Selling Science: Polio and the Promise of Gamma Globulin
Today, when many parents seem reluctant to have their children vaccinated, even with long proven medications, the Salk vaccine trial, which enrolled millions of healthy children to test an unproven medical intervention, seems nothing short of astonishing. In Selling Science, medical historian Stephe...
Gespeichert in:
1. Verfasser: | |
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Format: | Elektronisch E-Book |
Sprache: | English |
Veröffentlicht: |
New Brunswick, NJ
Rutgers University Press
[2016]
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Schriftenreihe: | Critical Issues in Health and Medicine
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Schlagworte: | |
Online-Zugang: | DE-1046 DE-859 DE-860 DE-739 DE-1043 DE-858 URL des Erstveröffentlichers |
Zusammenfassung: | Today, when many parents seem reluctant to have their children vaccinated, even with long proven medications, the Salk vaccine trial, which enrolled millions of healthy children to test an unproven medical intervention, seems nothing short of astonishing. In Selling Science, medical historian Stephen E. Mawdsley recounts the untold story of the first large clinical trial to control polio using healthy children—55,000 healthy children—revealing how this long-forgotten incident cleared the path for Salk’s later trial. Mawdsley describes how, in the early 1950s, Dr. William Hammon and the National Foundation for Infantile Paralysis launched a pioneering medical experiment on a previously untried scale. Conducted on over 55,000 healthy children in Texas, Utah, Iowa, and Nebraska, this landmark study assessed the safety and effectiveness of a blood component, gamma globulin, to prevent paralytic polio. The value of the proposed experiment was questioned by many prominent health professionals as it harbored potential health risks, but as Mawdsley points out, compromise and coercion moved it forward. And though the trial returned dubious results, it was presented to the public as a triumph and used to justify a federally sanctioned mass immunization study on thousands of families between 1953 and 1954. Indeed, the concept, conduct, and outcome of the GG study were sold to health professionals, medical researchers, and the public at each stage. At a time when most Americans trusted scientists, their mutual encounter under the auspices of conquering disease was shaped by politics, marketing, and at times, deception. Drawing on oral history interviews, medical journals, newspapers, meeting minutes, and private institutional records, Selling Science sheds light on the ethics of scientific conduct, and on the power of marketing to shape public opinion about medical experimentation |
Beschreibung: | Description based on online resource; title from PDF title page (publisher's Web site, viewed 22. Okt 2019) |
Beschreibung: | 1 online resource 14 photographs, 3 maps, 4 figures |
ISBN: | 9780813574417 |
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spelling | Mawdsley, Stephen E. Verfasser aut Selling Science Polio and the Promise of Gamma Globulin Stephen E. Mawdsley New Brunswick, NJ Rutgers University Press [2016] © 2016 1 online resource 14 photographs, 3 maps, 4 figures txt rdacontent c rdamedia cr rdacarrier Critical Issues in Health and Medicine Description based on online resource; title from PDF title page (publisher's Web site, viewed 22. Okt 2019) Today, when many parents seem reluctant to have their children vaccinated, even with long proven medications, the Salk vaccine trial, which enrolled millions of healthy children to test an unproven medical intervention, seems nothing short of astonishing. In Selling Science, medical historian Stephen E. Mawdsley recounts the untold story of the first large clinical trial to control polio using healthy children—55,000 healthy children—revealing how this long-forgotten incident cleared the path for Salk’s later trial. Mawdsley describes how, in the early 1950s, Dr. William Hammon and the National Foundation for Infantile Paralysis launched a pioneering medical experiment on a previously untried scale. Conducted on over 55,000 healthy children in Texas, Utah, Iowa, and Nebraska, this landmark study assessed the safety and effectiveness of a blood component, gamma globulin, to prevent paralytic polio. The value of the proposed experiment was questioned by many