Neural correlates of working memory training: fMRI analyses in healthy older adults
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| Main Author: | |
|---|---|
| Format: | Thesis Electronic Software eBook |
| Language: | English |
| Published: |
[Leipzig]
2020
|
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Physical Description: | 1 CD-ROM (197 Seiten) Illustrationen |
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| 245 | 1 | 0 | |a Neural correlates of working memory training |b fMRI analyses in healthy older adults |c vorgelegt von Master of Science Psychologin Nicole Hudl |
| 264 | 1 | |a [Leipzig] |c 2020 | |
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Record in the Search Index
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| adam_text | TABLE
OF
CONTENT
LIST
OF
ABBREVIATIONS
.................................................................................................
11
THEORETICAL
BACKGROUND
..........................................................................................
15
1.
COGNITIVE
AGING
.................................................................................................
17
2.
WORKING
MEMORY
..............................................................................................
25
2.1.
WORKING
MEMORY
MODELS
..............................................................................
26
2.1.1.
MULTICOMPONENT
MODEL
OF
WORKING
MEMORY
BY
BADDELEY
AND
HITCH
.........
27
2.1.2.
WORKING
MEMORY
MODEL
BY
ENGLE
.............................................................
34
2.1.3.
EMBEDDED-PROCESS
MODEL
BY
COWAN
.......................................................
35
2.2.
NEURAL
MECHANISMS
OF
WORKING
MEMORY
.......................................................
37
3.
WORKING
MEMORY
TRAINING:
CURRENT
STATE
OF
RESEARCH
.......................................
43
4.
METHODS
............................................................................................................
51
4.1.
META-ANALYSIS
................................................................................................
51
4.1.1.
BACKGROUND
AND
IDEA
.................................................................................
51
4.1.2.
PROCEDURE
..................................................................................................
52
4.1.3.
MEANING
......................................................................................................
54
4.2.
FUNCTIONAL
MAGNETIC
RESONANCE
IMAGING
......................................................
56
4.2.1.
BOLD
RESPONSE
.........................................................................................
56
4.2.2. FUNCTIONAL
PLASTICITY
...................................................................................
58
5.
AIM
AND
UNDERLYING
HYPOTHESES
.......................................................................
59
EMPIRICAL
PART
..........................................................................................................
63
6.
STUDY
1
1
META-ANALYSIS
.....................................................................................
63
AGE-EFFECTS
OF
WORKING
MEMORY
TRAINING
ON
NEURAL
ACTIVATION
CHANGES
-
A
COMPARATIVE
META-ANALYSIS
.........................................................................................................
63
6.1.
INTRODUCTION
...................................................................................................
64
6.2.
MATERIAL
AND
METHOD
.....................................................................................
67
6.3.
RESULTS
...........................................................................................................
79
6.4.
DISCUSSION
....................................................................................................
85
7.
STUDY
2|
INTERVENTION
STUDY
.............................................................................
93
NEURAL
CORRELATES
OF
WORKING
MEMORY
TRAINING
IN
HEALTHY
OLDER
ADULTS
-
A
DOUBLE-BLIND
RANDOMIZED
CONTROLLED
TRIAL
......................................................................................
93
7.1.
INTRODUCTION
...................................................................................................
94
7.2.
MATERIAL
AND
METHOD
.....................................................................................
96
7.2.1.
PARTICIPANTS
................................................................................................
96
7.2.2.
TRAINING
......................................................................................................
97
10
7.2.3.
FMRI
TRANSFER
TASK
.....................................................................................
102
7.2.4.
STATISTICAL
ANALYSIS
....................................................................................
103
7.3.
RESULTS
..........................................................................................................
106
7.3.1.
BEHAVIORAL
DATA
.........................................................................................
106
7.3.2.
IMAGING
DATA
..............................................................................................
108
7.4.
DISCUSSION
....................................................................................................
114
8.
GENERAL
DISCUSSION
..........................................................................................
122
8.1.
IMPORTANCE
OF
THE
STUDIES
.............................................................................
122
8.2.
MAIN
DISCUSSION
...........................................................................................
123
8.3.
LIMITATIONS
.....................................................................................................
143
8.4.
OUTLOOK
.........................................................................................................
146
8.5.
CONCLUSION
....................................................................................................
154
REFERENCES
.............................................................................................................
156
LIST
OF
TABLES
..........................................................................................................
177
LIST
OF
FIGURES
.........................................................................................................
178
AUTHOR
INFORMATION
..................................................................................................
181
SUMMARY
................................................................................................................
185
ZUSAMMENFASSUNG
.................................................................................................
191
|
| adam_txt |
TABLE
OF
CONTENT
LIST
OF
ABBREVIATIONS
.
11
THEORETICAL
BACKGROUND
.
15
1.
COGNITIVE
AGING
.
17
2.
WORKING
MEMORY
.
25
2.1.
