Innate Immunity:
Humans share a common template for innate immunity-the first-line defense that serves to limit infection immediately after exposure to microorganisms-with life forms as diverse as flowering plants and insects. In Innate Immunity, leading basic researchers explore host-pathogen interactions across an...
Gespeichert in:
Weitere Verfasser: | , |
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Format: | Elektronisch E-Book |
Sprache: | English |
Veröffentlicht: |
Totowa, NJ
Humana Press
2003
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Schriftenreihe: | Infectious Disease
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Schlagworte: | |
Online-Zugang: | UBR01 Volltext |
Zusammenfassung: | Humans share a common template for innate immunity-the first-line defense that serves to limit infection immediately after exposure to microorganisms-with life forms as diverse as flowering plants and insects. In Innate Immunity, leading basic researchers explore host-pathogen interactions across an evolutionary spectrum to elucidate the origins of the human defense system against infection. Bringing together the latest research in the field, the authors review four significant research areas: plant immunity, invertebrate host defense immunity, pattern recognition receptors in mammalian host defense, and the links between innate and adaptive immunity in mammals. They find that the similarities among insect, plant, and mammalian immunological systems shed light on the complex mechanisms involved in adaptive immunity, thereby increasing our understanding of mammalian host defense. Their description of various systems, pathways, molecules, and proteins engaged in the process of host defense suggests that innate and adaptive immunity can no longer be seen as two different systems, but rather as working in tandem to surround and destroy foreign agents that enter the body. The authors also discuss those templates of innate immunity found in primitive systems that are now driving most novel research on human innate immunity. Innovative and cutting-edge, Innate Immunity demonstrates new ways to explore this system in plants, invertebrates, and mammals, and, by illuminating the dynamic interplay between infectious agents and host defense, clearly reveals the potential for improved therapies to treat infectious diseases |
Beschreibung: | 1 Online-Ressource (XI, 410 p. 60 illus) |
ISBN: | 9781592593200 |
DOI: | 10.1007/978-1-59259-320-0 |
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520 | |a Humans share a common template for innate immunity-the first-line defense that serves to limit infection immediately after exposure to microorganisms-with life forms as diverse as flowering plants and insects. In Innate Immunity, leading basic researchers explore host-pathogen interactions across an evolutionary spectrum to elucidate the origins of the human defense system against infection. Bringing together the latest research in the field, the authors review four significant research areas: plant immunity, invertebrate host defense immunity, pattern recognition receptors in mammalian host defense, and the links between innate and adaptive immunity in mammals. They find that the similarities among insect, plant, and mammalian immunological systems shed light on the complex mechanisms involved in adaptive immunity, thereby increasing our understanding of mammalian host defense. Their description of various systems, pathways, molecules, and proteins engaged in the process of host defense suggests that innate and adaptive immunity can no longer be seen as two different systems, but rather as working in tandem to surround and destroy foreign agents that enter the body. The authors also discuss those templates of innate immunity found in primitive systems that are now driving most novel research on human innate immunity. Innovative and cutting-edge, Innate Immunity demonstrates new ways to explore this system in plants, invertebrates, and mammals, and, by illuminating the dynamic interplay between infectious agents and host defense, clearly reveals the potential for improved therapies to treat infectious diseases | ||
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author2 | Ezekowitz, R. Alan B. Hoffmann, Jules A. |
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author_facet | Ezekowitz, R. Alan B. Hoffmann, Jules A. |
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dewey-ones | 616 - Diseases |
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dewey-tens | 610 - Medicine and health |
discipline | Medizin |
doi_str_mv | 10.1007/978-1-59259-320-0 |
format | Electronic eBook |
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id | DE-604.BV046146990 |
illustrated | Not Illustrated |
indexdate | 2024-07-10T08:36:31Z |
institution | BVB |
isbn | 9781592593200 |
language | English |
oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-031527175 |
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physical | 1 Online-Ressource (XI, 410 p. 60 illus) |
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publishDate | 2003 |
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publisher | Humana Press |
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series2 | Infectious Disease |
spelling | Innate Immunity edited by R. Alan B. Ezekowitz, Jules A. Hoffmann Totowa, NJ Humana Press 2003 1 Online-Ressource (XI, 410 p. 60 illus) txt rdacontent c rdamedia cr rdacarrier Infectious Disease Humans share a common template for innate immunity-the first-line defense that serves to limit infection immediately after exposure to microorganisms-with life forms as diverse as flowering plants and insects. In Innate Immunity, leading basic researchers explore host-pathogen interactions across an evolutionary spectrum to elucidate the origins of the human defense system against infection. Bringing together the latest research in the field, the authors review four significant research areas: plant immunity, invertebrate host defense immunity, pattern recognition receptors in mammalian host defense, and the links between innate and adaptive immunity in mammals. They find that the similarities among insect, plant, and mammalian immunological systems shed light on the complex mechanisms involved in adaptive immunity, thereby increasing our understanding of mammalian host defense. Their description of various systems, pathways, molecules, and proteins engaged in the process of host defense suggests that innate and adaptive immunity can no longer be seen as two different systems, but rather as working in tandem to surround and destroy foreign agents that enter the body. The authors also discuss those templates of innate immunity found in primitive systems that are now driving most novel research on human innate immunity. Innovative and cutting-edge, Innate Immunity demonstrates new ways to explore this system in plants, invertebrates, and mammals, and, by illuminating the dynamic interplay between infectious agents and host defense, clearly reveals the potential for improved therapies to treat infectious diseases Immunology Ezekowitz, R. Alan B. edt Hoffmann, Jules A. edt Erscheint auch als Druck-Ausgabe 9781468497465 Erscheint auch als Druck-Ausgabe 9781588290465 Erscheint auch als Druck-Ausgabe 9781468497458 https://doi.org/10.1007/978-1-59259-320-0 Verlag URL des Erstveröffentlichers Volltext |
spellingShingle | Innate Immunity Immunology |
title | Innate Immunity |
title_auth | Innate Immunity |
title_exact_search | Innate Immunity |
title_full | Innate Immunity edited by R. Alan B. Ezekowitz, Jules A. Hoffmann |
title_fullStr | Innate Immunity edited by R. Alan B. Ezekowitz, Jules A. Hoffmann |
title_full_unstemmed | Innate Immunity edited by R. Alan B. Ezekowitz, Jules A. Hoffmann |
title_short | Innate Immunity |
title_sort | innate immunity |
topic | Immunology |
topic_facet | Immunology |
url | https://doi.org/10.1007/978-1-59259-320-0 |
work_keys_str_mv | AT ezekowitzralanb innateimmunity AT hoffmannjulesa innateimmunity |