Cancer Metastasis — Related Genes:
Being diagnosed with cancer is devastating. But when the cancer cells have to spread to form secondary colonies, the prognosis for the patient is worse. If meaningful improvements in survival are to occur, then control of metastasis will be a foundation. Relatively little is known about the control...
Saved in:
| Other Authors: | |
|---|---|
| Format: | Electronic eBook |
| Language: | English |
| Published: |
Dordrecht
Springer Netherlands
2002
|
| Series: | Cancer Metastasis - Biology and Treatment
3 |
| Subjects: | |
| Online Access: | UBR01 Volltext |
| Summary: | Being diagnosed with cancer is devastating. But when the cancer cells have to spread to form secondary colonies, the prognosis for the patient is worse. If meaningful improvements in survival are to occur, then control of metastasis will be a foundation. Relatively little is known about the control of the metastatic process at the molecular level. This volume begins to explore our current knowledge regarding the underlying molecular and biochemical mechanisms controlling the metastatic phenotype. While all of the authors attempted to put their findings into a context for translation to the clinical situation, the state-of-the-art does not fully allow this. Nonetheless, we write these summaries of our work as an early effort toward that end. I am grateful to all of the authors who have contributed generously of their time and energies to make this volume a reality. To metastasize, neoplastic cells dissociate from the primary tumor, enter a circulatory compartment (typically lymphatics or blood vasculature), survive transport, arrest, exit the circulation and finally proliferate at a discontinuous site in response to local growth factors. Unless cells accomplish every step of the metastatic cascade, metastases cannot develop. The process is highly inefficient, i. e. , |
| Physical Description: | 1 Online-Ressource (XIV, 270 p) |
| ISBN: | 9780306478215 |
| DOI: | 10.1007/0-306-47821-8 |
Staff View
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| 520 | |a Being diagnosed with cancer is devastating. But when the cancer cells have to spread to form secondary colonies, the prognosis for the patient is worse. If meaningful improvements in survival are to occur, then control of metastasis will be a foundation. Relatively little is known about the control of the metastatic process at the molecular level. This volume begins to explore our current knowledge regarding the underlying molecular and biochemical mechanisms controlling the metastatic phenotype. While all of the authors attempted to put their findings into a context for translation to the clinical situation, the state-of-the-art does not fully allow this. Nonetheless, we write these summaries of our work as an early effort toward that end. I am grateful to all of the authors who have contributed generously of their time and energies to make this volume a reality. To metastasize, neoplastic cells dissociate from the primary tumor, enter a circulatory compartment (typically lymphatics or blood vasculature), survive transport, arrest, exit the circulation and finally proliferate at a discontinuous site in response to local growth factors. Unless cells accomplish every step of the metastatic cascade, metastases cannot develop. The process is highly inefficient, i. e. , | ||
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| illustrated | Not Illustrated |
| indexdate | 2024-07-10T08:36:35Z |
| institution | BVB |
| isbn | 9780306478215 |
| language | English |
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| spelling | Cancer Metastasis — Related Genes edited by Danny R. Welch Dordrecht Springer Netherlands 2002 1 Online-Ressource (XIV, 270 p) txt rdacontent c rdamedia cr rdacarrier Cancer Metastasis - Biology and Treatment 3 Being diagnosed with cancer is devastating. But when the cancer cells have to spread to form secondary colonies, the prognosis for the patient is worse. If meaningful improvements in survival are to occur, then control of metastasis will be a foundation. Relatively little is known about the control of the metastatic process at the molecular level. This volume begins to explore our current knowledge regarding the underlying molecular and biochemical mechanisms controlling the metastatic phenotype. While all of the authors attempted to put their findings into a context for translation to the clinical situation, the state-of-the-art does not fully allow this. Nonetheless, we write these summaries of our work as an early effort toward that end. I am grateful to all of the authors who have contributed generously of their time and energies to make this volume a reality. To metastasize, neoplastic cells dissociate from the primary tumor, enter a circulatory compartment (typically lymphatics or blood vasculature), survive transport, arrest, exit the circulation and finally proliferate at a discontinuous site in response to local growth factors. Unless cells accomplish every step of the metastatic cascade, metastases cannot develop. The process is highly inefficient, i. e. , Oncology Human Genetics Life Sciences, general Pathology Epidemiology Oncology Human genetics Life sciences Suppressorgen (DE-588)4278851-1 gnd rswk-swf Metastase (DE-588)4125915-4 gnd rswk-swf Metastase (DE-588)4125915-4 s Suppressorgen (DE-588)4278851-1 s DE-604 Welch, Danny R. edt Erscheint auch als Druck-Ausgabe 9789401739221 Erscheint auch als Druck-Ausgabe 9781402005220 Erscheint auch als Druck-Ausgabe 9789401739214 https://doi.org/10.1007/0-306-47821-8 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Cancer Metastasis — Related Genes Oncology Human Genetics Life Sciences, general Pathology Epidemiology Oncology Human genetics Life sciences Suppressorgen (DE-588)4278851-1 gnd Metastase (DE-588)4125915-4 gnd |
| subject_GND | (DE-588)4278851-1 (DE-588)4125915-4 |
| title | Cancer Metastasis — Related Genes |
| title_auth | Cancer Metastasis — Related Genes |
| title_exact_search | Cancer Metastasis — Related Genes |
| title_full | Cancer Metastasis — Related Genes edited by Danny R. Welch |
| title_fullStr | Cancer Metastasis — Related Genes edited by Danny R. Welch |
| title_full_unstemmed | Cancer Metastasis — Related Genes edited by Danny R. Welch |
| title_short | Cancer Metastasis — Related Genes |
| title_sort | cancer metastasis related genes |
| topic | Oncology Human Genetics Life Sciences, general Pathology Epidemiology Oncology Human genetics Life sciences Suppressorgen (DE-588)4278851-1 gnd Metastase (DE-588)4125915-4 gnd |
| topic_facet | Oncology Human Genetics Life Sciences, general Pathology Epidemiology Oncology Human genetics Life sciences Suppressorgen Metastase |
| url | https://doi.org/10.1007/0-306-47821-8 |
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