulthood 185 Erbo Dong and Subhash C. Pandey 1. Introduction 186 2. Prenatal stress is associated with psychiatric disorders in adult offspring 187 3. Epigenetics of psychotic disorders 190 4. Prenatal stress animal models of psychiatric disorders and epigenetic mechanisms 200 5. Conclusions 204 Acknowledgment 205 References 205 Further reading 215 Contents б. Exposure to drugs of abuse induce effects that persist across generations vii 217 Annalisa M. Baratta, Richa S. Rathod, Sonja L. Plašil, Amit Seth, and Gregg E. Homanics 1. Introduction 218 2. Overview of epigenetics 222 3. Drug-induced epigeneticmodifications 227 4. Overview of transgenerational effects of substance abuse 228 5. Ethanol 228 6. Cocaine 236 7. Nicotine 240 8. Cannabinoids 245 9. Opiates 250 10. Conclusions and future directions 258 Acknowledgment 263 References 263
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spelling	Epigenetics edited by Subhash C. Pandey (Center for Alcohol Research in Epigenetics, Department of Psychiatry; Department of Anatomy and Cell Biology, University of Illinois at Chicago; Jesse Brown VA Medical Center, Chicago, IL, United States) First edition Cambridge, MA ; San Diego, CA Academic Press, an imprint of Elsevier 2021 xiii, 277 Seiten Illustrationen, Diagramme txt rdacontent n rdamedia nc rdacarrier International review of neurobiology volume 156 Epigenetik (DE-588)7566079-9 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Epigenetik (DE-588)7566079-9 s DE-604 Pandey, Subhash C. (DE-588)1060238152 edt Erscheint auch als Online-Ausgabe 978-0-12-817239-1 International review of neurobiology volume 156 (DE-604)BV002534817 156 Digitalisierung UB Regensburg - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=032552592&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis
spellingShingle	Epigenetics International review of neurobiology Epigenetik (DE-588)7566079-9 gnd
subject_GND	(DE-588)7566079-9 (DE-588)4143413-4
title	Epigenetics
title_auth	Epigenetics
title_exact_search	Epigenetics
title_exact_search_txtP	Epigenetics
title_full	Epigenetics edited by Subhash C. Pandey (Center for Alcohol Research in Epigenetics, Department of Psychiatry; Department of Anatomy and Cell Biology, University of Illinois at Chicago; Jesse Brown VA Medical Center, Chicago, IL, United States)
title_fullStr	Epigenetics edited by Subhash C. Pandey (Center for Alcohol Research in Epigenetics, Department of Psychiatry; Department of Anatomy and Cell Biology, University of Illinois at Chicago; Jesse Brown VA Medical Center, Chicago, IL, United States)
title_full_unstemmed	Epigenetics edited by Subhash C. Pandey (Center for Alcohol Research in Epigenetics, Department of Psychiatry; Department of Anatomy and Cell Biology, University of Illinois at Chicago; Jesse Brown VA Medical Center, Chicago, IL, United States)
title_short	Epigenetics
title_sort	epigenetics
topic	Epigenetik (DE-588)7566079-9 gnd
topic_facet	Epigenetik Aufsatzsammlung
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