Stunning, Hibernation, and Calcium in Myocardial Ischemia and Reperfusion:
Stunning is potentially an important complication of myocardial reperfusion. In contrast, hibernation is an important complication of myocardial ischemia. This book presents different viewpoints on these subjects, taken from a series of peer-reviewed articles which first appeared in Cardiovascular D...
Gespeichert in:
| Weitere Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Boston, MA
Springer US
1992
|
| Schlagworte: | |
| Online-Zugang: | UBR01 URL des Erstveröffentlichers |
| Zusammenfassung: | Stunning is potentially an important complication of myocardial reperfusion. In contrast, hibernation is an important complication of myocardial ischemia. This book presents different viewpoints on these subjects, taken from a series of peer-reviewed articles which first appeared in Cardiovascular Drugs and Therapy, and now in this book. In addition, a certain number of articles were directly invited for the book. The introductory article is by Eugene Braunwald, who with Kloner introduced the term myocardial stunning in 1982. The experimental phenomenon had first been described by Heyndrickx et al. This important concept of stunning is examined from a number of points of view in a series of articles which clarify the experimental causes and the clinical implications. The section on hibernation is introduced by Tubau and Rahimtoola, the latter having first propounded the concept in 1989. The difference between stunning and hibernation is that stunning is essentially a post-ischemic dysfunction of the myocardium, temporary in nature, occurring at a time when coronary blood flow is apparently normal or supranormal. Hibernation, on the other hand, is a condition of reduced contractile activity, the direct result of chronic ischemia and hence a sign of a tolerable reduction in blood flow. Possibly the reduction in contractile activity of the hibernating heart balances the reduction in the oxygen availability (the 'smart heart' of Rahimtoola). This non-contractile heart is hibernating, awaiting the return of summer after winter, and willing to contract normally again whenever warm coronary blood is restored. It is certain that the concepts of stunning and hibernation are here to stay, that they have or will have clinical relevance, and that the search for the most appropriate diagnosis and therapy for each condition is now under way. Hence, a greater understanding of the experimental work which underlies these two conditions is highly appropriate |
| Beschreibung: | 1 Online-Ressource (XII, 288 p. 5 illus) |
| ISBN: | 9781461315179 |
| DOI: | 10.1007/978-1-4613-1517-9 |
Internformat
MARC
| LEADER | 00000nmm a2200000zc 4500 | ||
|---|---|---|---|
| 001 | BV046144084 | ||
| 003 | DE-604 | ||
| 005 | 00000000000000.0 | ||
| 007 | cr|uuu---uuuuu | ||
| 008 | 190905s1992 |||| o||u| ||||||eng d | ||
| 020 | |a 9781461315179 |9 978-1-4613-1517-9 | ||
| 024 | 7 | |a 10.1007/978-1-4613-1517-9 |2 doi | |
| 035 | |a (ZDB-2-SME)978-1-4613-1517-9 | ||
| 035 | |a (OCoLC)1119104809 | ||
| 035 | |a (DE-599)BVBBV046144084 | ||
| 040 | |a DE-604 |b ger |e aacr | ||
| 041 | 0 | |a eng | |
| 049 | |a DE-355 | ||
| 082 | 0 | |a 616.12 |2 23 | |
| 245 | 1 | 0 | |a Stunning, Hibernation, and Calcium in Myocardial Ischemia and Reperfusion |c edited by Lionel H. Opie |
| 264 | 1 | |a Boston, MA |b Springer US |c 1992 | |
| 300 | |a 1 Online-Ressource (XII, 288 p. 5 illus) | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b c |2 rdamedia | ||
| 338 | |b cr |2 rdacarrier | ||