WORKING
MEMORY
MODELS
.
26
2.1.1.
MULTICOMPONENT
MODEL
OF
WORKING
MEMORY
BY
BADDELEY
AND
HITCH
.
27
2.1.2.
WORKING
MEMORY
MODEL
BY
ENGLE
.
34
2.1.3.
EMBEDDED-PROCESS
MODEL
BY
COWAN
.
35
2.2.
NEURAL
MECHANISMS
OF
WORKING
MEMORY
.
37
3.
WORKING
MEMORY
TRAINING:
CURRENT
STATE
OF
RESEARCH
.
43
4.
METHODS
.
51
4.1.
META-ANALYSIS
.
51
4.1.1.
BACKGROUND
AND
IDEA
.
51
4.1.2.
PROCEDURE
.
52
4.1.3.
MEANING
.
54
4.2.
FUNCTIONAL
MAGNETIC
RESONANCE
IMAGING
.
56
4.2.1.
BOLD
RESPONSE
.
56
4.2.2. FUNCTIONAL
PLASTICITY
.
58
5.
AIM
AND
UNDERLYING
HYPOTHESES
.
59
EMPIRICAL
PART
.
63
6.
STUDY
1
1
META-ANALYSIS
.
63
AGE-EFFECTS
OF
WORKING
MEMORY
TRAINING
ON
NEURAL
ACTIVATION
CHANGES
-
A
COMPARATIVE
META-ANALYSIS
.
63
6.1.
INTRODUCTION
.
64
6.2.
MATERIAL
AND
METHOD
.
67
6.3.
RESULTS
.
79
6.4.
DISCUSSION
.
85
7.
STUDY
2|
INTERVENTION
STUDY
.
93
NEURAL
CORRELATES
OF
WORKING
MEMORY
TRAINING
IN
HEALTHY
OLDER
ADULTS
-
A
DOUBLE-BLIND
RANDOMIZED
CONTROLLED
TRIAL
.
93
7.1.
INTRODUCTION
.
94
7.2.
MATERIAL
AND
METHOD
.
96
7.2.1.
PARTICIPANTS
.
96
7.2.2.
TRAINING
.
97
10
7.2.3.
FMRI
TRANSFER
TASK
.
102
7.2.4.
STATISTICAL
ANALYSIS
.
103
7.3.
RESULTS
.
106
7.3.1.
BEHAVIORAL
DATA
.
106
7.3.2.
IMAGING
DATA
.
108
7.4.
DISCUSSION
.
114
8.
GENERAL
DISCUSSION
.
122
8.1.
IMPORTANCE
OF
THE
STUDIES
.
122
8.2.
MAIN
DISCUSSION
.
123
8.3.
LIMITATIONS
.
143
8.4.
OUTLOOK
.
146
8.5.
CONCLUSION
.
154
REFERENCES
.
156
LIST
OF
TABLES
.
177
LIST
OF
FIGURES
.
178
AUTHOR
INFORMATION
.
181
SUMMARY
.
185
ZUSAMMENFASSUNG
.
191 |
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| author_GND | (DE-588)1205278494 |
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| spelling | Hudl, Nicole 1989- Verfasser (DE-588)1205278494 aut Neural correlates of working memory training fMRI analyses in healthy older adults vorgelegt von Master of Science Psychologin Nicole Hudl [Leipzig] 2020 1 CD-ROM (197 Seiten) Illustrationen txt rdacontent c rdamedia cd rdacarrier Dissertation Universität Leipzig 2019 (DE-588)4113937-9 Hochschulschrift gnd-content (DE-588)4139307-7 CD-ROM gnd-carrier DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=032328929&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Textdatei PDF |
| spellingShingle | Hudl, Nicole 1989- Neural correlates of working memory training fMRI analyses in healthy older adults |
| subject_GND | (DE-588)4113937-9 (DE-588)4139307-7 |
| title | Neural correlates of working memory training fMRI analyses in healthy older adults |
| title_auth | Neural correlates of working memory training fMRI analyses in healthy older adults |
| title_exact_search | Neural correlates of working memory training fMRI analyses in healthy older adults |
| title_exact_search_txtP | Neural correlates of working memory training fMRI analyses in healthy older adults |
| title_full | Neural correlates of working memory training fMRI analyses in healthy older adults vorgelegt von Master of Science Psychologin Nicole Hudl |
| title_fullStr | Neural correlates of working memory training fMRI analyses in healthy older adults vorgelegt von Master of Science Psychologin Nicole Hudl |
| title_full_unstemmed | Neural correlates of working memory training fMRI analyses in healthy older adults vorgelegt von Master of Science Psychologin Nicole Hudl |
| title_short | Neural correlates of working memory training |
| title_sort | neural correlates of working memory training fmri analyses in healthy older adults |
| title_sub | fMRI analyses in healthy older adults |
| topic_facet | Hochschulschrift CD-ROM |
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