Growth Hormone II: Basic and Clinical Aspects
This book is a compendium of proceedings from the Symposium on Growth Hormone II: Basic and Clinical Aspects. The intent of the sym posium was to review current aspects of the rapidly expanding science of growth hormone (GH) neuroendocrinology, especially those develop ments that occurred since ou...
Gespeichert in:
| Weitere Verfasser: | , |
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| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
New York, NY
Springer New York
1994
|
| Schriftenreihe: | Serono Symposia USA
|
| Schlagworte: | |
| Online-Zugang: | UBR01 Volltext |
| Zusammenfassung: | This book is a compendium of proceedings from the Symposium on Growth Hormone II: Basic and Clinical Aspects. The intent of the sym posium was to review current aspects of the rapidly expanding science of growth hormone (GH) neuroendocrinology, especially those develop ments that occurred since our last meeting in 1985. The meeting was timely since there have been many new and exciting developments in basic research on the GH axis, and several new clinical applications for GH other than growth have been identified. For example, significant strides have been made into use of the bioengineered hormone as an anabolic in debilitated states and as an immunorestorative agent. Both these areas have received most attention as they relate to geriatric popu lations. Furthermore, recent focus on a novel family of GH secretagogues that complement the action of GHRH has shown that in animal models, these compounds have the potential to restore GH secretion in deficient or insufficient states, including growth retardation, obesity, and aging. Accordingly, these xenobiotics may have significant potential as drug products to stimulate physiological GH secretion and, thus, resist or reverse some of the maladaptive changes in form and function resulting from GH insufficiency. The importance of these agents as drug candidates is underscored by the diversity of molecules that have been studied by various pharmaceutical companies and the recent discovery that non peptide analogs with high oral bioavailability can be synthesized |
| Beschreibung: | 1 Online-Ressource (XX, 379 p) |
| ISBN: | 9781461383727 |
| DOI: | 10.1007/978-1-4613-8372-7 |
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| spelling | Growth Hormone II Basic and Clinical Aspects edited by Barry B. Bercu, Richard F. Walker New York, NY Springer New York 1994 1 Online-Ressource (XX, 379 p) txt rdacontent c rdamedia cr rdacarrier Serono Symposia USA This book is a compendium of proceedings from the Symposium on Growth Hormone II: Basic and Clinical Aspects. The intent of the sym posium was to review current aspects of the rapidly expanding science of growth hormone (GH) neuroendocrinology, especially those develop ments that occurred since our last meeting in 1985. The meeting was timely since there have been many new and exciting developments in basic research on the GH axis, and several new clinical applications for GH other than growth have been identified. For example, significant strides have been made into use of the bioengineered hormone as an anabolic in debilitated states and as an immunorestorative agent. Both these areas have received most attention as they relate to geriatric popu lations. Furthermore, recent focus on a novel family of GH secretagogues that complement the action of GHRH has shown that in animal models, these compounds have the potential to restore GH secretion in deficient or insufficient states, including growth retardation, obesity, and aging. Accordingly, these xenobiotics may have significant potential as drug products to stimulate physiological GH secretion and, thus, resist or reverse some of the maladaptive changes in form and function resulting from GH insufficiency. The importance of these agents as drug candidates is underscored by the diversity of molecules that have been studied by various pharmaceutical companies and the recent discovery that non peptide analogs with high oral bioavailability can be synthesized Neurosciences Human Physiology Cell Biology Animal Physiology Human physiology Cytology Animal physiology Somatotropin (DE-588)4137446-0 gnd rswk-swf (DE-588)1071861417 Konferenzschrift 1992 Tarpon Springs Fla. gnd-content (DE-588)1071861417 Konferenzschrift 1992 Tarpon Springs, Fla. gnd-content Somatotropin (DE-588)4137446-0 s DE-604 Bercu, Barry B. edt Walker, Richard F. edt Erscheint auch als Druck-Ausgabe 9781461383741 Erscheint auch als Druck-Ausgabe 9780387941332 Erscheint auch als Druck-Ausgabe 9781461383734 https://doi.org/10.1007/978-1-4613-8372-7 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Growth Hormone II Basic and Clinical Aspects Neurosciences Human Physiology Cell Biology Animal Physiology Human physiology Cytology Animal physiology Somatotropin (DE-588)4137446-0 gnd |
| subject_GND | (DE-588)4137446-0 (DE-588)1071861417 |
| title | Growth Hormone II Basic and Clinical Aspects |
| title_auth | Growth Hormone II Basic and Clinical Aspects |
| title_exact_search | Growth Hormone II Basic and Clinical Aspects |
| title_full | Growth Hormone II Basic and Clinical Aspects edited by Barry B. Bercu, Richard F. Walker |
| title_fullStr | Growth Hormone II Basic and Clinical Aspects edited by Barry B. Bercu, Richard F. Walker |
| title_full_unstemmed | Growth Hormone II Basic and Clinical Aspects edited by Barry B. Bercu, Richard F. Walker |
| title_short | Growth Hormone II |
| title_sort | growth hormone ii basic and clinical aspects |
| title_sub | Basic and Clinical Aspects |
| topic | Neurosciences Human Physiology Cell Biology Animal Physiology Human physiology Cytology Animal physiology Somatotropin (DE-588)4137446-0 gnd |
| topic_facet | Neurosciences Human Physiology Cell Biology Animal Physiology Human physiology Cytology Animal physiology Somatotropin Konferenzschrift 1992 Tarpon Springs Fla. Konferenzschrift 1992 Tarpon Springs, Fla. |
| url | https://doi.org/10.1007/978-1-4613-8372-7 |
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