| 520 | |a Stunning is potentially an important complication of myocardial reperfusion. In contrast, hibernation is an important complication of myocardial ischemia. This book presents different viewpoints on these subjects, taken from a series of peer-reviewed articles which first appeared in Cardiovascular Drugs and Therapy, and now in this book. In addition, a certain number of articles were directly invited for the book. The introductory article is by Eugene Braunwald, who with Kloner introduced the term myocardial stunning in 1982. The experimental phenomenon had first been described by Heyndrickx et al. This important concept of stunning is examined from a number of points of view in a series of articles which clarify the experimental causes and the clinical implications. The section on hibernation is introduced by Tubau and Rahimtoola, the latter having first propounded the concept in 1989. The difference between stunning and hibernation is that stunning is essentially a post-ischemic dysfunction of the myocardium, temporary in nature, occurring at a time when coronary blood flow is apparently normal or supranormal. Hibernation, on the other hand, is a condition of reduced contractile activity, the direct result of chronic ischemia and hence a sign of a tolerable reduction in blood flow. Possibly the reduction in contractile activity of the hibernating heart balances the reduction in the oxygen availability (the 'smart heart' of Rahimtoola). This non-contractile heart is hibernating, awaiting the return of summer after winter, and willing to contract normally again whenever warm coronary blood is restored. It is certain that the concepts of stunning and hibernation are here to stay, that they have or will have clinical relevance, and that the search for the most appropriate diagnosis and therapy for each condition is now under way. Hence, a greater understanding of the experimental work which underlies these two conditions is highly appropriate | ||
| 650 | 4 | |a Cardiology | |
| 650 | 4 | |a Cardiology | |
| 650 | 0 | 7 | |a Muskelkontraktion |0 (DE-588)4170858-1 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Ischämie |0 (DE-588)4162456-7 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Herzmuskel |0 (DE-588)4024675-9 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Postischämiesyndrom |0 (DE-588)4195222-4 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Herzkrankheit |0 (DE-588)4024663-2 |2 gnd |9 rswk-swf |
| 655 | 7 | |8 1\p |0 (DE-588)1071861417 |a Konferenzschrift |2 gnd-content | |
| 689 | 0 | 0 | |a Herzkrankheit |0 (DE-588)4024663-2 |D s |
| 689 | 0 | 1 | |a Ischämie |0 (DE-588)4162456-7 |D s |
| 689 | 0 | 2 | |a Muskelkontraktion |0 (DE-588)4170858-1 |D s |
| 689 | 0 | |8 2\p |5 DE-604 | |
| 689 | 1 | 0 | |a Herzmuskel |0 (DE-588)4024675-9 |D s |
| 689 | 1 | 1 | |a Postischämiesyndrom |0 (DE-588)4195222-4 |D s |
| 689 | 1 | |8 3\p |5 DE-604 | |
| 700 | 1 | |a Opie, Lionel H. |4 edt | |
| 776 | 0 | 8 | |i Erscheint auch als |n Druck-Ausgabe |z 9780792317937 |
| 776 | 0 | 8 | |i Erscheint auch als |n Druck-Ausgabe |z 9781461315186 |
| 856 | 4 | 0 | |u https://doi.org/10.1007/978-1-4613-1517-9 |x Verlag |z URL des Erstveröffentlichers |3 Volltext |
| 912 | |a ZDB-2-SME | ||
| 940 | 1 | |q ZDB-2-SME_1990/2004 | |
| 999 | |a oai:aleph.bib-bvb.de:BVB01-031524268 | ||
| 883 | 1 | |8 1\p |a cgwrk |d 20201028 |q DE-101 |u https://d-nb.info/provenance/plan#cgwrk | |
| 883 | 1 | |8 2\p |a cgwrk |d 20201028 |q DE-101 |u https://d-nb.info/provenance/plan#cgwrk | |
| 883 | 1 | |8 3\p |a cgwrk |d 20201028 |q DE-101 |u https://d-nb.info/provenance/plan#cgwrk | |
| 966 | e | |u https://doi.org/10.1007/978-1-4613-1517-9 |l UBR01 |p ZDB-2-SME |q ZDB-2-SME_1990/2004 |x Verlag |3 Volltext | |
Datensatz im Suchindex
| _version_ | 1804180479000182784 |
|---|---|
| any_adam_object | |
| author2 | Opie, Lionel H. |
| author2_role | edt |
| author2_variant | l h o lh lho |
| author_facet | Opie, Lionel H. |
| building | Verbundindex |
| bvnumber | BV046144084 |
| collection | ZDB-2-SME |
| ctrlnum | (ZDB-2-SME)978-1-4613-1517-9 (OCoLC)1119104809 (DE-599)BVBBV046144084 |
| dewey-full | 616.12 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 616 - Diseases |
| dewey-raw | 616.12 |
| dewey-search | 616.12 |
| dewey-sort | 3616.12 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| doi_str_mv | 10.1007/978-1-4613-1517-9 |
