It has been recognized for almost 200 years that certain families seem to inherit cancer. It is only in the past decade, however, that molecular genetics and epidemiology have combined to define the role of inheritance in cancer more clearly, and to identify some of the genes involved. The causative...

Ausführliche Beschreibung

Bibliographische Detailangaben

Weitere Verfasser:	Ponder, B. A. J. (HerausgeberIn), Waring, M. J. (HerausgeberIn)
Format:	Elektronisch E-Book
Sprache:	English
Veröffentlicht:	Dordrecht Springer Netherlands 1995
Schriftenreihe:	Cancer Biology and Medicine 4
Schlagworte:	Oncology Human Genetics Oncology   Human genetics Krebs > Medizin Molekulargenetik Aufsatzsammlung
Online-Zugang:	UBR01 URL des Erstveröffentlichers
Zusammenfassung:	It has been recognized for almost 200 years that certain families seem to inherit cancer. It is only in the past decade, however, that molecular genetics and epidemiology have combined to define the role of inheritance in cancer more clearly, and to identify some of the genes involved. The causative genes can be tracked through cancer-prone families via genetic linkage and positional cloning. Several of the genes discovered have subsequently been proved to play critical roles in normal growth and development. There are also implications for the families themselves in terms of genetic testing with its attendant dilemmas, if it is not clear that useful action will result. The chapters in The Genetics of Cancer illustrate what has already been achieved and take a critical look at the future directions of this research and its potential clinical applications
Beschreibung:	1 Online-Ressource (IX, 221 p)
ISBN:	9789401106771
DOI:	10.1007/978-94-011-0677-1