Arteriosclerosis: New Insights into Pathogenetic Mechanisms and Prevention
A vast literature has been concerned with arteriosclerosis and yet, many aspects of pathogenesis and of the mechanism of development of the arteriosclerotic vascular lesion remain only poorly understood. In recent years, our knowledge of the earliest stages of arteriosclerosis have greatly improved....
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| Weitere Verfasser: | , , |
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| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Heidelberg
Steinkopff
1994
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| Schlagworte: | |
| Online-Zugang: | UBR01 URL des Erstveröffentlichers |
| Zusammenfassung: | A vast literature has been concerned with arteriosclerosis and yet, many aspects of pathogenesis and of the mechanism of development of the arteriosclerotic vascular lesion remain only poorly understood. In recent years, our knowledge of the earliest stages of arteriosclerosis have greatly improved. By now, we have learned to relate morphologic changes to disturbances in function. It has been of particular impor tance that components of the arterial wall could be analyzed in regard to dysfunction, for example, in the endothelium or the vascular smooth muscle. The interaction of the different morphological components of the vascular wall could thus be much bet ter understood. Likewise, the interaction between the arterial wall and the flowing blood could be much better described, including the intimate relationship between platelets and the endothelium, the coagulation system and the endothelium, the granulocytes and the endothelial cell layer, as well as processes of migration of blood cells into the subendothelial space. The recognition of functional and morphological disturbance has attained clinical significance not only because the arteriosclerotic diseases have quantitatively reached the dimensions of an epidemic, that is, of a magnitude never been witnessed. It is also because of the development of new drugs that interfere with the atherogenic process and thereby prevent the development of the disease or halt its progression. It is also becoming increasingly possible to inhibit the occurrence of complications in existing arteriosclerotic lesions in manifest disease, i. e |
| Beschreibung: | 1 Online-Ressource (X, 202 p) |
| ISBN: | 9783642856600 |
| DOI: | 10.1007/978-3-642-85660-0 |
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| 520 | |a A vast literature has been concerned with arteriosclerosis and yet, many aspects of pathogenesis and of the mechanism of development of the arteriosclerotic vascular lesion remain only poorly understood. In recent years, our knowledge of the earliest stages of arteriosclerosis have greatly improved. By now, we have learned to relate morphologic changes to disturbances in function. It has been of particular impor tance that components of the arterial wall could be analyzed in regard to dysfunction, for example, in the endothelium or the vascular smooth muscle. The interaction of the different morphological components of the vascular wall could thus be much bet ter understood. Likewise, the interaction between the arterial wall and the flowing blood could be much better described, including the intimate relationship between platelets and the endothelium, the coagulation system and the endothelium, the granulocytes and the endothelial cell layer, as well as processes of migration of blood cells into the subendothelial space. The recognition of functional and morphological disturbance has attained clinical significance not only because the arteriosclerotic diseases have quantitatively reached the dimensions of an epidemic, that is, of a magnitude never been witnessed. It is also because of the development of new drugs that interfere with the atherogenic process and thereby prevent the development of the disease or halt its progression. It is also becoming increasingly possible to inhibit the occurrence of complications in existing arteriosclerotic lesions in manifest disease, i. e | ||
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| spelling | Arteriosclerosis New Insights into Pathogenetic Mechanisms and Prevention edited by H. Just, W. Hort, A. M. Zeiher Heidelberg Steinkopff 1994 1 Online-Ressource (X, 202 p) txt rdacontent c rdamedia cr rdacarrier A vast literature has been concerned with arteriosclerosis and yet, many aspects of pathogenesis and of the mechanism of development of the arteriosclerotic vascular lesion remain only poorly understood. In recent years, our knowledge of the earliest stages of arteriosclerosis have greatly improved. By now, we have learned to relate morphologic changes to disturbances in function. It has been of particular impor tance that components of the arterial wall could be analyzed in regard to dysfunction, for example, in the endothelium or the vascular smooth muscle. The interaction of the different morphological components of the vascular wall could thus be much bet ter understood. Likewise, the interaction between the arterial wall and the flowing blood could be much better described, including the intimate relationship between platelets and the endothelium, the coagulation system and the endothelium, the granulocytes and the endothelial cell layer, as well as processes of migration of blood cells into the subendothelial space. The recognition of functional and morphological disturbance has attained clinical significance not only because the arteriosclerotic diseases have quantitatively reached the dimensions of an epidemic, that is, of a magnitude never been witnessed. It is also because of the development of new drugs that interfere with the atherogenic process and thereby prevent the development of the disease or halt its progression. It is also becoming increasingly possible to inhibit the occurrence of complications in existing arteriosclerotic lesions in manifest disease, i. e Cardiology Human Physiology Human physiology Arteriosklerose (DE-588)4068866-5 gnd rswk-swf (DE-588)1071861417 Konferenzschrift 1992 Gargellen gnd-content Arteriosklerose (DE-588)4068866-5 s DE-604 Just, H. edt Hort, W. edt Zeiher, A. M. edt Erscheint auch als Druck-Ausgabe 9783642856624 Erscheint auch als Druck-Ausgabe 9783798509375 Erscheint auch als Druck-Ausgabe 9783642856617 https://doi.org/10.1007/978-3-642-85660-0 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Arteriosclerosis New Insights into Pathogenetic Mechanisms and Prevention Cardiology Human Physiology Human physiology Arteriosklerose (DE-588)4068866-5 gnd |
| subject_GND | (DE-588)4068866-5 (DE-588)1071861417 |
| title | Arteriosclerosis New Insights into Pathogenetic Mechanisms and Prevention |
| title_auth | Arteriosclerosis New Insights into Pathogenetic Mechanisms and Prevention |
| title_exact_search | Arteriosclerosis New Insights into Pathogenetic Mechanisms and Prevention |
| title_full | Arteriosclerosis New Insights into Pathogenetic Mechanisms and Prevention edited by H. Just, W. Hort, A. M. Zeiher |
| title_fullStr | Arteriosclerosis New Insights into Pathogenetic Mechanisms and Prevention edited by H. Just, W. Hort, A. M. Zeiher |
| title_full_unstemmed | Arteriosclerosis New Insights into Pathogenetic Mechanisms and Prevention edited by H. Just, W. Hort, A. M. Zeiher |
| title_short | Arteriosclerosis |
| title_sort | arteriosclerosis new insights into pathogenetic mechanisms and prevention |
| title_sub | New Insights into Pathogenetic Mechanisms and Prevention |
| topic | Cardiology Human Physiology Human physiology Arteriosklerose (DE-588)4068866-5 gnd |
| topic_facet | Cardiology Human Physiology Human physiology Arteriosklerose Konferenzschrift 1992 Gargellen |
| url | https://doi.org/10.1007/978-3-642-85660-0 |
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