| format | Electronic eBook |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>04328nmm a2200589zc 4500</leader><controlfield tag="001">BV046144084</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">00000000000000.0</controlfield><controlfield tag="007">cr|uuu---uuuuu</controlfield><controlfield tag="008">190905s1992 |||| o||u| ||||||eng d</controlfield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9781461315179</subfield><subfield code="9">978-1-4613-1517-9</subfield></datafield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1007/978-1-4613-1517-9</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ZDB-2-SME)978-1-4613-1517-9</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)1119104809</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV046144084</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">aacr</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-355</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">616.12</subfield><subfield code="2">23</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Stunning, Hibernation, and Calcium in Myocardial Ischemia and Reperfusion</subfield><subfield code="c">edited by Lionel H. Opie</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Boston, MA</subfield><subfield code="b">Springer US</subfield><subfield code="c">1992</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 Online-Ressource (XII, 288 p. 5 illus)</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Stunning is potentially an important complication of myocardial reperfusion. In contrast, hibernation is an important complication of myocardial ischemia. This book presents different viewpoints on these subjects, taken from a series of peer-reviewed articles which first appeared in Cardiovascular Drugs and Therapy, and now in this book. In addition, a certain number of articles were directly invited for the book. The introductory article is by Eugene Braunwald, who with Kloner introduced the term myocardial stunning in 1982. The experimental phenomenon had first been described by Heyndrickx et al. This important concept of stunning is examined from a number of points of view in a series of articles which clarify the experimental causes and the clinical implications. The section on hibernation is introduced by Tubau and Rahimtoola, the latter having first propounded the concept in 1989. The difference between stunning and hibernation is that stunning is essentially a post-ischemic dysfunction of the myocardium, temporary in nature, occurring at a time when coronary blood flow is apparently normal or supranormal. Hibernation, on the other hand, is a condition of reduced contractile activity, the direct result of chronic ischemia and hence a sign of a tolerable reduction in blood flow. Possibly the reduction in contractile activity of the hibernating heart balances the reduction in the oxygen availability (the 'smart heart' of Rahimtoola). This non-contractile heart is hibernating, awaiting the return of summer after winter, and willing to contract normally again whenever warm coronary blood is restored. It is certain that the concepts of stunning and hibernation are here to stay, that they have or will have clinical relevance, and that the search for the most appropriate diagnosis and therapy for each condition is now under way. Hence, a greater understanding of the experimental work which underlies these two conditions is highly appropriate</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Cardiology</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Cardiology</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Muskelkontraktion</subfield><subfield code="0">(DE-588)4170858-1</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Ischämie</subfield><subfield code="0">(DE-588)4162456-7</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Herzmuskel</subfield><subfield code="0">(DE-588)4024675-9</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Postischämiesyndrom</subfield><subfield code="0">(DE-588)4195222-4</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Herzkrankheit</subfield><subfield code="0">(DE-588)4024663-2</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="655" ind1=" " ind2="7"><subfield code="8">1\p</subfield><subfield code="0">(DE-588)1071861417</subfield><subfield code="a">Konferenzschrift</subfield><subfield code="2">gnd-content</subfield></datafield><datafield tag="689" ind1="0" ind2="0"><subfield