Hormonal Carcinogenesis III: Proceedings of the Third International Symposium
Since our previous symposium in 1995, the pace of research in hormones and cancer has accelerated. Progress in our understanding of hormonal carcinogenic processes has been a direct result of the advances made in cell biology, endocrinology, and carcinogenesis at the molecular level. The newer field...
Gespeichert in:
| Weitere Verfasser: | , , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
New York, NY
Springer New York
2001
|
| Schlagworte: | |
| Online-Zugang: | UBR01 URL des Erstveröffentlichers |
| Zusammenfassung: | Since our previous symposium in 1995, the pace of research in hormones and cancer has accelerated. Progress in our understanding of hormonal carcinogenic processes has been a direct result of the advances made in cell biology, endocrinology, and carcinogenesis at the molecular level. The newer fields of molecular genetics and cytogenetics already have and are expected to continue to playa major role in furthering our understanding of the cellular and molecular events in hormonal carcinogenesis. It has become increasingly clear that the risk of naturally occurring sex hormones in carcinogenic processes, both in human and in animal models, requires only minute quantities of hormones, at both the serum and tissue levels. Moreover, hormone target tissues for neoplastic transformation, perhaps with the exception of the liver, generally have relatively modest ability to metabolize sex hormones, such as the breast and prostate. Table 1 summarizes the serum, and in most cases, the tissue levels of sex hormones, both endogenously and exogenously ingested, which are associated with increased risk for endocrine-associated cancers such as breast, endometrium, and prostate, as well as the hormone levels of four experimental models that have been shown to elicit high tumor incidences. In contrast to the human, in which the hormone levels are cyclic, however, the latter require continuous hormone exposure at these relatively low levels |
| Beschreibung: | 1 Online-Ressource (XLIII, 555 p) |
| ISBN: | 9781461220923 |
| DOI: | 10.1007/978-1-4612-2092-3 |
Internformat
MARC
| LEADER | 00000nmm a2200000zc 4500 | ||
|---|---|---|---|
| 001 | BV046145478 | ||
| 003 | DE-604 | ||
| 005 | 00000000000000.0 | ||
| 007 | cr|uuu---uuuuu | ||
| 008 | 190905s2001 |||| o||u| ||||||eng d | ||
| 020 | |a 9781461220923 |9 978-1-4612-2092-3 | ||
| 024 | 7 | |a 10.1007/978-1-4612-2092-3 |2 doi | |
| 035 | |a (ZDB-2-SME)978-1-4612-2092-3 | ||
| 035 | |a (OCoLC)1119009227 | ||
| 035 | |a (DE-599)BVBBV046145478 | ||
| 040 | |a DE-604 |b ger |e aacr | ||
| 041 | 0 | |a eng | |
| 049 | |a DE-355 | ||
| 082 | 0 | |a 616.994 |2 23 | |
| 084 | |a XH 5305 |0 (DE-625)152911:12911 |2 rvk | ||
| 245 | 1 | 0 | |a Hormonal Carcinogenesis III |b Proceedings of the Third International Symposium |c edited by Jonathan J. Li, Sara Antonia Li, Janet R. Daling |
| 264 | 1 | |a New York, NY |b Springer New York |c 2001 | |
| 300 | |a 1 Online-Ressource (XLIII, 555 p) | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b c |2 rdamedia | ||
| 338 | |b cr |2 rdacarrier | ||
| 520 | |a Since our previous symposium in 1995, the pace of research in hormones and cancer has accelerated. Progress in our understanding of hormonal carcinogenic processes has been a direct result of the advances made in cell biology, endocrinology, and carcinogenesis at the molecular level. The newer fields of molecular genetics and cytogenetics already have and are expected to continue to playa major role in furthering our understanding of the cellular and molecular events in hormonal carcinogenesis. It has become increasingly clear that the risk of naturally occurring sex hormones in carcinogenic processes, both in human and in animal models, requires only minute