AIDS Pathogenesis:

Infection with the human immunodeficiency virus is characterized by the destruction of the host immune system as also reflected by a progressive loss of CD4-positive T-cells. This finally results in the host's incapacity to deal with opportunistic infections and the immune surveillance of tumor...

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Bibliographische Detailangaben
Weitere Verfasser: Schuitemaker, Hanneke (HerausgeberIn), Miedema, Frank 1954- (HerausgeberIn)
Format: Elektronisch E-Book
Sprache:English
Veröffentlicht: Dordrecht Springer Netherlands 2000
Schriftenreihe:Immunology and Medicine 28
Schlagworte:
Online-Zugang:UBR01
URL des Erstveröffentlichers
Zusammenfassung:Infection with the human immunodeficiency virus is characterized by the destruction of the host immune system as also reflected by a progressive loss of CD4-positive T-cells. This finally results in the host's incapacity to deal with opportunistic infections and the immune surveillance of tumors, a clinical status known as the Acquired Immunodeficiency Syndrome (AIDS). The book AIDS Pathogenesis provides the reader with a complete overview of the clinical course of HIV-1 infection. It describes the clinical aspects of primary infection, the different clinical outcomes of HIV-1 infection, and strategies for anti-viral treatment. In addition, more fundamental aspects of HIV-1 infection are reviewed. These include the biology of the virus and the novel insights in AIDS pathogenesis. Not only is the significance of an HIV-specific cellular and humoral immune response discussed, but also the possible incapacity of the adult human host to deal with T-cell destruction. Finally, the book discusses the currently used laboratory markers that allow for monitoring of the clinical course of infection
Beschreibung:1 Online-Ressource (XII, 284 p)
ISBN:9789401706858
DOI:10.1007/978-94-017-0685-8

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