code="a">Herzkrankheit</subfield><subfield code="0">(DE-588)4024663-2</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="1"><subfield code="a">Ischämie</subfield><subfield code="0">(DE-588)4162456-7</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="2"><subfield code="a">Muskelkontraktion</subfield><subfield code="0">(DE-588)4170858-1</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2=" "><subfield code="8">2\p</subfield><subfield code="5">DE-604</subfield></datafield><datafield tag="689" ind1="1" ind2="0"><subfield code="a">Herzmuskel</subfield><subfield code="0">(DE-588)4024675-9</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="1" ind2="1"><subfield code="a">Postischämiesyndrom</subfield><subfield code="0">(DE-588)4195222-4</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="1" ind2=" "><subfield code="8">3\p</subfield><subfield code="5">DE-604</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Opie, Lionel H.</subfield><subfield code="4">edt</subfield></datafield><datafield tag="776" ind1="0" ind2="8"><subfield code="i">Erscheint auch als</subfield><subfield code="n">Druck-Ausgabe</subfield><subfield code="z">9780792317937</subfield></datafield><datafield tag="776" ind1="0" ind2="8"><subfield code="i">Erscheint auch als</subfield><subfield code="n">Druck-Ausgabe</subfield><subfield code="z">9781461315186</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.1007/978-1-4613-1517-9</subfield><subfield code="x">Verlag</subfield><subfield code="z">URL des Erstveröffentlichers</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-2-SME</subfield></datafield><datafield tag="940" ind1="1" ind2=" "><subfield code="q">ZDB-2-SME_1990/2004</subfield></datafield><datafield tag="999" ind1=" " ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-031524268</subfield></datafield><datafield tag="883" ind1="1" ind2=" "><subfield code="8">1\p</subfield><subfield code="a">cgwrk</subfield><subfield code="d">20201028</subfield><subfield code="q">DE-101</subfield><subfield code="u">https://d-nb.info/provenance/plan#cgwrk</subfield></datafield><datafield tag="883" ind1="1" ind2=" "><subfield code="8">2\p</subfield><subfield code="a">cgwrk</subfield><subfield code="d">20201028</subfield><subfield code="q">DE-101</subfield><subfield code="u">https://d-nb.info/provenance/plan#cgwrk</subfield></datafield><datafield tag="883" ind1="1" ind2=" "><subfield code="8">3\p</subfield><subfield code="a">cgwrk</subfield><subfield code="d">20201028</subfield><subfield code="q">DE-101</subfield><subfield code="u">https://d-nb.info/provenance/plan#cgwrk</subfield></datafield><datafield tag="966" ind1="e" ind2=" "><subfield code="u">https://doi.org/10.1007/978-1-4613-1517-9</subfield><subfield code="l">UBR01</subfield><subfield code="p">ZDB-2-SME</subfield><subfield code="q">ZDB-2-SME_1990/2004</subfield><subfield code="x">Verlag</subfield><subfield code="3">Volltext</subfield></datafield></record></collection> |
| genre | 1\p (DE-588)1071861417 Konferenzschrift gnd-content |
| genre_facet | Konferenzschrift |
| id | DE-604.BV046144084 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T08:36:24Z |
| institution | BVB |
| isbn | 9781461315179 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-031524268 |
| oclc_num | 1119104809 |
| open_access_boolean | |
| owner | DE-355 DE-BY-UBR |
| owner_facet | DE-355 DE-BY-UBR |
| physical | 1 Online-Ressource (XII, 288 p. 5 illus) |
| psigel | ZDB-2-SME ZDB-2-SME_1990/2004 ZDB-2-SME ZDB-2-SME_1990/2004 |
| publishDate | 1992 |
| publishDateSearch | 1992 |
| publishDateSort | 1992 |
| publisher | Springer US |
| record_format | marc |