quantities of hormones, at both the serum and tissue levels. Moreover, hormone target tissues for neoplastic transformation, perhaps with the exception of the liver, generally have relatively modest ability to metabolize sex hormones, such as the breast and prostate. Table 1 summarizes the serum, and in most cases, the tissue levels of sex hormones, both endogenously and exogenously ingested, which are associated with increased risk for endocrine-associated cancers such as breast, endometrium, and prostate, as well as the hormone levels of four experimental models that have been shown to elicit high tumor incidences. In contrast to the human, in which the hormone levels are cyclic, however, the latter require continuous hormone exposure at these relatively low levels | ||
| 650 | 4 | |a Oncology | |
| 650 | 4 | |a Oncology | |
| 650 | 0 | 7 | |a Hormon |0 (DE-588)4025864-6 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Carcinogenese |0 (DE-588)4069853-1 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Carcinogenität |0 (DE-588)4206051-5 |2 gnd |9 rswk-swf |
| 655 | 7 | |8 1\p |0 (DE-588)1071861417 |a Konferenzschrift |y 1998 |z Seattle Wash. |2 gnd-content | |
| 689 | 0 | 0 | |a Hormon |0 (DE-588)4025864-6 |D s |
| 689 | 0 | 1 | |a Carcinogenität |0 (DE-588)4206051-5 |D s |
| 689 | 0 | |8 2\p |5 DE-604 | |
| 689 | 1 | 0 | |a Hormon |0 (DE-588)4025864-6 |D s |
| 689 | 1 | 1 | |a Carcinogenese |0 (DE-588)4069853-1 |D s |
| 689 | 1 | |8 3\p |5 DE-604 | |
| 700 | 1 | |a Li, Jonathan J. |4 edt | |
| 700 | 1 | |a Li, Sara Antonia |4 edt | |
| 700 | 1 | |a Daling, Janet R. |4 edt | |
| 776 | 0 | 8 | |i Erscheint auch als |n Druck-Ausgabe |z 9781461274117 |
| 776 | 0 | 8 | |i Erscheint auch als |n Druck-Ausgabe |z 9780387951270 |
| 776 | 0 | 8 | |i Erscheint auch als |n Druck-Ausgabe |z 9781461220930 |
| 856 | 4 | 0 | |u https://doi.org/10.1007/978-1-4612-2092-3 |x Verlag |z URL des Erstveröffentlichers |3 Volltext |
| 912 | |a ZDB-2-SME | ||
| 940 | 1 | |q ZDB-2-SME_1990/2004 | |
| 999 | |a oai:aleph.bib-bvb.de:BVB01-031525663 | ||
| 883 | 1 | |8 1\p |a cgwrk |d 20201028 |q DE-101 |u https://d-nb.info/provenance/plan#cgwrk | |
| 883 | 1 | |8 2\p |a cgwrk |d 20201028 |q DE-101 |u https://d-nb.info/provenance/plan#cgwrk | |
| 883 | 1 | |8 3\p |a cgwrk |d 20201028 |q DE-101 |u https://d-nb.info/provenance/plan#cgwrk | |
| 966 | e | |u https://doi.org/10.1007/978-1-4612-2092-3 |l UBR01 |p ZDB-2-SME |q ZDB-2-SME_1990/2004 |x Verlag |3 Volltext | |
Datensatz im Suchindex
| _version_ | 1804180482189950976 |
|---|---|
| any_adam_object | |
| author2 | Li, Jonathan J. Li, Sara Antonia Daling, Janet R. |
| author2_role | edt edt edt |
| author2_variant | j j l jj jjl s a l sa sal j r d jr jrd |
| author_facet | Li, Jonathan J. Li, Sara Antonia Daling, Janet R. |
| building | Verbundindex |
| bvnumber | BV046145478 |
| classification_rvk | XH 5305 |
| collection | ZDB-2-SME |
| ctrlnum | (ZDB-2-SME)978-1-4612-2092-3 (OCoLC)1119009227 (DE-599)BVBBV046145478 |
| dewey-full | 616.994 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 616 - Diseases |
| dewey-raw | 616.994 |
| dewey-search | 616.994 |
| dewey-sort | 3616.994 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| doi_str_mv | 10.1007/978-1-4612-2092-3 |
| format | Electronic eBook |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>03846nmm a2200601zc 4500</leader><controlfield tag="001">BV046145478</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">00000000000000.0</controlfield><controlfield tag="007">cr|uuu---uuuuu</controlfield><controlfield tag="008">190905s2001 |||| o||u| ||||||eng d</controlfield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9781461220923</subfield><subfield