The Interface Between Innate and Acquired Immunity:
All multicellular organisms may possess innate immunity mediated by defense mechanisms with which the organism is born. In recent years much has been learned about the diversity of innate immune mechanisms. A large array of naturally produced antimicrobial peptides has been de fined. A variety of c...
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Berlin, Heidelberg
Springer Berlin Heidelberg
2002
|
| Schriftenreihe: | Current Topics in Microbiology and Immunology
266 |
| Schlagworte: | |
| Online-Zugang: | UBR01 URL des Erstveröffentlichers |
| Zusammenfassung: | All multicellular organisms may possess innate immunity mediated by defense mechanisms with which the organism is born. In recent years much has been learned about the diversity of innate immune mechanisms. A large array of naturally produced antimicrobial peptides has been de fined. A variety of cell surface receptors that recognize common patterns displayed by infectious organisms have been identified along with the intracellular pathways that these receptors use to activate cellular defense functions. Cell surface receptors on natural killer (NK) cells have been shown to sense microbial invasion in neighboring cells, thereby setting into motion their elimination by cy totoxic mechanisms. Other receptors have been found to facilitate phagocytosis and intracellular killing of microbes by phagocytic cells. These and other natural defense mechanisms have traditionally been viewed as the first line of body defense in vertebrate species that also possess the capacity for acquired or adaptive immunity. Sharks and all of the other jawed vertebrates generate large repertoires of T and B lymphocyte clones that display different antigen specific receptors in the form ofT cell receptors (TCR) and immunoglobulins (Ig) that allow them to recognize and respond to antigens in collaboration with antigen-present ing cells. Memory T and B cells are then generated to allow faster and heightened cellular and humoral immune re sponses on secondary antigen encounter. In recent years it has also become obvious that innate immune responses can directly influence adaptive immune responses in ways that will enhance body defense |
| Beschreibung: | 1 Online-Ressource (XIII, 118 p) |
| ISBN: | 9783662047002 |
| DOI: | 10.1007/978-3-662-04700-2 |
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| 520 | |a All multicellular organisms may possess innate immunity mediated by defense mechanisms with which the organism is born. In recent years much has been learned about the diversity of innate immune mechanisms. A large array of naturally produced antimicrobial peptides has been de fined. A variety of cell surface receptors that recognize common patterns displayed by infectious organisms have been identified along with the intracellular pathways that these receptors use to activate cellular defense functions. Cell surface receptors on natural killer (NK) cells have been shown to sense microbial invasion in neighboring cells, thereby setting into motion their elimination by cy totoxic mechanisms. Other receptors have been found to facilitate phagocytosis and intracellular killing of microbes by phagocytic cells. These and other natural defense mechanisms have traditionally been viewed as the first line of body defense in vertebrate species that also possess the capacity for acquired or adaptive immunity. Sharks and all of the other jawed vertebrates generate large repertoires of T and B lymphocyte clones that display different antigen specific receptors in the form ofT cell receptors (TCR) and immunoglobulins (Ig) that allow them to recognize and respond to antigens in collaboration with antigen-present ing cells. Memory T and B cells are then generated to allow faster and heightened cellular and humoral immune re sponses on secondary antigen encounter. In recent years it has also become obvious that innate immune responses can directly influence adaptive immune responses in ways that will enhance body defense | ||
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| discipline | Biologie |
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| spelling | The Interface Between Innate and Acquired Immunity edited by Max D. Cooper, Hilary Koprowski Berlin, Heidelberg Springer Berlin Heidelberg 2002 1 Online-Ressource (XIII, 118 p) txt rdacontent c rdamedia cr rdacarrier Current Topics in Microbiology and Immunology 266 All multicellular organisms may possess innate immunity mediated by defense mechanisms with which the organism is born. In recent years much has been learned about the diversity of innate immune mechanisms. A large array of naturally produced antimicrobial peptides has been de fined. A variety of cell surface receptors that recognize common patterns displayed by infectious organisms have been identified along with the intracellular pathways that these receptors use to activate cellular defense functions. Cell surface receptors on natural killer (NK) cells have been shown to sense microbial invasion in neighboring cells, thereby setting into motion their elimination by cy totoxic mechanisms. Other receptors have been found to facilitate phagocytosis and intracellular killing of microbes by phagocytic cells. These and other natural defense mechanisms have traditionally been viewed as the first line of body defense in vertebrate species that also possess the capacity for acquired or adaptive immunity. Sharks and all of the other jawed vertebrates generate large repertoires of T and B lymphocyte clones that display different antigen specific receptors in the form ofT cell receptors (TCR) and immunoglobulins (Ig) that allow them to recognize and respond to antigens in collaboration with antigen-present ing cells. Memory T and B cells are then generated to allow faster and heightened cellular and humoral immune re sponses on secondary antigen encounter. In recent years it has also become obvious that innate immune responses can directly influence adaptive immune responses in ways that will enhance body defense Microbiology Immunology Immunität Medizin (DE-588)4120476-1 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Immunität Medizin (DE-588)4120476-1 s DE-604 Cooper, Max D. edt Koprowski, Hilary edt Erscheint auch als Druck-Ausgabe 9783642076824 Erscheint auch als Druck-Ausgabe 9783662047019 Erscheint auch als Druck-Ausgabe 9783540428947 https://doi.org/10.1007/978-3-662-04700-2 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | The Interface Between Innate and Acquired Immunity Microbiology Immunology Immunität Medizin (DE-588)4120476-1 gnd |
| subject_GND | (DE-588)4120476-1 (DE-588)4143413-4 |
| title | The Interface Between Innate and Acquired Immunity |
| title_auth | The Interface Between Innate and Acquired Immunity |
| title_exact_search | The Interface Between Innate and Acquired Immunity |
| title_full | The Interface Between Innate and Acquired Immunity edited by Max D. Cooper, Hilary Koprowski |
| title_fullStr | The Interface Between Innate and Acquired Immunity edited by Max D. Cooper, Hilary Koprowski |
| title_full_unstemmed | The Interface Between Innate and Acquired Immunity edited by Max D. Cooper, Hilary Koprowski |
| title_short | The Interface Between Innate and Acquired Immunity |
| title_sort | the interface between innate and acquired immunity |
| topic | Microbiology Immunology Immunität Medizin (DE-588)4120476-1 gnd |
| topic_facet | Microbiology Immunology Immunität Medizin Aufsatzsammlung |
| url | https://doi.org/10.1007/978-3-662-04700-2 |
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