Port-Site and Wound Recurrences in Cancer Surgery: Incidence - Pathogenesis - Prevention
During the past 9 years, reports of 'port-site' deposits following laparoscopic surgery for malignancy, especially laparoscopic resection of colonic cancer, have cast a shadow on the wisdom of the laparoscopic approach in the surgical man agement in patients with cancer. Those reports of...
Gespeichert in:
| Weitere Verfasser: | , , |
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| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Berlin, Heidelberg
Springer Berlin Heidelberg
2000
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| Schlagworte: | |
| Online-Zugang: | UBR01 Volltext |
| Zusammenfassung: | During the past 9 years, reports of 'port-site' deposits following laparoscopic surgery for malignancy, especially laparoscopic resection of colonic cancer, have cast a shadow on the wisdom of the laparoscopic approach in the surgical man agement in patients with cancer. Those reports of port-site deposits, some 90 cases reported in the literature up to 1999, have opened a 'can of worms' and highlighted the scarcity of our knowledge on cancer cell migration from solid tu mors and the factors that underlie their successful implantation in surgical wounds both in the presence and absence of a positive pressure pneumoperito neum. The jury is out even in relation to the effect of the healing surgical access wound - do the biochemical and cellular repair processes and the associated growth factors enhance or prevent implantation of exfoliated viable tumor cells? Whatever the answer to this question, it is clear that tumor cells do implant in healing surgical wounds and the key question is whether this is facilitated by lap aroscopic surgery with CO pneumoperitoneum compared to the traditional 2 surgical exposure. It is known that tumors shed malignant cells into the blood stream, the peritoneal cavity and in the case of hollow organs, intraluminally. Equally there is good evidence that surgical and instrumental manipulation of tumors induce exfoliation of viable tumor cells |
| Beschreibung: | 1 Online-Ressource (XV, 136 p. 14 illus) |
| ISBN: | 9783642570285 |
| DOI: | 10.1007/978-3-642-57028-5 |
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| 520 | |a During the past 9 years, reports of 'port-site' deposits following laparoscopic surgery for malignancy, especially laparoscopic resection of colonic cancer, have cast a shadow on the wisdom of the laparoscopic approach in the surgical man agement in patients with cancer. Those reports of port-site deposits, some 90 cases reported in the literature up to 1999, have opened a 'can of worms' and highlighted the scarcity of our knowledge on cancer cell migration from solid tu mors and the factors that underlie their successful implantation in surgical wounds both in the presence and absence of a positive pressure pneumoperito neum. The jury is out even in relation to the effect of the healing surgical access wound - do the biochemical and cellular repair processes and the associated growth factors enhance or prevent implantation of exfoliated viable tumor cells? Whatever the answer to this question, it is clear that tumor cells do implant in healing surgical wounds and the key question is whether this is facilitated by lap aroscopic surgery with CO pneumoperitoneum compared to the traditional 2 surgical exposure. It is known that tumors shed malignant cells into the blood stream, the peritoneal cavity and in the case of hollow organs, intraluminally. Equally there is good evidence that surgical and instrumental manipulation of tumors induce exfoliation of viable tumor cells | ||
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Datensatz im Suchindex
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| discipline | Medizin |
| doi_str_mv | 10.1007/978-3-642-57028-5 |
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| illustrated | Not Illustrated |
| indexdate | 2024-07-10T08:36:26Z |
| institution | BVB |
| isbn | 9783642570285 |
| language | English |
