Signalling from Internalized Growth Factor Receptors:
This book reviews knowledge on the interconnection of signal transduction and endocytosis/intracellular trafficking. The chapters cover knowledge obtained by using different model systems. The first chapter deals with Receptor Tyrosin Kinases (RTKs) with emphasis on the Epidermal Growth Factor Recep...
Saved in:
| Other Authors: | |
|---|---|
| Format: | Electronic eBook |
| Language: | English |
| Published: |
Berlin, Heidelberg
Springer Berlin Heidelberg
2004
|
| Series: | Current Topics in Microbiology and Immunology
286 |
| Subjects: | |
| Online Access: | UBR01 Volltext |
| Summary: | This book reviews knowledge on the interconnection of signal transduction and endocytosis/intracellular trafficking. The chapters cover knowledge obtained by using different model systems. The first chapter deals with Receptor Tyrosin Kinases (RTKs) with emphasis on the Epidermal Growth Factor Receptor (EGF receptor) and the Platelet Derived Growth Factor Receptor (PDGF receptor). The second chapter deals with the RTK c-Met and with how this RTK becomes carcinogenic. The third chapter reviews recent understanding on the mechanisms of action of the numerous fibroblast growth factors and their receptors. In the fourth chapter we learn about the trafficking of and signalling from the Growth Hormone Receptor and how this receptor is controlled by ubiquitination. The fifth chapter is devoted to the Interleukin II receptor, essential for activation of T cells. Links between ubiquitination, signalling, endocytosis, and sorting are reviewed. The last chapter discusses current views on how monoubiquitination controls both signalling and trafficking and thereby the final outcome of receptor activation |
| Physical Description: | 1 Online-Ressource (IX, 190 p. 31 illus., 4 illus. in color) |
| ISBN: | 9783540694946 |
| DOI: | 10.1007/978-3-540-69494-6 |
Staff View
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| indexdate | 2024-07-10T08:36:34Z |
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| isbn | 9783540694946 |
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| spelling | Signalling from Internalized Growth Factor Receptors edited by Inger Helene Madshus Berlin, Heidelberg Springer Berlin Heidelberg 2004 1 Online-Ressource (IX, 190 p. 31 illus., 4 illus. in color) txt rdacontent c rdamedia cr rdacarrier Current Topics in Microbiology and Immunology 286 This book reviews knowledge on the interconnection of signal transduction and endocytosis/intracellular trafficking. The chapters cover knowledge obtained by using different model systems. The first chapter deals with Receptor Tyrosin Kinases (RTKs) with emphasis on the Epidermal Growth Factor Receptor (EGF receptor) and the Platelet Derived Growth Factor Receptor (PDGF receptor). The second chapter deals with the RTK c-Met and with how this RTK becomes carcinogenic. The third chapter reviews recent understanding on the mechanisms of action of the numerous fibroblast growth factors and their receptors. In the fourth chapter we learn about the trafficking of and signalling from the Growth Hormone Receptor and how this receptor is controlled by ubiquitination. The fifth chapter is devoted to the Interleukin II receptor, essential for activation of T cells. Links between ubiquitination, signalling, endocytosis, and sorting are reviewed. The last chapter discusses current views on how monoubiquitination controls both signalling and trafficking and thereby the final outcome of receptor activation Medical Microbiology Microbiology Signaltransduktion (DE-588)4318717-1 gnd rswk-swf Intrazellulärer Transport (DE-588)4313701-5 gnd rswk-swf Wachstumsfaktor (DE-588)4188802-9 gnd rswk-swf Rezeptor (DE-588)4049722-7 gnd rswk-swf Endocytose (DE-588)4152168-7 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Wachstumsfaktor (DE-588)4188802-9 s Rezeptor (DE-588)4049722-7 s Signaltransduktion (DE-588)4318717-1 s Endocytose (DE-588)4152168-7 s Intrazellulärer Transport (DE-588)4313701-5 s DE-604 Madshus, Inger Helene edt Erscheint auch als Druck-Ausgabe 9783642059124 Erscheint auch als Druck-Ausgabe 9783540210382 Erscheint auch als Druck-Ausgabe 9783642536960 https://doi.org/10.1007/978-3-540-69494-6 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Signalling from Internalized Growth Factor Receptors Medical Microbiology Microbiology Signaltransduktion (DE-588)4318717-1 gnd Intrazellulärer Transport (DE-588)4313701-5 gnd Wachstumsfaktor (DE-588)4188802-9 gnd Rezeptor (DE-588)4049722-7 gnd Endocytose (DE-588)4152168-7 gnd |
| subject_GND | (DE-588)4318717-1 (DE-588)4313701-5 (DE-588)4188802-9 (DE-588)4049722-7 (DE-588)4152168-7 (DE-588)4143413-4 |
| title | Signalling from Internalized Growth Factor Receptors |
| title_auth | Signalling from Internalized Growth Factor Receptors |
| title_exact_search | Signalling from Internalized Growth Factor Receptors |
| title_full | Signalling from Internalized Growth Factor Receptors edited by Inger Helene Madshus |
| title_fullStr | Signalling from Internalized Growth Factor Receptors edited by Inger Helene Madshus |
| title_full_unstemmed | Signalling from Internalized Growth Factor Receptors edited by Inger Helene Madshus |
| title_short | Signalling from Internalized Growth Factor Receptors |
| title_sort | signalling from internalized growth factor receptors |
| topic | Medical Microbiology Microbiology Signaltransduktion (DE-588)4318717-1 gnd Intrazellulärer Transport (DE-588)4313701-5 gnd Wachstumsfaktor (DE-588)4188802-9 gnd Rezeptor (DE-588)4049722-7 gnd Endocytose (DE-588)4152168-7 gnd |
| topic_facet | Medical Microbiology Microbiology Signaltransduktion Intrazellulärer Transport Wachstumsfaktor Rezeptor Endocytose Aufsatzsammlung |
| url | https://doi.org/10.1007/978-3-540-69494-6 |
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