Rheumatoid Arthritis: Recent Research Advances
Many advances have occurred in the last 5 years especially in understanding genetic susceptibility factors, the role of immune response in chronic arthritis and the relationship between cellular processes that underlie inflammation and tissue damage. All these are dealt with in depth in the individu...
Gespeichert in:
| Weitere Verfasser: | , , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Berlin, Heidelberg
Springer Berlin Heidelberg
1992
|
| Schlagworte: | |
| Online-Zugang: | UBR01 Volltext |
| Zusammenfassung: | Many advances have occurred in the last 5 years especially in understanding genetic susceptibility factors, the role of immune response in chronic arthritis and the relationship between cellular processes that underlie inflammation and tissue damage. All these are dealt with in depth in the individual contributions. Genetics studies included illustrate how studies of HLA genes and genes controlling the autoantibody repertoire may be involved. Environmental factors are believed to be important and studies both in humans and in experimental models on the role of viral and bacterial agents are covered. The fascinating relationship between microbes, dysregulated immune responses and oncogenes are also examined. Since autoimmunity is the key aspect of the immunological response in rheumatoid arthritis, the role of antigens is re-examined as is the part played by immune T and B cells. New areas of clinical application of basic science is well presented in this book, forexample, in examining how markers of cartilage destruction may become important in monitoring disease activity. A chapter reviewing possible future novel therapies is included |
| Beschreibung: | 1 Online-Ressource (XX, 399 p) |
| ISBN: | 9783642761898 |
| DOI: | 10.1007/978-3-642-76189-8 |
Internformat
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| 520 | |a Many advances have occurred in the last 5 years especially in understanding genetic susceptibility factors, the role of immune response in chronic arthritis and the relationship between cellular processes that underlie inflammation and tissue damage. All these are dealt with in depth in the individual contributions. Genetics studies included illustrate how studies of HLA genes and genes controlling the autoantibody repertoire may be involved. Environmental factors are believed to be important and studies both in humans and in experimental models on the role of viral and bacterial agents are covered. The fascinating relationship between microbes, dysregulated immune responses and oncogenes are also examined. Since autoimmunity is the key aspect of the immunological response in rheumatoid arthritis, the role of antigens is re-examined as is the part played by immune T and B cells. New areas of clinical application of basic science is well presented in this book, forexample, in examining how markers of cartilage destruction may become important in monitoring disease activity. A chapter reviewing possible future novel therapies is included | ||
| 650 | 4 | |a Rheumatology | |
| 650 | 4 | |a Immunology | |
| 650 | 4 | |a Orthopedics | |
| 650 | 4 | |a Rheumatology | |
| 650 | 4 | |a Immunology | |
| 650 | 4 | |a Orthopedics | |
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| dewey-ones | 616 - Diseases |
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| discipline | Medizin |
| doi_str_mv | 10.1007/978-3-642-76189-8 |
| format | Electronic eBook |
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| illustrated | Not Illustrated |
| indexdate | 2024-07-10T08:36:31Z |
| institution | BVB |
| isbn | 9783642761898 |
| language | English |
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| spelling | Rheumatoid Arthritis Recent Research Advances edited by Josef S. Smolen, Joachim R. Kalden, Ravinder N. Maini Berlin, Heidelberg Springer Berlin Heidelberg 1992 1 Online-Ressource (XX, 399 p) txt rdacontent c rdamedia cr rdacarrier Many advances have occurred in the last 5 years especially in understanding genetic susceptibility factors, the role of immune response in chronic arthritis and the relationship between cellular processes that underlie inflammation and tissue damage. All these are dealt with in depth in the individual contributions. Genetics studies included illustrate how studies of HLA genes and genes controlling the autoantibody repertoire may be involved. Environmental factors are believed to be important and studies both in humans and in experimental models on the role of viral and bacterial agents are covered. The fascinating relationship between microbes, dysregulated immune responses and oncogenes are also examined. Since autoimmunity is the key aspect of the immunological response in rheumatoid arthritis, the role of antigens is re-examined as is the part played by immune T and B cells. New areas of clinical application of basic science is well presented in this book, forexample, in examining how markers of cartilage destruction may become important in monitoring disease activity. A chapter reviewing possible future novel therapies is included Rheumatology Immunology Orthopedics Rheumatoide Arthritis (DE-588)4076708-5 gnd rswk-swf Rheumatoide Arthritis (DE-588)4076708-5 s DE-604 Smolen, Josef S. 1950- (DE-588)121027643 edt Kalden, Joachim R. 1937-2021 (DE-588)12106221X edt Maini, Ravinder N. edt Erscheint auch als Druck-Ausgabe 9783642761911 Erscheint auch als Druck-Ausgabe 9783540533153 Erscheint auch als Druck-Ausgabe 9783642761904 https://doi.org/10.1007/978-3-642-76189-8 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Rheumatoid Arthritis Recent Research Advances Rheumatology Immunology Orthopedics Rheumatoide Arthritis (DE-588)4076708-5 gnd |
| subject_GND | (DE-588)4076708-5 |
| title | Rheumatoid Arthritis Recent Research Advances |
| title_auth | Rheumatoid Arthritis Recent Research Advances |
| title_exact_search | Rheumatoid Arthritis Recent Research Advances |
| title_full | Rheumatoid Arthritis Recent Research Advances edited by Josef S. Smolen, Joachim R. Kalden, Ravinder N. Maini |
| title_fullStr | Rheumatoid Arthritis Recent Research Advances edited by Josef S. Smolen, Joachim R. Kalden, Ravinder N. Maini |
| title_full_unstemmed | Rheumatoid Arthritis Recent Research Advances edited by Josef S. Smolen, Joachim R. Kalden, Ravinder N. Maini |
| title_short | Rheumatoid Arthritis |
| title_sort | rheumatoid arthritis recent research advances |
| title_sub | Recent Research Advances |
| topic | Rheumatology Immunology Orthopedics Rheumatoide Arthritis (DE-588)4076708-5 gnd |
| topic_facet | Rheumatology Immunology Orthopedics Rheumatoide Arthritis |
| url | https://doi.org/10.1007/978-3-642-76189-8 |
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