code="9">978-1-4612-2092-3</subfield></datafield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1007/978-1-4612-2092-3</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ZDB-2-SME)978-1-4612-2092-3</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)1119009227</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV046145478</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">aacr</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-355</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">616.994</subfield><subfield code="2">23</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">XH 5305</subfield><subfield code="0">(DE-625)152911:12911</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Hormonal Carcinogenesis III</subfield><subfield code="b">Proceedings of the Third International Symposium</subfield><subfield code="c">edited by Jonathan J. Li, Sara Antonia Li, Janet R. Daling</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">New York, NY</subfield><subfield code="b">Springer New York</subfield><subfield code="c">2001</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 Online-Ressource (XLIII, 555 p)</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Since our previous symposium in 1995, the pace of research in hormones and cancer has accelerated. Progress in our understanding of hormonal carcinogenic processes has been a direct result of the advances made in cell biology, endocrinology, and carcinogenesis at the molecular level. The newer fields of molecular genetics and cytogenetics already have and are expected to continue to playa major role in furthering our understanding of the cellular and molecular events in hormonal carcinogenesis. It has become increasingly clear that the risk of naturally occurring sex hormones in carcinogenic processes, both in human and in animal models, requires only minute quantities of hormones, at both the serum and tissue levels. Moreover, hormone target tissues for neoplastic transformation, perhaps with the exception of the liver, generally have relatively modest ability to metabolize sex hormones, such as the breast and prostate. Table 1 summarizes the serum, and in most cases, the tissue levels of sex hormones, both endogenously and exogenously ingested, which are associated with increased risk for endocrine-associated cancers such as breast, endometrium, and prostate, as well as the hormone levels of four experimental models that have been shown to elicit high tumor incidences. In contrast to the human, in which the hormone levels are cyclic, however, the latter require continuous hormone exposure at these relatively low levels</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Oncology</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Oncology </subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Hormon</subfield><subfield code="0">(DE-588)4025864-6</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Carcinogenese</subfield><subfield code="0">(DE-588)4069853-1</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Carcinogenität</subfield><subfield code="0">(DE-588)4206051-5</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="655" ind1=" " ind2="7"><subfield code="8">1\p</subfield><subfield code="0">(DE-588)1071861417</subfield><subfield code="a">Konferenzschrift</subfield><subfield code="y">1998</subfield><subfield code="z">Seattle Wash.</subfield><subfield code="2">gnd-content</subfield></datafield><datafield tag="689" ind1="0" ind2="0"><subfield code="a">Hormon</subfield><subfield code="0">(DE-588)4025864-6</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="1"><subfield code="a">Carcinogenität</subfield><subfield code="0">(DE-588)4206051-5</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2=" "><subfield code="8">2\p</subfield><subfield code="5">DE-604</subfield></datafield><datafield tag="689" ind1="1" ind2="0"><subfield code="a">Hormon</subfield><subfield code="0">(DE-588)4025864-6</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="1" ind2="1"><subfield code="a">Carcinogenese</subfield><subfield code="0">(DE-588)4069853-1</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="1" ind2=" "><subfield code="8">3\p</subfield><subfield code="5">DE-604</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Li, Jonathan J.