The Endothelium in Cardiovascular Disease: Pathophysiology, Clinical Presentation and Pharmacotherapy
The endothelium is an important regulator of the cardiovascular system by releasing nitric oxide, prostacyclin, endothelin-1, and other endothelium-derived constricting factors which are able to profoundly affect vascular tone and the function of circulating blood cells such as platelets and monocyt...
Saved in:
| Other Authors: | |
|---|---|
| Format: | Electronic eBook |
| Language: | English |
| Published: |
Berlin, Heidelberg
Springer Berlin Heidelberg
1995
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| Subjects: | |
| Online Access: | UBR01 Volltext |
| Summary: | The endothelium is an important regulator of the cardiovascular system by releasing nitric oxide, prostacyclin, endothelin-1, and other endothelium-derived constricting factors which are able to profoundly affect vascular tone and the function of circulating blood cells such as platelets and monocytes. In addition, the endothelium is a source of factors which can activate or inhibit vascular smooth muscle cell migration and proliferation. Endothelial dysfunction, with an imbalanced production of these factors, therefore, can profoundly affect vascular tone and structure as well as the function of circulating blood cells. Endothelial dysfunction has been demonstrated in various forms of cardiovascular diseasae. Cardiovascular drugs already in clinical use or in development are able to interfere with certain aspects of endothelial function and may be useful in protecting the vessels and, hence, in preventing the development of cardiovascular disease |
| Physical Description: | 1 Online-Ressource (XI, 197 p. 26 illus) |
| ISBN: | 9783642798030 |
| DOI: | 10.1007/978-3-642-79803-0 |
Staff View
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| 520 | |a The endothelium is an important regulator of the cardiovascular system by releasing nitric oxide, prostacyclin, endothelin-1, and other endothelium-derived constricting factors which are able to profoundly affect vascular tone and the function of circulating blood cells such as platelets and monocytes. In addition, the endothelium is a source of factors which can activate or inhibit vascular smooth muscle cell migration and proliferation. Endothelial dysfunction, with an imbalanced production of these factors, therefore, can profoundly affect vascular tone and structure as well as the function of circulating blood cells. Endothelial dysfunction has been demonstrated in various forms of cardiovascular diseasae. Cardiovascular drugs already in clinical use or in development are able to interfere with certain aspects of endothelial function and may be useful in protecting the vessels and, hence, in preventing the development of cardiovascular disease | ||
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| indexdate | 2024-07-10T08:36:25Z |
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| isbn | 9783642798030 |
| language | English |
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| spelling | The Endothelium in Cardiovascular Disease Pathophysiology, Clinical Presentation and Pharmacotherapy edited by Thomas F. Lüscher Berlin, Heidelberg Springer Berlin Heidelberg 1995 1 Online-Ressource (XI, 197 p. 26 illus) txt rdacontent c rdamedia cr rdacarrier The endothelium is an important regulator of the cardiovascular system by releasing nitric oxide, prostacyclin, endothelin-1, and other endothelium-derived constricting factors which are able to profoundly affect vascular tone and the function of circulating blood cells such as platelets and monocytes. In addition, the endothelium is a source of factors which can activate or inhibit vascular smooth muscle cell migration and proliferation. Endothelial dysfunction, with an imbalanced production of these factors, therefore, can profoundly affect vascular tone and structure as well as the function of circulating blood cells. Endothelial dysfunction has been demonstrated in various forms of cardiovascular diseasae. Cardiovascular drugs already in clinical use or in development are able to interfere with certain aspects of endothelial function and may be useful in protecting the vessels and, hence, in preventing the development of cardiovascular disease Cardiology Human Physiology Pharmacology/Toxicology Human physiology Toxicology Endothelium-derived relaxing factor (DE-588)4236888-1 gnd rswk-swf Kardiovaskuläre Krankheit (DE-588)4024666-8 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Kardiovaskuläre Krankheit (DE-588)4024666-8 s Endothelium-derived relaxing factor (DE-588)4236888-1 s DE-604 Lüscher, Thomas F. edt Erscheint auch als Druck-Ausgabe 9783642798054 Erscheint auch als Druck-Ausgabe 9783540593522 Erscheint auch als Druck-Ausgabe 9783642798047 https://doi.org/10.1007/978-3-642-79803-0 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | The Endothelium in Cardiovascular Disease Pathophysiology, Clinical Presentation and Pharmacotherapy Cardiology Human Physiology Pharmacology/Toxicology Human physiology Toxicology Endothelium-derived relaxing factor (DE-588)4236888-1 gnd Kardiovaskuläre Krankheit (DE-588)4024666-8 gnd |
| subject_GND | (DE-588)4236888-1 (DE-588)4024666-8 (DE-588)4143413-4 |
| title | The Endothelium in Cardiovascular Disease Pathophysiology, Clinical Presentation and Pharmacotherapy |
| title_auth | The Endothelium in Cardiovascular Disease Pathophysiology, Clinical Presentation and Pharmacotherapy |
| title_exact_search | The Endothelium in Cardiovascular Disease Pathophysiology, Clinical Presentation and Pharmacotherapy |
| title_full | The Endothelium in Cardiovascular Disease Pathophysiology, Clinical Presentation and Pharmacotherapy edited by Thomas F. Lüscher |
| title_fullStr | The Endothelium in Cardiovascular Disease Pathophysiology, Clinical Presentation and Pharmacotherapy edited by Thomas F. Lüscher |
| title_full_unstemmed | The Endothelium in Cardiovascular Disease Pathophysiology, Clinical Presentation and Pharmacotherapy edited by Thomas F. Lüscher |
| title_short | The Endothelium in Cardiovascular Disease |
| title_sort | the endothelium in cardiovascular disease pathophysiology clinical presentation and pharmacotherapy |
| title_sub | Pathophysiology, Clinical Presentation and Pharmacotherapy |
| topic | Cardiology Human Physiology Pharmacology/Toxicology Human physiology Toxicology Endothelium-derived relaxing factor (DE-588)4236888-1 gnd Kardiovaskuläre Krankheit (DE-588)4024666-8 gnd |
| topic_facet | Cardiology Human Physiology Pharmacology/Toxicology Human physiology Toxicology Endothelium-derived relaxing factor Kardiovaskuläre Krankheit Aufsatzsammlung |
| url | https://doi.org/10.1007/978-3-642-79803-0 |
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