Silencing, Heterochromatin and DNA Double Strand Break Repair:
The field of DNA repair is vast and advancing rapidly. Recent investigations have begun to focus on the involvement of chromatin in the repair of broken DNA. Although I have no doubt that many breakthroughs in our understanding of chromatin, chromatin regulation, and DNA repair lie in our future, pr...
Gespeichert in:
| 1. Verfasser: | |
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| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Boston, MA
Springer US
2001
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| Schlagworte: | |
| Online-Zugang: | UBR01 Volltext |
| Zusammenfassung: | The field of DNA repair is vast and advancing rapidly. Recent investigations have begun to focus on the involvement of chromatin in the repair of broken DNA. Although I have no doubt that many breakthroughs in our understanding of chromatin, chromatin regulation, and DNA repair lie in our future, presently this is a new line in inquiry. As such there are many, many unanswered questions. Indeed, most of the correct questions have probably not even been asked yet. Here I have attempted to present a review of some of the current body of knowledge that may prove relevant to understanding the role of chromatin in DNA repair. Because the volume of research, and the relevant findings, come from a staggering array of labs, systems, and ideas I have focused primarily on findings developed from the study of the budding yeast Saccharomyces cerevisiae. Unfortunately, this means that I have left out a great deal of information. It is my hope, however, that the information I do detail, particularly in Chapter 1, will give a flavor for the scope of the problem and perhaps highlight some of the interesting directions this field is taking, or may one day take. I would also point out that the primary research that is presented herein is not in any way meant to represent the comprehensive scope of research being performed. To understand DNA repair will require investigation from innumerable labs, performed by innumerable researchers, moving in unexpected directions |
| Beschreibung: | 1 Online-Ressource (XI, 122 p) |
| ISBN: | 9781461543619 |
| DOI: | 10.1007/978-1-4615-4361-9 |
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| 520 | |a The field of DNA repair is vast and advancing rapidly. Recent investigations have begun to focus on the involvement of chromatin in the repair of broken DNA. Although I have no doubt that many breakthroughs in our understanding of chromatin, chromatin regulation, and DNA repair lie in our future, presently this is a new line in inquiry. As such there are many, many unanswered questions. Indeed, most of the correct questions have probably not even been asked yet. Here I have attempted to present a review of some of the current body of knowledge that may prove relevant to understanding the role of chromatin in DNA repair. Because the volume of research, and the relevant findings, come from a staggering array of labs, systems, and ideas I have focused primarily on findings developed from the study of the budding yeast Saccharomyces cerevisiae. Unfortunately, this means that I have left out a great deal of information. It is my hope, however, that the information I do detail, particularly in Chapter 1, will give a flavor for the scope of the problem and perhaps highlight some of the interesting directions this field is taking, or may one day take. I would also point out that the primary research that is presented herein is not in any way meant to represent the comprehensive scope of research being performed. To understand DNA repair will require investigation from innumerable labs, performed by innumerable researchers, moving in unexpected directions | ||
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| id | DE-604.BV046149054 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T08:36:35Z |
| institution | BVB |
| isbn | 9781461543619 |
| language | English |
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| spelling | Mills, Kevin D. Verfasser aut Silencing, Heterochromatin and DNA Double Strand Break Repair by Kevin D. Mills Boston, MA Springer US 2001 1 Online-Ressource (XI, 122 p) txt rdacontent c rdamedia cr rdacarrier The field of DNA repair is vast and advancing rapidly. Recent investigations have begun to focus on the involvement of chromatin in the repair of broken DNA. Although I have no doubt that many breakthroughs in our understanding of chromatin, chromatin regulation, and DNA repair lie in our future, presently this is a new line in inquiry. As such there are many, many unanswered questions. Indeed, most of the correct questions have probably not even been asked yet. Here I have attempted to present a review of some of the current body of knowledge that may prove relevant to understanding the role of chromatin in DNA repair. Because the volume of research, and the relevant findings, come from a staggering array of labs, systems, and ideas I have focused primarily on findings developed from the study of the budding yeast Saccharomyces cerevisiae. Unfortunately, this means that I have left out a great deal of information. It is my hope, however, that the information I do detail, particularly in Chapter 1, will give a flavor for the scope of the problem and perhaps highlight some of the interesting directions this field is taking, or may one day take. I would also point out that the primary research that is presented herein is not in any way meant to represent the comprehensive scope of research being performed. To understand DNA repair will require investigation from innumerable labs, performed by innumerable researchers, moving in unexpected directions Animal Anatomy / Morphology / Histology Biological Microscopy Human Genetics Developmental Biology Oncology Morphology (Animals) Microscopy Human genetics Developmental biology Oncology Erscheint auch als Druck-Ausgabe 9781461369608 Erscheint auch als Druck-Ausgabe 9780792379829 Erscheint auch als Druck-Ausgabe 9781461543626 https://doi.org/10.1007/978-1-4615-4361-9 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Mills, Kevin D. Silencing, Heterochromatin and DNA Double Strand Break Repair Animal Anatomy / Morphology / Histology Biological Microscopy Human Genetics Developmental Biology Oncology Morphology (Animals) Microscopy Human genetics Developmental biology Oncology |
| title | Silencing, Heterochromatin and DNA Double Strand Break Repair |
| title_auth | Silencing, Heterochromatin and DNA Double Strand Break Repair |
| title_exact_search | Silencing, Heterochromatin and DNA Double Strand Break Repair |
| title_full | Silencing, Heterochromatin and DNA Double Strand Break Repair by Kevin D. Mills |
| title_fullStr | Silencing, Heterochromatin and DNA Double Strand Break Repair by Kevin D. Mills |
| title_full_unstemmed | Silencing, Heterochromatin and DNA Double Strand Break Repair by Kevin D. Mills |
| title_short | Silencing, Heterochromatin and DNA Double Strand Break Repair |
| title_sort | silencing heterochromatin and dna double strand break repair |
| topic | Animal Anatomy / Morphology / Histology Biological Microscopy Human Genetics Developmental Biology Oncology Morphology (Animals) Microscopy Human genetics Developmental biology Oncology |
| topic_facet | Animal Anatomy / Morphology / Histology Biological Microscopy Human Genetics Developmental Biology Oncology Morphology (Animals) Microscopy Human genetics Developmental biology Oncology |
| url | https://doi.org/10.1007/978-1-4615-4361-9 |
| work_keys_str_mv | AT millskevind silencingheterochromatinanddnadoublestrandbreakrepair |