Endothelial Mechanisms of Vasomotor Control: With special Reference to the Coronary Circulation
In recent years, we have witnessed a rapid expansion of our knowledge regarding the role of the endothelium in the control of vascular tone (and organ perfusion) in health and disease. Physiology, pharmacology, and molecular biology have uncovered a wealth of information on structure and function of...
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| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Heidelberg
Steinkopff
1991
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| Schlagworte: | |
| Online-Zugang: | UBR01 URL des Erstveröffentlichers |
| Zusammenfassung: | In recent years, we have witnessed a rapid expansion of our knowledge regarding the role of the endothelium in the control of vascular tone (and organ perfusion) in health and disease. Physiology, pharmacology, and molecular biology have uncovered a wealth of information on structure and function of this heretofore largely neglected "organ". Clinical medicine is now called upon to define the clinical significance of these observa tions that imply the mechanisms of blood coagulation, e.g., the interaction of throm bocytes with the endothelium, vasomotor control, and specifically, the regulation of smooth muscle tone with consequences for vascular resistance and conductance and organ blood flow. Finally, metabolism of lipids with the everlasting problem of athero sclerosis is an important aspect. In a second step, implications regarding the improvement of current therapeutic con cepts, as well as the development of new modalities of pharmacotherapy will have to be discussed. The topic addressed by the 1990 Gargellen Conference: Endothelial Mechanisms of Vasomotor Control, clearly is of interest for both basic scientists and clinicians. It has been the aim of the organizers, the Society for Cooperation in Medical Science (SCMS) with this and the previous symposia to foster and support both basic science and clinical research. Research in medicine today shows two major directions of development: on the one hand, increasing involvement of the basic sciences and their methodology. On the other hand, statistical validation of concepts and therapeutic strategies in large scale population-and multicenter-studies |
| Beschreibung: | 1 Online-Ressource (VIII, 246 p) |
| ISBN: | 9783642724619 |
| DOI: | 10.1007/978-3-642-72461-9 |
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| 520 | |a In recent years, we have witnessed a rapid expansion of our knowledge regarding the role of the endothelium in the control of vascular tone (and organ perfusion) in health and disease. Physiology, pharmacology, and molecular biology have uncovered a wealth of information on structure and function of this heretofore largely neglected "organ". Clinical medicine is now called upon to define the clinical significance of these observa tions that imply the mechanisms of blood coagulation, e.g., the interaction of throm bocytes with the endothelium, vasomotor control, and specifically, the regulation of smooth muscle tone with consequences for vascular resistance and conductance and organ blood flow. Finally, metabolism of lipids with the everlasting problem of athero sclerosis is an important aspect. In a second step, implications regarding the improvement of current therapeutic con cepts, as well as the development of new modalities of pharmacotherapy will have to be discussed. The topic addressed by the 1990 Gargellen Conference: Endothelial Mechanisms of Vasomotor Control, clearly is of interest for both basic scientists and clinicians. It has been the aim of the organizers, the Society for Cooperation in Medical Science (SCMS) with this and the previous symposia to foster and support both basic science and clinical research. Research in medicine today shows two major directions of development: on the one hand, increasing involvement of the basic sciences and their methodology. On the other hand, statistical validation of concepts and therapeutic strategies in large scale population-and multicenter-studies | ||
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| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 616 - Diseases |
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| dewey-search | 616.12 |
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| discipline | Biologie Medizin |
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| id | DE-604.BV046143984 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T08:36:24Z |
| institution | BVB |
| isbn | 9783642724619 |
| language | English |