</subfield><subfield code="4">edt</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Li, Sara Antonia</subfield><subfield code="4">edt</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Daling, Janet R.</subfield><subfield code="4">edt</subfield></datafield><datafield tag="776" ind1="0" ind2="8"><subfield code="i">Erscheint auch als</subfield><subfield code="n">Druck-Ausgabe</subfield><subfield code="z">9781461274117</subfield></datafield><datafield tag="776" ind1="0" ind2="8"><subfield code="i">Erscheint auch als</subfield><subfield code="n">Druck-Ausgabe</subfield><subfield code="z">9780387951270</subfield></datafield><datafield tag="776" ind1="0" ind2="8"><subfield code="i">Erscheint auch als</subfield><subfield code="n">Druck-Ausgabe</subfield><subfield code="z">9781461220930</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.1007/978-1-4612-2092-3</subfield><subfield code="x">Verlag</subfield><subfield code="z">URL des Erstveröffentlichers</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-2-SME</subfield></datafield><datafield tag="940" ind1="1" ind2=" "><subfield code="q">ZDB-2-SME_1990/2004</subfield></datafield><datafield tag="999" ind1=" " ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-031525663</subfield></datafield><datafield tag="883" ind1="1" ind2=" "><subfield code="8">1\p</subfield><subfield code="a">cgwrk</subfield><subfield code="d">20201028</subfield><subfield code="q">DE-101</subfield><subfield code="u">https://d-nb.info/provenance/plan#cgwrk</subfield></datafield><datafield tag="883" ind1="1" ind2=" "><subfield code="8">2\p</subfield><subfield code="a">cgwrk</subfield><subfield code="d">20201028</subfield><subfield code="q">DE-101</subfield><subfield code="u">https://d-nb.info/provenance/plan#cgwrk</subfield></datafield><datafield tag="883" ind1="1" ind2=" "><subfield code="8">3\p</subfield><subfield code="a">cgwrk</subfield><subfield code="d">20201028</subfield><subfield code="q">DE-101</subfield><subfield code="u">https://d-nb.info/provenance/plan#cgwrk</subfield></datafield><datafield tag="966" ind1="e" ind2=" "><subfield code="u">https://doi.org/10.1007/978-1-4612-2092-3</subfield><subfield code="l">UBR01</subfield><subfield code="p">ZDB-2-SME</subfield><subfield code="q">ZDB-2-SME_1990/2004</subfield><subfield code="x">Verlag</subfield><subfield code="3">Volltext</subfield></datafield></record></collection> |
| genre | 1\p (DE-588)1071861417 Konferenzschrift 1998 Seattle Wash. gnd-content |
| genre_facet | Konferenzschrift 1998 Seattle Wash. |
| id | DE-604.BV046145478 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T08:36:27Z |
| institution | BVB |
| isbn | 9781461220923 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-031525663 |
| oclc_num | 1119009227 |
| open_access_boolean | |
| owner | DE-355 DE-BY-UBR |
| owner_facet | DE-355 DE-BY-UBR |
| physical | 1 Online-Ressource (XLIII, 555 p) |
| psigel | ZDB-2-SME ZDB-2-SME_1990/2004 ZDB-2-SME ZDB-2-SME_1990/2004 |
| publishDate | 2001 |
| publishDateSearch | 2001 |
| publishDateSort | 2001 |
| publisher | Springer New York |
| record_format | marc |
