A Case Approach to Perioperative Drug-Drug Interactions (Springer New York, 2015)
Part I. Introduction to Drug-Drug Interactions -- 1. Let's Start at the Very Beginning: Overcoming Fear and Gaining Mastery of Drug-Drug Interactions -- 2. Pharmacodynamic Interactions:  Core Concepts -- 3. Pharmacokinetic Interactions:  Core Concepts -- 4. A Brief Treatise On The Area Under The Curve -- Part II. Introduction to Drug-Drug Interactions:  Brief Review of CYP450 Enzymes, UGTs, and Transporters -- 5. CYP2D6:  Where It All Began -- 6. CYP2E1:  The Anesthesia Enzyme -- 7. CYP3A4:  The Workhorse -- 8. CYP1A2:  The Switch-hitter -- 9. CYP2B:   2B or Not 2B?- 10. CYP2C9:  The Support Crew I -- 11. CYP2C19:   The Support Crew II -- 12. UGTs:  Conjugating Cousins -- 13. The Cytochrome P450 System In Disease States-A Brief Review -- PART III. Drug-Drug Interactions:  Paradigms and Core Concepts -- 14. P-glycoprotein and OATP Transporters -- 15. The  "Fatal" Forty -- 16. The Six Patterns of Pharmacokinetic Drug-Drug Interactions --
- 17. The Problem with the Drug-Drug Interaction Software: A Procrustean Dilemma -- 18. Pharmacogenomics -- 19. The Pharmacoepidemiology of Drug Interactions: Why and How They Are Important -- 20. The Lawyers Can Read, Too:  Case Presentations from the Courtroom -- Part IV. Drug-Drug Interactions Involving Inhalational Anesthetic Agents -- 21. Introduction -- 22. That Sums It Up -- 23. 1+1+1+1=? -- 24. A Delayed Surgeon Is A "Dismayed" Surgeon? -- 25. Relax, It's Only Gentamicin -- 26. Jaundice After Surgery -- 27. Everybody Clear? -- 28. The Hemodynamic Hole -- 29. Alpha-2 To The Rescue But Beware Bradycardia -- 30. Hot Stuff! -- Part V. Drug-Drug Interactions Involving Intravenous Anesthetic Agents -- 31. Introduction -- 32. How to Successfully Occlude an Intravenous Line -- 33. A Curious Cause of Seizures -- 34. Magnesium Mama And The Mad Dad -- 35. Dexy's Midnight Spinal -- Part VI. Drug-Drug Interactions Involving Local Anesthetics -- 36. Introduction -- 37. Comfortably Numb --
- 38. Naturally Occurring And Nasty -- 39. LOL-LOL:  Little Old Lady-Lots of Lido -- 40. The Spinal Countdown -- 41.  Are Drug-Drug Interactions The Smoking Guns of Local Anesthetic Toxicity?  Smoking Gun I -- 42. Are Drug-Drug Interactions The Smoking Guns of Local Anesthetic Toxicity?  Smoking Gun II -- 43. A Perfect Storm? -- 44. Shake Rattle and Roll -- 45. Hello, We Have A Patient With Acute Delirium and We Need An Urgent Psych Consult -- 46. Fatal Pain Relief -- 47. Lipid Lifesaver -- Part VII. Drug-Drug Interactions Involving Opioids -- 48. Introduction -- 49. No 'Subs'titute for Sobriety -- 50. A Needle And The Damage Done -- 51. Dad's Not Having Much Pain -- 52. Royal Flush -- 53. The Worry That's Always With Us:  Afternoon Nap -- 54. The Bawling Baby -- 55. Sleeping Beauty -- 56. Codeine Can't Do It -- 57. A Shuddering Interaction -- 58. Double Indemnity -- 59. Breaking the Codeine -- 60. The Ultimate Ultram Primer I:  My Mood Is Better, But Boy Do I Hurt! --
- 61. The Ultimate Ultram Primer II: I "Haight" Narcotics But I Hate Seizures Worse -- 62. The Ultimate Ultram Primer III:  Tremor-dol Trigger in Serotonin Syndrome -- 63. Too Much of A Good Thing -- Part VIII. Drug-Drug Interactions Involving Non-opioid Pain Medications -- 64. Introduction -- 65. Pining For Pete In The Pain Clinic -- 66. You Do Not Look Well Today, Mon Ami -- 67. My Headache is Gone, But My Leg Now Hurts -- 68. Special 'K'ase -- 69. Not Manic About NSAIDs -- 70. Keep It Capped! -- 71. The ACE Is Not Always High -- 72. When The Smoke Clears, Relaxation Disappears -- 73. Befuddled by Aspirin -- 74. You Can't Trick Us! -- Part IX. Drug-Drug Interactions Involving Benzodiazepines and Other Sedatives -- 75. Introduction -- 76. The Worry That's Always With Us:  Now I'm Depressed -- 77. The Worry That's Always With Us: Tragic But Not Rare -- 78. Lack of Sedation -- 79. A Cold Isn't Going to Slow Me Down -- 80. Her Patients Never Wake Up On Time --
- 81. When Enough Is Now Too Much -- 82. The Distressed Daughter -- 83. Check Check and Double Check -- 84. Doggone It-The Case is Cancelled -- 85. Noct' Out -- 86. Predisposed to Doze -- 87. Synergistic Sedation -- Part X. Drug-Drug Interactions Involving Neuromuscular Blockade Agents -- 88. Introduction -- 89. Blocked Again -- 90. Irreversibility Sux -- 91. Keep An "Ion" The Twitches -- 92. A Reversal of Misfortune -- 93. Stop Moving -- 94. There's Just Not Enough Roc In The World -- 95. Slow Sux I:  A Lengthy Wake-Up Period After Electroconvulsive Therapy -- 96. Slow Sux II:  I Remember Reviewing This For The Boards -- 97. Slow Sux III:  Where Did the Twitches Go? -- 98. Weakened All Weekend -- 99. The Patient Who Could Not Raise Her Head -- 100. An Unexpected Wait -- 101. Diabolical Cough Syrup -- Part XI. Drug-Drug Interactions Involving Antibiotics and Antifungals -- 102. Introduction -- 103. Full Stop -- 104. Flummoxed by the FLOX -- 105. Tales of Terror --