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| spelling | Endothelial Mechanisms of Vasomotor Control With special Reference to the Coronary Circulation edited by H. Drexler, A. M. Zeiher, E. Bassenge, H. Just Heidelberg Steinkopff 1991 1 Online-Ressource (VIII, 246 p) txt rdacontent c rdamedia cr rdacarrier In recent years, we have witnessed a rapid expansion of our knowledge regarding the role of the endothelium in the control of vascular tone (and organ perfusion) in health and disease. Physiology, pharmacology, and molecular biology have uncovered a wealth of information on structure and function of this heretofore largely neglected "organ". Clinical medicine is now called upon to define the clinical significance of these observa tions that imply the mechanisms of blood coagulation, e.g., the interaction of throm bocytes with the endothelium, vasomotor control, and specifically, the regulation of smooth muscle tone with consequences for vascular resistance and conductance and organ blood flow. Finally, metabolism of lipids with the everlasting problem of athero sclerosis is an important aspect. In a second step, implications regarding the improvement of current therapeutic con cepts, as well as the development of new modalities of pharmacotherapy will have to be discussed. The topic addressed by the 1990 Gargellen Conference: Endothelial Mechanisms of Vasomotor Control, clearly is of interest for both basic scientists and clinicians. It has been the aim of the organizers, the Society for Cooperation in Medical Science (SCMS) with this and the previous symposia to foster and support both basic science and clinical research. Research in medicine today shows two major directions of development: on the one hand, increasing involvement of the basic sciences and their methodology. On the other hand, statistical validation of concepts and therapeutic strategies in large scale population-and multicenter-studies Cardiology Human Physiology Human physiology Endothel (DE-588)4014675-3 gnd rswk-swf Koronardurchblutung (DE-588)4165327-0 gnd rswk-swf Endothelium-derived relaxing factor (DE-588)4236888-1 gnd rswk-swf Vasomotorik (DE-588)4187432-8 gnd rswk-swf (DE-588)1071861417 Konferenzschrift 1990 Gargellen gnd-content Endothelium-derived relaxing factor (DE-588)4236888-1 s Koronardurchblutung (DE-588)4165327-0 s DE-604 Vasomotorik (DE-588)4187432-8 s Endothel (DE-588)4014675-3 s Drexler, H. edt Zeiher, A. M. edt Bassenge, E. edt Just, H. edt Erscheint auch als Druck-Ausgabe 9783642724633 Erscheint auch als Druck-Ausgabe 9783798508668 Erscheint auch als Druck-Ausgabe 9783642724626 https://doi.org/10.1007/978-3-642-72461-9 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Endothelial Mechanisms of Vasomotor Control With special Reference to the Coronary Circulation Cardiology Human Physiology Human physiology Endothel (DE-588)4014675-3 gnd Koronardurchblutung (DE-588)4165327-0 gnd Endothelium-derived relaxing factor (DE-588)4236888-1 gnd Vasomotorik (DE-588)4187432-8 gnd |
| subject_GND | (DE-588)4014675-3 (DE-588)4165327-0 (DE-588)4236888-1 (DE-588)4187432-8 (DE-588)1071861417 |
| title | Endothelial Mechanisms of Vasomotor Control With special Reference to the Coronary Circulation |
| title_auth | Endothelial Mechanisms of Vasomotor Control With special Reference to the Coronary Circulation |
| title_exact_search | Endothelial Mechanisms of Vasomotor Control With special Reference to the Coronary Circulation |
| title_full | Endothelial Mechanisms of Vasomotor Control With special Reference to the Coronary Circulation edited by H. Drexler, A. M. Zeiher, E. Bassenge, H. Just |
| title_fullStr | Endothelial Mechanisms of Vasomotor Control With special Reference to the Coronary Circulation edited by H. Drexler, A. M. Zeiher, E. Bassenge, H. Just |
| title_full_unstemmed | Endothelial Mechanisms of Vasomotor Control With special Reference to the Coronary Circulation edited by H. Drexler, A. M. Zeiher, E. Bassenge, H. Just |
| title_short | Endothelial Mechanisms of Vasomotor Control |
| title_sort | endothelial mechanisms of vasomotor control with special reference to the coronary circulation |
| title_sub | With special Reference to the Coronary Circulation |
| topic | Cardiology Human Physiology Human physiology Endothel (DE-588)4014675-3 gnd Koronardurchblutung (DE-588)4165327-0 gnd Endothelium-derived relaxing factor (DE-588)4236888-1 gnd Vasomotorik (DE-588)4187432-8 gnd |
| topic_facet | Cardiology Human Physiology Human physiology Endothel Koronardurchblutung Endothelium-derived relaxing factor Vasomotorik Konferenzschrift 1990 Gargellen |
| url | https://doi.org/10.1007/978-3-642-72461-9 |
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