Impedimetric biosensors for medical applications: current progress and challenges

In this monograph, the authors discuss the current progress in the medical application of impedimetric biosensors, along with the key challenges in the field. First, a general overview of biosensor development, structure and function is presented, followed by a detailed discussion of impedimetric bi...

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Bibliographic Details
Main Authors: Rushworth, Jo V. (Author), Hirst, Natalie A. (Author), Goode, Jack A. (Author), Pike, Douglas J. (Author), Ahmed, Asif (Author), Millner, Paul A. (Author)
Format: Electronic eBook
Language:English
Published: New York, New York American Society Of Mechanical Engineers [2013]
Series:Biomedical & nanomedical technologies
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Online Access:Volltext
Summary:In this monograph, the authors discuss the current progress in the medical application of impedimetric biosensors, along with the key challenges in the field. First, a general overview of biosensor development, structure and function is presented, followed by a detailed discussion of impedimetric biosensors and the principles of electrochemical impedance spectroscopy. Next, the current state-of-the art in terms of the science and technology underpinning impedance-based biosensors is reviewed in detail. The layer- by-layer construction of impedimetric sensors is described, including the design of electrodes, their nano-modification, transducer surface functionalisation and the attachment of different bioreceptors. The current challenges of translating lab-based biosensor platforms into commercially-available devices that function with real patient samples at the POC are presented; this includes a consideration of systems integration, microfluidics and biosensor regeneration. The final section of this monograph describes case studies of successful impedance-based biosensors for the detection of a range of analytes from small molecules up to whole microorganisms. Finally, the authors put forward future perspectives for the clinical applications of impedimetric biosensors. Read less
Item Description:Includes bibliographical references (pages 57-70)
Introduction and scope -- Biosensors -- Electrochemical impedance spectroscopy -- Fabrication of impedimetric biosensors -- Commercializing impedimetric biosensors: from laboratory to field -- Case studies of impedimetric biosensors for medical applications. - System requirements: Adobe Acrobat Reader. - Mode of access: World Wide Web
Physical Description:1 Online-Ressource (70 Seiten) illustrations

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