| spelling | Hormonal Carcinogenesis III Proceedings of the Third International Symposium edited by Jonathan J. Li, Sara Antonia Li, Janet R. Daling New York, NY Springer New York 2001 1 Online-Ressource (XLIII, 555 p) txt rdacontent c rdamedia cr rdacarrier Since our previous symposium in 1995, the pace of research in hormones and cancer has accelerated. Progress in our understanding of hormonal carcinogenic processes has been a direct result of the advances made in cell biology, endocrinology, and carcinogenesis at the molecular level. The newer fields of molecular genetics and cytogenetics already have and are expected to continue to playa major role in furthering our understanding of the cellular and molecular events in hormonal carcinogenesis. It has become increasingly clear that the risk of naturally occurring sex hormones in carcinogenic processes, both in human and in animal models, requires only minute quantities of hormones, at both the serum and tissue levels. Moreover, hormone target tissues for neoplastic transformation, perhaps with the exception of the liver, generally have relatively modest ability to metabolize sex hormones, such as the breast and prostate. Table 1 summarizes the serum, and in most cases, the tissue levels of sex hormones, both endogenously and exogenously ingested, which are associated with increased risk for endocrine-associated cancers such as breast, endometrium, and prostate, as well as the hormone levels of four experimental models that have been shown to elicit high tumor incidences. In contrast to the human, in which the hormone levels are cyclic, however, the latter require continuous hormone exposure at these relatively low levels Oncology Oncology Hormon (DE-588)4025864-6 gnd rswk-swf Carcinogenese (DE-588)4069853-1 gnd rswk-swf Carcinogenität (DE-588)4206051-5 gnd rswk-swf 1\p (DE-588)1071861417 Konferenzschrift 1998 Seattle Wash. gnd-content Hormon (DE-588)4025864-6 s Carcinogenität (DE-588)4206051-5 s 2\p DE-604 Carcinogenese (DE-588)4069853-1 s 3\p DE-604 Li, Jonathan J. edt Li, Sara Antonia edt Daling, Janet R. edt Erscheint auch als Druck-Ausgabe 9781461274117 Erscheint auch als Druck-Ausgabe 9780387951270 Erscheint auch als Druck-Ausgabe 9781461220930 https://doi.org/10.1007/978-1-4612-2092-3 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 2\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 3\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Hormonal Carcinogenesis III Proceedings of the Third International Symposium Oncology Oncology Hormon (DE-588)4025864-6 gnd Carcinogenese (DE-588)4069853-1 gnd Carcinogenität (DE-588)4206051-5 gnd |
| subject_GND | (DE-588)4025864-6 (DE-588)4069853-1 (DE-588)4206051-5 (DE-588)1071861417 |
| title | Hormonal Carcinogenesis III Proceedings of the Third International Symposium |
| title_auth | Hormonal Carcinogenesis III Proceedings of the Third International Symposium |
| title_exact_search | Hormonal Carcinogenesis III Proceedings of the Third International Symposium |
| title_full | Hormonal Carcinogenesis III Proceedings of the Third International Symposium edited by Jonathan J. Li, Sara Antonia Li, Janet R. Daling |
| title_fullStr | Hormonal Carcinogenesis III Proceedings of the Third International Symposium edited by Jonathan J. Li, Sara Antonia Li, Janet R. Daling |
| title_full_unstemmed | Hormonal Carcinogenesis III Proceedings of the Third International Symposium edited by Jonathan J. Li, Sara Antonia Li, Janet R. Daling |
| title_short | Hormonal Carcinogenesis III |
| title_sort | hormonal carcinogenesis iii proceedings of the third international symposium |
| title_sub | Proceedings of the Third International Symposium |
| topic | Oncology Oncology Hormon (DE-588)4025864-6 gnd Carcinogenese (DE-588)4069853-1 gnd Carcinogenität (DE-588)4206051-5 gnd |
| topic_facet | Oncology Oncology Hormon Carcinogenese Carcinogenität Konferenzschrift 1998 Seattle Wash. |
| url | https://doi.org/10.1007/978-1-4612-2092-3 |
| work_keys_str_mv | AT lijonathanj hormonalcarcinogenesisiiiproceedingsofthethirdinternationalsymposium AT lisaraantonia hormonalcarcinogenesisiiiproceedingsofthethirdinternationalsymposium AT dalingjanetr hormonalcarcinogenesisiiiproceedingsofthethirdinternationalsymposium |