Sex Steroids and the Cardiovascular System:
Evidence accumulated over the past decade show that gonadal steroid hormones participate in an important way in the physiological and pa thophysiological regulation of the cardiovascular system. The hor monal profile appears to put males at a disadvantage biologically in terms of cardiovascular di...
Gespeichert in:
Weitere Verfasser: | , , |
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Format: | Elektronisch E-Book |
Sprache: | English |
Veröffentlicht: |
Berlin, Heidelberg
Springer Berlin Heidelberg
1992
|
Schriftenreihe: | Ernst Schering Foundation Symposium Proceedings
5 |
Schlagworte: | |
Online-Zugang: | UBR01 Volltext |
Zusammenfassung: | Evidence accumulated over the past decade show that gonadal steroid hormones participate in an important way in the physiological and pa thophysiological regulation of the cardiovascular system. The hor monal profile appears to put males at a disadvantage biologically in terms of cardiovascular diseases. The incidence of hypertension is higher in men than in pre-monopausal women indicating an influence of gender on the hypertensive disease process. Males and females have equivalent cholesterol levels until puberty but males suffer an ex ponential increase in heart disease in their forties, while the female rise does not start until a decade later, after menopause. Animal and human studies provided ample evidence, that estrogens lower the levels of low density lipoproteins and keep high density lipoproteins elevated. These changes may be advantageous in the prevention of heart diesease. Co ronary artery atherosclerosis has been shown to be more pronounced in ovarectomized female monkeys as in intact females. Androgen, con versely, lowers the high density lipoproteins and elevates low density lipoproteins. Regarding blood pressure, it is well established that hypertension is more severe or develops more rapidly in male than fe male rats in several genetic forms of hypertension, and that gonadal steroid hormones are probably playing an important role in explaining this observation. Risk factors of human hypertension and coronary heart dies ease include menopause and ovarectomy |
Beschreibung: | 1 Online-Ressource (XII, 201 p. 26 illus) |
ISBN: | 9783662027646 |
DOI: | 10.1007/978-3-662-02764-6 |
Internformat
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245 | 1 | 0 | |a Sex Steroids and the Cardiovascular System |c edited by Peter W. Ramwell, Gabor M. Rubanyi, Ekkehard Schillinger |
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490 | 0 | |a Ernst Schering Foundation Symposium Proceedings |v 5 | |
520 | |a Evidence accumulated over the past decade show that gonadal steroid hormones participate in an important way in the physiological and pa thophysiological regulation of the cardiovascular system. The hor monal profile appears to put males at a disadvantage biologically in terms of cardiovascular diseases. The incidence of hypertension is higher in men than in pre-monopausal women indicating an influence of gender on the hypertensive disease process. Males and females have equivalent cholesterol levels until puberty but males suffer an ex ponential increase in heart disease in their forties, while the female rise does not start until a decade later, after menopause. Animal and human studies provided ample evidence, that estrogens lower the levels of low density lipoproteins and keep high density lipoproteins elevated. These changes may be advantageous in the prevention of heart diesease. Co ronary artery atherosclerosis has been shown to be more pronounced in ovarectomized female monkeys as in intact females. Androgen, con versely, lowers the high density lipoproteins and elevates low density lipoproteins. Regarding blood pressure, it is well established that hypertension is more severe or develops more rapidly in male than fe male rats in several genetic forms of hypertension, and that gonadal steroid hormones are probably playing an important role in explaining this observation. Risk factors of human hypertension and coronary heart dies ease include menopause and ovarectomy | ||
650 | 4 | |a Cardiology | |
650 | 4 | |a Endocrinology | |
650 | 4 | |a Cardiology | |
650 | 4 | |a Endocrinology | |
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Datensatz im Suchindex
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any_adam_object | |
author2 | Ramwell, Peter W. Rubanyi, Gabor M. Schillinger, Ekkehard |
author2_role | edt edt edt |
author2_variant | p w r pw pwr g m r gm gmr e s es |
author_facet | Ramwell, Peter W. Rubanyi, Gabor M. Schillinger, Ekkehard |
building | Verbundindex |
bvnumber | BV046147014 |
classification_rvk | WD 5800 |
collection | ZDB-2-SME |
ctrlnum | (ZDB-2-SME)978-3-662-02764-6 (OCoLC)1119016349 (DE-599)BVBBV046147014 |
dewey-full | 616.12 |
dewey-hundreds | 600 - Technology (Applied sciences) |
dewey-ones | 616 - Diseases |
dewey-raw | 616.12 |
dewey-search | 616.12 |