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| spelling | Port-Site and Wound Recurrences in Cancer Surgery Incidence - Pathogenesis - Prevention edited by Marc A. Reymond, H. Jaap Bonjer, Ferdinand Köckerling Berlin, Heidelberg Springer Berlin Heidelberg 2000 1 Online-Ressource (XV, 136 p. 14 illus) txt rdacontent c rdamedia cr rdacarrier During the past 9 years, reports of 'port-site' deposits following laparoscopic surgery for malignancy, especially laparoscopic resection of colonic cancer, have cast a shadow on the wisdom of the laparoscopic approach in the surgical man agement in patients with cancer. Those reports of port-site deposits, some 90 cases reported in the literature up to 1999, have opened a 'can of worms' and highlighted the scarcity of our knowledge on cancer cell migration from solid tu mors and the factors that underlie their successful implantation in surgical wounds both in the presence and absence of a positive pressure pneumoperito neum. The jury is out even in relation to the effect of the healing surgical access wound - do the biochemical and cellular repair processes and the associated growth factors enhance or prevent implantation of exfoliated viable tumor cells? Whatever the answer to this question, it is clear that tumor cells do implant in healing surgical wounds and the key question is whether this is facilitated by lap aroscopic surgery with CO pneumoperitoneum compared to the traditional 2 surgical exposure. It is known that tumors shed malignant cells into the blood stream, the peritoneal cavity and in the case of hollow organs, intraluminally. Equally there is good evidence that surgical and instrumental manipulation of tumors induce exfoliation of viable tumor cells Surgery Gastroenterology Oncology Oncology Minimal-invasive Chirurgie (DE-588)4327907-7 gnd rswk-swf Transplantationstumor (DE-588)4503758-9 gnd rswk-swf Krebs Medizin (DE-588)4073781-0 gnd rswk-swf Krebs Medizin (DE-588)4073781-0 s Minimal-invasive Chirurgie (DE-588)4327907-7 s Transplantationstumor (DE-588)4503758-9 s DE-604 Reymond, Marc A. edt Bonjer, H. Jaap edt Köckerling, Ferdinand edt Erscheint auch als Druck-Ausgabe 9783540669296 Erscheint auch als Druck-Ausgabe 9783642631177 Erscheint auch als Druck-Ausgabe 9783642570292 https://doi.org/10.1007/978-3-642-57028-5 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Port-Site and Wound Recurrences in Cancer Surgery Incidence - Pathogenesis - Prevention Surgery Gastroenterology Oncology Oncology Minimal-invasive Chirurgie (DE-588)4327907-7 gnd Transplantationstumor (DE-588)4503758-9 gnd Krebs Medizin (DE-588)4073781-0 gnd |
| subject_GND | (DE-588)4327907-7 (DE-588)4503758-9 (DE-588)4073781-0 |
| title | Port-Site and Wound Recurrences in Cancer Surgery Incidence - Pathogenesis - Prevention |
| title_auth | Port-Site and Wound Recurrences in Cancer Surgery Incidence - Pathogenesis - Prevention |
| title_exact_search | Port-Site and Wound Recurrences in Cancer Surgery Incidence - Pathogenesis - Prevention |
| title_full | Port-Site and Wound Recurrences in Cancer Surgery Incidence - Pathogenesis - Prevention edited by Marc A. Reymond, H. Jaap Bonjer, Ferdinand Köckerling |
| title_fullStr | Port-Site and Wound Recurrences in Cancer Surgery Incidence - Pathogenesis - Prevention edited by Marc A. Reymond, H. Jaap Bonjer, Ferdinand Köckerling |
| title_full_unstemmed | Port-Site and Wound Recurrences in Cancer Surgery Incidence - Pathogenesis - Prevention edited by Marc A. Reymond, H. Jaap Bonjer, Ferdinand Köckerling |
| title_short | Port-Site and Wound Recurrences in Cancer Surgery |
| title_sort | port site and wound recurrences in cancer surgery incidence pathogenesis prevention |
| title_sub | Incidence - Pathogenesis - Prevention |
| topic | Surgery Gastroenterology Oncology Oncology Minimal-invasive Chirurgie (DE-588)4327907-7 gnd Transplantationstumor (DE-588)4503758-9 gnd Krebs Medizin (DE-588)4073781-0 gnd |
| topic_facet | Surgery Gastroenterology Oncology Oncology Minimal-invasive Chirurgie Transplantationstumor Krebs Medizin |
| url | https://doi.org/10.1007/978-3-642-57028-5 |
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