| spelling | Stunning, Hibernation, and Calcium in Myocardial Ischemia and Reperfusion edited by Lionel H. Opie Boston, MA Springer US 1992 1 Online-Ressource (XII, 288 p. 5 illus) txt rdacontent c rdamedia cr rdacarrier Stunning is potentially an important complication of myocardial reperfusion. In contrast, hibernation is an important complication of myocardial ischemia. This book presents different viewpoints on these subjects, taken from a series of peer-reviewed articles which first appeared in Cardiovascular Drugs and Therapy, and now in this book. In addition, a certain number of articles were directly invited for the book. The introductory article is by Eugene Braunwald, who with Kloner introduced the term myocardial stunning in 1982. The experimental phenomenon had first been described by Heyndrickx et al. This important concept of stunning is examined from a number of points of view in a series of articles which clarify the experimental causes and the clinical implications. The section on hibernation is introduced by Tubau and Rahimtoola, the latter having first propounded the concept in 1989. The difference between stunning and hibernation is that stunning is essentially a post-ischemic dysfunction of the myocardium, temporary in nature, occurring at a time when coronary blood flow is apparently normal or supranormal. Hibernation, on the other hand, is a condition of reduced contractile activity, the direct result of chronic ischemia and hence a sign of a tolerable reduction in blood flow. Possibly the reduction in contractile activity of the hibernating heart balances the reduction in the oxygen availability (the 'smart heart' of Rahimtoola). This non-contractile heart is hibernating, awaiting the return of summer after winter, and willing to contract normally again whenever warm coronary blood is restored. It is certain that the concepts of stunning and hibernation are here to stay, that they have or will have clinical relevance, and that the search for the most appropriate diagnosis and therapy for each condition is now under way. Hence, a greater understanding of the experimental work which underlies these two conditions is highly appropriate Cardiology Muskelkontraktion (DE-588)4170858-1 gnd rswk-swf Ischämie (DE-588)4162456-7 gnd rswk-swf Herzmuskel (DE-588)4024675-9 gnd rswk-swf Postischämiesyndrom (DE-588)4195222-4 gnd rswk-swf Herzkrankheit (DE-588)4024663-2 gnd rswk-swf 1\p (DE-588)1071861417 Konferenzschrift gnd-content Herzkrankheit (DE-588)4024663-2 s Ischämie (DE-588)4162456-7 s Muskelkontraktion (DE-588)4170858-1 s 2\p DE-604 Herzmuskel (DE-588)4024675-9 s Postischämiesyndrom (DE-588)4195222-4 s 3\p DE-604 Opie, Lionel H. edt Erscheint auch als Druck-Ausgabe 9780792317937 Erscheint auch als Druck-Ausgabe 9781461315186 https://doi.org/10.1007/978-1-4613-1517-9 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 2\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 3\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Stunning, Hibernation, and Calcium in Myocardial Ischemia and Reperfusion Cardiology Muskelkontraktion (DE-588)4170858-1 gnd Ischämie (DE-588)4162456-7 gnd Herzmuskel (DE-588)4024675-9 gnd Postischämiesyndrom (DE-588)4195222-4 gnd Herzkrankheit (DE-588)4024663-2 gnd |
| subject_GND | (DE-588)4170858-1 (DE-588)4162456-7 (DE-588)4024675-9 (DE-588)4195222-4 (DE-588)4024663-2 (DE-588)1071861417 |
| title | Stunning, Hibernation, and Calcium in Myocardial Ischemia and Reperfusion |
| title_auth | Stunning, Hibernation, and Calcium in Myocardial Ischemia and Reperfusion |
| title_exact_search | Stunning, Hibernation, and Calcium in Myocardial Ischemia and Reperfusion |
| title_full | Stunning, Hibernation, and Calcium in Myocardial Ischemia and Reperfusion edited by Lionel H. Opie |
| title_fullStr | Stunning, Hibernation, and Calcium in Myocardial Ischemia and Reperfusion edited by Lionel H. Opie |
| title_full_unstemmed | Stunning, Hibernation, and Calcium in Myocardial Ischemia and Reperfusion edited by Lionel H. Opie |
| title_short | Stunning, Hibernation, and Calcium in Myocardial Ischemia and Reperfusion |
| title_sort | stunning hibernation and calcium in myocardial ischemia and reperfusion |
| topic | Cardiology Muskelkontraktion (DE-588)4170858-1 gnd Ischämie (DE-588)4162456-7 gnd Herzmuskel (DE-588)4024675-9 gnd Postischämiesyndrom (DE-588)4195222-4 gnd Herzkrankheit (DE-588)4024663-2 gnd |
| topic_facet | Cardiology Muskelkontraktion Ischämie Herzmuskel Postischämiesyndrom Herzkrankheit Konferenzschrift |
| url | https://doi.org/10.1007/978-1-4613-1517-9 |
| work_keys_str_mv | AT opielionelh stunninghibernationandcalciuminmyocardialischemiaandreperfusion |