dewey-sort | 3616.12 |
dewey-tens | 610 - Medicine and health |
discipline | Biologie Medizin |
doi_str_mv | 10.1007/978-3-662-02764-6 |
format | Electronic eBook |
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genre | (DE-588)1071861417 Konferenzschrift 1992 Berlin gnd-content |
genre_facet | Konferenzschrift 1992 Berlin |
id | DE-604.BV046147014 |
illustrated | Not Illustrated |
indexdate | 2024-07-10T08:36:31Z |
institution | BVB |
isbn | 9783662027646 |
language | English |
oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-031527199 |
oclc_num | 1119016349 |
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owner_facet | DE-355 DE-BY-UBR |
physical | 1 Online-Ressource (XII, 201 p. 26 illus) |
psigel | ZDB-2-SME ZDB-2-SME_1990/2004 ZDB-2-SME ZDB-2-SME_1990/2004 |
publishDate | 1992 |
publishDateSearch | 1992 |
publishDateSort | 1992 |
publisher | Springer Berlin Heidelberg |
record_format | marc |
series2 | Ernst Schering Foundation Symposium Proceedings |
spelling | Sex Steroids and the Cardiovascular System edited by Peter W. Ramwell, Gabor M. Rubanyi, Ekkehard Schillinger Berlin, Heidelberg Springer Berlin Heidelberg 1992 1 Online-Ressource (XII, 201 p. 26 illus) txt rdacontent c rdamedia cr rdacarrier Ernst Schering Foundation Symposium Proceedings 5 Evidence accumulated over the past decade show that gonadal steroid hormones participate in an important way in the physiological and pa thophysiological regulation of the cardiovascular system. The hor monal profile appears to put males at a disadvantage biologically in terms of cardiovascular diseases. The incidence of hypertension is higher in men than in pre-monopausal women indicating an influence of gender on the hypertensive disease process. Males and females have equivalent cholesterol levels until puberty but males suffer an ex ponential increase in heart disease in their forties, while the female rise does not start until a decade later, after menopause. Animal and human studies provided ample evidence, that estrogens lower the levels of low density lipoproteins and keep high density lipoproteins elevated. These changes may be advantageous in the prevention of heart diesease. Co ronary artery atherosclerosis has been shown to be more pronounced in ovarectomized female monkeys as in intact females. Androgen, con versely, lowers the high density lipoproteins and elevates low density lipoproteins. Regarding blood pressure, it is well established that hypertension is more severe or develops more rapidly in male than fe male rats in several genetic forms of hypertension, and that gonadal steroid hormones are probably playing an important role in explaining this observation. Risk factors of human hypertension and coronary heart dies ease include menopause and ovarectomy Cardiology Endocrinology Sexualhormon (DE-588)4054683-4 gnd rswk-swf Kardiovaskuläre Krankheit (DE-588)4024666-8 gnd rswk-swf Kardiovaskuläres System (DE-588)4024665-6 gnd rswk-swf (DE-588)1071861417 Konferenzschrift 1992 Berlin gnd-content Kardiovaskuläre Krankheit (DE-588)4024666-8 s Sexualhormon (DE-588)4054683-4 s DE-604 Kardiovaskuläres System (DE-588)4024665-6 s Ramwell, Peter W. edt Rubanyi, Gabor M. edt Schillinger, Ekkehard edt Erscheint auch als Druck-Ausgabe 9783662027660 Erscheint auch als Druck-Ausgabe 9783540557289 Erscheint auch als Druck-Ausgabe 9783662027653 https://doi.org/10.1007/978-3-662-02764-6 Verlag URL des Erstveröffentlichers Volltext |
spellingShingle | Sex Steroids and the Cardiovascular System Cardiology Endocrinology Sexualhormon (DE-588)4054683-4 gnd Kardiovaskuläre Krankheit (DE-588)4024666-8 gnd Kardiovaskuläres System (DE-588)4024665-6 gnd |
subject_GND | (DE-588)4054683-4 (DE-588)4024666-8 (DE-588)4024665-6 (DE-588)1071861417 |
title | Sex Steroids and the Cardiovascular System |
title_auth | Sex Steroids and the Cardiovascular System |
title_exact_search | Sex Steroids and the Cardiovascular System |
title_full | Sex Steroids and the Cardiovascular System edited by Peter W. Ramwell, Gabor M. Rubanyi, Ekkehard Schillinger |
title_fullStr | Sex Steroids and the Cardiovascular System edited by Peter W. Ramwell, Gabor M. Rubanyi, Ekkehard Schillinger |
title_full_unstemmed | Sex Steroids and the Cardiovascular System edited by Peter W. Ramwell, Gabor M. Rubanyi, Ekkehard Schillinger |
title_short | Sex Steroids and the Cardiovascular System |
title_sort | sex steroids and the cardiovascular system |
topic | Cardiology Endocrinology Sexualhormon (DE-588)4054683-4 gnd Kardiovaskuläre Krankheit (DE-588)4024666-8 gnd Kardiovaskuläres System (DE-588)4024665-6 gnd |
topic_facet | Cardiology Endocrinology Sexualhormon Kardiovaskuläre Krankheit Kardiovaskuläres System Konferenzschrift 1992 Berlin |
url | https://doi.org/10.1007/978-3-662-02764-6 |
work_keys_str_mv | AT ramwellpeterw sexsteroidsandthecardiovascularsystem AT rubanyigaborm sexsteroidsandthecardiovascularsystem AT schillingerekkehard sexsteroidsandthecardiovascularsystem |