prominent health professionals as it harbored potential health risks, but as Mawdsley points out, compromise and coercion moved it forward. And though the trial returned dubious results, it was presented to the public as a triumph and used to justify a federally sanctioned mass immunization study on thousands of families between 1953 and 1954. Indeed, the concept, conduct, and outcome of the GG study were sold to health professionals, medical researchers, and the public at each stage. At a time when most Americans trusted scientists, their mutual encounter under the auspices of conquering disease was shaped by politics, marketing, and at times, deception. Drawing on oral history interviews, medical journals, newspapers, meeting minutes, and private institutional records, Selling Science sheds light on the ethics of scientific conduct, and on the power of marketing to shape public opinion about medical experimentation In English Geschichte 1951-1954 gnd rswk-swf SCIENCE / General bisacsh Children Diseases United States Prevention History 20th century Clinical trials United States History 20th century Gamma globulins Research United States History 20th century Poliomyelitis Research United States History 20th century Poliomyelitis United States Prevention History 20th century Science Economic aspects History 20th century Science Social aspects History 20th century Klinisches Experiment (DE-588)4164223-5 gnd rswk-swf Immunglobuline (DE-588)4026626-6 gnd rswk-swf Impfung (DE-588)4026656-4 gnd rswk-swf Kinderlähmung (DE-588)4163840-2 gnd rswk-swf Kinderlähmung (DE-588)4163840-2 s Immunglobuline (DE-588)4026626-6 s Impfung (DE-588)4026656-4 s Klinisches Experiment (DE-588)4164223-5 s Geschichte 1951-1954 z 1\p DE-604 https://www.degruyter.com/isbn/9780813574417 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
spellingShingle | Mawdsley, Stephen E. Selling Science Polio and the Promise of Gamma Globulin SCIENCE / General bisacsh Children Diseases United States Prevention History 20th century Clinical trials United States History 20th century Gamma globulins Research United States History 20th century Poliomyelitis Research United States History 20th century Poliomyelitis United States Prevention History 20th century Science Economic aspects History 20th century Science Social aspects History 20th century Klinisches Experiment (DE-588)4164223-5 gnd Immunglobuline (DE-588)4026626-6 gnd Impfung (DE-588)4026656-4 gnd Kinderlähmung (DE-588)4163840-2 gnd |
subject_GND | (DE-588)4164223-5 (DE-588)4026626-6 (DE-588)4026656-4 (DE-588)4163840-2 |
title | Selling Science Polio and the Promise of Gamma Globulin |
title_auth | Selling Science Polio and the Promise of Gamma Globulin |
title_exact_search | Selling Science Polio and the Promise of Gamma Globulin |
title_full | Selling Science Polio and the Promise of Gamma Globulin Stephen E. Mawdsley |
title_fullStr | Selling Science Polio and the Promise of Gamma Globulin Stephen E. Mawdsley |
title_full_unstemmed | Selling Science Polio and the Promise of Gamma Globulin Stephen E. Mawdsley |
title_short | Selling Science |
title_sort | selling science polio and the promise of gamma globulin |
title_sub | Polio and the Promise of Gamma Globulin |
topic | SCIENCE / General bisacsh Children Diseases United States Prevention History 20th century Clinical trials United States History 20th century Gamma globulins Research United States History 20th century Poliomyelitis Research United States History 20th century Poliomyelitis United States Prevention History 20th century Science Economic aspects History 20th century Science Social aspects History 20th century Klinisches Experiment (DE-588)4164223-5 gnd Immunglobuline (DE-588)4026626-6 gnd Impfung (DE-588)4026656-4 gnd Kinderlähmung (DE-588)4163840-2 gnd |
topic_facet | SCIENCE / General Children Diseases United States Prevention History 20th century Clinical trials United States History 20th century Gamma globulins Research United States History 20th century Poliomyelitis Research United States History 20th century Poliomyelitis United States Prevention History 20th century Science Economic aspects History 20th century Science Social aspects History 20th century Klinisches Experiment Immunglobuline Impfung Kinderlähmung |
url | https://www.degruyter.com/isbn/9780813574417 |
work_keys_str_mv | AT mawdsleystephene sellingsciencepolioandthepromiseofgammaglobulin |